Abstract: In one embodiment, an apparatus includes a processing circuit and logic integrated with and/or executable by the processing circuit. The logic is configured to cause the processing circuit to handle Internet Group Membership Protocol (IGMP) messages received from other devices in a network. Also, the logic is configured to cause the processing circuit to create a general query solicit (GQS) message configured to solicit a general query (GQ) from a multicast snooping querier coupled with the apparatus. In another embodiment, a method includes handling, using a switch in a network, IGMP messages received from other devices in the network, and creating, using the switch, a GQS message configured to solicit a GQ from a multicast snooping querier coupled with the switch. Other systems, methods, and computer program products are described in more embodiments.

Abstract: A position locating method and apparatus are applied to the electronic information field, so that shifting an indication cursor in a wide range using a wireless indication device can be avoided, and a user operation can be simplified. The method comprises detecting a line-of-sight orientation of a user, and obtaining a line-of-sight orientation parameter of the user; detecting a line-of-sight source of the user, and obtaining a line-of-sight source position of the user; obtaining a position of a screen, and obtaining a screen position of a line of sight according to the line-of-sight orientation parameter, the position of the screen, and the line-of-sight source position; and receiving an adjustment signal, adjusting, according to the adjustment signal, the position displayed on the screen, and displaying an adjusted position on the screen.

Abstract: A refrigerator (100) includes a liner (10) forming a refrigeration compartment (101); a wine rack (20) having a bottle placing portion (21) and an end being connected to a side wall of the refrigeration compartment (101) and pivoting about an axis in an up-down direction, in which the wine rack is capable of shifting between a first position where the wine rack abuts against to the side wall and a second position where the wine rack is perpendicular to the side wall; and an auxiliary bracket (30) being connected to a rear side wall of the refrigeration compartment (101) and opposite to the bottle placing portion (21). The wine rack of the refrigerator occupies a small space in a refrigeration compartment when not in use.

Abstract: Methods for detection and diagnosis of Sjögren's Syndrome in a subject, determining the stage or progression of Sjögren's Syndrome in a subject, determining the effectiveness of a treatment for Sjögren's Syndrome, and selecting a subject for treatment for Sjögren's Syndrome are disclosed. The methods typically include measuring the level of one or more Sjögren's Syndrome biomarkers in a biological sample obtained from a subject. Biomarkers for Sjögren's Syndrome include, but are not limited to, GADD153 and Del-1.

Abstract: A touch panel having a cover plate, a sensor electrode layer, an insulating layer and a jumper layer is provided. The sensor electrode layer has first axis electrodes, second axis electrodes, bonding pads and first periphery traces. Each first axis electrode has first electrode blocks that are electrically connected to each other. Each second axis electrode has second electrode blocks that are electrically isolated from each other. The bonding pads are disposed on the periphery region of the cover plate. The first periphery traces are electrically connected to the bonding pads and the first axis electrodes or the second axis electrodes respectively. The insulating layer has first via holes and second via holes. The jumper layer has jumper traces and second periphery traces, wherein the second periphery traces are electrically connected to the first axis electrodes or the second axis electrodes through the first via holes.

Abstract: The present invention discloses a method for processing non-unicast routes information in a TRILL network and a corresponding RBridge, wherein the RBridge has a neighbor relation with a plurality of other RBridges in the TRILL network, and the RBridge is the RBridge which computes non-unicast routes information in the neighbor relation, and in the method, the RBridge executes steps of: sending an acknowledgement message to the plurality of other RBridges, wherein the acknowledgement message acknowledges that the RBridge is the RBridge which computes the non-unicast routes information; obtaining a network topology related to the non-unicast routes information in the TRILL network; computing the non-unicast routes information based on the network topology; and distributing the computed non-unicast routes information to the plurality of other RBridges. The method and the corresponding RBridge are capable of reducing consumption of CPU resource of RBridges in the TRILL network.

Abstract: The administration of a compound advantageously efficacious as ROS1 inhibitor and its effect on subjects with cancer includes administering a compound having certain structural components such as a quinoline moiety in the backbone and at least one tertiary amine containing moiety in a side chain as well as heteroatoms, in particular oxygen atoms, present in the backbone and the side chain for treating a subject suffering from a disease such as cancer. The presence of such structural components allows for an advantageous interaction with the ROS1 kinase domain, in particular with the hinge region. The administered compounds represent a highly promising opportunity in particular for patients bearing ROS1-dependent cancer. A method for targeting tumor cells harboring an abnormality in ROS1 gene includes contacting a cell with compounds of the present invention as well as pharmaceutical compositions comprising such compounds.

Abstract: In one embodiment, a system includes a multicast snooping querier configured to send and receive Internet Group Membership Protocol (IGMP) messages, and one or more IGMP switches interconnected to form a network, wherein at least one of the one or more IGMP switches is connected to the multicast snooping querier, wherein the one or more IGMP switches are configured to: handle IGMP messages, and create a general query solicit (GQS) message configured to solicit a general query from the multicast snooping querier, and wherein the multicast snooping querier is configured to send out a general query (GQ) message on all ports in response to receiving the GQS message to solicit port information and group membership information from each of the one or more IGMP switches. In other embodiments, systems, methods and computer program products are described to enable fast recovery of multicast router ports, upon a STP topology change.

Abstract: The present invention provides an optical imaging processing system. The system includes a screen, an incident light source, and at least one optical transmission medium, where the optical transmission medium is disposed in an optical imaging path in which the incident light source is emergent and is projected to the screen; an light incident face of the optical transmission medium faces the incident light source, and an light exiting face of the optical transmission medium faces the screen, where at least one cavity is included between the light incident face and the light exiting face of the optical transmission medium, and a cross-section shape of the cavity is an isosceles trapezoid; and the cavity includes a light transmission area and a light blanking area used for object accommodation, and the optical imaging path bypasses the light blanking area and penetrates through the optical transmission medium through the light transmission area.

Abstract: A mesh WLAN controller (100) operates in mesh soft-access-point or mesh client modes. When operating in the mesh client mode it performs a mesh network scan, for detecting at least one mesh WLAN BSS (202), send mesh client access requests to mesh WLAN BSSs detected, and, if mesh client access is achieved, provide information indicative to the accessed WLAN BSSs of any other mesh WLAN BSS to which mesh client access is achieved, and if mesh client access is not achieved with any of the detected mesh WLAN BSSs, operate in the mesh soft-access-point mode. Upon receiving an instruction to operate in a mesh bridge-client mode, the controller detects messages from any of the mesh WLAN BSSs (204, 206) with mesh client access, and forwards the received mesh WLAN messages within any other of the mesh WLAN BSSs to which mesh client access has been achieved.

Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is nobiletin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.

Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is tangeretin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.

Abstract: Methods, computer program products, and systems are presented. The methods include, for instance: locating, by one or more processor, at least one virtual machine within a virtual network, wherein gratuitous address resolution functionality of the at least one virtual machine is inactive; and providing, by the one or more processor, location information of the at least one virtual machine. In one embodiment, the locating comprises: receiving an IP address of the at least one virtual machine; and selecting a virtual machine hosting network device from a computing network node table, where the computing network node table comprises at least one network connection record of the silent virtual machine network device hosting a silent virtual machine having a known MAC address and an unknown IP address; and querying the silent virtual machine network device for a MAC address corresponding to the IP address of the at least one virtual machine.

Abstract: The invention provides a method of analyzing the methylation status of all or part of an entire genome. Moreover, the invention features methods of and reagents for characterizing biological cells containing DNA that is susceptible to methylation. Such methods include methods of diagnosing cancer, e.g., breast cancer.

Abstract: The present invention provides a compound that inhibits activity of oncogenic ROS1, a composition comprising said compound. The present invention also provides the use of said composition for treating cancer.

Abstract: The present invention provides a compound that inhibits activity of oncogenic ROS1, a composition comprising said compound. The present invention also provides the use of said composition for treating cancer.

Abstract: A compound suitable for treating cancer, in particular NSCLC, inhibits activity of oncogenic ROS1 kinase and ALK kinase. The compound has certain structural components such as a quinoline moiety in the backbone and at least one phenyl-containing moiety in a side chain with a hydrophobic substituent attached to the backbone via an up to 6-membered linking group as well as a further hydrophobic moiety. The presence of the structural components allows for an advantageous interaction with the ROS1 kinase domain and, further, with the ALK kinase domain. Hence, said compound represents a highly promising opportunity for patients bearing ROS1- or ALK-dependent cancer. A composition, in particular a pharmaceutical composition, includes the compound. A method for targeting cancer cells harboring an abnormality in ROS1 gene or ALK gene includes contacting a cell with the compound.

Abstract: The present invention discloses that a method of treating cancer, preferably non-small cell lung cancer, comprises administrating mitoxantrone. The present invention also discloses a method of inhibiting ROS1 kinase comprising administrating mitoxantrone. A pharmaceutical composition comprising mitoxantrone is also disclosed.

Abstract: Methods, computer program products, and network authority devices are presented. The methods include, for instance: updating a source network with migration information of a virtual machine to redirect network traffic for the virtual machine to a destination network; and updating at least one remote network with the migration information of the virtual machine. In one embodiment, the updating includes updating the source network concurrent with a migration of the virtual machine to minimize interruption of the network traffic. In another embodiment, the updating includes updating a network device of the source network to forward the network traffic for the virtual machine to another network device of the destination network. In a further embodiment, the updating includes updating the source network to redirect the network traffic from at least one client on the at least one remote network.

Abstract: The present application discloses a method and a system for detecting malicious code. The method comprises receiving a testing sample; testing the sample with a plurality of malicious code detectors to obtain a plurality of testing results; determining a credibility scale and a reputation value of each of the testing results, wherein the credibility scale indicates whether the testing result is malicious or safe, and the reputation value indicates a quantified trust level corresponding to the credibility scale; and determining a final detection result of the testing sample based on the determined credibility scales and the reputation values of the testing results. According to the technical solution of the present application, the testing results obtained from various malicious code detectors are rationally utilized to improve the testing accuracy for the malicious code.