Abstract: The present invention relates to a pre-collapsed capacitive micro-machined transducer cell (10) comprising a substrate (12) comprising a first electrode (16), a membrane (14) comprising a second electrode (18), wherein the cell has an outer region (22) where the membrane (14) is mounted to the substrate (12) and an inner region (20) inside or surrounded by the outer region (22), wherein the membrane (14) is collapsed to the substrate (12) in a first collapsed annular-shaped region (24) located within the inner region (20).

Abstract: An ultrasound system includes a 3D imaging probe and a needle guide which attaches to the probe for guidance of the insertion of multiple needles into a volumetric region which can be scanned by the 3D imaging probe. The needle guide responds to the insertion of a needle through the guide by identifying a plane for scanning by the probe which is the insertion plane through which the needle will pass during insertion. The orientation of the insertion plane is communicated to the probe to cause the probe to scan the identified plane and produce images of the needle as it travels through the insertion plane.

Abstract: The present invention relates to Shiga toxin A Subunit derived polypeptides and cell-targeting molecules comprising amino acid substitutions which equip the polypeptides with 1) de-immunization; 2) reduced, protease-cleavage sensitivity; and/or 3) a heterologous epitope cargo(s) while retaining Shiga toxin function(s), such as, e.g., potent cytotoxicity. Certain polypeptides of the invention exhibit reduced immunogenic potential in mammals and/or are capable of delivering an epitope to an MHC class molecule of a cell in which the polypeptide is present. Certain molecules comprising a polypeptide of the invention are well-tolerated by mammals while retaining one or more of the features mentioned above.

Abstract: A matrix array probe including a transducer array and integrated circuitry coupled to the transducer elements dissipates heat generated by the array and integrated circuitry through the cover of the transducer probe. A pump in the probe connector pumps fluid through a closed loop system including inbound an outbound fluid conduits in the cable. The fluid conduits in the cable are separated by the cable electrical conductors for the probe. The heat transfer in the probe is done by a heat exchanger in the transducer backing block. Additional cooling may be provided by metal to metal contact with a chiller in the ultrasound system.

Abstract: In an embodiment of the present invention, a production light is provided to be attached to the bottom of a camera, via a threaded aperture, typically used to mount a camera to a tripod. The production light is configured to emit light about a 360-degree angle via a light emitting diode (LED) array.

Abstract: A matrix array probe including a transducer array and integrated circuitry coupled to the transducer elements dissipates heat generated by the array and integrated circuitry through the cover of the transducer probe. A pump in the probe connector pumps fluid through a closed loop system including inbound an outbound fluid conduits in the cable. The fluid conduits in the cable are separated by the cable electrical conductors for the probe. The heat transfer in the probe is done by a heat exchanger in the transducer backing block. Additional cooling may be provided by metal to metal contact with a chiller in the ultrasound system.

Abstract: A matrix array probe including a transducer array and integrated circuitry coupled to the transducer elements dissipates heat generated by the array and integrated circuitry through the cover of the transducer probe. A pump in the probe connector pumps fluid through a closed loop system including inbound an outbound fluid conduits in the cable. The fluid conduits in the cable are separated by the cable electrical conductors for the probe. The heat transfer in the probe is done by a heat exchanger in the probe spaceframe or transducer stack backing block and may use a Peltier device. Additional cooling may be provided by metal to metal contact with a chiller in the ultrasound system.

Abstract: The present invention relates to a pre-collapsed capacitive micro-machined transducer cell (10) comprising a substrate (12) comprising a first electrode (16), a membrane (14) comprising a second electrode (18), wherein the cell has an outer region (22) where the membrane (14) is mounted to the substrate (12) and an inner region (20) inside or surrounded by the outer region (22), wherein the membrane (14) is collapsed to the substrate (12) in a first collapsed annular-shaped region (24) located within the inner region (20).

Abstract: The present invention relates to an ultrasound imaging system (10) comprising an ultrasound probe (20) having a transducer array (21) configured to provide an ultrasound receive signal. The system further comprises a B-mode volume processing unit (30) configured to generate a B-mode volume (31) based on the ultrasound receive signal, and a B-mode image processing unit (40) configured to provide a current B-mode image (41) based on the B-mode volume (31). The system further comprises a memory (50) configured to store a previously acquired 3D-vessel map (51). Also, the system comprises a registration unit (60) configured to register the previously acquired 3D-vessel map (51) to the B-mode volume (31) and to select a portion (61) of the 3D-vessel map corresponding to the current B-mode image (41). Further, the system comprises a display configured to display an ultrasound image (71) based on the current B-mode image (41) and the selected portion (61) of the 3D-vessel map (51).

Abstract: The present invention relates to a pre-collapsed capacitive micro-machined transducer cell (10) comprising a substrate (12) comprising a first electrode (16), a membrane (14) comprising a second electrode (18), wherein the cell has an outer region (22) where the membrane (14) is mounted to the substrate (12) and an inner region (20) inside or surrounded by the outer region (22), wherein the membrane (14) is collapsed to the substrate (12) in a first collapsed annular-shaped region (24) located within the inner region (20).

Abstract: The present invention relates to an ultrasound imaging system (10) comprising an ultrasound probe (20) having a transducer array (21) configured to provide an ultrasound receive signal. The system further comprises a B-mode volume processing unit (30) configured to generate a B-mode volume (31) based on the ultrasound receive signal, and a B-mode image processing unit (40) configured to provide a current B-mode image (41) based on the B-mode volume (31). The system further comprises a memory (50) configured to store a previously acquired 3D-vessel map (51). Also, the system comprises a registration unit (60) configured to register the previously acquired 3D-vessel map (51) to the B-mode volume (31) and to select a portion (61) of the 3D-vessel map corresponding to the current B-mode image (41). Further, the system comprises a display configured to display an ultrasound image (71) based on the current B-mode image (41) and the selected portion (61) of the 3D-vessel map (51).

Abstract: A heating device for a rear wall of a tumble dryer is disclosed, wherein the heating device includes an electric heating arrangement which may be formed of heating coils. A bypass airflow which is not directly heated by the heating arrangement flows in addition in the housing so that the heat loss through the housing is reduced.

Abstract: System, method, and computer program product embodiments for receiving customer requests use a request management system. An embodiment operates by establishing a connection with a customer's mobile device, obtaining information about the location of the customer's mobile device, providing to the customer's mobile device a set of data describing goods or services currently offered by one or more business locations, receiving from the customer's mobile device a request for a good or service offered by a particular business location, and adding the request to a queue associated with one or more groups assigned to fulfill the request based on the request type.

Abstract: Disclosed herein are system, method, and computer program product embodiments for receiving staff requests use a request management system. An embodiment operates by receiving a staff request associated with a customer request at the electronic request management system from a mobile device utilized by a first staff member, assigning the staff request to a staging queue defined in the electronic request management system based at least in part on the request type and the location of the customer, selecting the staff request from the staging queue for fulfillment by a second staff member based at least in a part on a geolocation of a mobile device utilized by the second staff member, and providing the staff request from the staging queue to the mobile device utilized by the second staff member for fulfillment by the second staff member.

Abstract: The present invention relates to Shiga toxin effector polypeptides with reduced antigenic and/or immunogenic potential. Immunogenicity can be a limitation for the repeated administration to mammals of proteins and polypeptides derived from Shiga toxins. The Shiga toxin effector polypeptides of the present invention have uses as components of therapeutics, diagnostics, and immunization materials. The cytotoxic proteins of the present invention have uses for selective killing of specific cell types and as therapeutics for the treatment of a variety of diseases, including cancers, immune disorders, and microbial infections. The proteins of the present invention also have uses for detecting specific cell types, collecting diagnostic information, and monitoring the treatment of a variety of diseases, such as, e.g., cancers, immune disorders, and microbial infections.

Abstract: System, method, and computer program product embodiments for receiving customer requests use a request management system. An embodiment operates by establishing a connection with a customer's mobile device, obtaining information about the location of the customer's mobile device, providing to the customer's mobile device a set of data describing goods or services currently offered by one or more business locations, receiving from the customer's mobile device a request for a good or service offered by a particular business location, and adding the request to a queue associated with one or more groups assigned to fulfill the request based on the request type.

Abstract: An Internet protocol (IP) phone is installed in a private branch exchange (PBX) system without a user having to manually correlate the phone's media access control (MAC) address with the phone's extension identifier. In this regard, the PBX is configured to automatically learn the phone's MAC address and correlate such address with an extension identifier entered by the user. Thus, the phone can be installed for use with the PBX system with reduced complexity and burdens for the user.

Abstract: A multi-position biopsy guide system and a method of using such biopsy guide system is proposed. The biopsy guide system comprises a 2D matrix ultrasound transducer (3) and comprises at least one biopsy needle guide (5) adapted for guiding a biopsy needle along a biopsy path (7). Therein, the multi-position biopsy guide system is adapted to controllably guide the biopsy needle along biopsy paths at variable locations with respect to the 2D matrix ultrasound transducer. Preferably, a location of the biopsy needle guide (5) with respect to the matrix ultrasound transducer may be determined and an ultrasound image in an image plane aligned with a biopsy path corresponding to the determined location of the biopsy needle guide may be acquired. Thereby, a biopsy process may be monitored for various locations and orientations of a guided biopsy needle.

Abstract: The present invention relates to a new and distinct variety of apple tree named ‘G.814’. ‘G.814’ is useful in that it can be propagated clonally and used as a rootstock or root system for apple trees as well as for interstems of apple trees. When used as a rootstock, ‘G.814’, is: dwarfing, induces scion precocity, is cold hardy, induces scion precocity, has a high yield efficiency, is tolerant to replant disease, and is resistant to: crown and root rot (Phytophthora cactorum), fire-blight (Erwinia amylovora), and powdery mildew. ‘G.814’ is susceptible to Apple Stem Grooving Virus (ASGV) and wooly apple aphid.