Abstract: Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

Abstract: A cooling fan (1) includes a fan housing (10), a stator (20), a rotor (30) and a bearing assembly (40). A tube (111) extends upwardly from a central portion of the fan housing. The stator is mounted around the tube. The bearing assembly includes a ball bearing (333) and a sleeve bearing (335) received in two ends of the tube, respectively. The rotor has a shaft (336) extending into and roratably supported by the bearing assembly. An elastic element (332) is arranged on the ball bearing to provide a pressing force on the ball bearing toward the sleeve bearing. An oil retaining element (339) is arranged around a bottom end of the shaft and spaced from the shaft. The oil retaining element is attached to the sleeve bearing to provide oil for the sleeve bearing.

Abstract: An electrical connector (100) for mating with a mating connector (700) along a mating direction includes an insulative housing (1) defining a passageway and a pair of latching members (2) inserted in the passageway. Each latching member has a resisting portion (21) and a latching portion (22) extending forwardly from the resisting portion and deformable from a first position to a second position for latching with the mating connector. The resisting portion includes an upper section (211) and a lower section formed at opposite sides of the latching portion and respectively abutting against the insulative housing along the mating direction when the latching portion is located in the second position.

Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.

Abstract: A cooling fan includes a fan housing (10) having a shaft seat (16) extending downwardly therefrom, a stator (20) being fixedly mounted around the shaft seat, a shaft (80) with a top end being fixedly connected to the shaft seat and a free end (82) extending downwardly therefrom, a rotor (30) comprising a hub (32) having a plurality of blades (34) extending radially and outwardly, and a sleeve bearing (40). A fixing tube (36) extends upwardly from a center of the hub. The fixing tube has a closed bottom end and defines a fixing hole (360) therein. The sleeve bearing is fixedly received in the fixing hole of the fixing tube to rotate with the rotor. A bearing hole is defined in the sleeve bearing for extension of the free end of the shaft therethrough.

Abstract: An immersion mold for a medical device balloon. The mold has a cavity adapted to receive a hollow parison expandable therein to form the balloon. The cavity has a length, a first end, a second end, and a cavity wall with inner and outer surfaces. The mold form cavity wall is provided with one or a plurality of through-holes along the length thereof to facilitate entrance and egress of a heated fluid.

Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.

Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.

Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Abstract: An immersion mold for a medical device balloon. The mold has a cavity adapted to receive a hollow parison expandable therein to form the balloon. The cavity has a length, a first end, a second end, and a cavity wall with inner and outer surfaces. The mold form cavity wall is provided with one or a plurality of through-holes along the length thereof to facilitate entrance and egress of a heated fluid.

Abstract: This invention provides, among other things, novel compounds useful for treating inflammatory conditions, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Abstract: Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

Abstract: A computer-implemented method is provided to facilitate creation of linked inter-related models in a database. The method comprises obtaining a search text and match criteria from a user, and determining whether a prequery exists. If not, a list of all destination items is obtained. If yes, a determination is made whether the prequery is enabled. If not, a list of all destination items is obtained. If enabled, a list of all destination items limited by the prequery is obtained. A determination is then made whether all match criteria is selected. If yes, all items in the destination list are returned to the user. If not, a word list is generated by parsing all words from the search text. All valid synonyms are added for each word in the word list. The items in the destination list are reduced to items that match at least one word in the word list. A determination is made whether one or more additional filters exist. If not, a reduced list filtered by the match criteria is returned to the user.

Abstract: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Abstract: Disclosed herein are compositions and methods for the identification of a subject at risk for developing microvascular complications associated with diabetes such as diabetic nephropathy and diabetic retinopathy. Also disclosed is a therapeutic target for the prevention and treatment of microvascular complications associated with diabetes.

Abstract: A fan rotor includes a hub (10), a plurality of blades (20) radially disposed around the hub, and a magnet (30) located in an inner side of the hub. The hub includes a top wall (12) and a sidewall (14) surrounding the top wall. A plurality of spaced first ribs (17) is disposed between the top wall of the hub and a top wall of the magnet. A plurality of spaces (171) is formed between adjacent first ribs for accommodating equilibrium clay (50) therein.

Abstract: A cooling fan includes a fan housing (30) having a central tube (34) extending upwardly therefrom; the central tube has a bottom, annular protrusion (31). A bearing (61) is received in the central tube and mounted on the protrusion. A stator (20) is mounted around the central tube. A rotor (10) includes a shaft (18) having a free end (186) extending through the bearing and defining a notch (184) therein. A locking washer (63) engages into the notch of the shaft to limit movement of the shaft along an axial direction thereof. A balance structure (62) is arranged between the locking washer and the bearing. The balance structure is made of magnet and exerts a downwardly pulling force on the shaft to prevent the rotor from moving upwardly when the rotor is rotated.

Abstract: A cable connector assembly (100) includes an insulative housing (22) having a plurality of contacts received therein, a cable assembly (3) connected with the contacts by a printed circuit board (5), an upper shielding member (11) and a lower shielding member (12) together with the upper shielding member to form a receiving space (10). Each of the upper shielding member and the lower shielding member have a base portion (111, 121) and a plurality of vertical walls (113, 114, 115, 123, 124, 125) extending from the base portion. The lower shielding member (12) defines a stopping portion (126) to prevent the upper shielding member (11) from moving along a transverse direction. The stopping portion (126) is of U-shaped and comprises a first restricting flake (1261) and a second restricting flake (1262), and a corresponding vertical wall (113) of the upper shielding member is located between the first restricting flake (1261) and the second restricting flake (1262).

Abstract: A cooling fan includes a fan housing (10) having a central tube (11) extending upwardly therefrom, a bearing (20) received in the central tube, a stator (40) mounted around the central tube, a rotor (30) having a shaft (37) extending into the bearing, and a magnetic ring (38) being fixedly mounted to the rotor to rotate with the rotor during operation of the cooling fan. The bearing is made of iron-copper alloy. The magnetic ring is made of hard magnetic material and exerts a magnetic attraction on the bearing, whereby the rotor is pulled downwardly by a magnetic attraction of the bearing on the magnetic ring to lessen the floating problem of the rotor during operation of the cooling fan.