Abstract: The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.

Abstract: A gaming system is provided. The gaming system may include a game display configured to display a game interface including a matrix having a plurality of rows including a plurality of matrix positions and a processor configured to determine a number of wild symbols currently displayed in the matrix, in response to determining the number of wild symbols currently displayed in the matrix exceeds a threshold number, determine a number of spin credits, in response to the number of spin credits being greater than zero, determine a weighting factor defining a probability for displaying a symbol in a respective matrix position, apply the determined weighting factors to respective lookup tables for each matrix position not currently displaying a wild symbol, and determine, for each matrix position not currently displaying a wild symbol, a symbol to display.

Abstract: An electronic gaming device that includes a display device, an input device, a memory device, and a processor is described. The processor causes to be displayed a dual symbol configured as a wild symbol and as a credit on reel (or cash-on-reel) symbol that indicates a prize to be awarded if a trigger symbol also lands in the same row as the dual symbol. The processor causes a base game to be initiated that includes causing symbols to be displayed on reels within a display matrix on a display device wherein each reel is configured to spin. During game play of the base game, the dual symbol, if displayed, persists between different reel spins and moves up one row each reel spin from a previous symbol position to a new symbol position.

Abstract: The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.

Abstract: A dispensing system (40) includes a body (54) having an outer wall (64) defining a volume for storing a substance, the outer wall (64) having a top end (66) and a sealed bottom end (70). The top end (66) is covered by a flexible lid (56) that is attached to the body (54). The lid (56) has a press portion (88) for being engaged to move the lid (56) from a first position into a second, deflected position. A post (58) is connected to the lid (56) and is configured in the second position of the lid (56) to breach the sealed bottom end (70) forming a dispensing orifice (80) to accommodate movement of a substance out of the body (54). In one form, the outer wall (64) includes at least one bottle stop projection (218) defining one or more vent channels (219).

Abstract: Multi-function stairlift connectivity includes a stairlift data collection system having data collection devices communicatively connected to a main controller. Such data collection devices may include sensors, switches, controllers, detectors, control boards, and location detectors providing data and settings in a stairlift (e.g., diagnostic information, system status data, faults, drive performance data). A communication module receives collected stairlift data and communicates wirelessly with a remote communication device. Waypoint detection may include stairlift carriage position detection employing electrical contacts on a stairlift carriage. Carriage position can be determined when the carriage stops at or passes a waypoint marker that includes electrical contacts connected to a waypoint element possessing a detectable electromagnetic characteristic (e.g., an identifiable resistive value).

Abstract: The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.

Abstract: A gastrointestinal implant device comprises a proximal element configured to reside in a stomach to resist distal migration; a distal element configured to reside in an intestine to resist proximal migration, and one or more tethers coupling the proximal element to the distal element. The distal element comprises a wave anchor and a surface roughness element on a surface of at least a portion of the wave anchor. Delivery systems and retrieval techniques are also provided.

Abstract: It is possible to control access to content by means such as a method which comprises steps including receiving, at a content management platform, a set of data from a content creator. The set of data could comprise content and one or more restrictions on accessing the content. A key could then be generated for that content, as could a record associating the content with the one or more restrictions. Data comprising that key could then be sent over a network, and a content access request message comprising the key could be received from a remotely located host platform. The content access request message could be compared with the one or more restrictions, and, based on that comparison, the content access request message could be responded to with a page providing the content or an error page.

Abstract: A tamper-evident closure (40) is provided for a container. In one particular embodiment, the closure (40) has a body (42) and a hinged lid (44), and has the following additional features as next described. A tamper-indicating tab (120) is connected to the lid (44) by a frangible junction (130). A pressing member (150) is connected to the closure body (42) for movement from an initial unactuated configuration and to an inwardly deformed, actuated configuration. A post (170) is provided on either the pressing member (150) or tab (120), and a slot (140) is defined in the other of the pressing member (150) and tab (120), wherein the slot (140) non-releasably receives the post (170) when the lid (44) is first closed. The closure body (42) also has an inwardly located retention wall (160) defining an aperture (164).

Abstract: A tamper-evident closure (40) is provided for a container. In one particular embodiment, the closure (40) has a body (42) and a hinged lid (44), and has the following additional features as next described. A tamper-indicating tab (120) is connected to the lid (44) by a frangible junction (130). A pressing member (150) is connected to the closure body (42) for movement from an initial unactuated configuration and to an inwardly deformed, actuated configuration. A post (170) is provided on either the pressing member (150) or tab (120), and a slot (140) is defined in the other of the pressing member (150) and tab (120), wherein the slot (140) non-releasably receives the post (170) when the lid (44) is first closed. The closure body (42) also has an inwardly located retention wall (160) defining an aperture (164).

Abstract: A projectile illuminated by a chemiluminescent light source is capable of producing a stroboscopic effect when set in motion. The projectile body is a solid body preferably made of a soft, pliable material such as NERF®, in the shape of a sports ball, and the light propagates, unobstructed, through orifices in the body that allow for maximum light transmission. There need not be any ancillary components, only the light stick(s) and the soft, pliable body, however, an optional housing may be included to contain the light source. Orifices through which the light escapes the body may be modeled in the shape of team or corporate logos.

Abstract: A carrier ring assembly is provided for use with a closure for a container. The carrier ring assembly includes a carrier ring and a valve. The carrier ring includes a retention bead and a retention space. The valve is located at least partially within the carrier ring and has a retention portion positioned within the retention space.

Abstract: A battery powered high-intensity illumination device enclosed in a waterproof housing is adapted for removable attachment to a surface adjacent to a lock. Upon removing the device from the surface, one may easily transport it in the palm of one's hand or in a pocket, because of its compact, ergonomic size and shape. Activation of the device may be automatic, triggered by motion detection or a touch-sensitive switch. An internal shutoff timing circuit ensures hands free operation and energy efficiency. Angular adjustment allows the housing to be rotated so as to fixably alter the angle of the light beam with respect to the illumination target. A reflector allows the light source to be shielded from view and for light output to be focused on an area of interest. The size, shape, and appearance of the lock light are appealing and unique features of the device.

Abstract: A dispensing closure system for use with an associated container includes a closure assembly having a closure base, and a lid moveably connected to the closure base. The present preferred embodiment of the closure includes a slider element mounted on an upper surface of the closure base for lateral movement between unactuated and actuated positions. The provision of camming surfaces on the slider element, which cooperate with the closure lid, permit convenient, push-button opening of the closure lid to facilitate convenient use by consumers.

Abstract: A projectile illuminated by a chemiluminescent light source is capable of producing a stroboscopic effect when set in motion. The projectile body is a solid body preferably made of a soft, pliable material such as NERF®, in the shape of a sports ball, and the light propagates, unobstructed, through orifices in the body that allow for maximum light transmission. There need not be any ancillary components, only the light stick(s) and the soft, pliable body, however, an optional housing may be included to contain the light source. Orifices through which the light escapes the body may be modeled in the shape of team or corporate logos.

Abstract: A battery powered, waterproof high intensity LED enclosed in a waterproof housing that is adapted for adhesive or magnetic attachment to a surface in the proximity of a lock. A motion detector means activates the device to switch on the LED/s. A internal timing circuit ensures the hands free operation of the light as well as to ensure that the LED shuts off after a predetermined time. An angle adjusting means allows the housing to be adjusted so as to fixably alter the angle between the light beam and the housing base. A reflector means allows the beam to be concentrated and focused on the area of interest.

Abstract: A subwoofer stereo system with a docking base for docking a portable digital media player comprises a generally hexahedron cabinet made of a panel material for encasing at least an electronic media processing unit and an amplifier for driving stereo speakers. The docking base has an attachment of modular connector board having at least one main connector for the portable digital player and at least one auxiliary phone plug. The docking base is mounted through the top panel extending in part inwardly of the cabinet as well as outwardly in part for receiving the portable player. A first shielding chamber extends from under the top panel invisibly to enclose the inward part of the docking base to isolate it from interior of the cabinet and a second shielding chamber extends from behind under the front panel invisibly to enclose the control interface to isolate it from interior of the cabinet.