Patents by Inventor Kang Zhang

Kang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7264458
    Abstract: Medical device balloons are formed from a tubular parison by a process or apparatus which establishes a controlled location (initiation zone) on the parison where radial expansion is initiated. Initiation within the initiation zone is achieved by heating the parison in that location to a higher temperature than the remainder of the parison for at least a portion of the blowing time. A variety of apparatus configurations are provided, some of which allow for the size and location of the initiation zone to be readily reconfigured. Balloons can also be modified, post-blowing, using heating apparatus and methods described.
    Type: Grant
    Filed: January 7, 2004
    Date of Patent: September 4, 2007
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Thomas J. Holman, Nam H. Hoang, Jeffrey S. Lindquist, Richard Dunn, Scott Schewe, Kevin Silberg, David Parsons, Ken Xiao Kang Zhang, Afsar Ali
  • Publication number: 20070155699
    Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
    Type: Application
    Filed: August 16, 2006
    Publication date: July 5, 2007
    Applicant: Anacor Pharmaceuticals
    Inventors: Stephen Baker, Tsutomu Akama, Michael Alley, Steven Benkovic, Michael DiPierro, Vincent Hernandez, Karin Hold, Isaac Kennedy, Igor Likhotvorik, Weimin Mao, Kirk Maples, Jacob Plattner, Fernando Rock, Virginia Sanders, Aaron Stemphoski, George Yiannikouros, Siead Zegar, Yong-Kang Zhang, Huchen Zhou
  • Patent number: 7217278
    Abstract: Medical balloons and balloon preforms are made by methods which include the step of selectively removing material from the proximal and/or distal ends of a segment. In the case of a thermoplastic material characterized by one or more glass transition temperatures, the segment may optionally be maintained at a temperature below the glass transition temperature of the segment during the material removal step.
    Type: Grant
    Filed: February 13, 2001
    Date of Patent: May 15, 2007
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Daniel Keith Tomaschko, Daniel James Horn, Xiao Kang Zhang, Nao Pao Lee
  • Patent number: 7179620
    Abstract: The gene responsible for Stargardt-like macular dystrophy has been identified, along with its normal allelic form. The mutant gene encodes a mutant protein containing a frameshift mutation, resulting in abnormal fatty acid synthesis and transport in the retina. Also disclosed are assays for Stargardt-like macular dystrophy and therapies.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: February 20, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Konstantin Petrukhin, Wen Li, Kang Zhang
  • Publication number: 20060246048
    Abstract: The gene responsible for Stargardt-like macular dystrophy has been identified, along with its normal allelic form. The mutant gene encodes a mutant protein containing a frameshift mutation, resulting in abnormal fatty acid synthesis and transport in the retina. Also disclosed are assays for Stargardt-like macular dystrophy and therapies.
    Type: Application
    Filed: June 28, 2006
    Publication date: November 2, 2006
    Inventors: Konstantin Petrukhin, Wen Li, Kang Zhang
  • Publication number: 20060234981
    Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
    Type: Application
    Filed: February 16, 2006
    Publication date: October 19, 2006
    Applicant: Anacor Pharmaceuticals
    Inventors: Stephen Baker, Tsutomu Akama, Carolyn Bellinger-Kawahara, Vincent Hernandez, Karin Hold, James Leyden, Kirk Maples, Jacob Plattner, Virginia Sanders, Yong-Kang Zhang
  • Patent number: 7091005
    Abstract: The gene responsible for Stargardt-like macular dystrophy has been identified, along with its normal allelic form. The mutant gene encodes a mutant protein containing a frameshift mutation, resulting in abnormal fatty acid synthesis and transport in the retina. Also disclosed are assays for Stargardt-like macular dystrophy and therapies.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: August 15, 2006
    Assignee: Merck & Co., Inc.
    Inventors: Konstantin Petrukhin, Wen Li, Kang Zhang
  • Publication number: 20060178356
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: March 22, 2006
    Publication date: August 10, 2006
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Publication number: 20050142155
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: February 10, 2005
    Publication date: June 30, 2005
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Del Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Publication number: 20050124691
    Abstract: Disclosed are novel ?-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Application
    Filed: March 5, 2004
    Publication date: June 9, 2005
    Inventors: Judith Kelleher, Kirk Maples, Alina Dykman, Yong-Kang Zhang, Allan Wilcox, Julian Levell
  • Publication number: 20050113416
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: December 16, 2004
    Publication date: May 26, 2005
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Del Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Publication number: 20050070503
    Abstract: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
    Type: Application
    Filed: June 14, 2004
    Publication date: March 31, 2005
    Inventors: Ving Lee, Stephen Benkovic, Stephen Baker, Kirk Maples, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio Sauro, Chetan Pandit, Zhuoyi Su, Zhixiang Yang
  • Publication number: 20050054644
    Abstract: Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
    Type: Application
    Filed: June 15, 2004
    Publication date: March 10, 2005
    Inventors: Ving Lee, Jacob Plattner, Stephen Benkovic, Stephen Baker, Kirk Maples, Carolyn Bellinger-Kawahara, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio Sauro
  • Patent number: 6863861
    Abstract: A balloon blowing process which involves radial expansion of an extruded tubing segment which has been subjected to a stretching step prior to radial expansion, the process utilizing an internal pressure and a temperature which together cause at least a portion of the tubing to expand to an interior diameter (ID) which is greater than the interior diameter of the extruded segment prior to extrusion.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: March 8, 2005
    Assignee: Boston Scientific SciMed, Inc.
    Inventors: Xiao Kang Zhang (Ken), Daniel Horn, Nao Pao Lee, Victor Leo Schoenle
  • Publication number: 20040098019
    Abstract: Medical balloons and balloon preforms are made by methods which include the step of selectively removing material from the proximal and/or distal ends of a segment. In the case of a thermoplastic material characterized by one or more glass transition temperatures, the segment may optionally be maintained at a temperature below the glass transition temperature of the segment during the material removal step.
    Type: Application
    Filed: August 5, 2003
    Publication date: May 20, 2004
    Inventors: Daniel K. Tomaschko, Daniel J. Horn, Xiao Kang Zhang, Nao Pao Lee
  • Publication number: 20040067226
    Abstract: The gene responsible for Stargardt-like macular dystrophy has been identified, along with its normal allelic form. The mutant gene encodes a mutant protein containing a frameshift mutation, resulting in abnormal fatty acid synthesis and transport in the retina. Also disclosed are assays for Stargardt-like macular dystrophy and therapies.
    Type: Application
    Filed: October 3, 2003
    Publication date: April 8, 2004
    Inventors: Konstantin Petrukhin, Wen Li, Kang Zhang
  • Publication number: 20030087957
    Abstract: Disclosed are novel &agr;-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Application
    Filed: February 11, 2002
    Publication date: May 8, 2003
    Inventors: Judith A. Kelleher, Kirk R. Maples, Alina Dykman, Yong-Kang Zhang, Allan L. Wilcox, Julian Levell
  • Publication number: 20030073712
    Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
    Type: Application
    Filed: July 23, 2002
    Publication date: April 17, 2003
    Inventors: Bing Wang, Yong-Kang Zhang, Jian Chen, Wei Zhang, Jiangao Song, Ughetta Del Balzo, Lesley Brown, Sekhar Boddupalli, Steven Bobzin, Sylvain Gilat, Guy Miller
  • Patent number: 6441032
    Abstract: Disclosed are novel &agr;-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: August 27, 2002
    Assignee: Centaur Pharmaceuticals, Inc.
    Inventors: Judith A. Kelleher, Kirk R. Maples, Alina Dykman, Yong-Kang Zhang, Allan L. Wilcox, Julian Levell
  • Patent number: 6433008
    Abstract: Disclosed are novel aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: August 13, 2002
    Assignee: Centaur Pharmaceuticals, Inc.
    Inventors: Judith A. Kelleher, Kirk R. Maples, Alina Dykman, Yong-Kang Zhang, Allan L. Wilcox, Julian Levell