Patents by Inventor Kazuhiko Fujisawa

Kazuhiko Fujisawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140296368
    Abstract: The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas.
    Type: Application
    Filed: June 11, 2014
    Publication date: October 2, 2014
    Inventors: Ryuta Tamiya, Kazuhiko Fujisawa, Masataka Nakamura
  • Publication number: 20140296554
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: June 10, 2014
    Publication date: October 2, 2014
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
  • Publication number: 20140285765
    Abstract: A medical device includes a layer made of an acidic polymer and a basic polymer formed on at least a part of a surface of a water-containing base material, wherein at least one kind of an acidic polymer and a basic polymer forming the acidic polymer or the basic polymer is a polymer having a hydroxy group.
    Type: Application
    Filed: August 14, 2012
    Publication date: September 25, 2014
    Applicant: Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Rumiko Kitagawa, Masataka Nakamura
  • Publication number: 20140240660
    Abstract: A medical device includes a layer made of an acidic polymer and a basic polymer formed on at least a part of a surface of a base material, wherein at least one kind of an acidic polymer and a basic polymer forming the layers made of the acidic polymer and the basic polymer is a multi-component copolymer of three or more components.
    Type: Application
    Filed: August 14, 2012
    Publication date: August 28, 2014
    Applicant: Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Rumiko Kitagawa, Masataka Nakamura
  • Publication number: 20140235782
    Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.
    Type: Application
    Filed: April 29, 2014
    Publication date: August 21, 2014
    Applicant: Johnson & Johnson Vision Care, Inc.
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura
  • Publication number: 20140198295
    Abstract: To provide a medical device which is excellent in wettability and lubricity and is also scarcely broken since it is soft, by a medical device in which a layer made of an acidic polymer and a basic polymer is formed on at least a part of a surface of a low water content soft base material, the low water content soft base material containing, as a main component, a copolymer containing a monofunctional monomer component M having one polymerizable functional group and one silicone moiety per molecule.
    Type: Application
    Filed: August 10, 2012
    Publication date: July 17, 2014
    Applicant: Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Rumiko Kitagawa, Masataka Nakamura
  • Patent number: 8779178
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: January 21, 2013
    Date of Patent: July 15, 2014
    Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Yokota Yokota, Douglas G. Vanderlaan
  • Patent number: 8748548
    Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: June 10, 2014
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura
  • Publication number: 20140128564
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 7, 2012
    Publication date: May 8, 2014
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota
  • Publication number: 20140120146
    Abstract: A medical antimicrobial composition includes a siloxanyl structure-containing polymer and an ammonium group-containing polymer, which is excellent in transparency, flexibility and mechanical properties, and also excellent in adhesion to a base resin with good mechanical properties, particularly to a silicone resin. The medical antimicrobial composition includes an ammonium group-containing polymer compound (A) dispersed in a siloxanyl structure-containing polymer (B) and a medical device comprising the medical antimicrobial composition.
    Type: Application
    Filed: January 3, 2014
    Publication date: May 1, 2014
    Applicant: Toray Industries, Inc.
    Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Tsutomu Goshima
  • Patent number: 8710167
    Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: April 29, 2014
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Thomas L. Maggio, Michelle Carman-Turnage, Kazuhiko Fujisawa, Masataka Nakamura
  • Patent number: 8652499
    Abstract: A medical antimicrobial composition includes a siloxanyl structure-containing polymer and an ammonium group-containing polymer, which is excellent in transparency, flexibility and mechanical properties, and also excellent in adhesion to a base resin with good mechanical properties, particularly to a silicone resin. The medical antimicrobial composition includes an ammonium group-containing polymer compound dispersed in a siloxanyl structure-containing polymer and a medical device comprising the medical antimicrobial composition.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: February 18, 2014
    Assignee: Toray Industries, Inc.
    Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Tsutomu Goshima
  • Patent number: 8637589
    Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: January 28, 2014
    Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Patent number: 8623934
    Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: January 7, 2014
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Thomas L. Maggio, Michelle Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
  • Publication number: 20130260066
    Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.
    Type: Application
    Filed: May 31, 2013
    Publication date: October 3, 2013
    Inventors: Thomas L. Maggio, Michelle Carman-Turnage, Kazuhiko Fujisawa, Masataka Nakamura
  • Patent number: 8541483
    Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: September 24, 2013
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Thomas L. Maggio, Michell Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
  • Patent number: 8476389
    Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: July 2, 2013
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Thomas L. Maggio, Michelle Carman Turnage, Kazuhiko Fujisawa, Masataka Nakamura
  • Patent number: 8415405
    Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: April 9, 2013
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Thomas L. Maggio, Michelle Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
  • Patent number: 8399539
    Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: November 19, 2011
    Date of Patent: March 19, 2013
    Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Patent number: 8357818
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: January 22, 2013
    Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan