Abstract: An analysis method for optimizing number and position of screws used in long bone (fracture fixation) surgery, including the following steps. Perform a CT scan on a surgical patient to obtain a medical image to build a long bone 3D model. Analyze an X-ray image to obtain a long bone fracture condition and a bone quality condition. Select a bone plate 3D model from the model database. Import the bone plate 3D model into the long bone 3D model and set an initial fixation position of the bone plate 3D model. Instruct the first artificial intelligence to comprehensively analyze the conditions to automatically select alternative solutions in the model database. Then, use a computer-aided analysis system to analyze the stress distribution of the alternative solutions, and a first preferred solution is obtained through simulating analysis, thereby excluding incorrect or ineffective surgical plans to reduce the analysis time and patient wait time and increasing the surgery success rate.

Abstract: A push-bending forming device for titanium alloy tubes is provided, which includes a die main body, a plurality of filling balls, a differential temperature assembly and a punch. The filling balls are configured to be filled in a tube blank, and are made of a metal material, with a heat-resistance temperature over 500° C. A diameter of the filling ball is less than an inner diameter of the tube blank. The punch includes a first pushing part and a second pushing part. A push-bending forming method using such device is also provided.

Abstract: A memory device includes: a first array of memory cells; a second array of tracking cells, the second array being configured to emulate the first array; a first word line coupled to corresponding ones of the memory cells in a corresponding one of rows of the first array and to the tracking cells; a second word line configured to emulate the first word line; a first adjust circuit coupled to the first word line; a second adjust circuit coupled to the second word line; and an adjust-timing circuit coupled to the second adjust circuit.

Abstract: The present application discloses a pellet flue gas circulation and waste heat utilization process and a system thereof, which relates to the technical field of flue gas treatment. The system includes a grate, a rotary kiln, an annular cooler, and ducts connecting each part. On the basis of not changing the existing process a flue gas circulation unit and intelligent control equipment are arranged additionally in the present application. The process is simple, and not only can ensure the parameter stability of the production system such as temperature, gas flow or gas pressure, but also can make full use of the low and medium temperature flue gas components and the waste heat, so as to achieve net zero waste gas discharging, energy saving and emission reduction.

Abstract: A method and an apparatus for generating and displaying a latent image, a storage medium, and an electronic device are provided.

Abstract: Disclosed are a device and a method for nitrogen and phosphorus removal from aquaculture tail water based on agricultural waste filler, and belongs to the technical field of aquaculture tail water treatment. The device includes a device main body, and a reaction part is arranged in the device main body; a bottom end of the device main body is communicated with an aquaculture tail water storage pool, and a top side wall of the device main body is communicated with an effluent collection pool; and the reaction part comprises agricultural waste filler and denitrifying sludge contained in the device main body, and the agricultural waste filler and the denitrifying sludge are soaked in the aquaculture tail water.

Abstract: A memory device is provided and includes a memory array, first to second latch circuits and a gating circuit. Read and write operations are triggered by first and second edges of an internal clock signal respectively. The first latch circuit generates a first output signal in response to an input signal and a first latch clock signal, a first edge of the first latch clock signal generated based on the first edge of the internal clock signal. The second latch circuit generates a second output signal in response to the first output signal and a second latch clock signal, a first edge of the second latch clock signal being between first and second edges of the first latch clock signal. The gating circuit generates, in response to the second output signal and a gating clock generated, a third output signal to the memory array.

Abstract: In some aspects, the disclosure relates to compositions and methods for modulating (e.g., increasing and/or decreasing) bone mass in a subject. In some aspects, the disclosure provides isolated nucleic acids, and vectors such as rAAV vectors, configured to express transgenes that promote (e.g., increase) or inhibit (e.g., decrease) activity, differentiation, or function of certain types of bone cells, for example osteoblasts, osteoclasts, osteocytes, etc. In some embodiments, the isolated nucleic acids and vectors described by the disclosure are useful for treating disorders and conditions associated with increased bone mass (e.g., osteopetrosis) or decreased bone mass (e.g., osteoporosis).

Abstract: A method for constructing a multistage network includes: deploying a plurality of nodes; constructing the upper network with at least one node of the plurality of nodes; and in response to determining there is an isolated node, determining an intermediate node for the isolated node and adding the isolated node into the upper network or one of the at least one sub-network according to the intermediate node.

Abstract: Aspects of the disclosure relate to compositions and methods for treating spinal muscular atrophy (SMA). The disclosure is based, in part, on isolated nucleic acids and vectors (e.g., viral vectors, such as rAAV vectors) encoding SMN1. In some embodiments, the expression of SMN 1 is driven by a native SMN 1 promoter or a variant thereof. In some embodiments, isolated nucleic acids and vectors of the disclosure have reduced toxicity and/or increased transgene expression relative to previously described SMN-encoding vectors.

Abstract: An error correction code circuit includes a first error correction code circuit configured to generate correction data and a first correction check bit according to received source data and a source check bit corresponding to the received source data, a second error correction code circuit connected to the first error correction code circuit, and configured to, according to the correction data and at least one of the first correction check bit or the source check bit, determine whether the correction data is wrong and generate a second correction check bit, and a comparison circuit connected between the first error correction code circuit and the second error correction code circuit, and configured to compare the first correction check bit with the second correction check bit and determine whether the first correction check bit is wrong.

Abstract: A memory circuit includes a control circuit coupled to the word line driver circuit. The control circuit is configured to delay a leading or falling edge of a word line signal in response to at least a first clock signal. The control circuit includes a first clock circuit configured to generate a second clock signal in response to a first reset signal and a clock signal, and an adjustable delay circuit configured to adjust a delay between the second and third clock signal in response to the second clock signal and an enable signal. The third clock signal is a delayed version of the second clock signal. An amount of the delay between the second and third clock signal is based on a voltage difference between a first supply voltage having a first swing, and a second supply voltage having a second swing.

Abstract: Aspects of the disclosure relate to compositions and methods for treating spinal muscular atrophy (SMA). The disclosure is based, in part, on isolated nucleic acids and vectors (e.g., viral vectors, such as rAAV vectors) encoding SMN1. In some embodiments, the expression of SMN1 is driven by a native SMN1 promoter or a variant thereof. In some embodiments, isolated nucleic acids and vectors of the disclosure have reduced toxicity and/or increased transgene expression relative to previously described SMN-encoding vectors.

Abstract: Provided herein are functionalized monoclonal antibodies (mAbs) including antibody fragments, including those where a Fab-binding molecule (Fab binding moiety) linked to a steric hindering molecule (steric hindering chemical moiety) is mechanically interlocked (e.g., through noncovalent conjugation) with the antibody or antibody fragment. Also provided are compositions that form highly stable and versatile drug delivery and diagnostic compositions.

Abstract: Provided herein are, inter alia, methods of treating cancer using compounds of the invention.

Abstract: A method of preparing lithium nickel manganese cobalt oxide high-nickel single-crystal positive electrode material comprises the following steps: mixing and ball milling nickel cobalt manganese hydroxide with a lithium source, zirconium oxide, tungsten oxide, and sodium carbonate, then performing primary sintering, pulverizing, and then obtaining an lithium nickel manganese cobalt oxide high-nickel single-crystal positive electrode material intermediate, the temperature of the primary sintering being 50-150° C. higher than a normal sintering temperature; and evenly mixing the lithium nickel manganese cobalt oxide high-nickel single-crystal positive electrode material intermediate and a coating agent, and then performing secondary sintering to obtain the lithium nickel manganese cobalt oxide high-nickel single-crystal positive electrode material.

Abstract: The present disclosure relates to the field of rAAV delivery of transgenes. In some aspects, the disclosure relates to RNAi. Provided herein are recombinant adeno-associated virus (rAAV) vectors comprising modified ITRs. In some embodiments, the modified ITRs comprise a sequence encoding a shRNA, miRNA, or AmiRNA.

Abstract: A push-bending forming device for titanium alloy tubes is provided, which includes a die main body, a plurality of filling balls, a differential temperature assembly and a punch. The filling balls are configured to be filled in a tube blank, and are made of a metal material, with a heat-resistance temperature over 500° C. A diameter of the filling ball is less than an inner diameter of the tube blank. The punch includes a first pushing part and a second pushing part. A push-bending forming method using such device is also provided.

Abstract: A method of fabricating magnetoresistive random access memory, including providing a substrate, forming a bottom electrode layer, a magnetic tunnel junction stack, a top electrode layer and a hard mask layer sequentially on the substrate, wherein a material of the top electrode layer is titanium nitride, a material of the hard mask layer is tantalum or tantalum nitride, and a percentage of nitrogen in the titanium nitride gradually decreases from a top surface of top electrode layer to a bottom surface of top electrode layer, and patterning the bottom electrode layer, the magnetic tunnel junction stack, the top electrode layer and the hard mask layer into multiple magnetoresistive random access memory cells.

Abstract: An aerosol generation system is provided, including an aerosol generator, a primary separation assembly, and a secondary separation assembly, the primary separation assembly includes a primary separation chamber and a pair of electrode plates, an inlet of the primary separation chamber is connected to an outlet of the aerosol generator, and a channel is formed between the pair of the electrode plates for aerosol particles to pass through; the secondary separation assembly comprises a secondary separation chamber, and an inlet of the secondary separation chamber is connected to an outlet of the primary separation chamber. The present disclosure achieves the requirements of different standard particle sizes for filter material testing equipment, the output of aerosols with different particle sizes and concentrations can be achieved by adjusting the voltage and length of the electrode plates, or the size and distance of the mechanical separation plate.