Abstract: Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.

Abstract: A segment core and an axial flux motor. The segment core is formed by covering an SMC core (100, 100?) over an outer peripheral surface of a laminated core (200, 200?). An outer surface of the segment core, which can not be processed easily, is shaped by processing the easily shapeable SMC core (100, 100?). The entire structure of the laminated core (200, 200?) is relatively simple, and thus a mold for processing the laminated core (200, 200?) requires simpler specifications. Moreover, the mold can be used to perform processing easily, to reduce difficulties of processing the segment core. The segment core has better electromagnetic performance than a segment core solely using an SMC material, and has a higher core utilization rate than a segment core solely using a laminated core (200, 200?).

Abstract: Disclosed in the present invention are a cooling system, a stator assembly, and an axial magnetic field motor. The cooling system is used for cooling of a stator core, comprises a housing and an enclosed cavity for containing the stator core, and further comprises: a liquid spraying cavity provided on the housing and used for containing liquid; a liquid inlet in communication with the liquid spraying cavity; a liquid outlet in communication with the enclosed cavity; and a liquid spraying assembly provided on an inner wall, corresponding to the stator core, of the housing.

Abstract: Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. The probes exhibit improved performance compared to industry leading dual-stranded probes; particularly in terms of the rate of hybridization.

Abstract: A segment core and an axial flux motor. The segment core is formed by covering an SMC core (100, 100?) over an outer peripheral surface of a laminated core (200, 200?). An outer surface of the segment core, which can not be processed easily, is shaped by processing the easily shapeable SMC core (100, 100?). The entire structure of the laminated core (200, 200?) is relatively simple, and thus a mold for processing the laminated core (200, 200?) requires simpler specifications. Moreover, the mold can be used to perform processing easily, thereby reducing difficulties of processing the segment core. The segment core has better electromagnetic performance than a segment core solely using an SMC material, and has a higher core utilization rate than a segment core solely using a laminated core (200, 200?).

Abstract: A method for analyzing an image of a tissue section may include obtaining a plurality of image locations, each corresponding to a different one of a plurality of biological structures; obtaining a plurality of locations of a first biomarker in the image; and calculating a distance transform array for at least a portion of the image that includes the plurality of seed locations. The method may include, for each of the plurality of seed locations and based on information from the first distance transform array, detecting whether the first biomarker is expressed at the seed location, and storing, to a data structure associated with the seed location, an indication of whether expression of the first biomarker at the seed location was detected. The method may include detecting, based on the stored indications, co-localization of at least two phenotypes in at least a portion of the tissue section.

Abstract: A display device includes a cover glass, a display panel, a light-absorbing ink layer, and a transparent conductive layer. The cover glass is on a light-emitting side of the display panel, and includes a central light-transmitting area and a peripheral light-shielding area at a periphery of the central light-transmitting area. The light-absorbing ink layer is on a side of the cover glass adjacent to the display panel, and the light-absorbing ink layer is under the peripheral light-shielding area. The transparent conductive layer is between the cover glass and the display panel, and an orthogonal projection of the transparent conductive layer on the cover glass at least partially overlaps with an orthogonal projection of the light-absorbing ink layer on the cover glass.

Abstract: A cooling structure for a disk electric motor, and a disk electric motor are provided. The cooling structure includes: a stator core, a stator housing, multiple first baffles and multiple second baffles. Multiple coils are arranged on the stator core, and there is a gap between adjacent ones of the coils; a stator housing enclosing two end faces of the stator core, where a first cavity is defined by the stator housing and an outer side of the stator core, a second cavity is defined by the stator housing and an inner side of the stator core, where the first cavity and the second cavity are in communication with each other through the gap, and a liquid inlet and a liquid outlet which are in communication with the first cavity are arranged on the stator housing.

Abstract: An integrated piling tool with continuous drilling and circulation pouring includes a power connector, a circulation device, a drill assembly, a bottom clearing and a pouring mechanism. The circulation device includes a circulating drill barrel and a spiral piece, and it achieves cuttings removal continuously; the two ends of the circulating drill barrel are connected with the power connector and the drill assembly, respectively. The drill assembly includes a drill body, a connecting sleeve B, transmission parts, a drill tool holder and drilling teeth, and the drill assembly accomplish rock breaking and rotary excavation. The clearing mechanism includes a linkage and clearing blades to remove cuttings at bottom hole. The pouring mechanism includes pouring channels and control parts to achieve continuous concrete pouring. The invention provides a new integrated piling tool with continuous drilling and circulation pouring, which improves the efficiency of piling, circulation and pouring.

Abstract: Provided is use of an NGF antibody in CIPN pain. In particular, the NGF antibody blocks the interaction of nerve growth factors (NGF) with receptors thereof, and thus can treat and/or prevent chemotherapy-induced peripheral neuropathy (CIPN) pain.

Abstract: The present disclosure provides a method for inducing a lateral branch development of Eucheuma denticulatum, and relates to the technical field of marine organisms. In the present invention, the E. denticulatum is subjected to aeration culture at a light-photon flux of 200 ?mol·m?2·s?1 to 300 ?mol·m?2·s?1. During induction with a high light intensity, new lateral branches continue to grow; after the high-light treatment is completed, the E. denticulatum is placed in its original breeding environment. The dedifferentiation of branch cells into meristems is induced by the high light intensity in E. denticulatum, and then the meristems are developed into lateral branches. An increase of the lateral branches can increase a yield of E. denticulatum, and the high-light treatment can significantly increase a dry matter content of the E. denticulatum to raise an income.

Abstract: A cooling structure for a disc electric motor is provided, including a stator core, a stator housing, a first baffle, a second baffle, a first coil, a second coil, and a partitioner. The first coil and the second coil are arranged on each of stator units. First coils on adjacent stator units are in a close fit with each other, and second coils on the adjacent stator units are in a close fit with each other. The partition plate is interposed between the first coil and the second coil. A third cooling channel, through which a first cavity and a second cavity are communicated, is formed between the adjacent stator units.

Abstract: Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. The probes exhibit improved performance compared to industry leading dual-stranded probes; particularly in terms of the rate of hybridization.

Abstract: The disclosure relates to petroleum drilling, specifically a downhole signal receiving and transmitting device. The downhole signal receiving and transmitting device includes a receiving part, a control device, a mechanical assembly and a transmitting mechanism. The receiving part receives a signal transmitted by a lower end instrument, and the control device process the received signal, controls a motor to drive a rotating sleeve, and the mechanical assembly performs work. The mechanical assembly drives a mandrel to rotate a rotor continuously and regularly. When rotating, the flow area of the rotor and a stator changes to produce continuous pulses. The pressure waveform changes are monitored on the ground, and the measurement data are calculated by decoding.

Abstract: A vehicle-mounted equipment and operation method for rapid detection of danger and hidden danger of a dike is provided, wherein the equipment includes: an operation vehicle; an operation shelter, located behind the cockpit of the operation vehicle and arranged on the chassis of the operation vehicle; a detection system, including a ground penetrating radar detection module, a transient electromagnetic detection module and a seismic wave detection module to perform physical detection of the dike.

Abstract: A thermal recovery construction method includes the steps of determining design parameters of a current thermal recovery construction according to geological data and reservoir characteristics of a current oil deposit area to be stimulated; preparing, according to the design parameters, coal water slurry required for the current thermal recovery construction; injecting the coal water slurry into a target reservoir through an injection well with an injection mode of the design parameters, along with combustion adjuvant with an amount selected based on a total injection amount of the coal water slurry; and inducing spontaneous combustion of the coal water slurry by thermal energy generated by a downhole heating device, and performing control and displacement on the reservoir with the thermal energy and gas generated after the combustion.