Patents by Inventor Ka Leung

Ka Leung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10183027
    Abstract: The present disclosure relates to theranostic prodrugs with responsive signals in-vitro or in-vivo and uses thereof. It also relates to synthesized europium complexes for evaluating the binding with integrin ?v?3.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: January 22, 2019
    Assignee: Hong Kong Baptist University
    Inventors: Ka Leung Wong, Hongguang Li
  • Patent number: 10137115
    Abstract: This invention provides a nucleus-permeable small-molecule inhibitor, L2P4 (where L2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium chloride and P4 is an amino acid sequence comprising CAhxYFMVFGGRrRK and they were coupled through amide bond) and synthesis thereof, which effectively targets the dimerization interface of EBNA1, a critical process for the growth of EBVs and the associated tumors. The present invention also provides method of treating and imaging EBV-associated cancers.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: November 27, 2018
    Assignee: Hong Kong Baptist University
    Inventors: Ka Leung Wong, Nai Ki Mak, Lijun Jiang
  • Publication number: 20180252652
    Abstract: The present disclosure relates to urinary polyamines useful as prostate cancer biomarkers and a sensitive and specific, method for detecting and quantifying urinary polymaines using lanthanide complexes.
    Type: Application
    Filed: April 16, 2018
    Publication date: September 6, 2018
    Inventor: Ka Leung WONG
  • Publication number: 20180223580
    Abstract: This invention is about an improved garage door opener system, with design features for preventing garage door break-in from outside of the garage using an object such as a hanger. Typically, a person pulls down a cord connected to a release handle to release emergency release of a garage door opener, allowing the door to be manually open or closed. An unauthorized person may attempt to pull down the cord using a hanger from outside the garage or to pull or push down the release handle, to open the door from outside and gain unauthorized entrance. The improved garage door opener system provides a mechanism to reverse the pulling direction of the cord and also protects release handle from being accessed from outside the garage, for increased security.
    Type: Application
    Filed: February 9, 2018
    Publication date: August 9, 2018
    Inventors: Philip Yu Wing TSUI, Gallen Ka Leung TSUI
  • Publication number: 20180172695
    Abstract: The present disclosure relates to urinary polyamines useful as prostate cancer biomarkers. In particular, the present disclosure provides a novel, highly-sensitive and specific, method for detecting and quantifying urinary polyamines using lanthanide complexes or citrate capped gold nanoparticles.
    Type: Application
    Filed: October 16, 2017
    Publication date: June 21, 2018
    Inventor: Ka Leung WONG
  • Publication number: 20180078564
    Abstract: The present disclosure relates to theranostic prodrugs with responsive signals in-vitro or in-vivo and uses thereof. It also relates to synthesized europium complexes for evaluating the binding with integrin ?v?3.
    Type: Application
    Filed: September 20, 2017
    Publication date: March 22, 2018
    Inventors: Ka Leung WONG, Hongguang LI
  • Publication number: 20180057691
    Abstract: The present invention provides photopolymer compositions for 3D printing which have low viscosity, proper curing rate, low volume shrinkage, and low ash content. Such compositions may be used in 3D printing for direct investment casting of products and rapid prototyping.
    Type: Application
    Filed: August 30, 2016
    Publication date: March 1, 2018
    Inventors: Jifan LI, Wai Yan CHAN, Ka Kit YEE, Ka Leung Kevin CHEUK
  • Patent number: 9902860
    Abstract: The present invention provides photopolymer compositions for 3D printing which have low viscosity, proper curing rate, low volume shrinkage, and low ash content. Such compositions may be used in 3D printing for direct investment casting of products and rapid prototyping.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: February 27, 2018
    Assignee: Nano and Advanced Materials Institute Limited
    Inventors: Jifan Li, Wai Yan Chan, Ka Kit Yee, Ka Leung Kevin Cheuk
  • Patent number: 9899003
    Abstract: A display system and a method for displaying items and/or performances is provided. At least a display panel is used to play multimedia content. In an embodiment, at least a portion of the display panel turns transparent for displaying items or performances in a display space. In an embodiment, the display item is moved in accordance with the multimedia played on the display panel. In an embodiment, light effects are adjusted during the display. In an embodiment, audio media is played and adjusted during the display.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: February 20, 2018
    Assignee: SMART SHOWCASE LIMITED
    Inventors: Ka Leung Sin, Jason Felix Tsz-Kiu Chiu
  • Patent number: 9840522
    Abstract: The present invention relates to a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their PDT processes can be monitored via NIR emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin PDT agent (Er—R3) that are capable of killing the bladder tumor cells selectivity via 1O2 from porphyrin moiety and affording the fluorescence imaging simultaneously upon Er—R3 binding with the integrin ?v?3 isoform in bladder cancer cells.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: December 12, 2017
    Assignee: Hong Kong Baptist University
    Inventors: Ka Leung Wong, Wai Kwok Wong
  • Publication number: 20170342090
    Abstract: The present invention relates to a water-soluble, simple, stable tris(N-(tert-butyl)acetamide) cyclen-based europium complex HGEu001 which exhibits the specific subcellular localization in the primary cilium with a quantum yield as high as 10% in water and a lifetime of 0.56 ms lifetime. In particular, the present invention provides simplicity of the design and synthesis of a complex. Comprehensive studies were performed in numerous cell lines, such as HeLa, SN-K-SH and MRC5; the motif structure, HGEu002, has also been synthesized as the negative control for in vitro imaging studies. The two photon in vitro imaging were done in three dimensions to emphasize on the specific localization in primary cilium of HGEu001. This is one of the very limited examples for direct primary cilium imaging.
    Type: Application
    Filed: May 25, 2017
    Publication date: November 30, 2017
    Inventors: Ka Leung WONG, Hongguang LI, Chi Fai CHAN, Rongfeng LAN
  • Patent number: 9813657
    Abstract: A control system and a method that controls a display system are provided. The control system receives sensing signals from one or more sensors and controls the display of items based on the sensing signals received. In an embodiment, the control system controls at least a display panel that plays multimedia content. In an embodiment, the control system controls the movement of items on display in accordance with the multimedia played on the display panel. In an embodiment, the control system controls lighting effects within a display area containing the item on display during the display. In an embodiment, the control system controls audio media that is played during the display.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: November 7, 2017
    Assignee: SMART TLCD LIMITED
    Inventors: Jason Felix Tsz-Kiu Chiu, Ka Leung Sin
  • Publication number: 20170304284
    Abstract: This invention provides a nucleus-permeable small-molecule inhibitor, L2P4 (where L2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium chloride and P4 is an amino acid sequence comprising CAhxYFMVFGGRrRK and they were coupled through amide bond) and synthesis thereof, which effectively targets the dimerization interface of EBNA1, a critical process for the growth of EBVs and the associated tumors. The present invention also provides method of treating and imaging EBV-associated cancers.
    Type: Application
    Filed: April 24, 2017
    Publication date: October 26, 2017
    Inventors: Ka Leung WONG, Nai Ki MAK, Lijun JIANG
  • Publication number: 20170287440
    Abstract: A display system and a method for displaying items and/or performances is provided. At least a display panel is used to play multimedia content. In an embodiment, at least a portion of the display panel turns transparent for displaying items or performances in a display space. In an embodiment, the display item is moved in accordance with the multimedia played on the display panel. In an embodiment, light effects are adjusted during the display. In an embodiment, audio media is played and adjusted during the display.
    Type: Application
    Filed: November 6, 2014
    Publication date: October 5, 2017
    Inventors: Ka Leung Sin, Jason Felix Tsz-Kiu Chiu
  • Publication number: 20170222663
    Abstract: A memory device may include memory components to store data. The memory device may also include a processor that may decode a codeword associated with the data. The processor may receive the codeword and determine whether the codeword is independently decodable using a BCH decoder. The processor may then decode the codeword using the BCH decoder when the codeword is determined to be independently decodable using the BCH decoder. Otherwise, the processor may decode the codeword using a second decoder and the BCH decoder when the codeword is not determined to be independently decodable using the BCH decoder.
    Type: Application
    Filed: April 19, 2017
    Publication date: August 3, 2017
    Inventors: Sivagnanam Parthasarathy, Nicholas Julian Richardson, Patrick Robert Khayat, Mustafa Nazmi Kaynak, Ka Leung Ling, Robert B. Eisenhuth
  • Patent number: 9662528
    Abstract: A torsion bar includes a housing and at least one inner core. The housing has a receiving space, two opposite fixing grooves defined in a sidewall of the housing and communicating with the receiving space, and a plurality of stripes positioned at an outer surface thereof. The inner core is received in the receiving space, and includes two opposite fixing elements corresponding to the fixing grooves. Each of the fixing elements includes a plurality of first protruding portions located at a side end thereof to facilitate a user to disengage from the housing, and a plurality of second protruding portions located at a surface thereof adjacent to the side end to prevent the inner core from disengaging accidently from the housing. A cross-section of the receiving space is similar to a cross-section of the inner core.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: May 30, 2017
    Assignee: GOOD SHINE DEVELOPMENT LTD.
    Inventor: Ka Leung Wong
  • Patent number: 9654144
    Abstract: A memory device may include memory components to store data. The memory device may also include a processor that may decode a codeword associated with the data. The processor may receive the codeword and determine whether the codeword is independently decodable using a BCH decoder. The processor may then decode the codeword using the BCH decoder when the codeword is determined to be independently decodable using the BCH decoder. Otherwise, the processor may decode the codeword using a second decoder and the BCH decoder when the codeword is not determined to be independently decodable using the BCH decoder.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: May 16, 2017
    Assignee: Micron Technology, Inc.
    Inventors: Sivagnanam Parthasarathy, Nicholas Julian Richardson, Patrick Robert Khayat, Mustafa Nazmi Kaynak, Ka Leung Ling, Robert B. Eisenhuth
  • Publication number: 20170107238
    Abstract: The present invention relates to a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their PDT processes can be monitored via NIR emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin PDT agent (Er—R3) that are capable of killing the bladder tumor cells selectivity via 1O2 from porphyrin moiety and affording the fluorescence imaging simultaneously upon Er—R3 binding with the integrin ?v?3 isoform in bladder cancer cells.
    Type: Application
    Filed: November 15, 2016
    Publication date: April 20, 2017
    Inventors: Ka Leung WONG, Wai Kwok WONG
  • Patent number: 9586088
    Abstract: An abdomen exerciser includes a connecting element, a first roller, a second roller and a holding component. The connecting element includes two connectors and two roller bearings, each connector has a receiving groove, a plurality of locating pores and a plurality of limiting slots. The connectors are connected with the first roller and the second roller respectively. The holding component is received in the receiving grooves. The holding component includes a plurality of ball bearings and a plurality of limiting elements, the ball bearings are locked in the locating pores, the limiting elements are received in the limiting slots.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: March 7, 2017
    Assignee: SHENZHEN KANGRUIDE BIOTECHNOLOGY CO., LTD
    Inventor: Ka Leung Wong
  • Patent number: 9522925
    Abstract: The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional—PDT and imaging—gadolinium complex (Gd—N) with a molecular formula of: which can target cancer, cells specifically. The present invention provides a PDT drug that can specifically localize on the anionic cell membrane of cancer cells in which its laser-excited photoemission signal can be monitored without triggering the phototoxic generation of reactive oxygen species—singlet oxygen—prior to due excitation. The present invention also provides the use of Gd—N as a tumor selective PDT photosensitizer modality.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: December 20, 2016
    Assignee: Hong Kong Baptist University
    Inventors: Ka-Leung Wong, Wai-Kwok Wong, Rongfeng Lan, Tao Zhang