Patents by Inventor Lawrence B. Blyn

Lawrence B. Blyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120094274
    Abstract: The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses (e.g., swine-origin influenza A (H1N1) virus) which are members of the influenza virus family by amplification of a segment of viral nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: May 4, 2010
    Publication date: April 19, 2012
    Applicant: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, David J. Ecker, Lawrence B. Blyn, Feng Li, Thomas A. Hall, Christian Massire, Roberta Housley, Robert J. Lovari
  • Publication number: 20120064523
    Abstract: The present invention relates to portable systems and devices, and corresponding methods, for detecting bioagents. In particular, the present invention provides systems, devices, and methods that utilize one or more of a sample preparation component, sample analysis component employing broad range primers, and sample detection component.
    Type: Application
    Filed: March 30, 2010
    Publication date: March 15, 2012
    Applicant: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Steven A. Hofstadler, Rangarajan Sampath, Lawrence B. Blyn, Thomas A. Hall, Mark W. Eshoo
  • Publication number: 20120015349
    Abstract: The present invention relates generally to identification of HPV, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 23, 2011
    Publication date: January 19, 2012
    Applicant: IBIS Biosciences, Inc.
    Inventors: Rangarajan Sampath, Lawrence B. Blyn, Rachael Kreft, Thomas A. Hall, Feng Li
  • Patent number: 8084207
    Abstract: The present invention relates generally to identification of HPV, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: December 27, 2011
    Assignee: Ibis Bioscience, Inc.
    Inventors: Rangarajan Sampath, Lawrence B. Blyn, Rachael Kreft, Thomas A. Hall, Feng Li
  • Patent number: 8057993
    Abstract: The present invention provides a method for rapid identification and quantitation of bacteria by amplification of a segment of bacterial nucleic acid followed by analysis by mass spectrometry. The compositions provide for characterization of the molecular masses and base compositions of bacterial nucleic acids which are used to rapidly identify bacteria.
    Type: Grant
    Filed: April 22, 2004
    Date of Patent: November 15, 2011
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Steven A. Hofstadler, Rangarajan Sampath, Lawrence B. Blyn, Thomas A. Hall, Christian Massire
  • Publication number: 20110200997
    Abstract: The present invention relates generally to identification of enteric bacterial pathogens, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: May 29, 2009
    Publication date: August 18, 2011
    Applicant: IBIS Biosciences, Inc.
    Inventors: Sherilynn Manalili Wheeler, James C. Hannis, Feng Li, Raymond Ranken, Lawrence B. Blyn, David J. Ecker, Rangarajian Sampath, Steven A. Hofstadler
  • Publication number: 20110200985
    Abstract: The present invention relates generally to identification of herpesviruses and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 29, 2009
    Publication date: August 18, 2011
    Inventors: Rangarajan Sampath, Rachael Kreft, Lawrence B. Blyn, Feng Li, Thomas A. Hall, David J. Ecker
  • Publication number: 20110190170
    Abstract: The present invention relates generally to identification of antibiotic-resistant bacteria and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: August 4, 2011
    Inventors: Rangarajan Sampath, David J. Ecker, Robert J. Lovari, Feng Li, Lawrence B. Blyn, Thomas A. Hall
  • Publication number: 20110189687
    Abstract: The present invention relates generally to identification of members of the bacterial class Mollicutes or the bacterial genus Mycoplasma and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: August 4, 2011
    Applicant: Ibis Bioscience, Inc.
    Inventors: Rangarajan Sampath, Lawrence B. Blyn, Feng Li, Javier P. Fernandez, Thomas A. Hall
  • Publication number: 20110189676
    Abstract: The present invention relates generally to identification of fungi pathogens, and provides methods, compositions, systems and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: August 4, 2011
    Inventors: Thomas A. Hall, Mark Frinder, Raymond Ranken, Miriam Reyes, Sherilynn Manalili Wheeler, Lawrence B. Blyn, Rangarajan Sampath, David J. Ecker
  • Publication number: 20110183346
    Abstract: The present invention relates generally to the detection and identification of Neisseria, Chlamydia, and/or Chlamydophila bacterial bioagents, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Applicant: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Rachael Kreft, Javier P. Femandez, Lawrence B. Blyn
  • Publication number: 20110183344
    Abstract: The present invention relates generally to identification of strains of Clostridium difficile and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Inventors: Rangarajan Sampath, Feng Li, David J. Ecker, Robert J. Lovari, Lawrence B. Blyn, Thomas A. Hall
  • Publication number: 20110183343
    Abstract: The present invention relates generally to identification of members of the bacterial class Alphaproteobacter and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Inventors: Rangarajan Sampath, Feng Li, Robert J. Lovari, Lawrence B. Blyn, David J. Ecker
  • Publication number: 20110183345
    Abstract: The present invention relates generally to the identification of Streptococcus pneumoniae, such as antibiotic resistant Streptococcus pneumoniae, and provides methods, compositions, kits and systems useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Applicant: Ibis Biosciences, Inc.
    Inventors: Christian Massire, Rachael Kreft, Lawrence B. Blyn, David J. Ecker, Feng Li, Rangarajan Sampath
  • Publication number: 20110166040
    Abstract: The present invention relates generally to strain typing of Escherichia coli O157:H7, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: May 28, 2009
    Publication date: July 7, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: James C. Hannis, Feng Li, Rangarajan Sampath, Lawrence B. Blyn, Steven A. Hofstadler, David J. Ecker, Mark W. Eshoo
  • Publication number: 20110151437
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of adventitious contaminant viruses by molecular mass and base composition analysis.
    Type: Application
    Filed: June 1, 2009
    Publication date: June 23, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, Feng Li, Rachael Kreft, Thomas A. Hall, Lawrence B. Blyn
  • Publication number: 20110143358
    Abstract: The present invention relates generally to the field of genetic identification and quantification of tick borne pathogens and provides methods, compositions and kits useful for this purpose when combined with molecular mass or base composition analysis.
    Type: Application
    Filed: May 29, 2009
    Publication date: June 16, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, David J. Ecker, Mark W. Eshoo, Heather E. Matthews, Christopher D. Crowder, Lawrence B. Blyn
  • Publication number: 20110105531
    Abstract: The present invention provides compositions, kits and methods for rapid genotyping of strains of Mycobacterium tuberculosis by molecular mass and base composition analysis. Drug-resistant strains of Mycobacterium tuberculosis may be identified in human clinical samples and as such, provide for methods of treatment of humans infected with drug resistant strains of Mycobacterium tuberculosis.
    Type: Application
    Filed: June 23, 2008
    Publication date: May 5, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Christian Massire, Rangarajan Sampath, Lawrence B. Blyn, David J. Ecker
  • Publication number: 20110097704
    Abstract: The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses which are members of the Picornaviridae family by amplification of a segment of viral nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: January 27, 2009
    Publication date: April 28, 2011
    Applicant: IBIS Biosciences, Inc.
    Inventors: Rangarajan Sampath, Lawrence B. Blyn
  • Publication number: 20110065111
    Abstract: The present invention relates generally to identification and characterization of genotypes of Klebsiella pneumoniae and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: August 27, 2010
    Publication date: March 17, 2011
    Applicant: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Feng Li, Lawrence B. Blyn