Patents by Inventor Kazuhiko Fujisawa
Kazuhiko Fujisawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8921449Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: January 21, 2013Date of Patent: December 30, 2014Assignees: Johnson & Johnson Vision Care Inc., Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
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Publication number: 20140296554Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: June 10, 2014Publication date: October 2, 2014Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
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Publication number: 20140296368Abstract: The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas.Type: ApplicationFiled: June 11, 2014Publication date: October 2, 2014Inventors: Ryuta Tamiya, Kazuhiko Fujisawa, Masataka Nakamura
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Publication number: 20140285765Abstract: A medical device includes a layer made of an acidic polymer and a basic polymer formed on at least a part of a surface of a water-containing base material, wherein at least one kind of an acidic polymer and a basic polymer forming the acidic polymer or the basic polymer is a polymer having a hydroxy group.Type: ApplicationFiled: August 14, 2012Publication date: September 25, 2014Applicant: Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Rumiko Kitagawa, Masataka Nakamura
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Publication number: 20140240660Abstract: A medical device includes a layer made of an acidic polymer and a basic polymer formed on at least a part of a surface of a base material, wherein at least one kind of an acidic polymer and a basic polymer forming the layers made of the acidic polymer and the basic polymer is a multi-component copolymer of three or more components.Type: ApplicationFiled: August 14, 2012Publication date: August 28, 2014Applicant: Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Rumiko Kitagawa, Masataka Nakamura
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Publication number: 20140235782Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.Type: ApplicationFiled: April 29, 2014Publication date: August 21, 2014Applicant: Johnson & Johnson Vision Care, Inc.Inventors: Kazuhiko Fujisawa, Masataka Nakamura
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Publication number: 20140198295Abstract: To provide a medical device which is excellent in wettability and lubricity and is also scarcely broken since it is soft, by a medical device in which a layer made of an acidic polymer and a basic polymer is formed on at least a part of a surface of a low water content soft base material, the low water content soft base material containing, as a main component, a copolymer containing a monofunctional monomer component M having one polymerizable functional group and one silicone moiety per molecule.Type: ApplicationFiled: August 10, 2012Publication date: July 17, 2014Applicant: Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Rumiko Kitagawa, Masataka Nakamura
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Patent number: 8779178Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: January 21, 2013Date of Patent: July 15, 2014Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Yokota Yokota, Douglas G. Vanderlaan
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Patent number: 8748548Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.Type: GrantFiled: December 22, 2010Date of Patent: June 10, 2014Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Kazuhiko Fujisawa, Masataka Nakamura
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Publication number: 20140128564Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: November 7, 2012Publication date: May 8, 2014Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota
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Publication number: 20140120146Abstract: A medical antimicrobial composition includes a siloxanyl structure-containing polymer and an ammonium group-containing polymer, which is excellent in transparency, flexibility and mechanical properties, and also excellent in adhesion to a base resin with good mechanical properties, particularly to a silicone resin. The medical antimicrobial composition includes an ammonium group-containing polymer compound (A) dispersed in a siloxanyl structure-containing polymer (B) and a medical device comprising the medical antimicrobial composition.Type: ApplicationFiled: January 3, 2014Publication date: May 1, 2014Applicant: Toray Industries, Inc.Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Tsutomu Goshima
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Patent number: 8710167Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.Type: GrantFiled: May 31, 2013Date of Patent: April 29, 2014Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Thomas L. Maggio, Michelle Carman-Turnage, Kazuhiko Fujisawa, Masataka Nakamura
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Patent number: 8652499Abstract: A medical antimicrobial composition includes a siloxanyl structure-containing polymer and an ammonium group-containing polymer, which is excellent in transparency, flexibility and mechanical properties, and also excellent in adhesion to a base resin with good mechanical properties, particularly to a silicone resin. The medical antimicrobial composition includes an ammonium group-containing polymer compound dispersed in a siloxanyl structure-containing polymer and a medical device comprising the medical antimicrobial composition.Type: GrantFiled: March 5, 2009Date of Patent: February 18, 2014Assignee: Toray Industries, Inc.Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Tsutomu Goshima
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Patent number: 8637589Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: December 7, 2010Date of Patent: January 28, 2014Assignees: Johnson & Johnson Vision Care, Inc., Toray IndustriesInventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
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Patent number: 8623934Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.Type: GrantFiled: February 27, 2013Date of Patent: January 7, 2014Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Thomas L. Maggio, Michelle Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
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Publication number: 20130260066Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.Type: ApplicationFiled: May 31, 2013Publication date: October 3, 2013Inventors: Thomas L. Maggio, Michelle Carman-Turnage, Kazuhiko Fujisawa, Masataka Nakamura
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Patent number: 8541483Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.Type: GrantFiled: February 27, 2013Date of Patent: September 24, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Thomas L. Maggio, Michell Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
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Patent number: 8476389Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.Type: GrantFiled: March 15, 2011Date of Patent: July 2, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Thomas L. Maggio, Michelle Carman Turnage, Kazuhiko Fujisawa, Masataka Nakamura
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Patent number: 8415405Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.Type: GrantFiled: March 15, 2011Date of Patent: April 9, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Thomas L. Maggio, Michelle Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
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Patent number: 8399539Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: November 19, 2011Date of Patent: March 19, 2013Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura