Abstract: An exercise suggestion device, an exercise suggestion method and an exercise suggestion program that can suggest an effective exercise are to be provided. An exercise suggestion device includes: an exercise correction unit which corrects exercise information set on the basis of user information about a user and including exercise duration and exercise intensity of an exercise to be carried out by the user, on the basis of dietary information indicating composition of a meal of the user; and a suggestion unit which suggests at least one of the exercise intensity included in the exercise information that is corrected and an exercise type corresponding to the exercise intensity, and the exercise duration included in the exercise information that is corrected.

Abstract: A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases

Abstract: A compound represented by the general formula (1) has a pyridone ring structure introduced into a pyrrolo pyrimidine skeleton, so that the compound has a strong Axl inhibitory activity. Consequently, the compound can be used as a therapeutic agent for Axl-related diseases including cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.

Abstract: A motor function evaluation system includes: a height changing unit (lift mechanism) which changes a relative height dimension between a seat surface where a user sits and a placement surface where the user's soles are placed; a first pressure detection unit which detects a pressure applied by the soles; a movement details reporting unit (reporting unit) which reports details of a motion test that should be carried out by the user; and an evaluation unit which evaluates a motor function of the user on the basis of a detection result by the first pressure detection unit when the motion test is carried out by the user.

Abstract: In a control method of a differential pressure water electrolysis system, a reference water level of a gas-liquid separator for normal operations is set to discharge a liquid water stored in the gas-liquid separator to a discharge tube. A depressurization reference water level which is a lower water level than the reference water level is set to discharge the liquid water stored in the gas-liquid separator to the discharge tube upon depressurizing. A depressurization valve is opened to reduce pressure at a cathode side after operation of a differential pressure water electrolysis device has been stopped, in a state with voltage applied. A permissible water level upper limit value at which an open/close valve is opened is switched from the reference water level to the depressurization reference water level when the depressurization valve is opened.

Abstract: A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.

Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.

Abstract: A high differential pressure water electrolysis system includes a high differential pressure water electrolysis device, a water supply tank, a high pressure gas-liquid separator, a hydrogen outlet line, a drain line, a low pressure gas-liquid separator, a water return line, and a pressure maintaining mechanism. The drain line is to drain a liquid water separated by the high pressure gas-liquid separator. The low pressure gas-liquid separator is disposed in the drain line and has a discharge line via which a gas separated by the low pressure gas-liquid separator is to be discharged. The water return line connects the low pressure gas-liquid separator and the water supply tank. The pressure maintaining mechanism is disposed in the discharge line and configured to maintain a pressure in the low pressure gas-liquid separator to be higher than a pressure in the water supply tank.

Abstract: A biological information detector includes a biological information detector that detects biological information of a user, a storage that stores the biological information, a timepiece that indicates a current date-time, an input unit that receives an input operation, in which when a predetermined input operation is performed on the input unit, the time indicated by the timepiece is stored as an occurrence time of a hypoglycemia symptom.

Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.

Abstract: A water electrolysis system includes a high-pressure hydrogen production unit for electrolyzing water to generate oxygen and high-pressure hydrogen (the pressure of the high-pressure hydrogen being higher than that of the oxygen), and a gas-liquid separation unit for removing water contained in the high-pressure hydrogen. The gas-liquid separation unit is placed on a hydrogen pipe for discharging the high-pressure hydrogen from the high-pressure hydrogen production unit. In addition, the water electrolysis system includes a high-pressure hydrogen supply pipe for transferring dewatered high-pressure hydrogen from the gas-liquid separation unit, a cooling unit, which is placed on the high-pressure hydrogen supply pipe and is capable of variably controlling the temperature of the high-pressure hydrogen to adjust the humidity of the high-pressure hydrogen, and a control unit.

Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.

Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.

Abstract: A compound represented by the general formula (1) has a pyridone ring structure introduced into a pyrrolo pyrimidine skeleton, so that the compound has a strong Axl inhibitory activity. Consequently, the compound can be used as a therapeutic agent for Axl-related diseases including cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.

Abstract: A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.

Abstract: A water electrolysis system includes a water electrolysis apparatus, an electric component, and a casing. The electric component is to operate the water electrolysis apparatus. The casing includes a housing chamber, an electric component chamber, and a buffering chamber. The housing chamber has a first ventilation air inlet to introduce external air into the housing chamber and houses the water electrolysis apparatus. The electric component chamber has a second ventilation air inlet to introduce the external air into the electric component chamber and houses the electric component. The first ventilation air inlet and the second ventilation air inlet are separate from each other. The buffering chamber is in communication with the first ventilation air inlet and the second ventilation air inlet. An air pressure in the buffering chamber is to be maintained at atmospheric pressure.

Abstract: A physical condition presentation apparatus calculates a point corresponding to an item based on a calculation rule set for the item classified to a behavior executed by a user and interlocked to an index indicating a physical condition of the user and the behavior executed within a predetermined period by the user, and presents presented information including at least one of the calculated point and evaluation of the physical condition of the user according to the point.

Abstract: An object of the present invention is to provide a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I): (wherein all symbols represent the same meanings as described in the specification), a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.

Abstract: The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.

Abstract: A high pressure water electrolysis system includes a high pressure water electrolysis device, a hydrogen storage device, a high pressure hydrogen pipe, a branch pipe, a non-return valve, a pressure detector, and a controller. The controller includes a threshold storage device, a threshold determination device, and a solenoid valve opening/closing operation device. The threshold storage device is configured to store a first threshold of a pressure value detected by the pressure detector and a second threshold lower than the first threshold. The threshold determination device is configured to determine whether or not the pressure value detected by the pressure detector has reached the second threshold. The solenoid valve opening/closing operation device is configured to open and close a solenoid valve if it is determined that the pressure value detected by the pressure detector has reached the second threshold.