Abstract: A therapeutic or prophylactic agent for radiation damage associated with radiation exposure, comprising an eosinophil-removing agent as an active ingredient and the like are provided as a technique for efficiently treating or preventing radiation damage associated with radiation exposure. According to the therapeutic or prophylactic agent comprising an eosinophil-removing agent according to the present invention, by suppressing migration and/or infiltration into target tissue and/or proliferation in the tissue of eosinophils and/or inhibiting the activity or function of the eosinophils, pathological conditions such as inflammatory responses and fibrosis of tissue can be suppressed to effectively treat or prevent radiation damage. Moreover, effective radiation therapy can be performed by suppressing radiation damage.

Abstract: An air-conditioning apparatus includes a controller configured to operate in a heating normal operation mode and a heating-defrosting operation mode. In a case of switching from the heating normal operation mode to the heating-defrosting operation mode, the controller makes a selection from an initial control mode 1, in which control is performed such that an initial frequency of the compressor is set to a predetermined maximum frequency and an initial opening degree of the flow control device is set to an opening degree lower than a predetermined maximum opening degree, and an initial control mode 2, in which control is performed such that the initial opening degree of the flow control device is set to the predetermined maximum opening degree and the initial frequency of the compressor is set to a frequency lower than the predetermined maximum frequency, to execute the heating-defrosting operation mode.

Abstract: An air-conditioning apparatus includes a controller configured to operate in a heating normal operation mode and a heating-defrosting operation mode. In a case of switching from the heating normal operation mode to the heating-defrosting operation mode, the controller makes a selection from an initial control mode 1, in which control is performed such that an initial frequency of the compressor is set to a predetermined maximum frequency and an initial opening degree of the flow control device is set to an opening degree lower than a predetermined maximum opening degree, and an initial control mode 2, in which control is performed such that the initial opening degree of the flow control device is set to the predetermined maximum opening degree and the initial frequency of the compressor is set to a frequency lower than the predetermined maximum frequency, to execute the heating-defrosting operation mode.

Abstract: A therapeutic or prophylactic agent for radiation damage associated with radiation exposure, comprising an eosinophil-removing agent as an active ingredient and the like are provided as a technique for efficiently treating or preventing radiation damage associated with radiation exposure. According to the therapeutic or prophylactic agent comprising an eosinophil-removing agent according to the present invention, by suppressing migration and/or infiltration into target tissue and/or proliferation in the tissue of eosinophils and/or inhibiting the activity or function of the eosinophils, pathological conditions such as inflammatory responses and fibrosis of tissue can be suppressed to effectively treat or prevent radiation damage. Moreover, effective radiation therapy can be performed by suppressing radiation damage.

Abstract: A therapeutic or prophylactic agent for radiation damage associated with radiation exposure, comprising an eosinophil-removing agent as an active ingredient and the like are provided as a technique for efficiently treating or preventing radiation damage associated with radiation exposure. According to the therapeutic or prophylactic agent comprising an eosinophil-removing agent according to the present invention, by suppressing migration and/or infiltration into target tissue and/or proliferation in the tissue of eosinophils and/or inhibiting the activity or function of the eosinophils, pathological conditions such as inflammatory responses and fibrosis of tissue can be suppressed to effectively treat or prevent radiation damage. Moreover, effective radiation therapy can be performed by suppressing radiation damage.

Abstract: An air-conditioning apparatus enables a user to recognize both a leakage of refrigerant and an abnormal condition when a refrigerant leakage condition and the abnormal condition have occurred. When a condition in which a leakage of refrigerant is detected and a condition in which an abnormality is detected have occurred together, the refrigerant leakage condition and the abnormal condition are displayed together on a display part. Consequently, when the condition in which the leakage of refrigerant is detected and the condition in which the abnormality is detected have occurred, the user is allowed to recognize the leakage of refrigerant and the abnormal condition at once.

Abstract: An air-conditioning apparatus is able to ensure an appropriate flow rate of refrigerant and an appropriate amount of oil returned to a compressor that match operation conditions regardless of an operating state of a refrigerant circuit and a change in an operation condition. The air-conditioning apparatus includes: a first detector configured to detect a refrigerant temperature within an accumulator; a storage unit configured to store information regarding a two-layer separation temperature of refrigerant and refrigerating machine oil; a determiner configured to compare the refrigerant temperature with the two-layer separation temperature and determine a two-layer separation state of the refrigerant and the refrigerating machine oil; a second detector configured to detect a state of the refrigerant sucked by the compressor; and a control unit configured to adjust an opening degree of a flow control valve on the basis of the two-layer separation state and a state of the sucked refrigerant.

Abstract: A therapeutic or prophylactic agent for radiation damage associated with radiation exposure, comprising an eosinophil-removing agent as an active ingredient and the like are provided as a technique for efficiently treating or preventing radiation damage associated with radiation exposure. According to the therapeutic or prophylactic agent comprising an eosinophil-removing agent according to the present invention, by suppressing migration and/or infiltration into target tissue and/or proliferation in the tissue of eosinophils and/or inhibiting the activity or function of the eosinophils, pathological conditions such as inflammatory responses and fibrosis of tissue can be suppressed to effectively treat or prevent radiation damage. Moreover, effective radiation therapy can be performed by suppressing radiation damage.

Abstract: An air-conditioning apparatus enables a user to recognize both a leakage of refrigerant and an abnormal condition when a refrigerant leakage condition and the abnormal condition have occurred. When a condition in which a leakage of refrigerant is detected and a condition in which an abnormality is detected have occurred together, the refrigerant leakage condition and the abnormal condition are displayed together on a display part. Consequently, when the condition in which the leakage of refrigerant is detected and the condition in which the abnormality is detected have occurred, the user is allowed to recognize the leakage of refrigerant and the abnormal condition at once.

Abstract: An OCT motion contrast data analysis apparatus includes: a processor; and memory storing computer readable instructions, when executed by the processor, causing the OCT motion contrast data analysis apparatus to execute: acquiring OCT motion contrast data of a subject by an optical coherence tomography; and performing an analysis process with respect to the OCT motion contrast data based on an analysis chart set on image data different from the OCT motion contrast data.

Abstract: An OCT motion contrast data analysis apparatus includes: a processor; and memory storing computer readable instructions, when executed by the processor, causing the OCT motion contrast data analysis apparatus to execute: acquiring OCT motion contrast data of a subject by an optical coherence tomography; and performing an analysis process with respect to the OCT motion contrast data based on an analysis chart set on image data different from the OCT motion contrast data.

Abstract: An OCT motion contrast data analysis apparatus includes: a processor; and memory storing computer readable instructions, when executed by the processor, causing the OCT motion contrast data analysis apparatus to execute: acquiring OCT motion contrast data of a subject by an optical coherence tomography; and performing an analysis process with respect to the OCT motion contrast data based on an analysis chart set on image data different from the OCT motion contrast data.

Abstract: There is provided a repeated type organ fixing instrument having a plurality of suturing tools. The organ fixing instrument includes a rod-shaped engaging portion, a suture fixed to the engaging portion, a puncture needle for housing a plurality of the engaging portions. A plurality of the engaging portions are extruded one by one from the puncture needle by the operation of a operation unit main body. The suture fixed to at least one of the plurality of engaging portions is inserted within the inside of the puncture needle and wherein the other suture is derived from the inside to the outside of the puncture needle.

Abstract: A method of manufacturing an air-conditioning apparatus serving as a refrigeration cycle apparatus includes: performing an operation test in a factory under a state in which inert gas (nitrogen) is sealed into respective devices mounted on an outdoor unit (such as a compressor and a four-way valve) and an outdoor pipe connecting the devices in place of refrigerant having flammability; and shipping the air-conditioning apparatus under the state in which the inert gas remains sealed.

Abstract: There is provided an anti-human CRTH2 antibody which has desired activity by recognizing and binding to a specific human CRTH2; the antibody fragment; DNA which encodes the amino acid sequence of the antibody; a vector which comprises the DNA; hybridomas and antibody producing cells which produce the antibody; a method of producing the antibody; a composition which comprises the antibody or the antibody fragment; a treatment method and a diagnostic method of an allergic disease, an autoimmune disease, a disease accompanied by at least one of increase and hyperergasia of eosinophils; a disease accompanied by at least one of increase and hyperergasia of Th2 cells using the antibody or the antibody fragment; and a medicine and a diagnostic agent which comprise the antibody or the antibody fragment.

Abstract: An air-conditioning apparatus includes a refrigerant circuit in which a compressor, a flow switching device, an outdoor heat exchanger, an expansion device, and an indoor heat exchanger are connected by pipes and through which refrigerant flows, and a control device controlling an operation of the refrigerant circuit to perform switching between a heating operation and a defrosting operation. The control device includes a determination unit that determines, based on operation information regarding the refrigerant circuit, during the heating operation, whether to change a requirement for starting the defrosting operation, a changing unit that changes the requirement for starting the defrosting operation in accordance with a result of determination by the determination unit, and a switching unit that, when the requirement for starting the defrosting operation is satisfied, causes the flow switching device to perform switching to start the defrosting operation.

Abstract: A refrigeration cycle apparatus includes a refrigerant circuit connecting a compressor, a heat source-side heat exchanger, an expansion device, and a use-side heat exchanger to each other by connecting pipes, an outside air temperature sensor configured to detect an outside air temperature, and a controller configured to operate the refrigeration cycle apparatus and to switch between a normal operation mode for controlling the refrigerant circuit based on an operation load of the use-side heat exchanger and a refrigerant amount determining mode for determining whether or not an amount of refrigerant in the refrigerant circuit is appropriate. The controller is configured to switch the normal operation mode to the refrigerant amount determining mode when the outside air temperature detected by the outside air temperature sensor is within a set temperature range.

Abstract: There is provided an anti-human CRTH2 antibody which has desired activity by recognizing and binding to a specific human CRTH2; the antibody fragment; DNA which encodes the amino acid sequence of the antibody; a vector which comprises the DNA; hybridomas and antibody producing cells which produce the antibody; a method of producing the antibody; a composition which comprises the antibody or the antibody fragment; a treatment method and a diagnostic method of an allergic disease, an autoimmune disease, a disease accompanied by at least one of increase and hyperergasia of eosinophils; a disease accompanied by at least one of increase and hyperergasia of Th2 cells using the antibody or the antibody fragment; and a medicine and a diagnostic agent which comprise the antibody or the antibody fragment.

Abstract: There is provided an anti-human CRTH2 antibody which has desired activity by recognizing and binding to a specific human CRTH2; the antibody fragment; DNA which encodes the amino acid sequence of the antibody; a vector which comprises the DNA; hybridomas and antibody producing cells which produce the antibody; a method of producing the antibody; a composition which comprises the antibody or the antibody fragment; a treatment method and a diagnostic method of an allergic disease, an autoimmune disease, a disease accompanied by at least one of increase and hyperergasia of eosinophils; a disease accompanied by at least one of increase and hyperergasia of Th2 cells using the antibody or the antibody fragment; and a medicine and a diagnostic agent which comprise the antibody or the antibody fragment.

Abstract: There is provided an anti-human CRTH2 antibody which has desired activity by recognizing and binding to a specific human CRTH2; the antibody fragment; DNA which encodes the amino acid sequence of the antibody; a vector which comprises the DNA; hybridomas and antibody producing cells which produce the antibody; a method of producing the antibody; a composition which comprises the antibody or the antibody fragment; a treatment method and a diagnostic method of an allergic disease, an autoimmune disease, a disease accompanied by at least one of increase and hyperergasia of eosinophils; a disease accompanied by at least one of increase and hyperergasia of Th2 cells using the antibody or the antibody fragment; and a medicine and a diagnostic agent which comprise the antibody or the antibody fragment.