Patents by Inventor Lawrence Loomis

Lawrence Loomis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6277399
    Abstract: A composition for treatment of bacterial infections of burns and wounds of the skin comprises an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria, and a carrier for delivering said at least one lytic enzyme to the skin. The carrier may be, but is not limited to, a liquid solution applied to a bandage.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: August 21, 2001
    Assignee: New Horizon Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Publication number: 20010014668
    Abstract: This invention relates to amino acid sequences from within a consensus peptide of the formula:
    Type: Application
    Filed: March 9, 2001
    Publication date: August 16, 2001
    Inventors: Frederick J. Cassels, Lawrence Loomis-Price
  • Patent number: 6264945
    Abstract: The present invention discloses a method and composition for the treatment of bacterial infections by the parenteral introduction of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for that bacteria and an appropriate carrier for delivering the lytic enzyme into a patient. The injection can be done intramuscularly, subcutaneously, or intravenously.
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: July 24, 2001
    Inventors: Vincent A Fischetti, Lawrence Loomis
  • Patent number: 6254866
    Abstract: A method for treatment of bacterial infections of the digestive tract is disclosed which comprises administering a lytic enzyme specific for the infecting bacteria. The lytic enzyme is preferably in a carrier for delivering said lytic enzyme. The bacteria to be treated is selected from the group consisting of Listeria, Salmonella, E. coli, Campylobacter, and combinations thereof. The carrier for delivering at least one lytic enzyme to the digestive tract is selected from the group consisting of suppository enemas, syrups, or enteric coated pills.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: July 3, 2001
    Assignee: New Horizons Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6248324
    Abstract: The present invention discloses a composition for dermatological infections by the use of a lytic enzyme in a carrier suitable for topical application to dermal tissues. The method for the treatment of dermatological infections comprises administering a composition comprising effective amount of a therapeutic agent, with the therapeutic agent comprising a lytic enzyme produced by infecting a bacteria with phage specific for that bacteria.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: June 19, 2001
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6238661
    Abstract: Compositions and methods for the prophylactic and therapeutic treatment of bacterial infections are disclosed which comprise administering to an individual an effective amount of a composition comprising an effective amount of lytic enzyme and a carrier for delivering the lytic enzyme. This method and composition can be used for the treatment of upper respiratory infections, skin infections, wounds, burns, vaginal infections, eye infections, intestinal disorders and dental problems.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: May 29, 2001
    Assignee: New Horizons Diagnostics Corp.
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6176836
    Abstract: The present invention discloses a biological sample collection kit which can be utilized to collect samples of biological origin for use in any recovery and identification method. The biological sample collection kit comprises a sterile device for collecting a sample, a collection and dispersing device for depositing and holding the sample, a device for transferring the sample, and a container for storing the sample to be tested. There may also be a labeling system for identifying the sample and for diluting the sample. The biological sample collection kit preferably contains an outer bag which holds, in a sterile environment, all of the items used in the testing procedures. Additionally, a container of collection fluid is preferably included in the sample collection kit.
    Type: Grant
    Filed: September 25, 1998
    Date of Patent: January 23, 2001
    Inventors: David Trudil, Lawrence Loomis
  • Patent number: 6056954
    Abstract: A method for the prophylactic and therapeutic treatment of bacterial infections is disclosed which comprises the treatment of an individual with an effective amount of a lytic enzyme composition specific for the infecting bacteria, with the lytic enzyme comprising an effective amount of lytic enzyme, wherein the lytic enzyme is in an environment having a pH which allows for activity of said lytic enzyme; and a carrier for delivering said lytic enzyme. This method, and composition can be used for the treatment of upper respiratory infections, skin infections, wounds, and burns, vaginal infections, eye infections, intestinal disorders and dental problems.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: May 2, 2000
    Assignee: New Horizons Diagnostics Corp
    Inventors: Vincent A. Fischetti, Lawrence Loomis
  • Patent number: 6056955
    Abstract: The present invention discloses a method and composition for the topical treatment of streptococcal infections by the use of a lysin enzyme blended with a carrier suitable for topical application to dermal tissues. The method for the treatment of dermatological streptococcal infections comprises administering a composition comprising effective amount of a therapeutic agent, with the therapeutic agent comprising a lysin enzyme produced by group C streptococcal bacteria infected with a C1 bacteriophage. The therapeutic agent can be in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: May 2, 2000
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6017528
    Abstract: The present invention relates to compositions containing Group C streptococcal phage associated lysin enzyme for the prophylactic and therapeutic treatment of Streptococcal infections, including the infection commonly known as strep throat. Methods for therapeutically and prophylactically treating such infections also are described.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: January 25, 2000
    Assignee: New Horizons Diagnostics
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 5997862
    Abstract: The present invention relates to an oral delivery system containing a group c streptococcal phage associated lysin enzyme for the prophylactic and therapeutic treatment of Streptococcal A throat infections, commonly known as strep throat.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: December 7, 1999
    Assignee: New Horizons Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 5985271
    Abstract: The present invention relates to an oral delivery system containing a group c streptococcal phage associated lysin enzyme for the prophylactic and therapeutic treatment of Streptococcal A throat infections, commonly known as strep throat.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: November 16, 1999
    Assignee: New Horizons Diagnostics Corp.
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 5736351
    Abstract: A method and device for determining the presence and concentration of total microbial contamination or the presence and concentration of a specific microbial species on a surface is described. The method consists of a means of a collection device and fluid for removing the microbes from the surface and suspending them in a fluid phase. An aliquot of the fluid phase is introduced into a disposable test ticket which allows filtration of the sample to remove extraneous substances including somatic cells, and concentration of the microbes. The total concentration of microbes is determined by adding a somatic and bacterial releasing reagent to a disposable test device which comprises a membrane containing the luminescent reagents luciferin and luciferase, and introducing the disposable test device into a luminometer that can read the luminescence from the underside.
    Type: Grant
    Filed: January 15, 1997
    Date of Patent: April 7, 1998
    Assignee: New Horizons Diagnostics Corporation
    Inventors: C. David Miller, Lawrence Loomis
  • Patent number: 5624810
    Abstract: A method for determining the presence and concentration of total microbial contamination or the presence and concentration of a specific microbial species on a surface is described. The method consists of a means of a collection device and fluid for removing the microbes from the surface and suspending them in a fluid phase. An aliquot of the fluid phase is introduced into a disposable test device which allows filtration of the sample to remove extraneous substances including somatic cells, and concentration of the microbes. The total concentration of microbes is determined by adding a bacterial releasing reagent and a luminescent reagent to the disposable test device and introducing the disposable test device into a luminometer that can read the luminescence from the side wall.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: April 29, 1997
    Assignee: New Horizons Diagnostics Corp.
    Inventors: C. David Miller, Lawrence Loomis