Abstract: A method of treating a tumor or a viral disease by administering to a human the following 2?,5?-oligoadenylate analog: Wherein m is 0; n is 0 or 1; R1 is alkoxy substituted by hydroxyl, mercapto, alkylthio substituted by hydroxyl or X1—X2—X3—S—; R2, R3, R4, R5 and R6 are hydroxyl, mercapto, alkylthio substituted by hydroxyl or X1—X2—X3—S—; R7 is oxygen, sulfur, —NH—, or —O(CH2CH2O)q-, wherein q is 2 to 6, or oxyalkyleneoxy; R8 is hydrogen or a 5?-phosphorylated oligonucleotide which has one hydroxyl removed from the 5?-phosphoric acid; E1 is K2; E2 is K1; E3 is K2 or K3 and E4 is K1, K2 or K3; K1 is K2 is K3 is B is adeninyl; A is alkylene; D is alkyl or alkenyl; X1 is alkyl or phenyl; X2 is —C(?O)O—, —OC(?O)— or —C(?O)S—; and X3 is alkylene.

Abstract: A positive electrode active material includes: a complex oxide particle containing at least lithium and one or plural transition metals; and a coating layer provided in at least a part of the complex oxide particle, wherein the coating layer contains at least one element M which is different from the principal transition metal constituting the complex oxide particle and which is selected among elements belonging to the Groups 2 to 13, and at least one element X selected among phosphorus (P), silicon (Si) and germanium (Ge), and the element M and the element X show different distribution from each other in the coating layer.

Abstract: A 2-5A analog represented by the formula (1): wherein m is 0 or 1; n is 0 to 2; R1 represents an alkoxy group having from 1 to 6 carbon atoms which may be substituted, an unprotected mercapto group, a mercapto group protected by a nucleic acid synthesis protecting group, or an alkylthio group having from 1 to 4 carbon atoms which may be substituted; R2, R3, R4, R5 and R6 represent an unprotected hydroxyl group, a hydroxyl group protected by a nucleic acid synthesis protecting group, an alkoxy group having from 1 to 6 carbon atoms which may be substituted, an unprotected mercapto group, a mercapto group protected by a nucleic acid synthesis protecting group, or an alkylthio group having from 1 to 4 carbon atoms which may be substituted; R7 represents an oxygen atom, or a —O(CH2CH2O)q- group, wherein q is 2 to 6; R8 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms which may be substituted, or a 5?-phosphorylated oligonucleotide analog which has one hydroxyl group removed from the 5

Abstract: The invention relates to an adhesion assisting agent-bearing metal foil comprising a layer of an adhesion assisting agent containing an epoxy resin as an indispensable component on a metal, wherein the adhesion assisting agent layer has a thickness of 0.1 to 10 ?m. The invention also relates to a printed wiring board being a multilayer wiring board having a plurality of layers, wherein an adhesion assisting agent layer is formed between insulating layers.

Abstract: A control apparatus (100) controls the operating condition of an engine (200) comprising a valve operating apparatus (10) capable of changing valve operating characteristics of an intake valve (203) and an exhaust valve (204). This is provided with: an intake valve control device (110) for controlling the valve operating apparatus (10) to set the intake valve (203) continuously open, during a cranking operation of the engine (10); and an exhaust control device (120) for controlling the valve operating apparatus (10) to set the exhaust valve (204) continuously close, during the cranking operation.

Abstract: A fuel injection control apparatus for an internal combustion engine includes a fuel injection portion that performs each of first fuel injection for performing stratified-charge combustion, and second fuel injection for performing homogeneous-charge combustion; and an injection distribution ratio control portion that controls an injection distribution ratio. The injection distribution ratio control portion controls the injection distribution ratio to a target injection distribution ratio set based on a predetermined engine condition after start of the engine. An initial injection distribution ratio is set based on an engine condition at a time of start of the engine, and a change in the injection distribution ratio is controlled by referring to the engine condition after the start of the engine, when the injection distribution ratio is changed from the initial injection distribution ratio to the target injection distribution ratio.

Abstract: A novel plant belonging to the Stevia Rebaudiana Bertoni variety which contains at least 4 parts by weight or more of Rebaudioside A with respect to one part by weight of Stevioside, and allows a sweetener of a good quality to be easily produced from said plant or dried leaves thereof.

Abstract: The invention provides a cathode active material that includes: a particle containing a cathode material capable of absorbing and releasing an electrode reactive material; and a film that is disposed at least partially to the particle and contains a metal salt represented by a formula (1). (R1 represents a (a1+b1+c1) valent group and M1 represents a metallic element. a1, d1, e1 and n each represent an integer of 1 or more and b1 and c1 each represent an integer of 0 or more. However, b1 and c1 satisfy (b1+c1)?1.), a cathode therewith and a non-aqueous electrolyte secondary battery.

Abstract: To provide a resin composition which is advantageous not only in that the resin composition can be produced at low cost, but also in that it is unlikely to thermally expand, a prepreg, a laminate, and a wiring board. A resin composition for use in production of a laminate, the resin composition comprising an insulating resin having an aromatic ring, wherein the insulating resin having an aromatic ring has a molecular weight between crosslinking sites of 300 to 1,000 on the stage after the production of the laminate, as determined from an elastic shear modulus of the insulating resin measured at a temperature of Tg or higher.

Abstract: Directed to an insulating resin composition which comprises (A) a novolak epoxy resin having a biphenyl structure, (B) carboxylic acid-modified acrylonitrile butadiene rubber particles, (C) a triazine ring-containing cresol novolak phenolic resin, (D) a phenolic hydroxyl group-containing phosphorus compound, and (E) inorganic filler, an insulating film having a support using the same, a multilayer wiring board, and a process for producing a multilayer wiring board.

Abstract: Provided is a hair cosmetic composition containing (A) an amphipathic amide lipid, (B) a cationic surfactant or a tertiary amine type compound represented by the following formula (N): wherein, A represents a hydrogen atom or a linear or branched, saturated or unsaturated amide, (N-hydrocarbon)carbamoyl, acyloxy or hydrocarbonoxy group each having 12 to 24 carbon atoms in total, B represents a linear or branched, saturated or unsaturated C1-22 hydrocarbon group, and Z1 and Z2 each represents a C1-4 alkyl group; or a salt of the compound, and (C) a silicone; and having a pH at 25° C. of from 1 to 4.5 when diluted with water to 20 times the weight of the composition. The hair cosmetic composition of the present invention can protect hair from physical and chemical stimulation, thereby preventing split ends or broken hair, and impart hair with good feeling to the touch, for example, moist feeling, smoothness and suppleness which healthy hair inherently possesses, and has excellent storage stability.

Abstract: A fuel cell assembly has a fuel cell stack (1) provided with a polymer electrolyte membrane (2), an air electrode (4) and a fuel electrode (3); an air supply device (19) for supplying air; a fuel gas supply device (20) for supplying fuel gas, and a humidity regulation module (5) allowing movement of water from a humid air passage (6) to a dry air passage (7). The air electrode (4) is divided into an upstream air electrode (4a) and a downstream air electrode (4b). The air supplied from the air supply device (19) is supplied to the upstream air electrode (4a) after passing through the dry air passage (7). The air discharged from the upstream air electrode (4a) is supplied to the downstream air electrode (4b) after passing through the humid air passage (6).

Abstract: The invention relates to an adhesion assisting agent-bearing metal foil comprising a layer of an adhesion assisting agent containing an epoxy resin as an indispensable component on a metal, wherein the adhesion assisting agent layer has a thickness of 0.1 to 10 ?m. The invention also relates to a printed wiring board being a multilayer wiring board having a plurality of layers, wherein an adhesion assisting agent layer is formed between insulating layers.

Abstract: A method for the prevention or treatment in a mammal of a disease preventable or treatable by the pharmacologically useful antisense or antigene activity of an oligonucleotide analogue or a pharmacologically acceptable salt thereof in the body of said mammal, which method comprises administering to said mammal in need of such prevention or treatment a pharmaceutically effective amount of an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of said nucleoside units is a structure of the formula (2): wherein A is methylene; and B is an unsubstituted purin-9-yl, an unsubstituted 2-oxo-pyrimidin-1-yl or a substituted purin-9-yl; or a pharmacologically acceptable salt thereof.

Abstract: In a grinding wheel comprising a disc-like core member and a ring-shape grinding wheel layer wherein superabrasive grains selected from cubic boron nitride particles and diamond particles are contained together with aggregates in a bonding material, the aggregates are made of porous ceramics particles and have an average particle size which is in a range of 70% to 150% relative to the average particle size of the superabrasive grains, and bridges made of the bonding material are formed between the aggregates adjoining to one another or between the aggregates and the superabrasive grains adjoining to the aggregates.

Abstract: A compound of the formula (1): wherein R1 and R2 are the same or different and represent a hydrogen atom, a hydroxyl protecting group, a phosphate group, or —P(R3)R4, wherein R3 and R4 are the same or different and represent a hydroxyl group, an amino group, an alkoxy group having from 1 to 4 carbon atoms, a cyanoalkoxy group having from 1 to 5 carbon atoms or an amino group substituted by an alkyl group having from 1 to 4 carbon atoms; A represents an alkylene group having from 1 to 4 carbon atoms and B represents a purin-9-yl group, a 2-oxo-pyrimidin-1-yl group, a substituted purin-9-yl group or a substituted 2-oxo-pyrimidin-1-yl group having a substituent ? selected from the group consisting of a hydroxyl group which may be protected, an alkoxy group having from 1 to 4 carbon atoms, a mercapto group which may be protected, an alkylthio group having from 1 to 4 carbon atoms, an alkoxy group having from 1 to 4 carbon atoms, an amino group which may be protected, a mono- or di-alkylamino group which may b

Abstract: The present invention provides desks with which layout can be changed easily and accurately without disturbing the order of a work space and an entire office. The desk includes a base extending in a predetermined direction, a movable supporting member supported so as to be movable along the base, and a top board supported by the movable supporting member so as to be turnable in the horizontal direction.

Abstract: The present invention provides a desk with which flexibility of a change in the position of an optional member with respect to a base is increased, and by which the position of an optional member with respect to the base can be changed easily and accurately in accordance with the posture of a top board with respect to the base. A desk includes: a base extending in a predetermined direction; a top board capable of selecting a plurality of postures with respect to the base; an option supporting member supported so as to be movable along the base in accordance with the posture of the top board; and a panel system and a task light supported by the option supporting member.

Abstract: A probe for a gene or a primer for starting amplification comprising an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of the nucleoside units is a structure of the formula (2): wherein A represents a C1-C4 alkylene group, and B is an unsubstituted purin-9-yl group, an unsubstituted 2-oxo-pyrimidin-1-yl-group, a substituted purin-9-yl-group or a substituted 2-oxo-pyrimidin-1-yl group. Also a method for preventing or treating a disease preventable or treatable by the antisense or antigene activity of an oligonucleotide by administering the oligonucleotide analogue.

Abstract: There is provided a fuel gas supply manifold (4) which extends through a plurality of cells (1) in the stacking direction and which is adapted to introduce a fuel gas to the cells (1). There are provided a bypass passage (9) connecting the downstream end of the fuel gas supply manifold (4) to the fuel gas exhaust manifold (7), and a valve (11) for opening and closing the bypass passage (9). When starting the supply of a fuel gas to the fuel gas supply manifold (4), the valve (11) is opened, whereby most of the air in the fuel gas supply manifold (4) is driven away to the exterior through scavenging by the fuel gas by way of the bypass passage (9) without causing it to pass through the interior of the cells.