Patents by Inventor Kazuya Okamoto

Kazuya Okamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10120043
    Abstract: In one embodiment, a magnetic resonance apparatus includes a gradient coil configured to be cylindrically-shaped and to apply a gradient magnetic field to a hollow region into which an object is inserted, the hollow region being formed, the hollow region being formed inside the gradient coil; and an RF coil configured to include a resonance circuit whose plural connecting conductors are folded back at one end side of the gradient coil so that the resonance circuit extends from the hollow region to an outer region of the gradient coil.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: November 6, 2018
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventor: Kazuya Okamoto
  • Publication number: 20180289840
    Abstract: To provide method for evaluating hematotoxicity of drug to be evaluated, which is excellent in clinical predictability regarding toxicity to the bone marrow, and model for evaluating hematotoxicity of drug to be evaluated. The method for evaluating the hematotoxicity of the drug to be evaluated, the method including: administering the drug to be evaluated to humanized, transgenic NOG mouse, which is obtained by introducing human GM-CSF/IL-3 gene into NOG mouse and the number of human-derived leucocytes in leucocytes in blood thereof is 20% or more; and evaluating that the drug to be evaluated has the hematotoxicity when sample of the humanized, transgenic NOG mouse after the administering the drug to be evaluated is measured for number of cells of human-derived hemocytes, the number of the cells of the human-derived hemocytes is changed compared to control to which vehicle is administered instead of the drug to be evaluated.
    Type: Application
    Filed: May 24, 2016
    Publication date: October 11, 2018
    Inventors: Kazuya Okamoto, Daichi Nagai, Mamoru Ito, Ryoji Ito
  • Patent number: 10080534
    Abstract: A medical image diagnostic device according to an embodiment includes a first collector, a second collector, and an image generator. The first collector collects data from a first region of a subject through a first detector. The second collector collects data from a second region of the subject that is different from the first region through a second detector. The image generator generates a first diagnostic image from the data collected by the first collector and generates a second diagnostic image from the data collected by the second collector.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: September 25, 2018
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Hitoshi Yamagata, Kazuya Okamoto, Takuzo Takayama
  • Patent number: 10067207
    Abstract: A positron emission tomography (PET)-magnetic resonance imaging (MRI) apparatus according to an embodiment includes a gantry having a static magnetic field magnet, a gradient coil, and a radio frequency coil, a PET detector, and a moving mechanism. The static magnetic field magnet generates a static magnetic field in a bore having an approximately cylindrical shape. The gradient coil is disposed on an inner circumference side of the static magnetic field magnet and applies a gradient magnetic field to an object disposed in the bore. The radio frequency coil is disposed on an inner circumference side of the gradient coil and applies a radio frequency magnetic field to the object. The PET detector detects gamma rays emitted from a positron-emitting radionuclide injected into the object. The moving mechanism causes the PET detector in the gantry along the axial direction of the bore.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: September 4, 2018
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Kazuya Okamoto, Takuzo Takayama, Hitoshi Yamagata
  • Patent number: 10067206
    Abstract: A medical image diagnosis apparatus according to an embodiment includes: a first image taking unit, a second image taking unit, a position specifying unit, and a moving controlling unit. The first image taking unit performs an image taking process by implementing PET while using a first PET detector and a second PET detector. The position specifying unit specifies positions of the first PET detector and the second PET detector, on the basis of a medical image taken by the second image taking unit. The moving controlling unit controls moving of the first PET detector and the second PET detector in accordance with the specified positions. The first image taking unit and the second image taking unit each perform the image taking process after the first PET detector and the second PET detector have been moved.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: September 4, 2018
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Takuzo Takayama, Hitoshi Yamagata, Kazuya Okamoto
  • Publication number: 20180245501
    Abstract: A changeover valve includes: a valve body portion that closes an opening formed at a switching position of an exhaust flow path; a fixing portion that rotatably fixes the valve body portion; a first raised portion protruding at one of a flow path forming portion and the fixing portion; a cushion portion; a second raised portion protruding at the valve body portion; and a biasing portion that biases the valve body portion. The first raised portion has an inclined portion inclined relative to a valve closing direction and the second raised portion has an inclined portion inclined relative to the valve closing direction. Both of the inclined portions are contactable with each other at the time of valve closing.
    Type: Application
    Filed: November 10, 2015
    Publication date: August 30, 2018
    Inventors: Munehiro Tsubosaka, Yusuke Hiramatsu, Yasushi Okamoto, Kazuya Okamoto, Yasufumi Umeno
  • Patent number: 10026768
    Abstract: A detector comprises a plurality of photoelectric converters to output an electrical signal corresponding to an incident light, and a plurality of filter circuits provided corresponding to each of the plurality of photoelectric converters or to each of a plurality of element groups respectively including a predetermined number of the photoelectric converters of the plurality of photoelectric converters, the plurality of filter circuits attenuating a signal having a predetermined frequency from the electrical signal output from the plurality of photoelectric converters, In the above-described detector, the plurality of photoelectric converters may be provided in a first substrate, and the plurality of filter circuits may be provided in a second substrate laminated on the first substrate.
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: July 17, 2018
    Assignee: NIKON CORPORATION
    Inventors: Osamu Saruwatari, Shigeru Aoki, Kazuya Okamoto, Isao Sugaya, Masashi Okada, Hiroshi Ohki
  • Patent number: 10001534
    Abstract: According to one embodiment, an MRI apparatus includes a first radio communication unit, a second radio communication unit and an image reconstruction unit. The first radio communication unit includes a connecting unit detachably connected to an RF coil device which detects a nuclear magnetic resonance signal emitted from an object. The first radio communication unit acquires the nuclear magnetic resonance signal detected by the RF coil device via the connecting unit, and wirelessly transmits the acquired nuclear magnetic resonance signal. The second radio communication unit receives the nuclear magnetic resonance signal wirelessly transmitted from the first radio communication unit. The image reconstruction unit acquires the nuclear magnetic resonance signal received by the second radio communication unit, and reconstructs image data of the object based on the nuclear magnetic resonance signal.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: June 19, 2018
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventor: Kazuya Okamoto
  • Patent number: 10000508
    Abstract: A crystalline dimethyl 2-(benzyloxy)-1-(2,2-diethoxy-ethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate of the formula (U1):
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: June 19, 2018
    Assignee: Shionogi & Co., Ltd
    Inventors: Yukihito Sumino, Moriyasu Masui, Daisuke Yamada, Fumiya Ikarashi, Kazuya Okamoto
  • Patent number: 9983278
    Abstract: According to one embodiment, an MRI apparatus includes a data acquisition system and a control system. The data acquisition system acquires MR signals from a subject. The control system acquires the MR signals by controlling the data acquisition system to generate image data. The data acquisition system has a WB coil, an RF coil and a breaker circuit. The WB coil applies the RF magnetic field to the imaging area. The RF coil applies the RF magnetic field to the imaging area when an RF pulse has been applied from the control system through a connector. The RF coil is set inside the WB coil. The breaker circuit electrically breaks a part of a circuit constituting the RF coil when the connector of the RF coil has been disconnected to the control system.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: May 29, 2018
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventors: Kazuya Okamoto, Manabu Ishii
  • Patent number: 9969750
    Abstract: A process for preparing a compound shown by formula (W6): wherein each Hal is independently chloro or bromo, using a novel process for preparing a pyridine derivative represented by formula (W2), wherein R6d is as defined herein.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: May 15, 2018
    Assignee: Shionogi and Co., Ltd.
    Inventors: Yukihito Sumino, Moriyasu Masui, Daisuke Yamada, Fumiya Ikarashi, Kazuya Okamoto
  • Patent number: 9951051
    Abstract: The present invention relates to a Sonogashira-Carbonylation reaction using two types of gas, as well as novel crystals which can control a heat of the said reaction and the process of producing the same. In addition, the present invention relates to a ligand (additive) to prevent the deactivation of a palladium catalyst.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: April 24, 2018
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Genta Tadano, Fumiya Ikarashi, Kazuya Okamoto, Toshikatsu Maki, Motoyuki Hagihara
  • Publication number: 20180106878
    Abstract: According to one embodiment, a magnetic resonance imaging apparatus provided with a plurality of transmission channels includes a signal processing unit and a control unit. The signal processing unit acquires a radio frequency magnetic field emitted from each of the plurality of transmission channels through a receiver coil mounted on an object and measure a phase of the radio frequency magnetic field. The control unit determines a phase difference between the plurality of transmission channels based on the phase of the radio frequency magnetic field of each of the plurality of transmission channels measured by the signal processing unit. The control unit controls a phase of a radio frequency pulse inputted to each of the plurality of transmission channels, based on the phase difference.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 19, 2018
    Inventors: Kazuyuki SOEJIMA, Haruki NAKAMURA, Takuma KAWAI, Kazuya OKAMOTO
  • Patent number: 9919508
    Abstract: A substrate aligning apparatus comprising: an aligning section that aligns a first substrate and a second substrate together; an acquiring section that acquires positional information on at least one of the first substrate and the second substrate, by the time the first substrate and the second substrate which have been aligned in the aligning section are carried out from the aligning section; a judging that judges misalignment of the first substrate and the second substrate, based on information acquired by the acquiring section.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: March 20, 2018
    Assignee: NIKON CORPORATION
    Inventors: Kazuya Okamoto, Isao Sugaya
  • Publication number: 20180044351
    Abstract: A process for preparing a compound represented by formula (Y1) or (Y2) [wherein IV is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d is hydrogen, a lower alkyl optionally substituted with substituent E, or the like; R4d is a lower alkyl optionally substituted with substituent E, or the like; and R6d is a lower alkyl group optionally substituted with substituent group E, or the like].
    Type: Application
    Filed: September 20, 2017
    Publication date: February 15, 2018
    Inventors: Yukihito SUMINO, Moriyasu MASUI, Daisuke YAMADA, Fumiya IKARASHI, Kazuya OKAMOTO
  • Publication number: 20180037593
    Abstract: A process for preparing a compound represented by formula (Y1) or (Y2) [wherein Rx is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d is hydrogen, a lower alkyl optionally substituted with substituent E, or the like; R4d is a lower alkyl optionally substituted with substituent E, or the like; and R6d is a lower alkyl group optionally substituted with substituent group E, or the like].
    Type: Application
    Filed: September 20, 2017
    Publication date: February 8, 2018
    Inventors: Yukihito SUMINO, Moriyasu MASUI, Daisuke YAMADA, Fumiya IKARASHI, Kazuya OKAMOTO
  • Publication number: 20180037591
    Abstract: A process for preparing a compound represented by formula (Y1) or (Y2) [wherein RX is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d is hydrogen, a lower alkyl optionally substituted with substituent E, or the like; R4d is a lower alkyl optionally substituted with substituent E, or the like; and R6d is a lower alkyl group optionally substituted with substituent group E, or the like].
    Type: Application
    Filed: September 20, 2017
    Publication date: February 8, 2018
    Inventors: Yukihito SUMINO, Moriyasu MASUI, Daisuke YAMADA, Fumiya IKARASHI, Kazuya OKAMOTO
  • Publication number: 20180037592
    Abstract: A process for preparing a compound represented by formula (Y1) or (Y2) [wherein Rx is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d is hydrogen, a lower alkyl optionally substituted with substituent E, or the like; R4d is a lower alkyl optionally substituted with substituent E, or the like; and R6d is a lower alkyl group optionally substituted with substituent group E, or the like].
    Type: Application
    Filed: September 20, 2017
    Publication date: February 8, 2018
    Inventors: Yukihito SUMINO, Moriyasu MASUI, Daisuke YAMADA, Fumiya IKARASHI, Kazuya OKAMOTO
  • Publication number: 20180028092
    Abstract: A PET-MRI apparatus according to an embodiment includes a static magnetic field magnet, a gradient coil, a birdcage-type radio frequency coil, and at least one PET detector. The static magnetic field magnet is configured to generate a static magnetic field. The gradient coil is configured to apply a gradient magnetic field to a subject placed in the static magnetic field. The radio frequency coil includes two end rings and a plurality of rungs arranged at intervals along a circumferential direction of the end rings and is configured to transmit a radio frequency pulse or to receive a magnetic resonance signal from the subject. Further, the PET detector is housed inside a conductor structuring the rungs of the radio frequency coil.
    Type: Application
    Filed: July 17, 2017
    Publication date: February 1, 2018
    Applicant: Toshiba Medical Systems Corporation
    Inventors: Kazuya OKAMOTO, Kazuto NAKABAYASHI
  • Patent number: D809627
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: February 6, 2018
    Assignee: Koganei Corporation
    Inventors: Akira Watanabe, Koichi Teraki, Joji Inaba, Hirokazu Ohki, Kazuya Okamoto