Patents by Inventor Lane A. Smith

Lane A. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200093962
    Abstract: Neo-cartilage constructs suitable for implantation into a joint cartilage lesion in situ and a method for repair and restoration of function of injured, traumatized, aged or diseased cartilage. The construct comprises at least chondrocytes incorporated into a support matrix processed according to the algorithm comprising variable hydrostatic or atmospheric pressure or non-pressure conditions, variable rate of perfusion, variable medium composition, variable temperature, variable cell density and variable time to which the chondrocytes are subjected.
    Type: Application
    Filed: July 30, 2019
    Publication date: March 26, 2020
    Applicants: HISTOGENICS CORPORATION, TAKAGI INDUSTRIAL CO. LTD.
    Inventors: Shuichi Mizuno, Akihiko Kusanagi, Laurence J.B. Tarrant, Toshimasa Tokuno, Robert Lane Smith
  • Patent number: 10558247
    Abstract: A system and method for heat dissipation and vibration damping of electronic devices in which an assembly is formed by one or more surfaces comprised of at least one material that is a thermally conductive plastic that combines to partially or completely enclose one or more electronic devices as a physical and thermal intermediary between the electronic devices and supporting structures.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: February 11, 2020
    Inventor: David Lane Smith
  • Publication number: 20190321451
    Abstract: The invention generally relates to systems (i.e. constructs) for repairing cartilage and methods for preparing the same that introduce a bioactive agent into a culture medium, suspension, scaffold, solution incorporated into the pores of the scaffold, or combinations thereof. The introduction of a bioactive agent promotes production of neo-cartilage (i.e. immature hyaline cartilage) in the system, both ex-vivo and in-vivo.
    Type: Application
    Filed: July 5, 2019
    Publication date: October 24, 2019
    Applicant: Histogenics Corporation
    Inventors: Laurence J.B. Tarrant, Sonya Shortkroff, Shuichi Mizuno, Akihiko Kusanagi, Toshimasa Tokuno, Robert Lane Smith
  • Patent number: 10398063
    Abstract: A system and method for cooling electronic devices disposed within the inner volume of an enclosure. The inner volume of the enclosure contains one or more single phase or multi-phase thermally conductive fluids and may contain solid or sealed hollow structures that displace and direct thermally conductive fluids.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: August 27, 2019
    Inventor: David Lane Smith
  • Publication number: 20190219311
    Abstract: An system and method for cooling of electronic equipment, for example a computer system, in a subsurface environment including a containment vessel in at least partial contact with subsurface liquid or solid material. The containment vessel may be disposed in a variety of subsurface environments, including boreholes, man-made excavations, subterranean caves, as well as ponds, lakes, reservoirs, oceans, or other bodies of water. The containment vessel may be installed with a subsurface configuration allowing for human access for maintenance and modification. Cooling is achieved by one or more fluids circulating inside and/or outside the containment vessel, with a variety of configurations of electronic devices disposed within the containment vessel. The circulating fluid(s) may be cooled in place by thermal conduction or by active transfer of the fluid(s) out of the containment vessel to an external heat exchange mechanism, then back into the containment vessel.
    Type: Application
    Filed: March 24, 2019
    Publication date: July 18, 2019
    Inventor: David Lane Smith
  • Patent number: 10240845
    Abstract: An system and method for cooling of electronic equipment, for example a computer system, in a subsurface environment including a containment vessel in at least partial contact with subsurface liquid or solid material. The containment vessel may be disposed in a variety of subsurface environments, including boreholes, man-made excavations, subterranean caves, as well as ponds, lakes, reservoirs, oceans, or other bodies of water. The containment vessel may be installed with a subsurface configuration allowing for human access for maintenance and modification. Cooling is achieved by one or more fluids circulating inside and/or outside the containment vessel, with a variety of configurations of electronic devices disposed within the containment vessel. The circulating fluid(s) may be cooled in place by thermal conduction or by active transfer of the fluid(s) out of the containment vessel to an external heat exchange mechanism, then back into the containment vessel.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: March 26, 2019
    Inventor: David Lane Smith
  • Publication number: 20190025893
    Abstract: A system and method for heat dissipation and vibration damping of electronic devices in which an assembly is formed by one or more surfaces comprised of at least one material that is a thermally conductive plastic that combines to partially or completely enclose one or more electronic devices as a physical and thermal intermediary between the electronic devices and supporting structures.
    Type: Application
    Filed: September 17, 2018
    Publication date: January 24, 2019
    Inventor: David Lane Smith
  • Publication number: 20180373887
    Abstract: A distributed storage system for the long-term storage of data objects that is implemented utilizing one or more distinct storage sites that may be comprised of system controllers and object storage systems that act in concert to embody a single distributed storage system. A system may include a one or more types and/or instances of object storage systems. A system may include witness functionality in which a trusted user and/or client acts to maintain consistent storage policies on behalf of one or more users and/or clients. A system may further include system controllers associated with logical and/or physical sites that coordinate object, user, device, and system management functionally.
    Type: Application
    Filed: September 3, 2018
    Publication date: December 27, 2018
    Inventor: David Lane Smith
  • Publication number: 20180343774
    Abstract: A system and method for cooling electronic devices disposed within the inner volume of an enclosure. The inner volume of the enclosure contains one or more single phase or multi-phase thermally conductive fluids and may contain solid or sealed hollow structures that displace and direct thermally conductive fluids.
    Type: Application
    Filed: August 6, 2018
    Publication date: November 29, 2018
    Inventor: David Lane Smith
  • Patent number: 10079042
    Abstract: A system and method for heat dissipation and vibration damping of electronic devices in which an assembly is formed by one or more surfaces comprised of at least one material that is a thermally conductive plastic that combines to partially or completely enclose one or more electronic devices as a physical and thermal intermediary between the electronic devices and supporting structures.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: September 18, 2018
    Inventor: David Lane Smith
  • Publication number: 20180256309
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Application
    Filed: May 11, 2018
    Publication date: September 13, 2018
    Applicant: Histogenics Corporation
    Inventors: Sonya Shortkroff, Laurence J.B. Tarrant, Eric J. Roos, Robert Lane Smith, Hans P.I. Claesson
  • Patent number: 10069914
    Abstract: A distributed storage system for the long-term storage of data objects that is implemented utilizing one or more distinct storage sites that may be comprised of system controllers and object storage systems that act in concert to embody a single distributed storage system. A system may include a one or more types and/or instances of object storage systems in which replicas of objects are stored in at least two of the said object storage systems. A system may further include system controllers associated with logical and/or physical sites that coordinate object, user, device, and system management functionally.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: September 4, 2018
    Inventor: David Lane Smith
  • Patent number: 10045467
    Abstract: A system and method to render inoperable electronic devices disposed with a volume of a fluid-tight sealed enclosure. Thermally conductive fluids that fill one or more volumes of said sealed enclosure may be circulated away from said sealed enclosure to an external heat exchange mechanism. The volume of the sealed container contains one or more single phase or multi-phase thermally conductive fluids and may contain solid or sealed hollow structures that conform to or occupy space between said electronic devices. Pressure balancing mechanisms are included to maintain suitable pressure of gaseous fluid in a volume of the sealed container.
    Type: Grant
    Filed: July 1, 2017
    Date of Patent: August 7, 2018
    Inventor: David Lane Smith
  • Patent number: 9993326
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: June 12, 2018
    Assignee: Histogenics Corporation
    Inventors: Sonya Shortkroff, Laurence J. B. Tarrant, Eric J. Roos, Robert Lane Smith, Hans P. I. Claesson
  • Publication number: 20180053533
    Abstract: A system and method for heat dissipation and vibration damping of electronic devices in which an assembly is formed by one or more surfaces comprised of at least one material that is a thermally conductive plastic that combines to partially or completely enclose one or more electronic devices as a physical and thermal intermediary between the electronic devices and supporting structures.
    Type: Application
    Filed: October 27, 2017
    Publication date: February 22, 2018
    Inventor: David Lane Smith
  • Publication number: 20170312391
    Abstract: A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit. A process for preparation of the double-structured implant or the stand alone secondary scaffold comprising lyophilization and dehydrothermal treatment.
    Type: Application
    Filed: June 23, 2017
    Publication date: November 2, 2017
    Applicant: Histogenics Corporation
    Inventors: Hans Peter Ingemar Claesson, Laurence J.B. Tarrant, Robert Lane Smith, Sonya Shortkroff
  • Patent number: 9804644
    Abstract: A system and method for heat dissipation and vibration damping of electronic devices in which an assembly is formed by one or more surfaces comprised of thermally conductive plastic that combine to partially or completely enclose one or more electronic devices as a physical and thermal intermediary between the electronic devices and supporting structures.
    Type: Grant
    Filed: January 2, 2016
    Date of Patent: October 31, 2017
    Inventor: David Lane Smith
  • Publication number: 20170303442
    Abstract: A system and method to render inoperable electronic devices disposed with a volume of a fluid-tight sealed enclosure. Thermally conductive fluids that fill one or more volumes of said sealed enclosure may be circulated away from said sealed enclosure to an external heat exchange mechanism. The volume of the sealed container contains one or more single phase or multi-phase thermally conductive fluids and may contain solid or sealed hollow structures that conform to or occupy space between said electronic devices. Pressure balancing mechanisms are included to maintain suitable pressure of gaseous fluid in a volume of the sealed container.
    Type: Application
    Filed: July 1, 2017
    Publication date: October 19, 2017
    Inventor: David Lane Smith
  • Publication number: 20170298320
    Abstract: A cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel-matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline-like cartilage production from chondrocytes in vivo and in vitro.
    Type: Application
    Filed: July 5, 2017
    Publication date: October 19, 2017
    Inventors: Robert Lane Smith, Laurence J.B. Tarrant, Akihiko Kusanagi, Hans P.I. Claesson
  • Publication number: 20170223870
    Abstract: An system and method for cooling of electronic equipment, for example a computer system, in a subsurface environment including a containment vessel in at least partial contact with subsurface liquid or solid material. The containment vessel may be disposed in a variety of subsurface environments, including boreholes, man-made excavations, subterranean caves, as well as ponds, lakes, reservoirs, oceans, or other bodies of water. The containment vessel may be installed with a subsurface configuration allowing for human access for maintenance and modification. Cooling is achieved by one or more fluids circulating inside and/or outside the containment vessel, with a variety of configurations of electronic devices disposed within the containment vessel. The circulating fluid(s) may be cooled in place by thermal conduction or by active transfer of the fluid(s) out of the containment vessel to an external heat exchange mechanism, then back into the containment vessel.
    Type: Application
    Filed: March 13, 2017
    Publication date: August 3, 2017
    Inventor: David Lane Smith