Abstract: Provided herein are prognostic and diagnostic methods for predicting likelihood of clinical response of a subject having cancer to treatment with an immunotherapeutic agent. Also provided herein are methods for treating a subject having cancer with an immunotherapeutic agent after determining likelihood of clinical response of the subject to such treatment.

Abstract: An elastic headgear that automatically adjusts to fit patients of different sizes and shape and that may be customized through selective placement of various accessories. The headgear includes a strap member having a central panel and a first arm member and a second arm extending from the central panel. The arm members each have at least one first attachment feature. The headgear also includes at least one accessory member having at least one second attachment feature, wherein the at least one second attachment feature is selectively mateable with the at least one first attachment feature to allow the at least one accessory member to be selectively attached to and positioned along either the first arm member or the second arm member at a plurality of different locations.

Abstract: A method for controlling an actuatable restraining device includes sensing a plurality of crash event indications, classifying crash events in response to the sensed crash event indications to identify at least one of a forward rigid barrier crash event, an offset deformable barrier crash event, an angular crash event, and a small overlap crash event, and controlling deployment timing of the actuatable restraining device in response to the classification of the crash event.

Abstract: Methods and apparatuses for resonance tuning of microcavities are provided. An apparatus comprises a whispering gallery mode optical microcavity characterized by at least one resonance frequency; optical components configured to evanescently couple a probe laser beam into the microcavity; an absorber element in thermal contact with the microcavity; and optical components configured to illuminate the absorber element with a free space pump light beam, wherein the absorber element is configured to absorb energy from the free space pump light beam, thereby generating heat, and to transfer the heat to the microcavity, thereby inducing a shift in the at least one resonance frequency. The absorber element may be configured as a pillar forming an interfacial region with the microcavity at one of the ends of the pillar. The surface of the microcavity may be substantially free of a coating material.

Abstract: The present technology uses one or more separating segments, i.e. chromatography columns, aligned in series along a flow path. The separating segments are divided by a plurality of heating elements or are heated directly. The heating elements heat the supercritical mobile phase and sample to replace heat lost due to axial expansion of the mobile phase along the mobile phase flow path.

Abstract: An attachable trimmer includes a trimming unit, an arm assembly, a limit switch, and a rod assembly as the attachable trimmer is mounted onto a mower deck of a lawn mower. The trimming unit is connected with the arm assembly while the limit switch is oppositely positioned of the trimming unit across the arm assembly. The rod assembly is connected with the arm assembly in between the trimming unit and the limit switch. The rod assembly moves the attachable trimmer in between an expanded position and a retracted position upon the user's discretion. The trimming unit is only operational when the attachable trimmer is at the expanded position as the limit switch completes an electrical circuitry to electrically power the trimming unit.

Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.

Abstract: The present invention is designed to reduce running costs in refrigerant based air-conditioning, refrigeration and heating systems by using a combination of thermodynamic and hydraulic control to manage the on and off states of the compressor, which is the main energy consuming component. Thermodynamic or temperature control is used to manage comfort levels within the room or space being cooled. Hydraulic control is used to determine when the compressor has completed its useful work in delivering a supply of high-pressure liquid refrigerant. Once temperature and hydraulic conditions are satisfied the compressor can be turned off; thereby delivering a significant reduction in running costs.

Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.

Abstract: The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.

Abstract: Mobile platforms and methods may provide for an integrated circuit such as a system on chip (SoC), a first heat spreader thermally coupled to the integrated circuit and a phase change material configuration thermally coupled to the first heat spreader. The integrated circuit may include logic to operate the integrated circuit in a performance burst mode according to a duty cycle, wherein the performance burst mode causes a phase change material to enter a liquid state within a graphite matrix of the phase change material configuration.

Abstract: A device configured to detect, measure, and/or monitor physiological signals of a mammal. The device and system can detect a pulse and/or skin bioimpedance of a mammal and determine one or more physiological parameters based on the detected pulse and/or dermal bioimpedance. The device and system converts one or more physiological signals detected by the one or more sensors into one or more physiological parameters and stores the physiological parameters as electronic data, the electronic data being related to a physiological condition of the mammal.

Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.

Abstract: A patient interface device (8) includes a cushion assembly (100) that is customizable to compensate for anatomical variances from patient-to-patient and, therefore, provides an effective seal with the patient's face. The cushion assembly includes a cushion member (102) having a first side structured to engage the patient's face, and a second side disposed opposite the first side, a plurality of plate members (108, 110, 112, 114, 116), and an adjustment mechanism (120, 122, 124). The adjustment mechanism is structured to adjust the position of the plate members, thereby changing the shape of the cushion member to gener ally conform to the patient's face.

Abstract: A rotary electronic locking system for locking utility box or storage compartments installed on trucks or other vehicles, using a remote device like a remote key fob to lock and unlock the storage compartments, or by wiring the system to the vehicle's factory-installed electronic door lock system and utilizing the remote device supplied with the factory-installed electronic door lock system to lock and unlock the storage compartments. The rotary electronic locking system operates independently from the existing handles on the storage compartments. It may be used as a primary or secondary locking system, providing additional security. The system includes a rotating rod assembly with strikers, which is rotated by an electronic actuator causing the strikers to engage with or disengage from striker plates attached to the interior of the storage compartments.

Abstract: Searching for objects in a distributed version control system. A method includes accessing a single index. The single index indexes objects in a plurality of pack files. Each pack file is a single object container aggregating the content of what would otherwise be loose objects of a version control system within the single object container such that the single object container includes the aggregated content. The method further includes from the single index, determining a location of a version control system object by determining from the index which pack file from among the plurality of pack files the object is stored in, and a location in the pack file where the object is stored. The method also includes retrieving the version control system object from the pack file.

Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.