Patents by Inventor Kuei-Ying Lin

Kuei-Ying Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5414077
    Abstract: Pseudonucleosides and pseudonucleotides are useful in the synthesis of oligomers which contain these components as a means to derivatize the resulting oligonucleotide to useful substituents such as chelators, intercalators, or lipophilic compounds. In general, these pseudonucleotide components are of the formula: ##STR1## wherein each Y is independently O or S; each X is independently H, PO.sub.3.sup.-2, an activated nucleotide synthesis coupling moiety, a protecting group, a nucleoside, a nucleotide or a nucleotide sequence, or comprises a solid support;F is a functional group capable of linking an additional moiety or said group already reacted to effect the binding of said additional moiety;.quadrature.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: May 9, 1995
    Assignee: Gilead Sciences
    Inventors: Kuei-Ying Lin, Mark Matteucci
  • Patent number: 5214136
    Abstract: Oligonucleotide sequences modified by conjugation to at least one unsubstituted or substituted anthraquinone at other than the 5' terminus have favorable properties in enhancing hybridization to target DNA or RNA without loss of specificity and show enhanced stability to nucleases.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: May 25, 1993
    Assignee: Gilead Sciences, Inc.
    Inventors: Kuei-Ying Lin, Mark Matteucci