Patents by Inventor Kuei-Ying Lin

Kuei-Ying Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS
    Publication number: 20190345190
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: November 20, 2018
    Publication date: November 14, 2019
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS
    Publication number: 20190315785
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: November 19, 2018
    Publication date: October 17, 2019
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • Phosphonate analogs of HIV inhibitor compounds
    Publication number: 20180086784
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 6, 2017
    Publication date: March 29, 2018
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS
    Publication number: 20170210770
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: January 10, 2017
    Publication date: July 27, 2017
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • ANTIVIRAL COMPOUNDS
    Publication number: 20170088576
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 30, 2017
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • Phosphonate analogs of HIV inhibitor compounds
    Patent number: 9579332
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: February 28, 2017
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • Antiviral compounds
    Patent number: 9457035
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: October 4, 2016
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • ANTIVIRAL COMPOUNDS
    Publication number: 20140288294
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: February 11, 2014
    Publication date: September 25, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Constantine G. BOOJAMRA, Kuei-Ying LIN, Richard L. MACKMAN, David Y. MARKEVITCH, Oleg V. PETRAKOVSKY, Adrian S. RAY, Lijun ZHANG
  • Antiviral compounds
    Patent number: 8697861
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: April 15, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • Antiviral compounds
    Patent number: 8329926
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: July 27, 2005
    Date of Patent: December 11, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • Phosphonate analogs of HIV inhibitor compounds
    Patent number: 8318701
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: November 27, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • Phosphonate analogs of HIV inhibitor compounds
    Patent number: 7871991
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: January 18, 2011
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard Mackman, David Y. Markevitch, Oleg V. Petrakovsky, Adrian S. Ray, Lijun Zhang
  • Phosphonate inhibitors of HCV
    Patent number: 7842672
    Abstract: A compound of Formula I, Formula II, Formula III, or Formula IV: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, therapeutic compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: November 30, 2010
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, James M. Chen, Alan X. Huang, Choung U. Kim, Kuei-Ying Lin, Richard L. Mackman, David A. Oare, Jason K. Perry, Oliver L. Saunders, Sundaramoorthi Swaminathan, Lijun Zhang
  • ANTI-CANCER PHOSPHONATE ANALOGS
    Publication number: 20100022467
    Abstract: The invention is related to phosphorus substituted anti-cancer compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: September 2, 2008
    Publication date: January 28, 2010
    Inventors: Constantine G. Boojamra, Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Steven Krawczyk, Christopher P. Lee, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Peter H. Nelson, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang, Lijun Zhang
  • Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds
    Patent number: 7649015
    Abstract: Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: January 19, 2010
    Assignee: Gilead Sciences, Inc.
    Inventors: Murty N. Arimili, Xiaowu Chen, Maria Fardis, Gong-Xin He, Haolun Jin, Choung U. Kim, William A. Lee, Kuei-Ying Lin, Hongtao Liu, Richard L. Mackman, Michael L. Mitchell, Hyung-Jung Pyun, Mark Sparacino, Sundaramoorthi Swaminathan, Jianying Wang, Matthew A. Williams, Lianhong Xu, Zheng-Yu Yang, Richard H. Yu, Jiancun Zhang, Lijun Zhang
  • Therapeutic phosphonate compounds
    Patent number: 7645747
    Abstract: The invention is related to phosphorus substituted therapeutic agents, compositions containing such phosphorus substituted agents, and therapeutic methods that include the administration of such phosphorus substituted agents, as well as to processes and intermediates useful for preparing such agents.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: January 12, 2010
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Carina E. Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Manoj Desai, Maria Fardis, Craig S. Gibbs, Ralph F. Hirschmann, Alan X. Huang, Haolun Jin, Choung U. Kim, Thorsten A. Kirschberg, Steven Krawczyk, Christopher P. Lee, William A. Lee, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Peter H. Nelson, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang, Lijun Zhang
  • ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS
    Publication number: 20090247488
    Abstract: The invention is related to phosphorus substituted anti-inflammatory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: June 25, 2008
    Publication date: October 1, 2009
    Inventors: Carina Cannizzaro, James Chen, Xiaowu Chen, Aesop Cho, Lee Chong, Maria Fardis, Craig Gibbs, Ralp F. Hirschmann, Thorsten Kirschberg, Christopher P. Lee, Kuei-Ying Lin, Richard L. Mackman, Peter H. Nelson, David A. Oare, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang
  • Phosphonate Analogs of Hiv Inhibitor Compounds
    Publication number: 20090202470
    Abstract: The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 26, 2005
    Publication date: August 13, 2009
    Applicant: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Oleg V. Petrakosvsky, Adrian S. Ray, Lijun Zhang
  • NUCLEOTIDE ANALOGS
    Publication number: 20090149648
    Abstract: Nucleotide analogs characterized by the presence of an amidate linked amino acid or an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise a phosphoamidate or ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.
    Type: Application
    Filed: September 16, 2008
    Publication date: June 11, 2009
    Applicant: Gilead Sciences, Inc.
    Inventors: Norbert W. Bischofberger, Robert J. Jones, Murty N. Armilli, Kuei-Ying Lin, Michael S. Louie, Lawrence R. McGee, Ernest J. Prisbe, William A. Lee, Kenneth C. Cundy
  • Pyrimidine derivatives for labeled binding partners
    Patent number: 7511125
    Abstract: Compounds having structure (1) wherein R1 is —H a protecting group, a linker or a binding partner; and R2 and R34 are as defined in the specification. The invention also provides intermediates and methods make the structure (1) compounds, as well as methods to use the compounds as labels in diagnostic assays and to enhance binding to complementary bases.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: March 31, 2009
    Assignee: Carlsbad
    Inventors: Kuei-Ying Lin, Mark D. Matteucci