Patents by Inventor Jun Takeuchi

Jun Takeuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10501442
    Abstract: A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: December 10, 2019
    Assignee: ONO PHARMACEUTICALS CO., LTD.
    Inventors: Takayuki Inukai, Jun Takeuchi, Tomoko Yasuhiro
  • Patent number: 10459831
    Abstract: A data specification method executed by a computer, the method including obtaining a plurality of data groups, specifying a number of types of a plurality of values included in each of the plurality of data groups, obtaining a result of a calculation process using a plurality of values included in a specified data group, specifying a number of types of the plurality of values included in the specified data group, selecting one or more data groups based on the number of types of the plurality of values included in the specified data group and based on the number of types of the plurality of values included in each of the plurality of data groups, and specifying a corresponding data group corresponding to the specified data group from among the selected one or more data groups.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: October 29, 2019
    Assignee: FUJITSU LIMITED
    Inventors: Jun Ikeshima, Masashi Katou, Keigo Mitsumori, Yuta Kojima, Eiichi Higuchi, Yukihiro Takeuchi, Daiki Yoshikawa, Shotaro Okada, Kiyoshi Kouge
  • Publication number: 20190313951
    Abstract: An organism analyzing apparatus includes an information acquiring section configured to acquire an amount of change in a blood glucose level due to ingestion of an organism and a sugar-content estimating section configured to estimate, according to the amount of change in the blood glucose level, sugar content ingested by the organism through the ingestion.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 17, 2019
    Applicant: SEIKO EPSON CORPORATION
    Inventor: Jun TAKEUCHI
  • Publication number: 20190301605
    Abstract: A control apparatus for a vehicle transmission that includes: transmission gears disposed on a shaft; a switching mechanism which is to be switched between a connecting state in which one of the transmission gears is rotatable integrally with the shaft and a disconnecting state in which the one of the transmission gears is rotatable relative to the shaft; a shift fork for axially moving the switching mechanism; and a shift barrel to be rotated to position the shift fork. The switching mechanism includes first and second rings and an elastic member which is disposed between the first and second rings in the axial direction and connects the first and second rings. The control apparatus determines that a failure occurs in the vehicle transmission, when a value related to a reaction force that acts on the shift barrel during rotation of the shift barrel is deviated from a predetermined range.
    Type: Application
    Filed: March 19, 2019
    Publication date: October 3, 2019
    Applicants: Toyota Jidosha Kabushiki Kaisha, Aisin AI Co., Ltd.
    Inventors: Tomoyasu Kurimoto, Akihiko Ichikawa, Shinichi Takeuchi, Jun Yabuta, Yuki Masui, Takeshi Yano
  • Publication number: 20190288107
    Abstract: A silicon carbide semiconductor device includes: a substrate; a drift layer over the substrate; a base region over the drift layer; multiple source regions over an upper layer portion of the base region; a contact region over the upper layer portion of the base region between opposing source regions; multiple trenches from a surface of each source region to a depth deeper than the base region; a gate electrode on a gate insulating film in each trench; a source electrode electrically connected to the source regions and the contact region; a drain electrode over a rear surface of the substrate; and multiple electric field relaxation layers in the drift layer between adjacent trenches. Each electric field relaxation layer includes: a first region at a position deeper than the trenches; and a second region from a surface of the drift layer to the first region.
    Type: Application
    Filed: May 24, 2019
    Publication date: September 19, 2019
    Inventors: Hirotaka SAIKAKU, Jun SAKAKIBARA, Shoji MIZUNO, Yuichi TAKEUCHI
  • Patent number: 10399959
    Abstract: In order to provide a prophylactic and/or therapeutic agent for Trk-related diseases, the present invention provides a compound which has a selective Trk-inhibiting activity and persistently inhibits NGF vascular hyper permeability and does not have a drug interaction and in addition thereto, is excellent in solubility and absorbability against free bases. The compound of the present invention has a selective Trk-inhibiting activity and persistently inhibits NGF vascular hyper permeability and does not have a drug interaction and is excellent in solubility and absorbability against free bases, and is therefore useful as a prophylactic and/or therapeutic agent for Trk-related diseases.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: September 3, 2019
    Assignee: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Jun Takeuchi, Satoshi Itadani, Masahiro Ikura, Masato Higashino, Hideomi Kijima, Shizuka Ono, Tetsuya Yasuhiro, Takeshi Nagaura
  • Publication number: 20190242442
    Abstract: A dog clutch includes a gear (40) mounted on a power transmission shaft (30), first and second dog rings (10, 20), a fork (60), springs (65), and cam grooves (31). The cam grooves (31) each include a first slope surface (36) inclined from the axial direction toward the positive rotation direction as the first slope surface (36) approaches the gear (40) and a second parallel surface (37) parallel to the axial direction. The first dog ring (10) includes first cam protrusions (16) to be engaged with the respective first slope surfaces (36), and the second dog ring (20) includes second cam protrusions (26) to be engaged with the respective second parallel surfaces (37). This structure prevents the dog rings and the fork from coming into contact with each other, thereby avoiding generation of abrasion and increasing the transmission efficiency.
    Type: Application
    Filed: January 30, 2018
    Publication date: August 8, 2019
    Applicants: KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO, AISIN AI CO., LTD.
    Inventors: Isamu SHIOTSU, Shinichi TAKEUCHI, Akihiko ICHIKAWA, Junichi MURAOKA, Tomohiro YOSHIMURA, Jun YABUTA, Yuuki MASUI
  • Patent number: 10374079
    Abstract: A silicon carbide semiconductor device includes: a substrate; a drift layer over the substrate; a base region over the drift layer; multiple source regions over an upper layer portion of the base region; a contact region over the upper layer portion of the base region between opposing source regions; multiple trenches from a surface of each source region to a depth deeper than the base region; a gate electrode on a gate insulating film in each trench; a source electrode electrically connected to the source regions and the contact region; a drain electrode over a rear surface of the substrate; and multiple electric field relaxation layers in the drift layer between adjacent trenches. Each electric field relaxation layer includes: a first region at a position deeper than the trenches; and a second region from a surface of the drift layer to the first region.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: August 6, 2019
    Assignees: DENSO CORPORATION, TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Hirotaka Saikaku, Jun Sakakibara, Shoji Mizuno, Yuichi Takeuchi
  • Publication number: 20190231777
    Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.
    Type: Application
    Filed: April 5, 2019
    Publication date: August 1, 2019
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Jun TAKEUCHI, Satoshi ITADANI, Kazuya HASHIMURA, Masahiro IKURA, Masato HIGASHINO, Tetsuya YASUHIRO, Takeshi NAGAURA
  • Publication number: 20190235474
    Abstract: A method for generating a numerical control program includes first-fourth steps. In the first step, elements related to the shape of a material are created on the basis of information related to the shape of the material. In the second step, processing is executed in which the elements related to the shape of the material which were created in the first step are read into areas to be subjected to processing in the third step. In the third step, a tool path is generated for each element read in the second step. In the fourth step, the tool paths generated for each element in the third step are connected.
    Type: Application
    Filed: July 6, 2017
    Publication date: August 1, 2019
    Inventors: Jun ETO, Shinichi TAKEUCHI, Noriaki SUGIHARA
  • Publication number: 20190203412
    Abstract: A wire rope formed from a resin core and six strands, the resin core having an inner core with a circular cross section and an outer layer built up on the periphery thereof. The outer layer has a melting temperature lower than that of the inner core. The six strands are twisted together helically on the periphery of the resin core in an intertwining die in such a state that gaps are assured between the strands. The resulting wire rope is heated in a heating unit at a temperature higher than the melting temperature of the outer layer but lower than the melting temperature of the inner core. The wire rope is formed by subsequently compressing the six strands from the periphery thereof in a compressing die. The molten outer layer is hardened by natural cooling, after which the wire rope is taken up.
    Type: Application
    Filed: March 7, 2019
    Publication date: July 4, 2019
    Applicant: TOKYO ROPE MANUFACTURING CO., LTD.
    Inventors: Shigeki WATANABE, Kaori KANAMORI, Jun TAKEUCHI
  • Patent number: 10323865
    Abstract: A compact cooling system based on thermoelastic effect is provided. In one embodiment, the system comprises a pair of rollers serving as a heat sink, stress applicator and belt drive, a cold reservoir and a solid refrigerant belt coupled to the cold reservoir and to the heat sinks to pump heat from the cold reservoir to the heat sink. The refrigerant belt comprises solid thermoelastic materials capable of thermoelastic effect. The refrigerant material is mechanically compressed when entering the gap of the roller and subsequently released after passing through. When compressed the refrigerant material transforms to martensite phase and releases heat to the roller and neighboring materials. After released by the rollers, the refrigerant material transforms back to austenite and absorbs heat from the ambient atmosphere.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: June 18, 2019
    Inventors: Jun Cui, Ichiro Takeuchi
  • Patent number: 10300060
    Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: May 28, 2019
    Assignee: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Jun Takeuchi, Satoshi Itadani, Kazuya Hashimura, Masahiro Ikura, Masato Higashino, Tetsuya Yasuhiro, Takeshi Nagaura
  • Publication number: 20190135785
    Abstract: A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases
    Type: Application
    Filed: December 31, 2018
    Publication date: May 9, 2019
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Takayuki Inukai, Jun Takeuchi, Tomoko Yasuhiro
  • Patent number: 10208022
    Abstract: A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: February 19, 2019
    Assignee: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Takayuki Inukai, Jun Takeuchi, Tomoko Yasuhiro
  • Patent number: 10208034
    Abstract: A compound represented by general formula (I) and having a quinoline skeleton has a strong Axl inhibitory activity, and therefore the compound can be an agent for treating Axl-related diseases, for example, cancer such as acute myeloid leukemia, chronic myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.
    Type: Grant
    Filed: December 24, 2015
    Date of Patent: February 19, 2019
    Assignee: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Takayuki Inukai, Jun Takeuchi, Tomoko Yasuhiro
  • Publication number: 20190024248
    Abstract: A water electrolysis system is equipped with a water electrolysis device, a water supply passage, a hydrogen supply passage, a gas-liquid separator, a first water drainage passage, a first water drainage valve, a second water drainage valve, a determination unit, and a valve control unit. In a method of stopping operation of the water electrolysis system, in a water drainage step, in the case that the determination unit determines that operation of the water electrolysis device has been stopped, the first water drainage valve is controlled to be placed in a valve open state, thereby draining liquid water from the gas-liquid separator into the first water drainage passage.
    Type: Application
    Filed: July 13, 2018
    Publication date: January 24, 2019
    Inventors: Jun Takeuchi, Daisuke Kurashina, Yukihiro Fukushima
  • Publication number: 20180256573
    Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.
    Type: Application
    Filed: May 9, 2018
    Publication date: September 13, 2018
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Jun TAKEUCHI, Satoshi ITADANI, Kazuya HASHIMURA, Masahiro IKURA, Masato HIGASHINO, Tetsuya YASUHIRO, Takeshi NAGAURA
  • Publication number: 20180258072
    Abstract: A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases
    Type: Application
    Filed: May 10, 2018
    Publication date: September 13, 2018
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Takayuki INUKAI, Jun TAKEUCHI, Tomoko YASUHIRO
  • Patent number: 9993479
    Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: June 12, 2018
    Assignee: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Jun Takeuchi, Satoshi Itadani, Kazuya Hashimura, Masahiro Ikura, Masato Higashino, Tetsuya Yasuhiro, Takeshi Nagaura