Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Abstract: A crystalline precursor compound for manufacturing a lithium transition metal based oxide powder usable as an active positive electrode material in lithium-ion batteries, the precursor having a general formula M(O)x(OH)2-x-y(CO3)y, with 0<x?1, 0<y<0.03 and M=NiaMnbCocAd. A being a dopant, with 0.30?a<0.90, 0.10?b<0.40, 0.10?c<0.40, d<0.05 and a+b+c+d=1, the precursor having a Na content less than 200 ppm, a S content less than 250 ppm, the precursor having a specific surface area with a BET value expressed in m2/g and a tap density TD expressed in g/cm3, with a ratio BET/TD>30.104 cm5/g2.

Abstract: Systems and methods are described for a slave PHY device retransmitting a waking up command to a master PHY device in a low-power mode. After transmitting a wake-up command to the master PHY device, the slave PHY device starts a timer. If the timer reaches a threshold time, the slave device retransmits the wake-up command.

Abstract: An underframe boundary beam connecting structure suitable for a railway vehicle with a drum-shaped vehicle body is provided. An underframe boundary beam is a through long roll bending piece, a section of the through long roll bending piece is of a channel structure, and has a side face, an upper wing face, and a lower wing face. The side face has an inclination angle consistent with a side wall plate, an upper end of an outer side of the side face is provided with a concave platen, and the side wall plate is lapped on the concave platen and fixed by a butt welding; an inner end of the lower wing face is provided with a downwards vertical flanging, a vertical plate is welded and fixed between the upper wing face and the lower wing face.

Abstract: A receiver includes an interface and a processor. The interface is configured to receive a signal including symbols carrying bit values in respective symbol intervals, and to convert the received signal into a serial sequence of digital samples, the received signal being modulated using a Differential Manchester Encoding (DME) scheme that (i) represents a first bit value by a first symbol type having a level transition in the corresponding symbol interval and (ii) represents a second bit value by a second symbol type having a constant level in the corresponding symbol interval. The processor is configured to derive an error signal from the digital samples, and to produce a quality measure of the received signal based on the derived error signal.

Abstract: Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically, quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described.

Abstract: A method for waking up, from a low-power mode, a first communications node coupled to a second node via a first communication link, includes determining, while the first node is awake, a first transmission rate for transmitting data over the first link, storing the first rate at the second node, and selectively transmitting, from the second node to the first node, a first wake-up command at a symbol rate corresponding to the first rate. Where a third node is coupled to the second node via a second link, the method may further include determining, at the second node, while the third node is awake, a second transmission rate for transmitting data over the second link, storing the second rate at the second node, and selectively transmitting, from the second node to the third node, a second wake-up command at a symbol rate corresponding to the second rate.

Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Abstract: A first communication device generates an Operation, Administration, and Maintenance (OAM) frame that includes i) OAM message content and ii) an OAM frame header outside of the OAM message content, wherein generating the OAM frame comprises generating the OAM frame header to include information that signals one of i) a low power sleep (LPS) request, and ii) a wake-up request (WUR). The first communication device transmits the OAM frame to a second communication device via a communication medium to signal to the second communication device the one of i) the LPS request, and ii) the WUR.

Abstract: A robot system for oral cavity and tooth treatment. The system includes a console, a seat device, a robot and a navigation device. The console includes a display device, an operating device and an emergency stop device. The seat device includes a body support portion, an orientation adjustment portion and a head fixing portion. The robot comprises a main controller, a robotic arm, a manipulator. The navigation device performs navigation inside a tooth in a root canal treatment operation according to pre-stored tooth information. The treatment instrument in the manipulator can be replaceable. The seat device can be adjusted such that a patient can face any direction between forward and downward, or lie prostrate.

Abstract: An electrical connector includes multiple electrical modules sequentially stacked along a vertical direction. Each electrical module includes an insulating block being arc-shaped, a row of conductors fixed to the insulating block, and a first shielding member. The row of conductors includes multiple first grounding conductors and multiple pairs of first signal conductors arranged on the insulating block along a left-right direction. The two first signal conductors in a same pair of first signal conductors have a same length. The first shielding member has a first main body portion overlapping with a projection of one pair of first signal conductors in the vertical direction. The first shielding member and each conductor bend and extend downward from a top thereof and backward from a front thereof to be arc-shaped. The first contact portions of the row of conductors located on the same electrical module are located on a same horizontal plane.

Abstract: A time flight depth camera and a distance measuring method are provided. The time flight depth camera comprises: a light source for emitting a pulse beam to an object; an image sensor comprising at least one pixel, wherein each of the at least one pixel comprises taps, and each tap is used for acquiring a charge signal based on a reflected pulse beam due to the pulse beam reflected from the object to be measured or a charge signal of background light; and a processing circuit configured to control the light source to emit pulse beams in adjacent frame periods, receive charge signals of the taps in the adjacent frame periods, determine whether the charge signals comprise the charge signal of the reflected pulse beam, and calculate a time of flight of the pulse beam and/or a distance to the object according to a result of the determining.

Abstract: Disclosed herein are methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating relationship recommendations. One of the methods includes: determining, by a computing device, parameter entities that comprise event entities associated with node entities; constructing, by the computing device, a knowledge graph based on relationships between the parameter entities and predetermined operator entities; extracting, by the computing device, a newly added relationship from the knowledge graph based on an inference rule; and providing, by the computing device, a relationship recommendation corresponding to the newly added relationship.

Abstract: Embodiments described herein provide a method for waking a first node in a low power mode. A network comprises at least the first node and a second node in an awake mode where the first and second nodes have respective transceivers coupled via substantially fixed communication pathways. The transceiver of the second node obtains a training signal designed to be transmitted at a pre-defined symbol rate and transmits the training signal at a symbol rate lower than the pre-defined symbol rate to the physical layer of the first node for a predetermined duration of time. The second node, in response to receiving the training signal transitions from the low power mode to an awake state.

Abstract: The present disclosure relates to a cleaning device and a chemiluminescence detector. A cleaning device is provided with a cup inlet station and a cup outlet station, wherein the cleaning device comprises a pedestal, a plurality of magnetic adsorption components, a turntable arranged on the pedestal, and a primary cleaning mechanism arranged on the pedestal, wherein each of the plurality of magnetic adsorption components comprises a plurality of magnets; magnetic adsorption heights of a plurality of magnets of the first magnetic adsorption component are equal and are recorded as A; magnetic adsorption heights of a plurality of magnets of the middle magnetic adsorption component are equal and are recorded as B, and B>A.

Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Abstract: A precursor compound for manufacturing a lithium transition metal based oxide powder usable as an active positive electrode material in lithium-ion batteries, the precursor being either one of a metal-bearing M?-hydroxide, -oxyhydroxide or -carbonate, with M?=Ni1-x-y-zMnxCOyAz with x>0, y>0, 0.70?1-x-y-z?0.95 and 0?z<0.1, the precursor comprising having a core comprising a metal-bearing compound M?c and a shell comprising a metal-bearing compound M?s, wherein M?c=Ni1-xc-yc-zcMnxcCOycAzc with 0<xc?0.2, 0<yc?0.2, 0?zc<0.1 and 0.75?1-x-y-z?0.95, and M?s=Ni1-xs-ys-zsMnxsCOysAzs with 0<xs?0.25, 0.75<ys?0.95, 0?zs<0.1 and 0?1-xs-ys-zs?0.10.

Abstract: A method for managing a region tag comprises: acquiring region identifier information of a geographic region; acquiring an attribute evaluation tag of the geographic region by a user in the geographic region and a time identifier of the attribute evaluation tag; integrating the region identifier information, the attribute evaluation tag, and the time identifier thereof into a region tag of the geographic region; clustering region tags to generate a region time period tag of the geographic region for a time period based on that each region tag comprises the region identifier information of the geographic region and a time identifier within the time period, wherein the region time period tag of the geographic region for the time period corresponds to a function attribute of the geographic region for the time period; and outputting region time period tags of the geographic region for time periods, respectively.

Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.