Abstract: A method, system and computer readable medium for an intelligent search display into which an automated computerized image analysis has been incorporated. Upon viewing an unknown mammographic case, the display shows both the computer classification output as well as images of lesions with known diagnoses (e.g., malignant vs. benign) and similar computer-extracted features. The similarity index used in the search can be chosen by the radiologist to be based on a single feature, multiple features, or on the computer estimate of the likelihood of malignancy. Specifically the system includes the calculation of features of images in a known database, calculation of features of an unknown case, calculation of a similarity index, display of the known cases along the probability distribution curves at which the unknown case exists.

Abstract: Bioadhesive, closed-cell foam film, sustained release, delivery devices for administering an active agent or combination of active agents to a subject are provided. Methods for making such delivery devices and methods for using such delivery devices offering the controlled and sustained release of an active agent or combination of active agents to a subject, preferably a near zero-order release, are also provided.

Abstract: A wheel supporter with a brake includes a rotary shaft, a base, a pedal, a brake plate and a return spring. The base has a covering member, a shaft support member, and an eccentric support member. The eccentric support member has an upper stage provided with a sidewise round post, and the brake plate has a front projection, two wings provided in a rear portion, and an upper recess formed to mount on the round post. If the pedal is stepped down, the brake plate is pressed down to force the wings contact the wheel to produce frictional resistance against the wheel, and at the same time the front projection of the brake plate fits in one of the gaps formed by every two teeth of a disc gear fixed with a lower end of the rotary shaft to stop the rotary shaft immovable. The brake plate is easily combined with the wheel supporter, and applicable to various types of wheels.

Abstract: A caster includes a wheel, and a connecting shaft mechanism for holding the wheel in position; the shaft mechanism includes a sleeve consisting of two half parts, and a supporting shank member, which is held in the sleeve at an upper end, and with which the wheel is connected; the supporting shank member is formed with two flat portions, which face outwards in opposite directions; the sleeve half parts are connected together by means of bolts with inward sides thereof facing each other; each of the sleeve half parts has a flat portion on the inward side thereof; the flat portions of the sleeve half parts touch respective ones of the flat portions of the supporting shank member for preventing angular displacement of the supporting shank member relative to the sleeve.

Abstract: The products and methods of the present invention provide a means for increasing the solubility and bioavailability of active agents. More particularly the invention provides compositions containing active agents as water-soluble complexes with glycyrrhizin, and methods of preparing such complexes. The invention further provides methods for the preparation of highly water soluble complex dosage forms.

Abstract: Rapidly dissolving, oral film preparations for rapid release of an active agent in the oral cavity, in particular, rapidly dissolving oral films comprising a nicotine active which achieve good transbuccal absorption and provide nicotine craving relief to an individual are disclosed herein.

Abstract: A caster includes a connecting part, a rotary support, a fork, a wheel, upper and lower springs, and a connecting stick; the connecting part is secured to a bottom side of a piece of furniture; the rotary support is arranged under and connected to the connecting part; the fork is arranged under and pivoted to the rotary support while the wheel is connected to the fork; the lower spring is positioned under an upper portion of the fork while the upper spring is positioned between the upper portion of the fork and the rotary support; the connecting stick is passed through the lower spring, the upper portion of the fork, and the upper spring in sequence, and securely connected to the rotary support at an upper end; thus, the upper and the lower springs will reduce upward and downward jolts respectively while the furniture is being moved along a rugged land.

Abstract: A method, system, and computer software product for correlating medical images, comprising: obtaining first image data representative of a first medical image including a first abnormality; obtaining second image data representative of a second medical image including a second abnormality; determining at least one feature value for each of the first and second abnormalities using the first and second image data; calculating, based on the determined feature values, a likelihood value indicative of a likelihood that the first and second abnormalities are a same abnormality; and outputting the determined likelihood value.

Abstract: A caster includes a wheel, and a connecting shaft mechanism for holding the wheel in position; the shaft mechanism includes a sleeve consisting of two half parts, and a supporting shank member, which is held in the sleeve at an upper end, and with which the wheel is connected; the supporting shank member is formed with two flat portions, which face outwards in opposite directions; the sleeve half parts are connected together by means of bolts with inward sides thereof facing each other; each of the sleeve half parts has a flat portion on the inward side thereof; the flat portions of the sleeve half parts touch respective ones of the flat portions of the supporting shank member for preventing angular displacement of the supporting shank member relative to the sleeve.

Abstract: A method for computer-assisted interpretation of medical images that factor in characteristics of an individual performing the interpretation. The method automatically determines and/or incorporates prevalence-based computer analysis based on an estimated likelihood of a pathological state, e.g., a malignancy. A system implementing the method includes the calculation of features or other characteristics of images in a known database, calculation of features of an unknown case, calculation of the probability (or likelihood) of disease state, calculation of the modified computer output that includes the internal prevalence (or internal decision-making process) of the user (or group of users), and output of the result.

Abstract: An interactive counter service system for banks and similar finance organizations mainly includes a touch-screen module, a counter-terminal module, and network communicating equipment. The touch-screen module is mounted at counters of the banks to serve as an interface via which a customer may select one or more desired transactions provided by the bank and input required data via a magnetic strip reader or a card reader of the touch-screen module. The counter-terminal module enables a counter clerk to synchronously receive and process the data input by the customer and provide on-line business consultation to help the customer to complete the selected transaction. The interactive counter service system effectively improves the interactive relation between the customer and the bank and thereby upgrades the service quality of the bank.

Abstract: A method, system and computer readable medium for an intelligent search display into which an automated computerized image analysis has been incorporated. Upon viewing an unknown mammographic case, the display shows both the computer classification output as well as images of lesions with known diagnoses (e.g., malignant vs. benign) and similar computer-extracted features. The similarity index used in the search can be chosen by the radiologist to be based on a single feature, multiple features, or on the computer estimate of the likelihood of malignancy. Specifically the system includes the calculation of features of images in a known database, calculation of features of an unknown case, calculation of a similarity index, display of the known cases along the probability distribution curves at which the unknown case exists.

Abstract: A method, system and computer readable medium for an intelligent search display into which an automated computerized image analysis has been incorporated. Upon viewing an unknown mammographic case, the display shows both the computer classification output as well as images of lesions with known diagnoses (e.g., malignant vs. benign) and similar computer-extracted features. The similarity index used in the search can be chosen by the radiologist to be based on a single feature, multiple features, or on the computer estimate of the likelihood of malignancy. Specifically the system includes the calculation of features of images in a known database, calculation of features of an unknown case, calculation of a similarity index, display of the known cases along the probability distribution curves at which the unknown case exists.

Abstract: Bioadhesive, closed-cell foam film, sustained release, delivery devices for administering an active agent or combination of active agents to a subject are provided. Methods for making such delivery devices and to methods for using such delivery devices offering the controlled and sustained release of an active agent or combination of active agents to a subject, preferably a near zero-order release, are also provided.

Abstract: Bioadhesive, closed-cell foam film, sustained release, delivery devices for administering an active agent or combination of active agents to a subject are provided. Methods for making such delivery devices and to methods for using such delivery devices offering the controlled and sustained release of an active agent or combination of active agents to a subject, preferably a near zero-order release, are also provided.

Abstract: Oral drug complex microparticles containing: a pharmaceutical active having a nitrogen moiety and an anionic methacrylic acid copolymer; wherein the oral drug complex micropaticles resist dissolution or dissociation upon exposure to saliva, but which rapidly dissociate in gastric acid and which rapidly dissolve in intestinal fluid. Oral drug delivery devices containing said oral drug complex microparticles are provided. Processes for producing said oral drug complex microparticles and methods for treating patients including administering said oral drug delivery devices thereto are also provided.

Abstract: The present invention is directed to compositions comprising an angiogenesis inhibitor coupled to a therapeutic or diagnostic agent. In a specific embodiment, the composition is a fusion gene or fusion gene product encoding the angiogenesis inhibitor coupled to a therapeutic or diagnostic agent. In a particular embodiment, the composition is used for methods to treat angiogenesis-related diseases, such as cancer.

Abstract: A method, system, and computer program product for identifying at least one three-dimensionally extended lesion within a volumetric region encompassing an inner surface, an outer surface, and intervening tissue of a target organ. The method includes: (1) generating a set of voxels representing a total scanned volume from a set of cross-sectional images of the target organ; (2) performing segmentation to extract a set of voxels representing the volumetric region from the set of voxels representing the total scanned volume; (3) detecting a set of candidate lesions based on geometric feature values of each voxel in the set of voxels representing the volumetric region; and (4) selecting the at least one three-dimensionally extended lesion from the set of candidate lesions based on at least one of volumetric, morphologic, and texture feature values of each lesion in the set of candidate lesions.

Abstract: Drug delivery devices for administering an active agent or a combination of active agents to a subject are provided.

Abstract: Quick dissolving oral mucosal drug delivery devices having a mucosal surface-coat-forming inner layer disposed between two moisture barrier coating layers for administering an active agent or combination of active agents to a subject are provided. Methods for making such quick dissolving oral mucosal drug delivery devices and to methods for using such quick dissolving oral mucosal drug delivery devices offering the measured and controlled release of an active agent or combination of active agents to a subject are also provided.