Abstract: Provided are diagnostic assays and method s of using the diagnostic assays for detecting and quantifying RGMa fragments in a sample. The methods may be used detection of the RGMa fragments to monitoring drug treatment and effectiveness of drug treatment in neurodegenerative diseases.

Abstract: The invention relates to a load cell for weight measurement with a load beam which has an overload protection. In order to achieve a cost-effective manufacture, it is provided that the overload protection has a bar, running parallel to the center plane of the load beam, which freely engages in a recess on the movable force application side of the load beam, with the result that there is an upper and a lower air gap between the bar and the force application side. In the case of an overload, the upper or the lower air gap is bridged and the force application side comes to rest against the bar, with the result that no further movement of the force application side relative to the stationary side of the load cell is possible.

Abstract: A multilayer laminated material which comprises at least one layer of glass and which has improved thermal stability is distinguished in that it comprises a lower substrate layer of a plastic, a metal or a combination of plastic and metal, an intermediate layer arranged thereon and comprising a soft material or comprising a thermoplastic, a further fibrous intermediate layer comprising plastic, which is provided with a solvent-free adhesive material, and a top layer of glass. The multilayer laminated material is suitable for the installation of glass elements in the area of the electrical, the electronics and the automotive industry and for other industrial applications.

Abstract: Engineered agents or multivalent and multispecific binding proteins capable of penetrating the cells or tissue of the blood-brain barrier (BBB) are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease.

Abstract: An exhaust gas line section, through which an exhaust gas can flow, includes a flow guiding structure, a feed unit configured to supply a liquid additive to the exhaust gas, and a permeable impingement structure, the flow guiding structure, the feed unit, and the permeable impingement structure being positioned one behind the other in the flow direction. The feed unit and the flow guiding structure are arranged and configured such that an impingement region of the liquid additive on the impingement structure overlaps the center of gravity of a flow distribution of the exhaust gas flowing through the impingement structure.

Abstract: An optoelectronic component having an outer surface facing the environment of the optoelectronic component and which is formed by a hydrophobic layer applied at least partly on a surface of the optoelectronic component.

Abstract: A housing suitable to comprise multiple electrical power cells in electrically driven motor vehicles comprises at least one lower receiving part and one upper covering part. Both parts fit together and create inside a hollow space. Both parts are prepared from a multilayered material comprising at least one support layer of thermoplastic polymer and at least one cover layer of metal adhering to each other. Such housing is perfectly suitable to protect the power cells inside against mechanical damage and against the influence of fire and/or electromagnetic radiation.

Abstract: A solvent-free multilayer laminated material comprises a lower substrate layer comprising a thermoplastic polymer or a mixture of thermoplastic polymers, an intermediate layer arranged thereon and comprising a flexible material, a further fibrous intermediate layer comprising plastic, which is provided with an adhesive material and an upper layer comprising metal, comprising plastic or comprising wood or wood-like materials. It does surprisingly not show any deformation even under exposure to temperatures of about 80° C. over a period of up to 40 days and can be used for the production of articles of furniture, floor coverings, wall panels or shaped articles for the electrical, construction or automotive industry.

Abstract: In one aspect, there is disclosed a process for enabling communication of a communication device over a spectrum including the steps of: providing a communication device, detecting available analog signals, analyzing the detected analog signals, connecting to a highest energy signal, and repeating these steps.

Abstract: A housing for an optical component is provided in various embodiments. The housing has a leadframe section and a mold compound. The leadframe section is formed from an electrically conductive material and has a first side and a second side facing away from the first side. On the first side, the leadframe section has at least one first receiving region for receiving the optical component and/or at least one contact region for electrically contacting the optical component. The leadframe section has at least one trench which is formed in the leadframe section on the first side thereof alongside the receiving region and/or the contact region. The leadframe section is embedded in the mold compound. The mold compound has at least one receiving recess in which the first receiving region and/or the contact region and the trench are arranged.

Abstract: In an example embodiment a market data management system allows users to track information regarding commodities. A representative market data management system comprises physical commodity objects including a plurality of fields that describe a real world commodity, market identifier objects including market identifier codes, and contract specification objects including a plurality of fields that describe a derivative contract specification for a particular commodity traded at a particular commodity market. In the data model, a one to many relationship may exist for a physical commodity object and contract specification objects (e.g., a given commodity may be traded according to different derivative contract specifications). The data model may also allow a many to many relationship between contract specification objects and market identifier objects (e.g.

Abstract: A system receives a commodity identification, a curve type, and a curve category. The system also receives an interpolation identification, an extrapolation identification, a read procedure, and a maximum number of days for a readback. The system further receives contract data, the contract data including a market identifier code, a derivative contract specification (DCS) identification, and a price type. The system uses the contract data to generate a commodity curve based on DCS, and displays the commodity curve based on DCS on an electronic display unit.

Abstract: A device includes a pipeline section for an exhaust gas flow. The pipeline section has an inlet end, an outlet end, a rectilinear section and a protuberance having an opening for installing a metering device for a liquid additive (in particular urea/water solution) in the rectilinear section. The protuberance has a height and an extent and the extent is at least twice as large as the height. At least one respective disk-shaped honeycomb body is disposed at each of the inlet end and the outlet end. A central axis of the opening is oriented toward one of the disk-shaped honeycomb bodies. A motor vehicle having the device is also provided.

Abstract: The invention relates to an optoelectronic component, having —a carrier (1) comprising a first main surface (Ia), —at least one optoelectronic semiconductor chip (2) having no substrate, and —a contact metallization (3a, 3b), wherein —the carrier (1) is electrically insulating, —the at least one optoelectronic semiconductor chip (2) is fastened to the first main surface (Ia) of the carrier (1) by means of a bonding material (4), particularly a solder material, —the contact metallization (3a, 3b) covers at least one area of the first main surface (Ia) free of the optoelectronic semiconductor chip (2), and —the contact metallization (3a, 3b) is electrically conductively connected to the optoelectronic semiconductor chip (2).

Abstract: An optoelectronic component having an outer surface facing the environment of the optoelectronic component and which is formed by a hydrophobic layer applied at least partly on a surface of the optoelectronic component.

Abstract: A method for producing luminous means proposes providing a carrier serving as a heat sink, said carrier comprising a planar chip mounting region. The planar chip mounting region is structured for the purpose of producing a first partial region and at least one second partial region. In this case, the first partial region has a solder-repellent property after structuring. Afterward, a solder is applied to the planar chip mounting region, such that said solder wets the at least one second partial region. At least one optoelectronic body is fixed into the at least one second partial region with the solder at the carrier. Finally, contact-connections are formed for the purpose of feeding electrical energy to the optoelectronic luminous body.

Abstract: Object differentiation used in the context of complex financial instruments and financial instrument management software is described. A computer-implemented method for the management of complex financial instruments using object differentiation is described. A processor may parse a data object stored on a computer-readable storage medium into a plurality of subparts. The data object may represent a single complex financial instrument. An object differentiation key may be retrieved for each of the plurality of subparts. Using at least the retrieved object differentiation keys, a key figure may be generated for each of the plurality of subparts. A list of the plurality of subparts and the generated key figures may be displayed.

Abstract: A swiveling device for a swiveling C-arm of an X-ray unit includes a motorized drive unit and an adapter removably attachable to the C-arm concentrically with a swiveling axis thereof. The adapter connects the C-arm to the drive unit in driving manner. The swiveling device also includes an angular position encoder for recording the swivel angle of the C-arm.

Abstract: The disclosure generally describes computer-implemented methods, computer-readable media, and computer systems for flexible exposure lifecycle management. One computer-implemented method includes defining at least one custom exposure lifecycle, wherein the at least one custom exposure lifecycle includes at least one custom exposure category and at least one custom exposure activity, receiving exposure category data associated with the at least one custom exposure category, receiving exposure activity data associated with the at least one custom exposure activity, mapping, by operation of at least one computer, the received exposure category data with one of a required set of transaction categories associated with a required exposure lifecycle, and mapping, by operation of at least one computer, the received exposure activity data with one of a required set of transaction activities associated with the required exposure lifecycle.

Abstract: Location-mapped environments that provide panoramic and immersive views of street scenes are augmented with modern data visualization displays, to communicate additional information of interest. Specifically, illumination statistics information is mapped onto building facades in the location-mapped environments. The illumination statistics information can include variations of illumination as a function of time of a day and as a function of the season. The illumination statistics information can also include direct illumination statistics information and indirect illumination statistics information. Further, the illumination statistics can be calculated for any window on a building façade to determine natural lighting through that window. The illumination statistics can be employed, for example, to aid users in selection of real estate properties for rental or purchase.