Abstract: Provided herein are substantially non-luminescent peptide/polypeptide tags that are inserted internally within a protein of interest or between N-terminal and C-terminal peptides/polypeptides. Interaction of the internally-inserted tag with a complement polypeptide/peptide that is also substantially non-luminescent results in the formation a bioluminescent reporter complex.

Abstract: Disclosed herein are compounds, compositions, and methods for treating infections by bacteria and for killing bacteria. In particular, the disclosed compounds, compositions, and methods are useful for treating infections by bacteria and for killing persister bacteria that survive antibiotic treatment and then reconstitute infections.

Abstract: Provided herein are substantially non-luminescent peptide/polypeptide tags that are inserted internally within a protein of interest or between N-terminal and C-terminal peptides/polypeptides. Interaction of the internally-inserted tag with a complement polypeptide/peptide that is also substantially non-luminescent results in the formation a bioluminescent reporter complex.

Abstract: Systems, methods, and apparatuses may include a network onboarding manager for configuring network security features at application hosting sites of a service provider network, for instance, as part of a procedure for deploying an application onto the service provider network. The network onboarding manager may generate a security profile for the application. The security profile may include information indicating a security posture of the application with respect to network security features needed to deploy the application, which the system may use to generate and send configuration data to the hosting sites. One or more operations may be performed based on a user input received at a developer portal (e.g., via a user interface), or automatically based on one or more API calls made by the network onboarding manager and/or based on one or more security profile templates.

Abstract: An electronic gaming machine includes a game display having a graphical user interface (GUI). A game controller is in communication with the game display. The game controller controls the GUI to present a selectable tournament button that causes the player to enter a game tournament, displays a plurality of selectable tournament game options for the game tournament, receives a tournament game selection response indicating a selected one of the options, displays the selected tournament game, displays at the GUI during the selected tournament game, an exit button that returns the display to the base game and maintains player progress in the selected tournament game, re-displays the tournament button upon returning to the base game, the re-displayed tournament button enables the player to return to the selected tournament game with the maintained player progress, and displays a prompt to card-in, and provide an enhanced return to player (RTP).

Abstract: Provided herein are bioluminescent polypeptides and compositions and methods for the assembly of a tripartite or multipartite bioluminescent complex. In particular embodiments, a bioluminescent complex is formed upon the interaction of three or more peptide and/or polypeptide components.

Abstract: An electronic gaming machine includes a game display with a graphical user interface (GUI) configured to receive an input from a player and a game controller. The game controller is configured to execute instructions stored in a memory. The instructions cause the game controller to control the GUI to present a selectable tournament button that causes the game controller to enter the player into a tournament. Upon receiving a tournament button selection a plurality of selectable tournament game options for the game tournament are displayed. The GUI receives a tournament game response indicating a the tournament game selected and the tournament game is displayed. A return button is displayed that returns the display to the base game and maintains player progress in the tournament. The tournament button is re-displayed enabling the player to return to the selected tournament game with the maintained player progress.

Abstract: The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture fusions), surfaces (e.g., displaying, capture ligands, capture proteins, or capture fusions), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.

Abstract: Disclosed is an improved approach for implementing a system, method, and computer program product for integrating with a social media site, which can be used to create and configure a custom audience on the social media site.

Abstract: Provided herein are systems and methods for characterizing target/ligand engagement. In particular, luciferase-labeled polypeptide targets are used to detect or quantify target/ligand engagement (e.g., within a cell or cell lysate).

Abstract: Provided herein are systems and methods for characterizing target/ligand engagement. In particular, luciferase-labeled polypeptide targets are used to detect or quantify target/ligand engagement (e.g., within a cell or cell lysate).

Abstract: Techniques for proxy based network access are discussed herein. In some examples, the techniques can be implemented in a network proxy device for Citizens Broadband Radio Service (CBRS). A base station or a domain proxy device may manage or otherwise use CBRS resources by exchanging signaling messages with a Spectrum Access System (SAS). The base station or domain proxy device may transmit signaling messages in a first private network to a network device bridging the first private network and a second private network with limited access to a public network. The network device send proxy message(s) in response to the signaling messages to the SAS and can establish an encrypted session layer or application layer tunnel between the base station and/or domain proxy device. The proxy based network access preserves secure networks while still allowing limited messaging with other public or private networks.

Abstract: An electronic gaming machine includes a game display with a graphical user interface (GUI) configured to receive an input from a player and a game controller. The game controller is configured to execute instructions stored in a memory. The instructions cause the game controller to control the GUI to present a selectable tournament button that causes the game controller to enter the player into a tournament. Upon receiving a tournament button selection a plurality of selectable tournament game options for the game tournament are displayed. The GUI receives a tournament game response indicating a the tournament game selected and the tournament game is displayed. A return button is displayed that returns the display to the base game and maintains player progress in the tournament. The tournament button is re-dispayed enabling the player to return to the selected tournament game with the maintained player progress.

Abstract: Provided herein are palladium (Pd) catalysts with improved performance in biological environments. In particular, formulations, methods of preparations, and storage conditions are provided that provide improved performance of Pd catalysts under protein-rich conditions.

Abstract: Provided herein are compounds, compositions, and methods for delivering biomolecules to cells. In particular, the present disclosure provides modified polyamine polymers, including polyamine polymers having fluorinated substituents.

Abstract: Provided herein are systems and methods for the detection of an analyte or analytes in a sample. In particular, the present disclosure provides compositions, assays, and methods for detecting and/or quantifying a target analyte using a bioluminescent complex comprising substrates, peptides, and/or polypeptides capable of generating a bioluminescent signal that correlates to the presence, absence, or amount of the target analyte.

Abstract: Techniques for proxy based network access are discussed herein. In some examples, the techniques can be implemented in a network proxy device for Citizens Broadband Radio Service (CBRS). A base station or a domain proxy device may manage or otherwise use CBRS resources by exchanging signaling messages with a Spectrum Access System (SAS). The base station or domain proxy device may transmit signaling messages in a first private network to a network device bridging the first private network and a second private network with limited access to a public network. The network device send proxy message(s) in response to the signaling messages to the SAS and can establish an encrypted session layer or application layer tunnel between the base station and/or domain proxy device. The proxy based network access preserves secure networks while still allowing limited messaging with other public or private networks.

Abstract: Provided herein are compositions and methods for photoaffinity labeling of molecular targets. In particular, probes that specifically interact with cellular targets based on their affinity and are then covalently linked to the cellular target via a photoreactive group (PRG) on the probe.

Abstract: An electronic gaming machine, including a player interface, a game display, and a game controller. The player interface is configured to receive player selections from a player. The game controller is coupled to the player interface and the game display. The game controller is configured to control the game display to present the player an option to participate in a wagering game tournament, to receive, from the player interface according to the player selections, a first selection to participate in the wagering game tournament, to control the game display to present the player an option to select from among a plurality of games for the wagering game tournament, to receive, from the player interface according to the player selections, a second selection of a tournament game from the plurality of games, and conduct the tournament game via the player interface and the game display.

Abstract: Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.