Abstract: A method and system for co-locating journaling and data storage based on write requests. A write request that includes metadata and data is received from a client. A logical storage unit for storing the metadata and the data is identified. The logical storage unit is divided into a journal partition and a volume partition. The journal partition includes a first log and a second log. Which of the first log and the second log is an active log and which of the first log and the second log is an inactive log are identified. The metadata is recorded in a first location in the active log and the data is recorded in a second location in the active log during a single I/O operation. A reply is sent to the client after the metadata and the data are recorded in the journal partition.

Abstract: Systems, methods and computer-readable media are provided for facilitating dynamic resource management. In embodiments, a candidate modification parameter indicating a candidate modification to apply to an event is obtained. In response to obtaining the candidate modification parameter, a resource collection is determined, from among a plurality of resource collections, to support the event. The resource collection can be determined based on the candidate modification parameter and a set of resource parameters associated with the resource collection. A modification to be applied to modify the event is identified in accordance with the candidate modification parameter. Thereafter, an event modification is initiated by instructing at least one resource management software to modify event data associated with the event so as to correspond to the event modification.

Abstract: This invention relates to compounds of general Formula (I) and pharmaceutically acceptable salts thereof, in which R1, R2, R2A, R2B, R3, R4, R5A, R5B, R6, R7, R8, R9, p, q and r are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.

Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.

Abstract: A method is provided for applying porous carbonaceous particles to soil for purpose of cultivating plants having roots, where at least 95% of the porous carbonaceous particles have a particle size less than or equal to 10 mm. The method incorporates the porous carbonaceous particles into the soil surrounding the plant roots at a depth of between 0-24 inches from the soil surface, where the porous carbonaceous particles are positioned in the area surrounding the roots of the plants at a ratio of between 1:999 to 1:1 porous carbonaceous particles to soil.

Abstract: Techniques are provided for multi-tier write allocation. A storage system may store data within a multi-tier storage environment comprising a first storage tier (e.g., storage devices maintained by the storage system), a second storage tier (e.g., a remote object store provided by a third party storage provider), and/or other storage tiers. A determination is made that data (e.g., data of a write request received by the storage system) is to be stored within the second storage tier. The data is stored into a staging area of the first storage tier. A second storage tier location identifier, for referencing the data according to a format utilized by the second storage tier, is assigned to the data and provided to a file system hosting the data. The data is then destaged from the staging area into the second storage tier, such as within an object stored within the remote object store.

Abstract: A tubing assembly for use with a patient interface device includes a manifold portion structured to be coupled to a conduit carrying a flow of breathing gas and a number of tubular portions. Each tubular portion extends from the manifold portion to a distal end which is structured to be coupled to the patient interface device. Each tubular portion is structured to communicate the flow of breathing gas from the manifold portion to the patient interface device. Each tubular portion comprises an adjustment element which provides for a characteristic of the tubular portion to be selectively varied.

Abstract: Techniques are provided for remote object store error handling. A storage system may store data within one or more tiers of storage, such as a local storage tier (e.g., solid state storage and disks maintained by the storage system), a remote object store (e.g., storage provided by a third party storage provider), and/or other storage tiers. Because the remote object store may not provide the same data consistency and guarantees that the storage system provides for clients such as through the local storage tier, additional validation is provided by the storage system for the remote object store. For example, when data is put into an object of the remote object store, a verification get operation is performed to read and validate information within a header of the object. Other verifications and checks are performed such as using a locally stored metafile to detect corrupt or lost metadata and/or objects.

Abstract: A representation of a calendar view is rendered on a user interface (UI). The calendar view is indicative of one or more calendar days comprising a time span including a plurality of sequential time slots. A representation of a scheduled meeting is rendered in at least one of the sequential time slots. The scheduled meeting is rendered without an icon or button operative to provide an interactive control to join the scheduled meeting. In response to determining that the scheduled meeting has started, the representation of the scheduled meeting is converted to a live meeting object and the representation of the scheduled meeting is replaced with the converted live meeting object. The live meeting object renders a live video or audio output of the scheduled meeting.

Abstract: A representation of a calendar view is rendered on a user interface (UI), the calendar view indicative of one or more calendar days comprising a time span including a plurality of sequential time slots. A representation of a calendar event is rendered that is indicative of a scheduled meeting in at least one of the sequential time slots. The scheduled meeting is rendered without an icon or button operative to provide an interactive control to join the scheduled meeting. In response to determining that a scheduled meeting has started, the representation is updated by adding a status indication that is indicative of a current status of the scheduled meeting. The current status is provided without joining the scheduled meeting.

Abstract: A valve arrangement (60) is for a patient interface device (10) having a frame portion (16). The valve arrangement includes a valve member (36) having a coupling portion (44) and a blocking portion (46) extending from the coupling portion. The coupling portion of the valve member is structured to be coupled to the frame portion. The blocking portion is structured to move between a first position and a second position. The valve arrangement further includes a guard member (40) having a coupling portion (48) and a protecting portion (50) extending from the coupling portion of the guard member. The coupling portion of the guard member is structured to be coupled to the frame portion. When the blocking portion of the valve member moves from the first position toward the second position, the blocking portion moves toward the protecting portion of the guard member.

Abstract: This invention relates to encapsulated workflow reagents comprising an encapsulating material and a workflow reagent encapsulated within the encapsulating material for sample and workflow preparation prior to chromatographic, spectroscopic or other analytical systems, use thereof, and devices comprising the same.

Abstract: Techniques are provided for storage tier verification checks. A determination is made that a mount operation of an aggregate of a set of volumes stored within a multi-tier storage environment has completed. A first metafile and a second metafile are maintained to track information related to the storage of objects of a volume of the aggregate within a remote object store that is a tier of the multi-tier storage environment. A distributed verification is performed between the first metafile and the second metafile to identify an inconsistency. Accordingly, the first metafile and the second metafile are reconciled to address the inconsistency so that storage information within the first metafile and the second metafile are consistent.

Abstract: The invention provides a method for calculating an end-diastolic pressure-volume relationship. The method includes obtaining a cardiac input representing a region of interest, wherein the region of interest comprises a left ventricle and a left atrium of a subject. An end of diastasis volume of the left ventricle is then determined based on the cardiac input, wherein diastasis is a stage of diastole during a heart cycle before atrial contraction. Further, an end of diastasis pressure in the left atrium is determined based on the cardiac input and a linearized ventricular pressure-volume relationship is generated based on the end of diastasis volume of the left ventricle and the end of diastasis pressure in the left atrium. An end-diastolic pressure-volume relationship is then determined based on an end-diastolic volume of the left ventricle and the linearized ventricular pressure-volume relationship.

Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.

Abstract: A tubing assembly for use with a patient interface device includes a manifold portion structured to be coupled to a conduit carrying a flow of breathing gas and a number of tubular portions. Each tubular portion extends from the manifold portion to a distal end which is structured to be coupled to the patient interface device. Each tubular portion is structured to communicate the flow of breathing gas from the manifold portion to the patient interface device. Each tubular portion comprises an adjustment element which provides for a characteristic of the tubular portion to be selectively varied.

Abstract: The invention provides a method for obtaining a physiological measure from a subject, in particular a P-V loop. The method includes obtaining a numerical model of a cardiac system and obtaining, in a non-invasive manner, physiological data from the subject. The numerical model is then updated based on the physiological data. The physiological data is then provided to the updated numerical model and a physiological measure is derived based on an output of the updated numerical model, wherein the physiological measure includes a P-V loop.

Abstract: Techniques are provided for remote object store error handling. A storage system may store data within one or more tiers of storage, such as a local storage tier (e.g., solid state storage and disks maintained by the storage system), a remote object store (e.g., storage provided by a third party storage provider), and/or other storage tiers. Because the remote object store may not provide the same data consistency and guarantees that the storage system provides for clients such as through the local storage tier, additional validation is provided by the storage system for the remote object store. For example, when data is put into an object of the remote object store, a verification get operation is performed to read and validate information within a header of the object. Other verifications and checks are performed such as using a locally stored metafile to detect corrupt or lost metadata and/or objects.

Abstract: Updating user-specific instances of a second application for individual users of a group based on a data file for the second application being shared via a collaboration object that corresponds to the group within a first application. The instances of the second application present each individual user with their own custom user experience that is configured to provide access to specific content based on object permissions data. An application extension is executable, by the first application, to extend content editing functionalities of the second application into the collaboration object. Responsive to specific content being associated with the collaboration object via the application extension, each of the instances of the second application may be automatically updated to provide direct access to the specific content. Thus, each user within the group defined for collaboration object can access the data file via the collaboration object and their own instance of the second application.

Abstract: Systems, methods and computer-readable media are provided for receiving, from one or more first computing devices associated with a first entity, an indication to suspend an event for an outbound resource that is associated with a first resource indicator that is stored in a first data file in a first resource management software. A second indication to suspend the event is determined to be received from one or more second devices associated with a second entity utilizing a second resource management software. The second indication to suspend the event indicates a modification to both the first data file associated with the first resource management software and a second data file associated with the second resource management software.