Patents by Inventor Kawin Setsompop

Kawin Setsompop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11874353
    Abstract: Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are recursively designed to have a flat magnitude and phase profile across a slice for a range of different flip angles by accounting for longitudinal magnetization remaining after each preceding RF pulse is applied.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: January 16, 2024
    Assignee: The General Hospital Corporation
    Inventors: Avery J. L. Berman, Jonathan R. Polimeni, William A. Grissom, Kawin Setsompop, Thomas Witzel
  • Publication number: 20230358836
    Abstract: Lipid suppression in magnetic resonance imaging (“MRI”) is provided on a slice-by-slice basis using tailored local field control that is configured for lipid control for each slice in a planned slice prescription. Only those lipid voxels that fall within the bandwidth of the concurrent RF excitation pulse are targeted. Switched B0 offset fields are used to improve lipid suppression pulse performance by pushing water and lipids apart in the frequency domain. Multi-coil B0 shim arrays with rapidly switchable output currents that can be turned on during the lipid suppression pulse may be used. A convex optimization may be used to jointly solve for the shim currents and the lipid suppression pulse center frequency and bandwidth to optimize lipid suppression while minimizing water signal loss.
    Type: Application
    Filed: May 5, 2023
    Publication date: November 9, 2023
    Inventors: Kawin Setsompop, Jinmin Xu, Jason Stockmann
  • Patent number: 11486953
    Abstract: Techniques are disclosed related to the compensation of phase variations introduced into k-space lines, which cause imaging artifacts. The techniques utilize the detection of motion via an encoding plus motion model, which does not require the use of additional prospective or retrospective motion detection techniques. The techniques described herein use the encoding plus motion model to reconstruct an initial image from a set of motion states, and then calculate phase information from images that are projected form the initial reconstructed image using a projection onto convex sets (POCS). The phase information is incorporated into the encoding plus motion model over several iterations to minimize data consistency error, thereby generating a refined image that compensates for patient motion over the set of motion states.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: November 1, 2022
    Assignees: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Polak, Kawin Setsompop, Stephen Farman Cauley
  • Patent number: 11391803
    Abstract: Systems and methods are provided for improving MRI data acquisition efficiency while providing more detailed information with high resolution and isotropic resolution without gaps. Improved data acquisition efficiency may be achieved by implementing a machine learning algorithm with a hardware processor and a memory to estimate imperfections in fast imaging sequences, such as a multi-shot echo planar imaging (MS-EPI) sequence. These imperfections, such as patient motion, physiological noise, and phase variations, may be difficult to model or otherwise estimate using standard physics-based reconstructions.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: July 19, 2022
    Assignee: The General Hospital Corporation
    Inventors: Berkin Bilgic, Sohyun Han, Stephen F. Cauley, Lawrence L. Wald, Kawin Setsompop
  • Publication number: 20220221540
    Abstract: Magnetic resonance imaging (“MRI”) using a PROPELLER echo-planar time-resolved imaging with dynamic encoding (“PEPTIDE”) scheme is described. The PEPTIDE scheme combines a PROPELLER-style trajectory with an echo-planar time-resolved imaging (“EPTI”) acquisition framework, along with dynamic-updating of sensitivity-encoding information.
    Type: Application
    Filed: March 26, 2020
    Publication date: July 14, 2022
    Inventors: Merlin John Casper Fair, Kawin Setsompop
  • Patent number: 11360176
    Abstract: A method includes determining an initial magnetic resonance imaging, MRI, dataset (201) in image domain based on an initial reconstruction of MRI measurement data obtained using an undersampling scheme (400); and determining patches (231-233) of the initial MRI dataset (201) in accordance with a patching scheme, the patching scheme depending on the undersampling scheme (400); and, for each one of the patches (231-233): applying a machine-learned algorithm to obtain a respective patch (231-233) of a reconstructed MRI dataset, the machine-learned algorithm depending on the undersampling scheme (400); and combining the patches (231-233) of the reconstructed MRI dataset.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: June 14, 2022
    Assignees: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Polak, Kawin Setsompop
  • Publication number: 20220179024
    Abstract: Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are recursively designed to have a flat magnitude and phase profile across a slice for a range of different flip angles by accounting for longitudinal magnetization remaining after each preceding RF pulse is applied.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 9, 2022
    Inventors: Avery J.L. Berman, Jonathan R. Polimeni, William A. Grissom, Kawin Setsompop, Thomas Witzel
  • Publication number: 20220065971
    Abstract: Techniques are disclosed related to the compensation of phase variations introduced into k-space lines, which cause imaging artifacts. The techniques utilize the detection of motion via an encoding plus motion model, which does not require the use of additional prospective or retrospective motion detection techniques. The techniques described herein use the encoding plus motion model to reconstruct an initial image from a set of motion states, and then calculate phase information from images that are projected form the initial reconstructed image using a projection onto convex sets (POCS). The phase information is incorporated into the encoding plus motion model over several iterations to minimize data consistency error, thereby generating a refined image that compensates for patient motion over the set of motion states.
    Type: Application
    Filed: September 2, 2021
    Publication date: March 3, 2022
    Applicants: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Polak, Kawin Setsompop, Stephen Farman Cauley
  • Patent number: 11249162
    Abstract: Techniques are disclosed related to the compensation of phase offsets introduced into k-space lines as a result of encoding of blip gradients due when motion is present, which may be used for parallel magnetic resonance imaging (MRI) techniques such as blipped SMS or blipped CAIPIRINHA. The compensation of these additional phase offsets may prevent artifacts that would otherwise be present in the reconstructed images as a result of motion during the MRI scanning procedure. The additional phase offsets may be accounted for during the image acquisition phase of the MRI scan or, alternatively, during the image reconstruction phase.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: February 15, 2022
    Assignees: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Nicolas Splitthoff, Daniel Polak, Kawin Setsompop, Borjan Gagoski
  • Publication number: 20220043089
    Abstract: Techniques are disclosed related to the compensation of phase offsets introduced into k-space lines as a result of encoding of blip gradients due when motion is present, which may be used for parallel magnetic resonance imaging (MRI) techniques such as blipped SMS or blipped CAIPIRINHA. The compensation of these additional phase offsets may prevent artifacts that would otherwise be present in the reconstructed images as a result of motion during the MRI scanning procedure. The additional phase offsets may be accounted for during the image acquisition phase of the MRI scan or, alternatively, during the image reconstruction phase.
    Type: Application
    Filed: August 4, 2020
    Publication date: February 10, 2022
    Applicants: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Nicolas Splitthoff, Daniel Polak, Kawin Setsompop, Borjan Gagoski
  • Publication number: 20210373105
    Abstract: In a method and system for reducing motion artifacts in magnetic resonance image data, a scout scan of the region of the patient is performed, a magnetic resonance (MR) measurement of the region of the patient is performed to acquire MR image data of the region of the patient, and motion correction is performed on the acquired MR image data based on the scout scan to generate corrected MR image data. The motion correction technique advantageously reduces an influence of a patient motion on the magnetic resonance image data.
    Type: Application
    Filed: April 23, 2021
    Publication date: December 2, 2021
    Applicants: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Polak, Stephen Farman Cauley, Kawin Setsompop
  • Publication number: 20210364589
    Abstract: Systems and methods are provided for improving MRI data acquisition efficiency while providing more detailed information with high resolution and isotropic resolution without gaps. Improved data acquisition efficiency may be achieved by implementing a machine learning algorithm with a hardware processor and a memory to estimate imperfections in fast imaging sequences, such as a multi-shot echo planar imaging (MS-EPI) sequence. These imperfections, such as patient motion, physiological noise, and phase variations, may be difficult to model or otherwise estimate using standard physics-based reconstructions.
    Type: Application
    Filed: March 4, 2019
    Publication date: November 25, 2021
    Inventors: Berkin Bilgic, Sohyun Han, Stephen F. Cauley, Lawrence L. Wald, Kawin Setsompop
  • Patent number: 11181598
    Abstract: A computer-implemented method for reconstructing a MRI image, including: receiving a plurality of MRI measurement data sets ƒ1 to ƒN, wherein each data set is acquired from an examination object based on a different MRI protocol of an MRI system; receiving MRI images u10 to uN0 corresponding to the MRI measurement data sets ƒ1 to ƒN; applying, in at least a first step GD1, trained functions to the MRI images u10 to uN0, using a neural network and a forward-sampling operator, wherein at least one output MRI image uT is generated; and providing the at least one output MRI image uT, wherein the forward-sampling operator determines an agreement between at least one MRI image u10 to uN0 and the corresponding MRI measurement data set ƒ1 to ƒN.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 23, 2021
    Assignees: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Polak, Kawin Setsompop
  • Publication number: 20210264645
    Abstract: A method for reconstructing a MRI image may include: receiving MRI measurement data sets f1 to fN, each data set being acquired from an examination object based on a different MRI protocol of an MRI system; receiving MRI images u10 to uN0 corresponding to the MRI measurement data sets f1 to fN; performing one or more translation and rotation transformations on the MRI images u10 to uN0; applying one or more trained functions: to the transformed MRI images u10 to uN0, using a neural network, and to the MRI images u10 to uN0, using a forward-sampling operator; performing one or more inverse translation and rotation transformations on an output of the neural network; and generating at least one output MRI image uT based on an output of the forward-sampling operator, the inversely transformed output of the neural network, and the input MRI images u10 to uN0.
    Type: Application
    Filed: February 19, 2021
    Publication date: August 26, 2021
    Applicants: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Polak, Kawin Setsompop
  • Patent number: 11035920
    Abstract: Described here are systems and methods for producing images of a subject using magnetic resonance imaging (“MRI”) in which data are acquired using a sparse approximate encoding scheme for controlled aliasing techniques. As one example, the sparse approximate encoding can be used for a Wave-CAIPI encoding scheme, which can enable faster image reconstruction using fewer computational resources, in addition to reducing noise in the reconstructed images relative to those reconstructed from data acquired using a Wave-CAIPI encoding scheme without sparse approximate encoding.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: June 15, 2021
    Assignee: The General Hospital Corporation
    Inventors: Lawrence Wald, Kawin Setsompop, Stephen Cauley
  • Patent number: 11022665
    Abstract: Systems and methods for magnetic resonance imaging (“MRI”) that address the geometric distortions and blurring common to conventional echo planar imaging (“EPI”) sequences, and that provide new temporal signal evolution information across the EPI readout, are described. Echo planar time-resolved imaging (“EPTI”) schemes are described to implement an accelerated sampling of a hybrid space spanned by the phase encoding dimension and the temporal dimension. In general, each EPTI shot covers a segment of this hybrid space using a zigzag trajectory with an interleaved acceleration in the phase-encoding direction. The hybrid space may be undersampled and a tilted reconstruction kernel used to synthesize additional data samples.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: June 1, 2021
    Assignee: The General Hospital Corporation
    Inventors: Kawin Setsompop, Lawrence L. Wald, Fuyixue Wang
  • Patent number: 11009575
    Abstract: Methods for reducing scan time in magnetic resonance imaging (“MRI”), particularly when imaging three-dimensional image volumes, using a simultaneous time-interleaved multislice (“STIMS”) acquisition are described. The unused time in each repetition time (“TR”) period is exploited to provide an additional reduction in encoding time for a three-dimensional acquisition (e.g., a 3D whole brain coverage). Groups of spatially interleaved slices are excited in a single TR, with the excitation and acquisition of the groups of slices being interleaved in time.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: May 18, 2021
    Assignee: The General Hospital Corporation
    Inventors: Berkin Bilgic, Kawin Setsompop, Daniel Polak, Huihui Ye, Lawrence Wald
  • Patent number: 10908248
    Abstract: Systems and methods for simultaneously acquiring high-resolution images of a subject from multiple different slice locations using magnetic resonance imaging (“MRI”) are described. The present invention overcomes the aforementioned drawbacks by providing method for producing a plurality of images of a subject with a magnetic resonance imaging (“MRI”) system. A radio frequency (RF) excitation field is applied by the MRI system to a portion of a subject that includes a plurality of slice locations. First data are simultaneously acquired from each of the plurality of slice locations by the MRI system.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: February 2, 2021
    Assignee: The General Hospital Corporation
    Inventors: Kawin Setsompop, Berkin Bilgic, Lawrence L. Wald, Thomas Witzel
  • Patent number: 10901061
    Abstract: Systems and methods for accelerated diffusion-weighted magnetic resonance imaging using a tilted reconstruction kernel to synthesize unsampled k-space data in phase encoded and point spread function (“PSF”) encoded k-space data are provided. Images reconstructed from the data have reduced B0-related distortions and reduced T2* blurring. In general, data are acquired with systematically optimized undersampling of the PSF and phase encoding subspace. Parallel imaging reconstruction is implemented with a B0 inhomogeneity informed approach to achieve greater than twenty-fold acceleration of the PSF encoding dimension. A tilted reconstruction kernel is used to exploit the correlations in the phase encoding-PSF encoding subspace. Self-navigated phase corrections are computed from the acquired data and used to synthesize the unsampled k-space data.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: January 26, 2021
    Assignee: The General Hospital Corporation
    Inventors: Kawin Setsompop, Lawrence L. Wald, Zijing Dong, Hua Guo, Fuyixue Wang, Timothy G. Reese
  • Patent number: 10895622
    Abstract: Techniques are disclosed to leverage the use of neural networks or similar machine learning algorithms to de-noise highly accelerated Wave-CAIPIRINHA scans. The described techniques facilitate the generation of 3D sequences using a greatly reduced scan time, with the resulting images having a high spatial resolution and an improved SNR compared to conventional approaches.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: January 19, 2021
    Assignees: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Daniel Polak, Esther Raithel, Kawin Setsompop