Patents by Inventor Klaus Ditrich

Klaus Ditrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120135476
    Abstract: Process for preparing N-heterocyclic optically active alcohols of the formula I by reduction of the corresponding ketone, where the reduction is carried out using a dehydrogenase having the polypeptide sequence SEQ ID NO:2 or NO:4, or using a polypeptide sequence where, compared to SEQ ID NO:2 or NO:4, up to 25% of the amino acid residues are modified by deletion; insertion, substitution or a combination thereof.
    Type: Application
    Filed: November 23, 2011
    Publication date: May 31, 2012
    Applicant: BASF SE
    Inventors: NINA SCHNEIDER, MELANIE BONNEKESSEL, MICHAEL BREUER, JÜRGEN DÄUWEL, KLAUS DITRICH, ULRICH KARL, TOBIAS STÄB
  • Publication number: 20120123155
    Abstract: The present invention relates to a method for the enzymatic hydroamination of C—C double bonds catalyzed by enzymes structurally and/or functionally related to phenylalanine ammonia lyase (PAL) isolated from microorganisms of Petroselinum crispum, Rhodoturula glutinis and/or functional active derivatives thereof.
    Type: Application
    Filed: July 27, 2010
    Publication date: May 17, 2012
    Applicant: BASF SE
    Inventors: Bernhard Hauer, Nina Schneider, Dejana Drew, Klaus Ditrich, Nick Turner, Bettina M. Nestl
  • Publication number: 20110275855
    Abstract: The present invention relates to a process for separating an enantiomer mixture of (R)- and (S)-3-amino-1-butanol optionally protected on the oxygen atom, and to a process for preparing essentially enantiomerically pure (R)-3-amino-1-butanol which optionally bears a protecting group on the oxygen atom.
    Type: Application
    Filed: January 15, 2010
    Publication date: November 10, 2011
    Applicant: BASF SE
    Inventors: Klaus Ditrich, Michael Bartsch, Harald Winsel
  • Patent number: 8008062
    Abstract: A method for preparing optically active methyl 4-(1-ammoniumethyl)benzoate sulfate by reacting racemic methyl 4-(1-aminoethyl)benzoate with an acylating agent in the presence of a lipase to give methyl 4-(1-aminoethyl)benzoate and subsequently precipitating methyl 4-(1-ammoniumethyl)benzoate sulfate by adding sulfuric acid.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: August 30, 2011
    Assignee: BASF SE
    Inventors: Klaus Ditrich, Harald Winsel, Dominique Moulin
  • Patent number: 7968328
    Abstract: The invention relates to a method for the enantioselective N-acylation of aminoalkylphenols, and to a method for producing enantiomer-pure compounds of formulae (I-S) and/or (I-R).
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: June 28, 2011
    Assignee: BASF SE
    Inventor: Klaus Ditrich
  • Patent number: 7829702
    Abstract: A process for preparing optically active trans-2,6-dimethylmorpholine by (i) reacting racemic trans-2,6-dimethylmorpholine with D-mandelic acid, (ii) removing the salt formed from D-mandelic acid and one enantiomer of trans-2,6-dimethylmorpholine from the other enantiomer of trans-2,6-dimethylmorpholine and (iii) isolating the desired optically active trans-2,6-dimethylmorpholine.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: November 9, 2010
    Assignee: BASF SE
    Inventors: Klaus Ditrich, Frank Haese
  • Publication number: 20100240928
    Abstract: The invention relates to a process for the preparation of (S)-2-amino-1-propanol (L-alaminol) from (S)-1-methoxy-2-propylamine via the hydrochloride of (S)-2-amino-1-propanol and subsequent work-up.
    Type: Application
    Filed: December 10, 2008
    Publication date: September 23, 2010
    Applicant: BASF SE
    Inventors: Olaf Kutzki, Klaus Ditrich, Michael Bartsch
  • Publication number: 20100209980
    Abstract: The invention relates to a method for the enantioselective N-acylation of aminoalkylphenols, and to a method for producing enantiomer-pure compounds of formulae (I-S) and/or (I-R).
    Type: Application
    Filed: June 19, 2006
    Publication date: August 19, 2010
    Applicant: BASF Aktiengesellschaft
    Inventor: Klaus Ditrich
  • Publication number: 20090280544
    Abstract: The present invention relates to a method for the enantioselective acylation of trans-2-benzyloxycyclohexylamine or cis-2-benzyloxycyclohexylamine, according to which an enantiomer mixture of 2-benzyloxycyclohexylamine is reacted with an acylation agent in the presence of a hydrolase. The invention also relates to a method for producing optically active trans-stereoisomers of 2-benzyloxycyclohexylamine.
    Type: Application
    Filed: September 12, 2007
    Publication date: November 12, 2009
    Applicant: BASF SE
    Inventors: Klaus Ditrich, Ute Reuther, Michael Bartsch
  • Publication number: 20090012289
    Abstract: A process for preparing optically active trans-2,6-dimethylmorpholine by (i) reacting racemic trans-2,6-dimethylmorpholine with D-mandelic acid, (ii) removing the salt formed from D-mandelic acid and one enantiomer of trans-2,6-dimethylmorpholine from the other enantiomer of trans-2,6-dimethylmorpholine and (iii) isolating the desired optically active trans-2,6-dimethylmorpholine.
    Type: Application
    Filed: December 18, 2006
    Publication date: January 8, 2009
    Applicant: BASF SE
    Inventors: Klaus Ditrich, Frank Haese
  • Publication number: 20080305530
    Abstract: A method for preparing optically active methyl 4-(1-ammoniumethyl)benzoate sulfate by reacting racemic methyl 4-(1-aminoethyl)benzoate with an acylating agent in the presence of a lipase to give methyl 4-(1-aminoethyl)benzoate and subsequently precipitating methyl 4-(1-ammoniumethyl)benzoate sulfate by adding sulfuric acid.
    Type: Application
    Filed: December 19, 2006
    Publication date: December 11, 2008
    Inventors: Klaus Ditrich, Harald Winsel, Dominique Moulin
  • Patent number: 7358396
    Abstract: A process for preparing optically active amines, a process for preparing racemic amines which can be resolved using optically active carboxylic acids or enzymes, and racemic and optically active amines and optically active amides are described.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: April 15, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Klaus Ditrich, Wolfgang Siegel
  • Publication number: 20080073221
    Abstract: A process for the regioselective cleavage of secondary amines or amides is described.
    Type: Application
    Filed: February 14, 2006
    Publication date: March 27, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Zeynep Yilmaz, Ulrich Griesbach, Klaus Ditrich
  • Patent number: 7078226
    Abstract: A process for preparing optically active amines, a process for preparing racemic amines which can be resolved using optically active carboxylic acids or enzymes, and racemic and optically active amines and optically active amides are described.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: July 18, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Klaus Ditrich, Wolfgang Siegel
  • Publication number: 20060135538
    Abstract: 7-(R)-Aminotriazolopyrimidines of the formula I where the substituents and the index are as defined below: R1 is hydrogen or methyl; R2 is methyl; R3 is C2-C1o-alkyl, C1-C4-alkoxymethyl, C3-C1o-cycloalkyl; R4 is halogen, Cl-C4-alkyl, C1-C4-haloalkyl or Cl-C4-alkoxy; n is a number from 1 to 5; Y is halogen, cyano, Cl-C4-alkyl or Cl-C4-alkoxy; where * is a center of chirality in the R configuration, processes for preparing these compounds, compositions comprising them and their use for controlling harmful fungi are described.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 22, 2006
    Inventors: Jordi Tormo Blasco, Klaus Ditrich, Hubert Sauter, Oliver Cullmann, Markus Gewehr, Wassilios Grammenos, Bernd Muller, Thomas Grote, Andreas Gypser, Joachim Rheinheimer, Ingo Rose, Peter Schafer, Frank Schieweck, Eberhard Ammermann, Siegfried Strathmann, Gisela Lorenz, Reinhard Stierl
  • Publication number: 20060122429
    Abstract: A process for preparing optically active amines, a process for preparing racemic amines which can be resolved using optically active carboxylic acids or enzymes, and racemic and optically active amines and optically active amides are described.
    Type: Application
    Filed: January 9, 2006
    Publication date: June 8, 2006
    Inventors: Klaus Ditrich, Wolfgang Siegel
  • Patent number: 6855718
    Abstract: A 7-(R)-Aminotriazolopyrimidines of formula I where the substituents and index are as defined below: R1 is hydrogen or methyl; R2 is methyl; R3 is C2-C10-alkyl, C1-C4-alkoxymethyl, C3-C10-cycloalkyl; Y is halogen, cyano, C1-C4-alkyl or C1-C4-alkoxy; where * is a center of chirality in the R configuration, processes for their preparation, compositions comprising them and their use for controlling harmful fungi.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: February 15, 2005
    Assignee: BASF Aktiengesellschaft
    Inventors: Jordi Tormo i Blasco, Klaus Ditrich, Hubert Sauter, Oliver Cullmann, Markus Gewehr, Wassilios Grammenos, Bernd Müller, Thomas Grote, Andreas Gypser, Joachim Rheinheimer, Ingo Rose, Peter Schäfer, Frank Schieweck, Eberhard Ammermann, Siegfried Strathmann, Gisela Lorenz, Reinhard Stierl
  • Publication number: 20040110771
    Abstract: The invention relates to 7-(R) aminotriazolopyrimidines of formula (I), in which the substituents and index have the following definitions: R1 represents hydrogen or methyl; R2 represents methyl; R3 represents C2-C10 alkyl, C1-C4 alkoxymethyl, or C3-C10 cycloalkyl; R4 represents halogen, C1-C4 alkyl, C1-C4 haloalkyl or C1-C4 alkoxy; n represents a number between 1 and 5; Y represents halogen, cyano, C1-C4 alkyl or C1-C4 alkoxy; whereby * is a chirality centre with an R-configuration. The invention also relates to a method for producing said compounds, to agents containing the compounds and to the use thereof for combating harmful fungi.
    Type: Application
    Filed: May 12, 2003
    Publication date: June 10, 2004
    Inventors: Jordi Tormo i Blasco, Klaus Ditrich, Hubert Sauter, Oliver Cullmann, Markus Gewehr, Wassilios Grammenos, Bernd Muller, Thomas Grote, Andreas Gypser, Joachim Rheinheimer, Ingo Rose, Peter Schafer, Frank Schieweck, Eberhard Ammermann, Siefried Strathmann, Gisela Lorenz, Reinhard Stierl
  • Patent number: 6747177
    Abstract: A process for the preparation of optically pure acetylenediols of the formulae R-I and S-I and their further reaction to give meso-zeaxanthin are described.
    Type: Grant
    Filed: July 16, 2003
    Date of Patent: June 8, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Hansgeorg Ernst, Klaus Henrich, Klaus Ditrich
  • Patent number: 6743954
    Abstract: A process for the preparation of optically pure acetylenediols of the formulae R-I and S-I and their further reaction to give meso-zeaxanthin are described.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: June 1, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Hansgeorg Ernst, Klaus Henrich, Klaus Ditrich