Abstract: Provided is a linker-containing antibody drug conjugate. Also involved are a pharmaceutical composition comprising the antibody conjugate, a use of a linker, and a use of the antibody conjugate in the preparation for a drug for preventing and/or treating diseases.

Abstract: A method of self-testing a transceiver integrated circuit substrate includes: providing a test signal to a transmission line that is communicatively coupled, or selectively communicatively coupled, to an input of a power amplifier of a first transceiver subcircuit of the transceiver integrated circuit substrate; providing the test signal from the transmission line to an LNA of an LNA of a second transceiver subcircuit of the transceiver integrated circuit substrate; and measuring the test signal before amplification by the LNA, or after amplification by the LNA, or both.

Abstract: An electronic device includes an audio processing unit, a first-type array element, and a second-type array element. The audio processing unit is configured to: receive an initial audio signal, and determine a first-type audio signal and a second-type audio signal based on the initial audio signal, where the first-type audio signal includes M first audio signals, and the second-type audio signal includes N second audio signals. The audio processing unit is further configured to send the first-type audio signal to the first-type array element, and send the second-type audio signal to the second-type array element. The first-type array element is configured to output M first sound wave signals based on the corresponding first audio signals. The second-type array element is configured to output N second sound wave signals based on the corresponding second audio signals.

Abstract: A composite oxide and a silicon capture agent, preparation methods therefor and the use thereof in hydrocarbon hydrogenation, and a method for treating a silicon-containing oil product are provided. The composite oxide has aluminum oxide and pseudo-boehmite. The pseudo-boehmite is loaded on the outer surface of the aluminum oxide, and the surface hydroxyl content of the composite oxide is 1,000-2,500 ?mol/g. The silicon capture agent has aluminum oxide, pseudo-boehmite and an active component. The active component contains a group-VIB metal sulfide and a group-VIII metal sulfide; and the surface hydroxyl content of the silicon capture agent is 1,000-2,000 ?mol/g. The composite oxide and the silicon capture agent provided have an improved surface hydroxyl content and an improved silicon capacity.

Abstract: The present application discloses a filament feeding apparatus for a 3D printer and a 3D printer. The filament feeding apparatus for a 3D printer comprises: a filament housing; a fixed tube and a sliding block, wherein one end of the fixed tube is connected to one end of a feed tube, the other end of the feed tube is connected to a feed assembly, a buffer chamber is formed within the sliding block, one end of the sliding block distal to the feed tube is further connected to one end of an extrusion tube interconnected to the buffer chamber, and the other end of the extrusion tube is coupled to an extrusion assembly; and a first elastic member and a second elastic member.

Abstract: An apparatus for wireless communications includes a power amplifier, a low-noise amplifier, a power detector, and a transformer. The transformer includes a first inductor coupled to an output of the power amplifier, and a second inductor coupled to an antenna, wherein the second inductor is magnetically coupled with the first inductor. The transformer also includes a third inductor coupled to an input of the low-noise amplifier, wherein the third inductor is magnetically coupled with the second inductor. The transformer also includes a coupling inductor coupled to an input of the power detector, wherein the coupling inductor is magnetically coupled with at least one of the first inductor and the second inductor.

Abstract: The present disclosure relates to a coring assembly for extraterrestrial drilling and a preparation method of the coring assembly for extraterrestrial drilling. The coring assembly for extraterrestrial drilling includes: a limit locking mechanism, a flexible coring rotary body, a variable-diameter cone, an equal-tension bundled rope, and an end cap. One end of the flexible coring rotary body is connected to the limit locking mechanism, and the other end of the flexible coring rotary body is connected to one end of the variable-diameter cone. The flexible coring rotary body and the variable-diameter cone form a flexible coring structure. A storage structure is connected within the variable-diameter cone; and the other end of the variable-diameter cone is connected to the end cap via the equal-tension bundled rope.

Abstract: An adsorbent is in a liquid-phase hydrogenation catalyst composition. A catalyst bed containing the liquid-phase hydrogenation catalyst composition may be applicable in adsorption technology or oil liquid-phase hydrogenation technology. The adsorbent contains a porous material and a hydrogenation active metal supported on the porous material. The adsorbent has an average pore diameter of 2-15 nm, a specific surface area of 200-500 m2/g, and the hydrogenation active metal is present in an amount, calculated as metal oxide, of 2.5 wt % or less, based on the total weight of the adsorbent. The adsorbent has a high hydrogen sulfide adsorption efficiency for a long period of time, and can effectively prolong the protection period for the hydrodesulfurization catalyst.

Abstract: A sub-surface safety valve (SSSV) for use in a low temperature downhole environment. The low temperature environment can be created by injection of fluid such as carbon dioxide. The low temperature downhole environment may be detrimental to the SSSV by damaging elastomer seals. The disclosed SSSV utilizes non-elastomeric seals and metal-to-metal seals between components. The SSSV utilizes metal-to-metal threads between body joints eliminating the need for an elastomers in the threads between body joints. Creating a SSSV with an elastomer seal reduces fatigue and damage in a low temperature environment.

Abstract: A display module and a display apparatus are provided in an embodiment of the present disclosure. The auxiliary member included in the display module is a cushion layer; the cushion layer is arranged at a bottom of the lapping hole, the first surface of the planarization layer is a surface of the planarization layer away from the cushion layer, and a first surface of the first source-drain metal layer is a surface of the first source-drain metal layer away from the cushion layer.

Abstract: The present disclosure relates to a method of preparing an aluminum-containing alloy powder and an application thereof. The preparation method includes: by using the characteristic that a solidification structure of an initial alloy includes a matrix phase and a dispersed particle phase, the matrix phase is removed by reaction with an acid solution, so as to separate out the dispersed particle phase and obtain an aluminum-containing alloy powder. The preparation method is simple in process and can prepare different morphologies of aluminum-containing alloy powders of nano-level, sub-micron-level, micron-level and millimeter-level, which can be applied to the fields such as photo-electronic devices, wave absorbing materials, catalysts, 3D metal printing, metal injection molding and corrosion-resistant coating.

Abstract: A method for intelligently extracting a sand body configuration boundary based on seismic data is provided, including: collecting seismic data from a study region, obtaining seismic attribute prediction data of a sand body thickness in the study region; determining morphologically reconstructed attribute data by performing morphological reconstruction top-hat transformation on the seismic attribute prediction data; determining a discontinuous boundary of a sand body in the study region by performing a morphological gradient calculation on the morphologically reconstructed attribute data according to a designed morphological gradient operator; calculating a complexity parameter for the discontinuous boundary, quantitatively characterizing an irregularity degree of the discontinuous boundary, and determining a regional division count for each closed contour; and constructing an extension table by performing feature point filtering based on a curvature of an internal regional boundary, and identifying a sand bod

Abstract: Disclosed is a heterocyclic compound as represented by formula (I), a tautomer thereof, or a pharmaceutically acceptable salt thereof. The compound has better inhibitory activity on TRPC5, has good metabolic stability in liver micro-particles, and has good clinical pharmacokinetic properties.

Abstract: An emulsion, an emulsion gel electrolyte, an aerogel, as well as a preparation method and a use; wherein the emulsion is an oil-in-water emulsion. An oil phase is a solution of decane dispersed with an upconversion nanomaterial and a water phase contains a polymerizable ionic liquid. The gel electrolytes and aerogel electrode materials prepared based on this emulsion have greatly improved the electrochemical performance of supercapacitors.

Abstract: The present application provides a mutant protein of activation-induced cytidine deaminase, wherein the mutant protein has the following mutations when compared to hsAID: T82I, K10E, K34E, E156G, 181*, S38C, H130R, V152A, R174G, and T110A. The present application also provides a high-efficiency base editor, including the mutant protein of activation-induced cytidine deaminase of the present application and a DNA-specific binding protein, which are linked sequentially via a linking sequence. The present application also provides a targeted single-base editing system, including a targeted single-base editing protein and a target hyper mutation fragment. Compared with the existing single-base editing system based on activation-induced cytidine deaminase (AID), the system for inducing the mutant protein of the present application has a smaller molecular weight and higher mutation efficiency.

Abstract: A visual tracking system helps to detect or locate an active object (such as an active sound source) in a live video or recorded video, and provides a way to help a user who views the live video or recorded video to focus on the active object, without easily being disturbed or distracted by other objects that are present with the active object. The visual tracking system may further track the active object, or detect a new active object when the live video or recorded video is played.

Abstract: A compound containing a benzene ring as shown in formula I, a pharmaceutically acceptable salt thereof, a stereoisomer thereof, a tautomer thereof, an isotopic compound thereof, a crystal form thereof, a nitrogen oxide thereof, and a solvate thereof or a solvate of the pharmaceutically acceptable salt thereof are provided. The compound has high P2X4 antagonistic activity, good selectivity, low toxicity and good metabolic stability.

Abstract: A process for converting amino sugar to fructose and ammonia using one enzyme. Also provided are compositions and enzymes for converting amino sugar to fructose and ammonia.

Abstract: The first source-drain metal layer included in the display module is located in a lapping area of the planarization layer, and the anode metal layer is stacked on the planarization layer. The first source-drain metal layer and the anode metal layer are electrically connected to each other through a lapping hole disposed in the lapping area. A first surface of the planarization layer includes a first area and a second area, wherein the first area is an area where the first surface of the planarization layer is parallel to a plane where the anode metal layer is located, the second area is an area where a first surface of the planarization layer intersects with the plane where the anode metal layer is located, and the first surface of the planarization layer is a surface opposite to the anode metal layer.

Abstract: A sub-surface safety valve (SSSV) for use in a low temperature downhole environment. The low temperature environment can be created by injection of fluid such as carbon dioxide. The low temperature downhole environment may be detrimental to the SSSV by damaging elastomer seals. The disclosed SSSV utilizes non-elastomeric seals and metal-to-metal seals between components. The SSSV utilizes metal-to-metal thread between body joints eliminating the need for an elastomers in the thread between body joints. Creating a SSSV with an elastomer seal reduces fatigue and damage in a low temperature environment.