Abstract: Disclosed are new compounds of formula (1) exhibiting excellent activity for glucokinase, pharmaceutical compositions having the same as an active ingredient, and a method of using the same as an active ingredient for lowering blood glucose level: in which the substituents are as defined herein.

Abstract: Example embodiments relate to a method of forming a hardened porous dielectric layer. The method may include forming a dielectric layer containing porogens on a substrate, transforming the dielectric layer into a porous dielectric layer using a first UV curing process to remove the porogens from the dielectric layer, and transforming the porous dielectric layer into a crosslinked porous dielectric layer using a second UV curing process to generate crosslinks in the porous dielectric layer.

Abstract: Novel compounds exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV(DPP-IV) include those of the following formula (1) or pharmaceutically acceptable salt thereof: wherein A is a substituted or unsubstituted 1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridine, 5,6 -dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazine, 4,5-dihydro-7H-isooxazolo[3,4-c]pyridine, 3,4 -dihydroisoquinoline, 5,8-dihydropyrido[3,4-d]pyrimidine, or 6,7 -dihydro[1,3]thiazolo[4,5,c]pyridine, and B is a substituted or unsubstituted piperidin-2-one, morpholin-3-one, oxazolidin-2-one, pyrrolidin-2-one, or 1,5-dihydro-pyrrol-2-one. Methods of preparing the novel inhibitory compounds of formula (1) and pharmaceutical compositions containing the same as an active agent are disclosed.

Abstract: Disclosed herein are novel compounds of Formula (1) as defined in the specification having excellent inhibitory activity against dipeptidyl peptidase-IV (DPP-IV), methods of preparing the same and pharmaceutical compositions comprising the same as an active agent.

Abstract: The present invention relates to new compounds of formula (1) exhibiting excellent activity for glucokinase, and pharmaceutical compositions comprising the same as an active ingredient.

Abstract: The present invention relates to novel compounds exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV (DPP-IV), methods of preparing the same and pharmaceutical compositions containing the same as an active agent.

Abstract: A water jacket structure for a cylinder head and cylinder block of an automobile engine with a split cooling system adapted therein is disclosed, in which the shape of the inlet of the water jacket is altered to diminish the flow loss, and the position of the outlets for the cylinder head and the cylinder block is disposed at the same height to improve the life expectancy of the thermostat device. Water jackets are formed for the cylinder head and the cylinder block respectively and independently. An inlet is shared between the cylinder head and the cylinder block, with its cross sectional area being reduced inward, and two outlets are formed on the cylinder head respectively and independently.

Abstract: A water jacket structure for a cylinder head and cylinder block of an automobile engine with a split cooling system adapted therein is disclosed, in which the shape of the inlet of the water jacket is altered to diminish the flow loss, and the position of the outlets for the cylinder head and the cylinder block is disposed at the same height to improve the life expectancy of the thermostat device. Water jackets are formed for the cylinder head and the cylinder block respectively and independently. An inlet is shared between the cylinder head and the cylinder block, with its cross sectional area being reduced inward, and two outlets are formed on the cylinder head respectively and independently.