Abstract: Described herein is a computer implemented method. The method includes receiving a user input selecting a deformable text shape that is defined by shape data that includes path data, slice data, viewbox data, and textbox data. A further user input that resizes the viewbox of the deformable text shape is received, and in response resized shape data is calculated by calculating resized path data and resized textbox data. A resized deformable text shape is then displayed in accordance with the resized shape data.

Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: A tool arrangement for forming a tunnel in a vertebra to perform nerve ablation includes a tamp having a distal end portion that includes a tip for creating the tunnel in the vertebra and a curvable portion to direct the tip along a curved path within the vertebra; a first cannula including a cannula body that is straight along an entire length of the cannula body and configured to receive the curvable portion of the tamp and straighten the curvable portion; and a tool hub including a stationary cannula attachment coupled to the first cannula and a movable head coupled to the tamp and configured to move toward or away from the stationary cannula attachment to extend or retract, respectively, the curvable portion of the tamp from or into, respectively, the first cannula.

Abstract: A breathing assistance apparatus and method of controlling a breathing assistance apparatus is disclosed. Particularly, the breathing assistance apparatus is controlled such that it has a drying cycle to enable drying of the tubing that supplies gases to a user and prevent the harbouring of pathogens within the tube. The drying cycle is preferably operated automatically by internal controllers in the apparatus. However, it may be manually activated by pressing a button on the apparatus. The drying cycle is preferably activated at the end of a user's treatment session.

Abstract: Provided are systems and methods for producing seamless woven materials that are variable in each of their 3 dimensions. The systems and methods generally operate by altering heddle positions independently to impart three dimensional structure to a woven fabric. Weft yarn is woven into a set of warp yarns that have been individually raised or lowered along a particular cross section, essentially locking the weave into an intended 3 dimensional form.

Abstract: Techniques are disclosed for facilitating disabling an alarm in response to particular types of activity-indicative data. More specifically, activity-indicative data (e.g., measurements obtained by an electronic device) can be detected prior to a preset alarm time. Upon determining, based on the activity-indicative data, that a wakefulness condition is satisfied, the alarm can be disabled such that the alarm stimuli is not to be presented at the preset alarm time.

Abstract: Systems and methods for operating a robotic system. The methods comprise: inferring, by a computing device, a first heading distribution for the object from a 3D point cloud; obtaining, by the computing device, a second heading distribution from a vector map; obtaining, by the computing device, a posterior distribution of a heading using the first and second heading distributions; defining, by the computing device, a cuboid on a 3D graph using the posterior distribution; and using the cuboid to facilitate driving-related operations of a robotic system.

Abstract: The gases temperature supplied to a patient when the patient is undergoing treatment such as oxygen therapy or positive pressure treatment for conditions such as Obstructive Sleep Apnea (OSA) or Chronic Obstructive Pulmonary Disease (COPD) is often measured for safety and to enable controlling of the humidity delivered to the patient. The invention disclosed is related to measurement of properties, particularly temperature (thermistor), of gases flowing through a heated tube, supplying gases to a patient, which utilises the heating wire within the tube.

Abstract: A mask 100 configured to substantially surround an opening of a patient's airway. The mask has a mask body 101 comprising a filter 103 configured to filter a fluid from a patient facing side of the mask to a non-patient facing side 105 of the mask, wherein the non-patient facing side faces an ambient environment AE. The mask has an interfacing feature 121 configured to, in use, interface with a patient interface 10100, 10100? provided on the patient 10020.

Abstract: The gases temperature supplied to a patient when the patient is undergoing treatment such as oxygen therapy or positive pressure treatment for conditions such as Obstructive Sleep Apnea (OSA) or Chronic Obstructive Pulmonary Disease (COPD) is often measured for safety and to enable controlling of the humidity delivered to the patient. The invention disclosed is related to measurement of properties, particularly temperature (thermistor), of gases flowing through a heated tube, supplying gases to a patient, which utilises the heating wire within the tube.

Abstract: A system and method produce industrial hydrocarbons and other molecules in three coordinated reactors using nuclear process heat. A nuclear reactor generates heat via a nuclear process, and this heat is physically carried to one or both of the other reactors via a thermal medium. A gasification reactor uses the nuclear heat for a gasification process that converts biomass, e.g. cellulose or other polysaccharides, into gaseous hydrogen and carbon monoxide (i.e. syngas). The gasification process may be anaerobic, without requiring addition of purified or atmospheric oxygen or consumption of input biomass to provide the process heat. The syngas is carried to a Fischer-Tropsch reactor for conversion into desired output molecules, such as aviation or diesel fuel or carbon fibers, according to a selected chemical process.

Abstract: A school bus stop arm and drive unit therefor are disclosed. The stop arm includes a stop sign and a drive unit for moving the stop sign between a retracted position and a deployed position. In some embodiments the stop sign is illuminated. In some embodiments the drive unit includes a controller.

Abstract: An apparatus includes an interface to a device-under-test (DUT), an interface to a rack of cable holders, and a control circuit. Each cable holder is configured to raise or lower respective cable. The control circuit is configured to determine an internal configuration of the DUT and, based upon an internal configuration of the DUT, identify a plurality of cables to be used in testing the DUT. The control circuit is configured to cause the rack of cable holders to actuate a plurality of the cable holders associated with the identified plurality of cables to raise or lower the cable holders associated with the identified plurality of cables.

Abstract: The disclosure provides compositions comprising multi-specific compounds, including a compound that targets a phosphatase and a receptor tyrosine kinase agonist. Also provided are methods for the treatment of conditions associated with angiogenesis, comprising administering a multi-specific compound that targets a phosphatase and a receptor tyrosine kinase agonist.

Abstract: An apparatus for the supply of humidified gases to a patient is disclosed that comprises a gases supply passage downstream of a humidified gases supply, and upstream of a patient in use, where at least one sensor is embedded in or located on the outside of the wall of the passage. In preferred forms the wall of the passage divides the sensor(s) from a flow of gases in the passage. In use, a controller receives an output of the sensor(s) and derives from the output of the sensor(s) an estimation of a property of gases flowing through the passage or provides a control output to the humidified gases supply according to the output of the sensor(s).

Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for eye conditions associated with angiogenesis, for example, intraocular pressure, ocular hypertension, and glaucoma.

Abstract: This invention relates to headgear and a patient interface, or components of a headgear or patient interface, such as a nasal cannula. In one embodiment is a size adjustable headstrap to be provided as a headgear or a part thereof, in another is a portion of a headstrap or component for association therewith in which the portion or component facilitates improved location of the strap upon a user's face, in another embodiment is a system for encapsulating or covering a connector from contact with a user's face or facial skin, in another embodiment is a face mount part or body for a patient interface of a particular configuration, and in yet a further embodiment is a gases flow manifold for delivering of gases to a patient interface of a particular configuration for improved patient comfort.

Abstract: A school bus stop arm and drive unit therefor are disclosed. The stop arm includes a stop sign and a drive unit for moving the stop sign between a retracted position and a deployed position. In some embodiments the stop sign is illuminated. In some embodiments the drive unit includes a controller.