Abstract: A dication compound represented by formula (I), stereoisomers having the structure of formula (I) or a mixture of the stereoisomers, a pharmaceutically acceptable salt, a solvate, or a eutectic crystal, and a composition thereof, and use of a composition, are capable of producing neuromuscular junction retardation, formed of same with a pharmaceutically acceptable carrier in the field of preparation of a medicament for muscular flaccidity.

Abstract: The invention relates to an organic polyspiralgrid nanopolymer material and a preparation method thereof, and belongs to the field of nanotechnology and organic electronics. The structure of the organic polyspiralgrid nanopolymer material is composed of grids containing a spiro ring that serves as a repeat unit to form a special nano polymer, and the structure shares the spiro ring structure. A synthetic method thereof relates to a synthon containing the spiro ring, and by means of a Friedel-Crafts reaction, an organic spirogrid and a nano polymer thereof are built. By means of reasonable molecular design and the Friedel-Crafts reaction with the advantages of being mild in reaction condition, high in yield, high in selectivity, simple in posttreatment, green, free of toxicity and the like, the problems that a traditional polymer molecule is complex in synthesis step, toxic in posttreatment, large in pollution and the like are solved.

Abstract: The present invention provides a polyacrylate polymer composite material, characterized by comprising the following components in parts by weight: 100 parts of a polyacrylate polymer, and 15-100 parts of a toughening agent, wherein the toughening agent is selected from a compounding of a two-layer core-shell structure toughening agent and a three-layer core-shell structure toughening agent, and the two-layer core-shell structure toughening agent accounts for 10-45% of the total weight part of the toughening agent. The polyacrylate polymer composite material has the advantages of high transparency and high toughening efficiency, and a prepared film cannot be broken and has no white folding marks after being repeatedly folded in half.

Abstract: This application provides a wireless communication resource allocation method. A network device allocates, to a terminal device, a first resource pool used to carry communication data and a second resource pool including a candidate resource of the first resource pool, the network device measures a quality parameter of at least one physical resource in the first resource pool and the second resource pool, and the network device sends first indication information to the terminal device when a quality parameter of a first physical resource in the first resource pool satisfies a preset condition #1. The first indication information is used to indicate that the first physical resource in the first resource pool is replaced with a second physical resource, and the second physical resource is a physical resource in the second resource pool.

Abstract: Activity data of a set of tasks as a training set is obtained from a list of communication platforms associated with the tasks. For each of the tasks in the training set, a set of activity metrics is compiled according to a set of predetermined activity categories based on the activity data of each task. The activity metrics of all of the tasks in the training set are aggregated based on the activity categories to generate a data matrix. A principal component analysis is performed on the metrics of its covariance matrix to derive an activity dimension vector, where the activity dimension vector represents a distribution pattern of the activity metrics of the tasks. The activity dimension vector can be utilized to determine an activity score of a particular task, where the activity score of a task can be utilized to estimate a probability of completeness of the task.

Abstract: Activity data of a set of tasks as a training set is obtained from a list of communication platforms associated with the tasks. For each of the tasks in the training set, a set of activity metrics is compiled according to a set of predetermined activity categories based on the activity data of each task. The activity metrics of all of the tasks in the training set are aggregated based on the activity categories to generate a data matrix. A principal component analysis is performed on the metrics of its covariance matrix to derive an activity dimension vector, where the activity dimension vector represents a distribution pattern of the activity metrics of the tasks. The activity dimension vector can be utilized to determine an activity score of a particular task, where the activity score of a task can be utilized to estimate a probability of completeness of the task.

Abstract: Activity data of a set of tasks as a training set is obtained from a list of communication platforms associated with the tasks. For each of the tasks in the training set, a set of activity metrics is compiled according to a set of predetermined activity categories based on the activity data of each task. The activity metrics of all of the tasks in the training set are aggregated based on the activity categories to generate a data matrix. A principal component analysis is performed on the metrics of its covariance matrix to derive an activity dimension vector, where the activity dimension vector represents a distribution pattern of the activity metrics of the tasks. The activity dimension vector can be utilized to determine an activity score of a particular task, where the activity score of a task can be utilized to estimate a probability of completeness of the task.

Abstract: A drilling tool is disclosed. The two ends of the drilling tool are respectively connected with an upper drilling tool and a drill bit. The drilling tool includes an axial striking part, a torsional striking part, and an auxiliary part. Under the combined action of a spring and a high-pressure drilling fluid, the hammer of the axial striking part generates an axial striking force to strike the upper housing; and the pendulum of the torsional striking part generates a torsional striking force to strike the lower housing. The reversing switch and the center tube are plugged together to simultaneously reverse torsion and axial striking forces, respectively. The high-pressure drilling fluid pushes the hammer and the pendulum to generate axial and torsional striking forces, respectively, to effectively increase the ROP and reduce the stick-slip phenomenon. The drilling tool is stable and reliable in a complex and changeable downhole environment.

Abstract: A mechanical rotary steering drilling tool for steering a drill string includes a test section, a clutch device, a control mechanism, and an execution part. The test section is used as an upper joint in cooperation with the tool. The clutch device is externally connected with a guide body and internally coupled with a mandrel. A groove on a cylindrical surface of a switch control cylinder is matched with a control screw to determine rotation of a fluid channel switch. A pushing block of the execution part extends out against a wellbore wall to push a drill bit for steering drilling after the fluid channel is opened.

Abstract: A mechanical automatic vertical drilling tool, with ends that are connected with an upper drilling tool and a bit by a detachable thread, is disclosed. The tool comprises a control device, an actuator and an auxiliary part. The control device detects status of wellbore and controls operations of the actuator when the wellbore leans. The actuator pushes a block out against the well wall to generate a radial force, which pushes against the drill bit to prevent deviation and modify the wellbore trajectory. The auxiliary part transmits the indispensable bit pressure and torque for drilling to assist the control device and the actuator to achieve the function. This disclosure can get automatic deviation correction with only mechanical structures. It is simple and reliable, and unlikely to fail in complicated wells without any manual operation.

Abstract: In general, embodiments of the present invention provide systems, methods and computer readable media for a universal relevance service framework for ranking and personalizing items.

Abstract: An integrated piling tool with continuous drilling and circulation pouring includes a power connector, a circulation device, a drill assembly, a bottom clearing and a pouring mechanism. The circulation device includes a circulating drill barrel and a spiral piece, and it achieves cuttings removal continuously; the two ends of the circulating drill barrel are connected with the power connector and the drill assembly, respectively. The drill assembly includes a drill body, a connecting sleeve B, transmission parts, a drill tool holder and drilling teeth, and the drill assembly accomplish rock breaking and rotary excavation. The clearing mechanism includes a linkage and clearing blades to remove cuttings at bottom hole. The pouring mechanism includes pouring channels and control parts to achieve continuous concrete pouring. The invention provides a new integrated piling tool with continuous drilling and circulation pouring, which improves the efficiency of piling, circulation and pouring.

Abstract: A quaternary ammonium salt compound of formula I is fast-acting and has a long-term local anaesthetic effect after a single administration, the sensory nerve block time being longer than the motor nerve block time, has both a long-acting local anaesthetic effect and a selective local anaesthetic effect, and also significantly reduces the side effects of quaternary ammonium salt compounds with the structural features of surfactants and is highly safe; thus, the compound of formula I and the pharmaceutically acceptable salt thereof can be used for the preparation of saft drugs having a long-term local anaesthetic effect and a selective local anaesthetic effect

Abstract: Disclosed in the present invention are a cooling system, a stator assembly, and an axial magnetic field motor. The cooling system is used for cooling of a stator core, comprises a housing and an enclosed cavity for containing the stator core, and further comprises: a liquid spraying cavity provided on the housing and used for containing liquid; a liquid inlet in communication with the liquid spraying cavity; a liquid outlet in communication with the enclosed cavity; and a liquid spraying assembly provided on an inner wall, corresponding to the stator core, of the housing.

Abstract: Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. The probes exhibit improved performance compared to industry leading dual-stranded probes; particularly in terms of the rate of hybridization and the ability to achieve specific hybridization without blocking DNA.

Abstract: This application discloses a method for controlling an optical sensing circuit, an optical sensing circuit, and an imaging device. The optical sensing circuit includes an optical sensor and a voltage dividing circuit connected in series, an input voltage (a voltage of the voltage dividing circuit) and an output voltage are obtained, a resistance value of the optical sensor is calculated according to the input voltage, a light intensity value is obtained according to the resistance value of the optical sensor, and then, different loads are controlled based on a level of the output voltage for light intensity in different ranges to perform corresponding operations. This application has high flexibility and strong adaptability, and can effectively broaden an application scope of a photosensitive device.

Abstract: The present disclosure is directed to epitope-tagged antibodies, as well as methods of employing the epitope-tagged antibodies for detecting one or more targets in a biological sample, e.g. a tissue sample.

Abstract: Methods and compositions for accurate identification of Parkinson's disease are disclosed. More particularly, the disclosure is directed to the determination of Parkinson's disease in ante-mortem tissue samples.

Abstract: In general, embodiments of the present invention provide systems, methods and computer readable media for a universal relevance service framework for ranking and personalizing items.

Abstract: An N-substituted imidazole carboxylate compound is of formula (I). In formula (I), C* is an R-type chiral carbon atom, R1 and R2 are independently selected from H, methyl, ethyl, cyclopropyl, cyclobutyl or isopropyl, or R1 and R2 form a C2˜5 alkylenyl group; R3 is a substituted or unsubstituted C1-18 saturated or unsaturated aliphatic hydrocarbon or aromatic hydrocarbon, in which the aliphatic hydrocarbon comprises a straight chain, branched chain or cyclic aliphatic hydrocarbyl. The compound or pharmaceutically acceptable salts thereof can be used to prepare central inhibitory drugs that exert sedative, hypnotic and/or anesthetic effects on humans or animals, and can produce rapid and reversible anesthetic effects, and can be rapidly metabolized into an inactive etomidate acid, and after drug withdrawal, the wake-up quality is good; and the body's corticosteroid function can be rapidly recovered after a single administration or continuous administration.