Abstract: Embodiments relate generally to systems and methods for updating the location information for a gas detector device. A gas detector device may comprise a wireless receiver operable to receive information from one or more wireless beacons. In some cases, the wireless beacons may comprise location information. When the gas detector device receives a wireless beacon, the location information stored on the gas detector device may be updated accordingly. In some cases, the subsequent readings of the gas detector device may be associated with the updated location information. In some cases, the wireless beacons may be located at critical areas within a facility, such as entrances or exits to locations.

Abstract: The present invention provides processes for preparing a prostacyclin analog of Formula I or a pharmaceutically acceptable salt thereof, wherein R10 is a linear or branched C1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods. The processes of the present invention employ reagents (e.g., the oxidizing reagent) that are less toxic that those used in the traditional methods (e.g., oxalyl chloride). Many of the processes of the present invention generate intermediates with improved e.e. and chemical purity; thereby eliminating the need of additional chromatography steps. And, the processes of the present invention are scalable to generate commercial quantities of the final compound.

Abstract: A rotary table drive with a top plate and a bottom plate cooperating to define a bore and an adjacent sealed gear housing. A bushing adapter passes through the bore and is configured to receive a bushing to mate with a segment of polygonal drill pipe allowing rotational motion to be imparted thereto. The device includes a ring bearing having an inner ring affixed rigidly to the bushing adapter and an outer ring rigidly affixed to the bottom plate, and a drive gear within the sealed gear housing mated to the bushing adapter such that the bushing adapter is rotated in response to rotation of the drive gear. The bearing is sealed against exposure to the elements by being surrounded on all sides by a combination of the top plate, bottom plate, and bushing adapter.

Abstract: Embodiments relate generally to gas detector connectivity devices, for example a dongle, to allow for continuous communication of real-time data between a gas detector and a central station. Dongle embodiments typically comprise an IR transceiver, a processor, a wireless interface device, a power source, and a means of attachment. Such dongle embodiments, and their related methods of operation, may allow for retrofitting of legacy gas detectors to provide wireless capabilities.

Abstract: Embodiments relate generally to systems and methods for updating the location information for a gas detector device. A gas detector device may comprise a wireless receiver operable to receive information from one or more wireless beacons. In some cases, the wireless beacons may comprise location information. When the gas detector device receives a wireless beacon, the location information stored on the gas detector device may be updated accordingly. In some cases, the subsequent readings of the gas detector device may be associated with the updated location information. In some cases, the wireless beacons may be located at critical areas within a facility, such as entrances or exits to locations.

Abstract: Audio/video recorders are presented for recording audio and video of various types of proceedings, including court proceedings. In some examples, audio/video recorders may obtain case information associated with a case identifier from a case management database, and associate at least some of the case information with one or more audio channel inputs of the audio interface. In some examples, audio/video recorders may associate a speaker with an audio channel input of the audio interface, determine that an amplitude of an audio signal received at the audio channel input is above a threshold, determine a time when the amplitude of the audio signal at the audio channel was determined to be above the threshold, and generate metadata as a timeline indicating that the first speaker began speaking at the first time.

Abstract: In an illustrative embodiment, systems and methods for determining exposure include detecting, based on received data from external entities, an occurrence of a catastrophic event. Responsive to detecting the occurrence, a first matrix is generated indicating features of one or more properties within a vicinity of the catastrophic event, and a second matrix is generated representing characteristics of the catastrophic event. Using the first matrix and the second matrix, a convolution calculation matrix is calculated indicating amounts of correspondence between the first matrix and the second matrix. In real time, in response to detecting the occurrence of the catastrophic event, risk exposure information is presented to at least one remote computing system associated with at least one property of the plurality of properties, where the risk exposure data relates to the amount of correspondence between the first matrix and the second matrix in reference to the at least one property.

Abstract: Systems and methods for hydro-electric power generation are disclosed. The system includes a frame or structure positioned in a waterway or channel, with one or more hydro-transition units secured to corners of the frame. The hydro-transition units include a body of reinforced fabric for redirecting water flow towards the inlet of the frame, effectively increasing the current of the water and allowing for turbines within the frame to generate power at an increased rate. Anchors and bracket systems may secure the hydro-transition units to both the waterway and the frame, thereby allowing the body of reinforced fabric to withstanding force from water-flow within the waterway. The system includes various failsafe mechanisms for disengaging or detaching the hydro-transition units from the frame and/or anchor for reacting to high water flow or volumes (e.g., flooding).

Abstract: The present application thus provides a beverage dispensing system for combining a macro-ingredient flow and a carbonated water flow. The beverage dispensing system may include a nozzle, a carbonated water source in communication with the nozzle via a carbonated water conduit and a carbonated water recirculation conduit, a macro-ingredient source in communication with the nozzle via a macro-ingredient conduit, and a macro-ingredient pump and an air chamber in communication with the macro-ingredient conduit. The carbonated water recirculation conduit is in communication with the air chamber for heat exchange therewith.

Abstract: The present invention provides amine salts of the prostacyclin analogue of Formula I and processes for generating these amine salts.

Abstract: Embodiments relate generally to systems and methods for updating the location information for a gas detector device. A gas detector device may comprise a wireless scanner operable to receive information from one or more passive tags. In some cases, the passive tags may comprise location information. When the gas detector scans a passive tag, the location information stored on the gas detector may be updated accordingly. In some cases, the subsequent readings of the gas detector may be associated with the updated location information. In some cases, the passive tags may be located at critical areas within a facility, such as entrances or exits to locations.

Abstract: Embodiments relate generally to systems and methods for completing processes on a gas detector device using near-field communication between the gas detector device and an NFC tag. The NFC tag may communicate instructions or information to the gas detector device. The NFC tag may be located on or near a gas testing system, comprising gas deliver tube(s), gas tank(s), as well as other elements. In some embodiments, the gas detector device may comprise a single button to simplify interactions with the user.

Abstract: Systems, methods, and apparatuses for analyzing histopathology images to determine the presence of certain predetermined abnormalities. The system processes histopathology images to identify/highlight regions of interest (e.g., a region that may comprise parts of a tumor, cancerous cells, or other predetermined abnormality) for subsequent review by a pathologist or other trained professional. For example, the system may process histopathology images of H&E-stained lymph node tissue to identify potentially cancerous cells within the histopathology images.

Abstract: A rotary table drive with a top plate and a bottom plate cooperating to define a bore and an adjacent sealed gear housing. A bushing adapter passes through the bore and is configured to receive a bushing to mate with a segment of polygonal drill pipe allowing rotational motion to be imparted thereto. The device includes a ring bearing having an inner ring affixed rigidly to the bushing adapter and an outer ring rigidly affixed to the bottom plate, and a drive gear within the sealed gear housing mated to the bushing adapter such that the bushing adapter is rotated in response to rotation of the drive gear. The bearing is sealed against exposure to the elements by being surrounded on all sides by a combination of the top plate, bottom plate, and bushing adapter.

Abstract: The present invention provides processes for preparing a prostacyclin analogue of Formula I or a pharmaceutically acceptable salt thereof, wherein R10 is a linear or branched C1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods. The processes of the present invention employ reagents (e.g., the oxidizing reagent) that are less toxic that those used in the traditional methods (e.g., oxalyl chloride). Many of the processes of the present invention generate intermediates with improved e.e. and chemical purity; thereby eliminating the need of additional chromatography steps. And, the processes of the present invention are scalable to generate commercial quantities of the final compound.

Abstract: The present invention provides amine salts of the prostacyclin analogue of Formula I and processes for generating these amine salts.

Abstract: The present invention provides processes for preparing a prostacyclin analog of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R10 is a linear or branched C1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods. The processes of the present invention employ reagents (e.g., the oxidizing reagent) that are less toxic that those used in the traditional methods (e.g., oxalyl chloride). Many of the processes of the present invention generate intermediates with improved e.e. and chemical purity; thereby eliminating the need of additional chromatography steps. And, the processes of the present invention are scalable to generate commercial quantities of the final compound.

Abstract: The present invention provides amine salts of the prostacyclin analogue of Formula I and processes for generating these amine salts.

Abstract: Embodiments relate generally to systems and methods for indicating when a gas detector is out of compliance. A Bluetooth Low Energy (BLE) enabled wireless gas-detector may allow for an advertisement packet to be transmitted from the gas detector. This advertisement packet may contain information about the gas detector to allow remote auditing from any BLE enabled remote listening device. This auditor device may be in the form of a mobile device, such as a cell phone or tablet, a fixed location auditor device, or any other BLE enabled device.

Abstract: The present invention provides processes for preparing a prostacyclin analogue of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R10 is a linear or branched C1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods. The processes of the present invention employ reagents (e.g., the oxidizing reagent) that are less toxic that those used in the traditional methods (e.g., oxalyl chloride). Many of the processes of the present invention generate intermediates with improved e.e. and chemical purity; thereby eliminating the need of additional chromatography steps. And, the processes of the present invention are scalable to generate commercial quantities of the final compound.