Abstract: The present invention provides anti-LRP5/6 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for treating diseases and disorders associated with Wnt pathway signaling.

Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

Abstract: A data comparison device holds first and second encrypted data of first and second plaintext, respectively. The first plaintext is divided into a plurality of blocks and the first encrypted data is generated by executing encryption of each of the plurality of blocks and shuffling of the plurality of blocks. The second plaintext is divided into a plurality of blocks and the second encrypted data is generated by executing encryption of each of the plurality of blocks. In at least one of the first encrypted data and the second encrypted data, a plaintext value is embedded as a value indicating a magnitude comparison result, and the data comparison device compares blocks at the same position before shuffling of the first encrypted data and the second encrypted data based on the embedded value and determines a magnitude relationship between the first plaintext and the second plaintext.

Abstract: The present disclosure provides tissue-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in targeted tissues.

Abstract: A material comprising: a support 10; and a brush layer 20 containing a brush-like polymer chain assemblage 21 formed of a plurality of polymer chains and a swelling liquid 22, in which a brush layer 20 is swollen with the swelling liquid 22, the brush layer 20 retaining on the surface a lubricating liquid 30, and the swelling liquid 22 contained in the brush layer 20 and the lubricating liquid 30 being phase-separated to form a liquid-liquid phase separation interface 40 in between and a sliding system using the material.

Abstract: A mobile terminal includes a light source, a camera, a display, and a processor configured to, when a comparison region of a target is imaged, display on the display a guide image at an angle of rotation responsive to information related to a positional relationship of the camera and the light source, the guide image being used to image the comparison region, with a relative position and posture of the light source, the camera, and the comparison region satisfying a specific relationship.

Abstract: A fastened member such as a hinge which is a metal fastened member to be fastened with at least one fastener to at least one attachment surface of at least one target object such as a construction machine to which the fastened member is to be attached, the at least one target object containing steel, the fastened member including at least one contact surface to make contact with the at least one attachment surface, the at least one contact surface at least partially including at least one exposure portion where material having a higher ionization tendency than steel is exposed, wherein a portion of the fastened member that is other than the at least one contact surface is coated with a coating.

Abstract: Provided is a compound represented by formula (1): In the formula, A represents a polymerizable group; L represents an optionally branched (n+1)-valent linking group; R1 represents an aromatic ring group optionally having a substituent; R2 represents a monovalent organic group optionally having a substituent; X1 and X2 each independently represent an oxygen atom, a sulfur atom, or a nitrogen atom optionally having a substituent; m represents an integer of 0 or 1; n represents an integer of 1 to 3; and p represents an integer of 0 or 1. The two R1s may be bonded together at any position to form a ring structure and R1=R2, X1=X2, and p=1 do not hold simultaneously. The compound simultaneously has a high refractive index and high transparency.

Abstract: An information processing apparatus includes a processor configured to simultaneously perform a first function of assisting a user to perform a first operation on an image capturing device such that a positional relationship between an object and the image capturing device that captures an image of the object is maintained in a specific positional relationship and a second function of assisting the user to perform a second operation on the image capturing device such that an angle between the object and the image capturing device is maintained at a specific angle.

Abstract: An information processing apparatus includes a processor configured to: perform a first function of assisting a user to perform a first operation of multiple operations on an image capturing device such that posture of the image capturing device that captures an image of an object with respect to the object is maintained in specific posture; and perform a second function of assisting in performing a second operation of the multiple operations subsequent to the first operation in a case where the first operation ends.

Abstract: A collation device includes a light source unit; a camera unit that receives light emitted from the light source unit and reflected in a collation area of an object to acquire a photographed image of the collation area; a display unit; and a processor configured to, by executing a program: display a guide of a bright spot portion of the light source unit on the photographed image on the display unit so that an angle formed by the light source unit, the camera unit, and the collation area of the object is a predetermined angle.

Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

Abstract: The present invention relates to VEGF-binding agents, DLL4-binding agents, VEGF/DLL4 bispecific binding agents, and methods of using the agents for treating diseases such as cancer. The present invention provides antibodies that specifically bind human VEGF, antibodies that specifically bind human DLL4, and bispecific antibodies that specifically bind human VEGF and/or human DLL4. The present invention further provides methods of using the agents to inhibit tumor growth. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an agent or antibody of the present invention to a patient having a tumor or cancer.

Abstract: The present invention provides anti-LRP5/6 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for treating diseases and disorders associated with Wnt pathway signaling.

Abstract: A diverting agent of the present invention contains a polyvinyl alcohol-based resin, wherein when the diverting agent is added to a 0.48 mass % aqueous solution of guar gum to prepare a mixed solution having a concentration of 12 mass %, a dispersion liquid obtained by dispersing the mixed solution at 30° C.

Abstract: A collation device includes a processor configured to, by executing a program: (a) acquire a photographed image including a collation area provided on an object and a reference position area that serves as a reference for a position of the collation area; (b) detect the reference position area from the photographed image; (c) set a peripheral image area in the photographed image based on the reference position area and predetermined relative coordinates; and (d) detect the collation area in the peripheral image area.

Abstract: A timepiece includes a first motor having a rotor for rotating a hour hand, and a first train wheel group having a wheel gear rotating based on rotation of the rotor. The first train wheel group includes a third intermediate hour pinion, a first intermediate hour pinion, a twenty four hour wheel gear having a first reference load unit disposed to mesh with the third intermediate hour pinion so that a load received by the rotor fluctuates in a case where the twenty four hour wheel gear meshes with the third intermediate hour pinion, and rotating at a first reduction ratio with respect to the rotor, and a second intermediate hour wheel gear having a second reference load unit disposed to mesh with the first intermediate hour pinion so that the load received by the rotor fluctuates in a case where the second intermediate hour wheel gear meshes with the first intermediate hour pinion, and rotating at a second reduction ratio lower than the first reduction ratio with respect to the rotor.

Abstract: A collation device includes a processor configured to, by executing a program: (a) acquire a photographed image including a collation area provided on a printing substrate having unevenness, (b) simultaneously execute smoothing processing and shading difference enhancement processing on the photographed image, and (c) detect the collation area based on an image obtained by simultaneously executing the smoothing processing and the shading difference enhancement processing.

Abstract: A collation device includes a light source unit; a camera unit that receives light emitted from the light source unit and reflected in a collation area of an object to acquire a photographed image of the collation area; a display unit; and a processor configured to, by executing a program: display a guide of a bright spot portion of the light source unit on the photographed image on the display unit so that an angle formed by the light source unit, the camera unit, and the collation area of the object is a predetermined angle.

Abstract: Disclosed is a battery pack including a secondary battery and a circuit board, in which the secondary battery includes a metal exterior portion, a first external terminal, and a second external terminal, the circuit board has a plurality of connection portions connected to the first external terminal or the second external terminal, at least one of the connection portions has a first opening, and the connection portion having the first opening is solder-bonded to the first external terminal or the second external terminal.