Abstract: The present invention provides a method for inducing an inversion of normal blood coagulation factor VIII (F8) gene, a method for correcting an inversion of blood coagulation factor VIII gene in which the inversion has occurred, and a Hemophilia A patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the F8 gene, which is responsible for the majority of severe hemophilia A, and thereby may be effectively used for studying the development mechanism of hemophilia A and as a research tool for screening therapeutic agents. The inversion-corrected induced pluripotent stem cell constructed according the method of the present invention enables an efficient and fundamental treatment for hemophilia A by restoring a genotype in which mutation has occurred to a wild type-like state, without limitation via normal gene or protein delivery.

Abstract: The present invention provides a method for inducing an inversion of normal blood coagulation factor VIII (F8) gene, a method for correcting an inversion of blood coagulation factor VIII gene in which the inversion has occurred, and a Hemophilia A patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the F8 gene, which is responsible for the majority of severe hemophilia A, and thereby may be effectively used for studying the development mechanism of hemophilia A and as a research tool for screening therapeutic agents. The inversion-corrected induced pluripotent stem cell constructed according the method of the present invention enables an efficient and fundamental treatment for hemophilia A by restoring a genotype in which mutation has occurred to a wild type-like state, without limitation via normal gene or protein delivery.

Abstract: Disclosed is a carboxylic acid-modified nitrile-based copolymer latex composition, including 0.1-10 parts by weight of a reactive emulsifier based on 100 parts by weight of a monomer mixture, wherein the monomer mixture includes 40-88 wt % of a conjugated diene-based monomer, 10-50 wt % of an ethylenically unsaturated nitrile monomer and 0.1-10 wt % of an ethylenically unsaturated acid monomer. Also disclosed are a method of preparing the carboxylic acid-modified nitrile-based copolymer latex composition and a latex composition for dip molding including the same. The carboxylic acid-modified nitrile-based copolymer latex composition reduces generation of foam through the use of a reactive emulsifier different from the conventional adsorption/desorption type emulsifier, thereby preventing degradation of the quality of latex caused by foam. In addition, the carboxylic acid-modified nitrile-based copolymer latex composition avoids a need for introducing a defoaming agent for removing foam or maturation process.

Abstract: Disclosed are a carboxylic acid-modified nitrile copolymer latex for dip molding comprising a combination of a carboxylic acid-modified nitrile copolymer latex and a carboxylic acid-modified styrene copolymer latex, a latex composition for dip molding comprising the same and a molded article prepared therefrom. Molded articles with superior tensile strength are produced by respectively preparing a carboxylic acid-modified nitrile latex having a low glass transition temperature and an average particle diameter of 90 nm or higher, and a carboxylic acid-modified styrene latex having a glass transition temperature of 80° C. or higher and an average particle diameter less than 90 nm and then mixing the two latexes.

Abstract: Disclosed is a latex composition for dip molding comprising a carboxylic acid-modified nitrile copolymer latex and starch and an article produced therefrom. Advantageously, a dip-molded article having low syneresis, less stickiness and superior tensile strength can be obtained by using the carboxylic acid-modified nitrile latex in conjunction with starch.

Abstract: A wearable terminal may include: a terminal mode determination unit configured to determine any one of a plurality of terminal modes based on a use state of the terminal; an information output unit configured to display navigation information; a layout database configured to store a layout to be displayed on the information output unit, in response to each of the terminal modes; and a control unit configured to extract a layout corresponding to the determined terminal mode from the layout database, construct navigation information according to the extracted layout, and output the navigation information through the information output unit.

Abstract: A method to enhance collaboration by enabling users of a content-sharing platform to identify media items to credit the entities that contributed to the media item. Such a method includes receiving a request for a media item and obtaining credit data associated with the media item. The method further includes providing for presentation the media item and a list of entities contributing to the media item as defined by the credit data and when receiving the request pertaining to an entity from the list, providing for presentation a list of media items that the entity has contributed to.

Abstract: Disclosed is a carboxylic acid-modified nitrile-based copolymer latex composition, including 0.1-10 parts by weight of a reactive emulsifier based on 100 parts by weight of a monomer mixture, wherein the monomer mixture includes 40-88 wt % of a conjugated diene-based monomer, 10-50 wt % of an ethylenically unsaturated nitrile monomer and 0.1-10 wt % of an ethylenically unsaturated acid monomer. Also disclosed are a method of preparing the carboxylic acid-modified nitrile-based copolymer latex composition and a latex composition for dip molding including the same. The carboxylic acid-modified nitrile-based copolymer latex composition reduces generation of foam through the use of a reactive emulsifier different from the conventional adsorption/desorption type emulsifier, thereby preventing degradation of the quality of latex caused by foam. In addition, the carboxylic acid-modified nitrile-based copolymer latex composition avoids a need for introducing a defoaming agent for removing foam or maturation process.

Abstract: Protection against unauthorized copying of digital media content is achieved by receiving information from a client device related to its storing function used to store digital media content that is to be sent to the client device; and performing a procedure to protect against unauthorized copying of the digital media content if the client device is able to store the digital media content using its storing function.

Abstract: Provided are a latex for dip molding, a composition for dip molding, a preparation method of a dip molded product, and a dip molded product prepared thereby. The latex for dip molding includes a conjugated diene monomer, an ethylenically unsaturated nitrile monomer, and an ethylenically unsaturated acid monomer, wherein the latex further includes sodium methallyl sulfonate as a copolymerizable ionic monomer. A dip molded product having excellent tensile strength, elongation, and touch may be obtained from a composition using the latex according to the present invention, and the generation of limitations, such as non-uniformity of physical properties and difficulties in product management, may be prevented.

Abstract: The present invention relates to a composition for preventing or treating renal diseases. The composition of the present invention improves lipid metabolism, prevents histological damage including renal fibrosis, alleviates microalbuminuria, and maintains nephrons of renal glomeruli. Therefore, the composition is useful for treating renal diseases.

Abstract: Disclosed are a latex composition for dip-forming and a dip-formed nitrile glove produced therefrom which comprise nanoparticulate zinc oxide in a latex for dip-forming, thus advantageously exhibiting superior workability during glove production, having excellent wear sensation due to low modulus at 300%, and not readily tearing in spite of small thickness due to high tensile strength. In addition, the latex composition stably maintains a pH in spite of using a small amount of pH adjuster and thus improves glove production process efficiency.

Abstract: An interfacing method for user feedback is disclosed, in which the interfacing method may include determining an expression mode of at least one interface element among a plurality of interface elements based on a relative relationship among cumulative numbers of the interface elements selected from the interface elements corresponding to response paths to contents.

Abstract: The present invention relates to an in-situ method for preparing rebaudioside A from sucrose and stevioside by sucrose synthase and glycosyltransferase.

Abstract: A personalized service method using a user history in a mobile terminal is provided. The personalized service method using the user history in the mobile terminal includes: checking at least one of event information and context information which occurred due to a user; checking a user's location, a user's condition, a user's emotional state, or an event occurrence time when the at least one of event information and context information occur; reflecting the user's location, the user's condition, the user's emotional state, or the event occurrence time in the at least one of event information and context information, and recording the at least one of event information and context information, having reflected the user's location, the user's condition, the user's emotional state, or the event occurrence time, in a database in a diary type; and displaying a representing image corresponding to the at least one of event information and context information, having been recorded in the diary type.

Abstract: A mobile terminal equipped with first and second display modules provided at the front and the rear, respectively, and a method of controlling the mobile terminal, is provided. The method includes displaying a screen image related to a first operating mode on the first display module, if it is determined that the mobile terminal has been rotated on a predetermined axial direction, switching the mobile terminal from the first operating mode to a second operating mode; and displaying a screen image related to the second operating mode on the second display module. Therefore, it is possible to control various operations performed by the mobile terminal upon the motion of the mobile terminal using the first and second display modules.

Abstract: A personalized service method using a user history in a mobile terminal is provided. The personalized service method using the user history in the mobile terminal includes: checking at least one of event information and context information which occurred due to a user; checking a user's location, a user's condition, a user's emotional state, or an event occurrence time when the at least one of event information and context information occur; reflecting the user's location, the user's condition, the user's emotional state, or the event occurrence time in the at least one of event information and context information, and recording the at least one of event information and context information, having reflected the user's location, the user's condition, the user's emotional state, or the event occurrence time, in a database in a diary type; and displaying a representing image corresponding to the at least one of event information and context information, having been recorded in the diary type.

Abstract: A mobile terminal equipped with first and second display modules provided at the front and the rear, respectively, and a method of controlling the mobile terminal, is provided. The method includes displaying a screen image related to a first operating mode on the first display module, if it is determined that the mobile terminal has been rotated on a predetermined axial direction, switching the mobile terminal from the first operating mode to a second operating mode; and displaying a screen image related to the second operating mode on the second display module. Therefore, it is possible to control various operations performed by the mobile terminal upon the motion of the mobile terminal using the first and second display modules.

Abstract: The present invention relates to a carboxylic acid-modified nitrile-based copolymer latex composition and a dip molded article including the same, the composition including: a carboxylic acid-modified nitrile-based copolymer latex having a glass transition temperature of ?30 to ?20° C.; and a bentonite dispersion solution. The dip molded article using the carboxylic acid-modified nitrile-based copolymer latex composition according to the present invention has high tensile strength and excellent wearable sensation, and thus the dip molded article may be usefully applied to dip molded latex articles such as surgical gloves, checkup gloves, a condom, a catheter, industrial gloves, household gloves, or health care articles.