Abstract: A sales management server system is for management of online store sale of an application to run at an edge server connected to one or more edge devices. The sales management server system includes an app database storing the application, a management controller, and a distribution controller. The distribution controller includes: a purchase request transmitting unit that transmits purchase request information to a communicably connected developer terminal about the application for which a purchase request has been given via a communicably connected user terminal; and a result transmitting unit that transmits distribution authorization. information to the user terminal if availability information received from the developer terminal responsive to the purchase request includes an indication of being purchasable.

Abstract: An application sales management server system that assists B2B online processing related to sales and distribution of applications while making use of a conventional business practice related to B2B is provided. A sales management server system operating in an edge server communicably connected to one or more edge devices is communicably connected to a terminal of an intermediary dealer that relays sales of applications and a terminal of an end user who uses the edge device and the edge server via a communication unit. A control unit includes: an ordering processing unit that notifies the terminal of a serial number corresponding to an application on the basis of an application purchase request from the terminal of the intermediary dealer; and a distribution processing unit that distributes an application corresponding to a serial number to the edge server in response to receiving the serial number transmitted from the terminal of the end user.

Abstract: An application sales management server system that assists B2B online processing related to sales and distribution of applications while making use of a conventional business practice related to B2B is provided. A sales management server system operating in an edge server communicably connected to one or more edge devices is communicably connected to a terminal of an intermediary dealer that relays sales of applications and a terminal of an end user who uses the edge device and the edge server via a communication unit. A control unit includes: an ordering processing unit that notifies the terminal of a serial number corresponding to an application on the basis of an application purchase request from the terminal of the intermediary dealer; and a distribution processing unit that distributes an application corresponding to a serial number to the edge server in response to receiving the serial number transmitted from the terminal of the end user.

Abstract: An application sales management server system that assists B2B online processing related to sales and distribution of applications while making use of a conventional business practice related to B2B is provided. A sales management server system operating in an edge server communicably connected to one or more edge devices is communicably connected to a terminal of an intermediary dealer that relays sales of applications and a terminal of an end user who uses the edge device and the edge server via a communication unit. A control unit includes: an ordering processing unit that notifies the terminal of a serial number corresponding to an application on the basis of an application purchase request from the terminal of the intermediary dealer; and a distribution processing unit that distributes an application corresponding to a serial number to the edge server in response to receiving the serial number transmitted from the terminal of the end user.

Abstract: Provided is a tissue regeneration construct having a good engraftment property and capable of promoting a stable and favorable regeneration to a target site, the tissue regeneration construct being a member to be applied to a target site for transplantation and regeneration to regenerate tissue, including a transplant body, and an engraftment layer arranged overlapping at least a part of an outer surface of the transplant body, wherein: the transplant body includes a support, cells for regenerating the tissue that are arranged at least either one of a space between the supports and a space formed by a pore inside the support, and a base material for retaining the cells; the base material of the engraftment layer is gelatinous; and the engraftment layer is a layer in which the support does not exist.

Abstract: An application sales management server system that assists B2B online processing related to sales and distribution of applications while making use of a conventional business practice related to B2B is provided. A sales management server system operating in an edge server communicably connected to one or more edge devices is communicably connected to a terminal of an intermediary dealer that relays sales of applications and a terminal of an end user who uses the edge device and the edge server via a communication unit. A control unit includes: an ordering processing unit that notifies the terminal of a serial number corresponding to an application on the basis of an application purchase request from the terminal of the intermediary dealer; and a distribution processing unit that distributes an application corresponding to a serial number to the edge server in response to receiving the serial number transmitted from the terminal of the end user.

Abstract: A sales management server system is communicably connected to a terminal of an intermediary dealer that relays sales of applications and a terminal of an end user who uses an edge device and an edge server via a communication unit. A control unit includes: an ordering processing unit that notifies of a serial number on the basis of an application purchase request from the terminal of the intermediary dealer; and a distribution processing unit that distributes a license that includes information on the number of edge devices per one license and controls the number of edge devices connected by the application together with an application correlated with the serial number to the edge server upon receiving the serial number from the terminal of the end user.

Abstract: An application sales management server system capable of designating an application purchaser while making use of a conventional business practice related to B2B is provided. A sales management server system that manages sales of applications operated by an edge server communicably connected to one or more edge devices is communicably connected to a terminal via a communication unit. A control unit includes: a browsing information providing unit that provides application product information in response to a browse request from the terminal; and a mall processing unit that correlates a predetermined user with an application group including one or more pre-selected applications. The browsing information providing unit provides application product information of the application group in response to the browse request only when the user is correlated with the application group including the one or more pre-selected applications.

Abstract: There is provided a method for manufacturing a porous material including a calcium carbonate, the method including a digestion carbonation process of causing digestion and carbonation of a porous material including a calcium oxide in a presence of water under a flow of a gas including carbon dioxide.

Abstract: A method of fabricating a scaffold for tissue engineering that includes a frame structure including one of poly-D-lactic acid and poly-L-lactic acid and a coating layer formed on a surface of the frame structure and including a lactic acid-glycolic acid copolymer. The method includes mixing a first granular porous substance including one of poly-D-lactic acid and poly-L-lactic acid with a second granular porous substance including the lactic acid-glycolic acid copolymer to prepare a mixture, and pressurizing and heating the mixture in a mold. In the heating, the mixture is heated to a temperature greater than or equal to the melting point of the lactic acid-glycolic acid copolymer and less than the melting point of one of poly-D-lactic acid and poly-L-lactic acid.

Abstract: A method of fabricating a scaffold for tissue engineering that includes a frame structure including one of poly-D-lactic acid and poly-L-lactic acid and a coating layer formed on a surface of the frame structure and including a lactic acid-glycolic acid copolymer. The method includes mixing a first granular porous substance including one of poly-D-lactic acid and poly-L-lactic acid with a second granular porous substance including the lactic acid-glycolic acid copolymer to prepare a mixture, and pressurizing and heating the mixture in a mold. In the heating, the mixture is heated to a temperature greater than or equal to the melting point of the lactic acid-glycolic acid copolymer and less than the melting point of one of poly-D-lactic acid and poly-L-lactic acid.

Abstract: A method of fabricating a scaffold for tissue engineering that includes a frame structure including one of poly-D-lactic acid and poly-L-lactic acid and a coating layer formed on a surface of the frame structure and including a lactic acid-glycolic acid copolymer. The method includes mixing a first granular porous substance including one of poly-D-lactic acid and poly-L-lactic acid with a second granular porous substance including the lactic acid-glycolic acid copolymer to prepare a mixture, and pressurizing and heating the mixture in a mold. In the heating, the mixture is heated to a temperature greater than or equal to the melting point of the lactic acid-glycolic acid copolymer and less than the melting point of one of poly-D-lactic acid and poly-L-lactic acid.

Abstract: A scaffold for tissue engineering includes a frame structure including one of poly-D-lactic acid and poly-L-lactic acid, and a coating layer formed on a surface of the frame structure and including a lactic acid-glycolic acid copolymer.

Abstract: It is a problem of the present invention to provide a convenient and safe periodontal tissue regeneration material and provide a method of regenerating a periodontal tissue. The present invention provides a periodontal tissue regeneration material comprising dedifferentiated fat cells (DFAT) as the convenient and safe periodontal tissue regeneration material. The present invention provides a method of regenerating a periodontal tissue with the periodontal tissue regeneration material.

Abstract: To provide a bone tissue regeneration sheet having a cortical bone tissue layer of 200 ?m or more in thickness, the bone tissue regeneration sheet is produced by seeding chondroblast or stem cells for differentiating to chondrocyte on one side of a porous bioabsorbable polymer sheet, taking the seeded porous body into a culture medium, applying centrifugal force of 100 to 1000 G to the culture medium for a predetermined time so as to aggregate the chondroblast or the stem cells for differentiating to chondrocyte, culturing the aggregated cells in a culture medium not containing serum but containing one or two or more kinds selected from ascorbic acid, an ascorbic acid derivative, and dexamethasone without applying centrifugal force to form a chondrocyte layer having a thickness of 200 ?m or more.

Abstract: Provided is a tissue regeneration construct having a good engraftment property and capable of promoting a stable and favorable regeneration to a target site, the tissue regeneration construct being a member to be applied to a target site for transplantation and regeneration to regenerate tissue, including a transplant body, and an engraftment layer arranged overlapping at least a part of an outer surface of the transplant body, wherein: the transplant body includes a support, cells for regenerating the tissue that are arranged at least either one of a space between the supports and a space formed by a pore inside the support, and a base material for retaining the cells; the base material of the engraftment layer is gelatinous; and the engraftment layer is a layer in which the support does not exist.

Abstract: Provided is a fracture treatment device enabling efficient bone regeneration. The fracture treatment device (10) for connecting a bone on one side of a fracture site and a bone on the other side of the fracture site, the device including a fixation member (11) having a stick shape, a tissue regeneration structure (15) disposed in a manner to cover at least a part of the fixation member, wherein the tissue regeneration structure includes a support body made of a bioabsorbable material and cells retained in the support body, which cells regenerate bone.

Abstract: Provided is a treatment method which enables regeneration of bone tissue even when the size of a damaged site of bone is large. The treatment method comprises the steps of: culturing chondrocytes which have been seeded onto a porous body, or differentiating stem cells having chondrogenic differentiation potential which have been seeded onto a porous body into chondrocytes and culturing the chondrocytes; and implanting the porous body having the cultured chondrocytes.

Abstract: Method for regeneration of mesenchymal tissue from mesenchymal cells on a porous sheet composed of bioabsorbable polymer material.

Abstract: For easily seeding cells in its scaffold, a porous cell scaffold is produced by steps of filling a guiding solution with kinematic viscosity being 50 to 450% of that of a culture medium, in a whole continuous small hole structure having hole diameters of 5 to 3200 ?m and an average hole diameter of 50 to 1500 ?m, of a sheet-shaped or block-shaped scaffold having a thickness of 2 mm or more, supplying thereafter a culture medium with cells being suspended to an upper side of the scaffold, sucking the guiding solution from a lower side of the scaffold by low suction force, and entering thereby the culture medium with cells being suspended into the whole small hole structure, where a water absorber such as a filter paper is preferably used for sucking the guiding solution by low suction force.