Patents by Inventor Kazuo Yamashita

Kazuo Yamashita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240159738
    Abstract: A new medical technique using follicular T cells is provided. The present disclosure is based on the finding of public TfhTCR which is specific to disease factors common to various patients, and provides a method for producing follicular T cells specific to a disease, including a step of identifying a disease-related factor or a part thereof having the ability to induce a follicular T cell reactive with the disease-related factor, a step of inducing the follicular T cell specific to the disease, by using the disease-related factor or a part thereof, and a step of obtaining the follicular T cell specific to the disease.
    Type: Application
    Filed: March 15, 2022
    Publication date: May 16, 2024
    Applicants: OSAKA UNIVERSITY, KOTAI Biotechnologies, Inc.
    Inventors: Sho Yamasaki, Xiuyuan Lu, Yuki Hosono, Shigenari Ishizuka, Kazuo Yamashita, Nicolas Claude Paul Sax
  • Publication number: 20240052309
    Abstract: [Problems] To provide a method for producing regenerated T cells via iPS cells into which TCRs isolated from tumor tissue-infiltrating CD106-positive T cells have been introduced. [Solutions] Provided is a method for producing regenerated T cells via iPS cells, comprising: 1. A step for preparing cDNAs respectively encoding a TCR ? chain and a TCR ? chain from individual cells in a CD106-positive T cell population obtained from subjects and having reactivity with a tumor-related antigen; 2. A step for reprogramming peripheral blood mononuclear cells which are obtained from the subjects and from which B cells and T cells have been removed or T cells into iPS cells, and selecting iPS cell clones having high efficiency of differentiation into T cells from the obtained iPS cells; 3.
    Type: Application
    Filed: December 29, 2021
    Publication date: February 15, 2024
    Inventors: Shin Kaneko, Ryosuke Gonotsubo, Mitsujiro Osawa, Yasumichi Hitoshi, Kazuo Yamashita, Nicolas Claude Paul Sax
  • Patent number: 11613307
    Abstract: In a vehicle contact avoidance assist system (1) for providing assistance in avoiding an obstacle located ahead of a vehicle including a contact avoidance control unit (15) configured to perform an obstacle avoidance operation upon detecting an obstacle located ahead of the vehicle, the obstacle avoidance operation including a steering of the steerable wheel via the steering actuator so as to avoid the obstacle, the contact avoidance control unit is configured to apply a restriction on the obstacle avoidance operation depending on a detected gripping state detected by a steering wheel gripping state detection unit (8).
    Type: Grant
    Filed: October 13, 2020
    Date of Patent: March 28, 2023
    Assignee: Honda Motor Co., Ltd.
    Inventor: Kazuo Yamashita
  • Publication number: 20220257656
    Abstract: The present disclosure provides a specific marker for identifying T cells specifically attacking cancer cells and the utilization of the marker. According to the present disclosure, a marker that has a high specificity for identifying T cells specifically attacking cancer cells is provided. According to the present disclosure, treatment or prevention of cancer in a subject with the use of a cell subpopulation contained in a tumor tissue infiltrating CD106+ T cell population or cells expressing a T cell receptor (TCR) expressed thereby can be provided. According to another embodiment of the present disclosure, a method for producing a cellular medicine can be provided. According to the present disclosure, further, a method that comprises using the amount of a cell subpopulation as an index of the responsiveness of a subject to a cancer immunotherapy can be provided. According to the present disclosure, furthermore, a method for acquiring a tumor specific TCR sequence can be provided.
    Type: Application
    Filed: July 9, 2020
    Publication date: August 18, 2022
    Inventors: Yosuke Togashi, Hiroyoshi Nishikawa, Kazuo Yamashita, Nicolas Claude Paul Sax
  • Patent number: 11183852
    Abstract: A control unit repeats the series of processing of comparing a first phase representing a phase of the first reference sine wave and being a phase included in the first synchronization signal, with a second phase that is the phase of the second reference sine wave when the first synchronization signal is received when the communication unit receives the first synchronization signal from the other inverter generator, changing a phase change amount per unit time of the second reference sine wave in accordance with the comparison result, continuing to update the phase of the second reference sine wave so that the phase of the second reference sine wave changes with a phase change amount per unit time after the change with reference to the first phase until the next first synchronizing signal is received from the other inverter generator.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: November 23, 2021
    Assignee: SHINDENGEN ELECTRIC MANUFACTURING CO., LTD.
    Inventors: Kazuo Yamashita, Yasukazu Yamaguchi
  • Publication number: 20210175819
    Abstract: A control unit repeats the series of processing of comparing a first phase representing a phase of the first reference sine wave and being a phase included in the first synchronization signal, with a second phase that is the phase of the second reference sine wave when the first synchronization signal is received when the communication unit receives the first synchronization signal from the other inverter generator, changing a phase change amount per unit time of the second reference sine wave in accordance with the comparison result, continuing to update the phase of the second reference sine wave so that the phase of the second reference sine wave changes with a phase change amount per unit time after the change with reference to the first phase until the next first synchronizing signal is received from the other inverter generator.
    Type: Application
    Filed: December 12, 2017
    Publication date: June 10, 2021
    Applicant: SHINDENGEN ELECTRIC MANUFACTURING CO., LTD.
    Inventors: Kazuo YAMASHITA, Yasukazu YAMAGUCHI
  • Publication number: 20210114660
    Abstract: In a vehicle contact avoidance assist system (1) for providing assistance in avoiding an obstacle located ahead of a vehicle including a contact avoidance control unit (15) configured to perform an obstacle avoidance operation upon detecting an obstacle located ahead of the vehicle, the obstacle avoidance operation including a steering of the steerable wheel via the steering actuator so as to avoid the obstacle, the contact avoidance control unit is configured to apply a restriction on the obstacle avoidance operation depending on a detected gripping state detected by a steering wheel gripping state detection unit (8).
    Type: Application
    Filed: October 13, 2020
    Publication date: April 22, 2021
    Inventor: Kazuo YAMASHITA
  • Publication number: 20210012858
    Abstract: The present invention provides a method for classifying immunological entities. The inventors assume that there are commonalities among antigen specificities for which, without a function being specified in advance, bound immunological entities (antigens, epitopes, etc.) are normally handled individually as separate “functions (for example, whether antigen A has the specificity),” and the inventors have discovered that it is possible to classify immunological entities by evaluating the similarities thereof. This method has a high degree of precision with respect to immunity-related illnesses, and the present invention is clinically applicable.
    Type: Application
    Filed: March 15, 2019
    Publication date: January 14, 2021
    Inventors: Kazuo Yamashita, Joel Billaud, Nicolas Claude Paul Sax
  • Patent number: 10417290
    Abstract: A detailed information providing server includes: an acquisition unit configured to acquire search log information in which a search query is associated with link destination information of a search result obtained by a search using the search query; and a storage unit configured to determine whether or not a keyword corresponding to the search query is included in a news article available on the Internet, and store detailed information in association with the news article into an associated information DB when determining that the keyword is included, the detailed information being acquired by making access according to the link destination information associated with the search query.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: September 17, 2019
    Assignee: YAHOO JAPAN CORPORATION
    Inventors: Yuichi Nakamura, Shinichiro Yasui, Kazuo Yamashita, Masashi Kusano
  • Publication number: 20190214108
    Abstract: The present invention provides a novel method for classifying antibodies. Specifically, the present invention provides, for a first immunological entity and a second immunological entity, a method for classifying whether a binding epitope is the same or different, and a method for performing clustering based on the classification, the methods including: identifying an array of immunological entities such as antibodies as several portions (for example, a framework region and three CDRs); in order to define a storage region, using the array as a three-dimensional structure model; introducing an index of similarity such as structure and/or array characteristic amounts into an evaluation function for evaluating the similarity or dissimilarity of two immunological entities; and analogizing the similarity of an epitope on the basis of the similarity of an antibody.
    Type: Application
    Filed: September 15, 2017
    Publication date: July 11, 2019
    Inventors: Daron Michaelangelo Standley, John David Oakley Nieri, Songling Li, Dimitri Schritt, Kazuo Yamashita
  • Patent number: 10333303
    Abstract: A power supply device includes an output circuit configured to be supplied with electric power from a power supply, and to output a current, a driving circuit configured to control an output operation of the output circuit to output a current, an overcurrent detection circuit configured to output a detection signal to a first node when detecting an overcurrent in the output circuit, an off-state fixing circuit configured to output an off-state fixing signal to the driving circuit for performing a forcible suspension of the output operation of the output circuit based on a detection signal inputted to the first node, regardless of whether a control signal is outputted, and a control unit configured to receive the detection signal and to output the control signal for controlling the output operation to the driving circuit in order to cause the driving circuit to control the output operation.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: June 25, 2019
    Assignee: SHINDENGEN ELECTRIC MANUFACTURING CO., LTD.
    Inventors: Yoshinori Kobayashi, Kazuo Yamashita
  • Patent number: 10326290
    Abstract: A power converting device converts any of DC voltages outputted from at least two DC power supplies and outputs a converted voltage. A control unit of the power converting device determines whether a first contact and a second contact of a switch are melted and joined together based on a detection signal, before a second DC power supply outputs a second DC voltage.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: June 18, 2019
    Assignee: SHINDENGEN ELECTRIC MANUFACTURING CO., LTD.
    Inventors: Masataka Ikeda, Seiichi Ando, Kazuo Yamashita
  • Publication number: 20180241230
    Abstract: A power converting device converts any of DC voltages outputted from at least two DC power supplies and outputs a converted voltage. A control unit of the power converting device determines whether a first contact and a second contact of a switch are melted and joined together based on a detection signal, before a second DC power supply outputs a second DC voltage.
    Type: Application
    Filed: September 4, 2015
    Publication date: August 23, 2018
    Applicant: SHINDENGEN ELECTRIC MANUFACTURING CO., LTD.
    Inventors: Masataka IKEDA, Seiichi ANDO, Kazuo YAMASHITA
  • Patent number: 9637096
    Abstract: A vehicle control apparatus is equipped with a vehicle velocity detecting unit that detects a vehicle velocity of a driver's own vehicle, and an automatic brake control unit configured to carry out an automatic brake control process for causing a braking force to be generated automatically in the wheels without reliance on a braking operation when the vehicle is involved in a collision. The automatic brake control unit makes the braking force to the wheels smaller as the vehicle velocity becomes higher after the vehicle collision.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: May 2, 2017
    Assignee: Honda Motor Co., Ltd.
    Inventors: Shotaro Odate, Tsutomu Terasaki, Kazuo Yamashita, Kazuhiro Daidou, Yoshinori Noguchi, Shinji Sato
  • Publication number: 20160078105
    Abstract: A detailed information providing server includes: an acquisition unit configured to acquire search log information in which a search query is associated with link destination information of a search result obtained by a search using the search query; and a storage unit configured to determine whether or not a keyword corresponding to the search query is included in a news article available on the Internet, and store detailed information in association with the news article into an associated information DB when determining that the keyword is included, the detailed information being acquired by making access according to the link destination information associated with the search query.
    Type: Application
    Filed: September 4, 2015
    Publication date: March 17, 2016
    Inventors: Yuichi NAKAMURA, Shinichiro YASUI, Kazuo YAMASHITA, Masashi KUSANO
  • Publication number: 20150360655
    Abstract: A vehicle control apparatus is equipped with a vehicle velocity detecting unit that detects a vehicle velocity of a driver's own vehicle, and an automatic brake control unit configured to carry out an automatic brake control process for causing a braking force to be generated automatically in the wheels without reliance on a braking operation when the vehicle is involved in a collision. The automatic brake control unit makes the braking force to the wheels smaller as the vehicle velocity becomes higher after the vehicle collision.
    Type: Application
    Filed: June 11, 2015
    Publication date: December 17, 2015
    Inventors: Shotaro ODATE, Tsutomu TERASAKI, Kazuo YAMASHITA, Kazuhiro DAIDOU, Yoshinori NOGUCHI, Shinji SATO
  • Publication number: 20150228457
    Abstract: In the present invention, a gas supply method includes a selecting step and an additive gas supply step. The selecting step involves selecting, in accordance with the type of target film to be processed, a combination of a gas chamber into which additive gas is supplied and the type of additive gas, the gas chamber being selected from a plurality of gas chambers which are divided from a gas injection unit for injecting plasma processing gases into a processing chamber in which a substrate formed with a processing target film is placed. In the additive gas supply step, the additive gas is supplied to the gas chamber on the basis of the combination selected in the selecting step.
    Type: Application
    Filed: September 10, 2013
    Publication date: August 13, 2015
    Applicant: TOKYO ELECTRON LIMITED
    Inventors: Kazuo Yamashita, Yuichirou Sekimoto, Atsushi Sawachi
  • Patent number: 8017101
    Abstract: Carbon dioxide containing gas is blown into a calcium hydroxide slurry having a calcium hydroxide concentration of 100 to 400 g/L obtained by wet slaking calcined lime with 4 N hydrochloric acid activity (value at 3 minutes) of 150 to 400 mL to allow them to react until the carbonation rate becomes 50 to 85%, then 1 to 20% by volume of the calcium hydroxide slurry is added, and carbon dioxide containing gas is further blown in to terminate the reaction. The calcium carbonate obtained by this method is precipitated calcium carbonate aggregates having a secondary particle diameter of 1 to 10 ?m and consisting of primary particles having a long diameter of 0.5 to 3.0 ?m, a short diameter of 0.1 to 1.0 ?m and an aspect ratio of 3 or more, has superior characteristics due to a BET specific surface area in the range of 8 to 20 m2/g and a pore volume in the range of 1.5 to 3.5 cm3/g, can be uniformly dispersed in pulp fiber, and thereby can be used to manufacture high bulk paper.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: September 13, 2011
    Assignee: Okutama Kogyo Co., Ltd.
    Inventors: Kazuo Yamashita, Kazuhisa Shimono, Toru Kawazu, Tatsuo Takano
  • Patent number: 8012443
    Abstract: When spherical calcium carbonate is produced by blowing a carbon dioxide gas or a carbon dioxide-containing gas into an aqueous suspension containing calcium hydroxide to react them, after start of the reaction, an aqueous solution or suspension of a water-soluble phosphoric acid compound or a water-soluble salt thereof is added to the reaction mixture when carbonation ratio reaches 2 to 10%, and the reaction is further allowed to continue at a low gas blowing rate of 1.0 NL/minute or lower (step (a)). Subsequently, an aqueous suspension containing calcium hydroxide and an aqueous solution or suspension of a water-soluble phosphoric acid compound or a water-soluble salt thereof are added to the reaction mixture, and a carbon dioxide gas or a carbon dioxide-containing gas is introduced to allow to react and thereby produce spherical calcium carbonate having a mean particle diameter of 10 ?m or larger.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: September 6, 2011
    Assignee: Okutama Kogyo Co., Ltd.
    Inventors: Kenshiro Makino, Kazuo Yamashita
  • Publication number: 20100239511
    Abstract: When spherical calcium carbonate is produced by blowing a carbon dioxide gas or a carbon dioxide-containing gas into an aqueous suspension containing calcium hydroxide to react them, after start of the reaction, an aqueous solution or suspension of a water-soluble phosphoric acid compound or a water-soluble salt thereof is added to the reaction mixture when carbonation ratio reaches 2 to 10%, and the reaction is further allowed to continue at a low gas blowing rate of 1.0 NL/minute or lower (step (a)). Subsequently, an aqueous suspension containing calcium hydroxide and an aqueous solution or suspension of a water-soluble phosphoric acid compound or a water-soluble salt thereof are added to the reaction mixture, and a carbon dioxide gas or a carbon dioxide-containing gas is introduced to allow to react and thereby produce spherical calcium carbonate having a mean particle diameter of 10 ?m or larger.
    Type: Application
    Filed: June 1, 2010
    Publication date: September 23, 2010
    Applicant: OKUTAMA KOGYO CO., LTD.
    Inventors: Kenshiro MAKINO, Kazuo YAMASHITA