Abstract: A TCP bypass interdiction method and device are provided. The method comprises: a DPI device between a client terminal and a service terminal acquiring a MSS negotiation value on the basis of a TCP handshake packet; when a suspicious packet is monitored, the DIP device constructing an RST packet according to the suspicious packet and the MSS negotiation value. The RST packet comprises a source direction RST packet and target direction RST packets. The receiving terminal of the source direction RST packet is the same with the transmitting terminal of the suspicious packet. The receiving terminals of the target direction RST packets are the same with the receiving terminal of the suspicious packet. SEQ values of the target direction RST packets are sequentially increased by at least one MSS negotiation value. The method comprises the DPI device transmitting the RST packet to the client terminal and the service terminal respectively.

Abstract: The disclosure provides a chemiluminescence detector. The chemiluminescence detector includes a reagent storage device, configured to store a reagent; a reaction device, configured to support a plurality of support reaction containers and perform a sample adding operation, a reagent adding operation and an incubating operation, the reaction device including a reaction outer disc mechanism configured to support the reaction containers and perform the reagent adding operation and an uniform mixing operation and a reaction inner disc mechanism configured to support the reaction containers and perform the incubating operation; a reagent storage device, a separate injection device, a cleaning device and a measuring device are arranged around an outer periphery side of the reaction outer disc mechanism.

Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: An ultrasonic system has an ultrasonic stack excited by a power supply. The ultrasonic stack has a plurality of components, including an ultrasonic converter, a booster and an ultrasonic horn. A method of controlling the ultrasonic system with the power supply includes upon replacing any of the components of the ultrasonic stack with a replacement component, inputting an amplitude parameter of the replacement component into the power supply, determining with the power supply an amplitude of an AC excitation signal at which to excite the ultrasonic converter based on amplitude parameters of the components including the amplitude parameter of each replacement component. The power supply then sets the amplitude of the AC excitation signal at this determined amplitude.

Abstract: Disclosed a chemiluminescence enhancer and a chemiluminescence immunodetection kit. The chemiluminescence enhancer is specifically a betaine and can be used for enhancing the luminance of a luminescent acridine substance. The chemiluminescence immunodetection kit comprising the chemiluminescence enhancer and a luminescent acridine substance features greatly enhanced luminescence signals and high detection sensibility, and can be widely applied to fields such as clinical diagnoses, scientific research, and sanitation analysis.

Abstract: The present disclosure provides a consumable box automatic transmission device. The consumable box automatic transmission device includes a consumable box storage mechanism, configured to load and store consumable boxes, and a consumable box lifting mechanism, located above the consumable box storage mechanism; the consumable box lifting mechanism is able to lift the consumable boxes; the consumable box storage mechanism and the consumable box lifting mechanism is able to respectively store and transmit the consumable boxes; the consumable box storage mechanism is able to transmit the consumable boxes to the bottom of the consumable box lifting mechanism; and the consumable box lifting mechanism receives the consumable boxes at a bottom and lifts the consumable boxes to a top layer of the consumable box lifting mechanism. In this way, parallel consumable box transmission can be achieved, and continuous consumable box conveyance is achieved, thereby reducing manual care or frequent manual operation.

Abstract: The present disclosure relates to a sample rack loading system and loading method, and a chemiluminescence detector. The loading system includes: a sample rack storage device, provided with multiple sample holders for storing sample racks; a sample rack transmission device, comprising a rail component and a sample rack block piece mechanism; and a sample rack transfer device, transfers the sample racks between the sample rack storage device and the sample rack transmission device; the sample rack block piece mechanism is configured to block or unblock transmission passages of the rail component; and a guide block is arranged on the sample rack transfer device. When transfer rails of the sample rack transfer device are in abutment with the transmission passages, the guide block drives the sample rack block piece mechanism to unblock the transmission passages.

Abstract: The present disclosure relates to a measuring chamber, a working method of the measuring chamber, a chemiluminescence measurement method of the measuring chamber and a chemiluminescence detector. The measuring chamber includes a dark chamber, a first substrate nozzle, a photomultiplier detection component, a waste liquor adsorption needle component, a reaction cup turntable and a plurality of reaction cup processing stations; the reaction cup turntable is provided in the measuring chamber rotationally; and the plurality of reaction cup processing stations are sealed in a mutually light-isolated manner. When the instrument works, reaction cups in the reaction cup turntable are moved in the dark chamber; and after the reaction cups are moved to corresponding processing stations for processing the reaction cups, the plurality of different processing stations for processing, the reaction cups may simultaneously process the reaction cups moved to the corresponding reaction cup processing stations.

Abstract: A motion sensor has an infrared detector with a first set of detector elements coupled to a first channel and a second set of detector elements coupled to a second channel. A first optical subsystem directs infrared radiation from a first number of monitored volumes to the infrared detector and a second optical subsystem directs infrared radiation from a second number of monitored volumes to the infrared detector. Intrusion detection circuitry is coupled to both channels of the infrared detector and selects a set of peaks in the first channel and the second channel. It then calculates an alternation score based on a number of alternating peaks in the set of peaks, and indicates an intrusion detection based, at least in part, on the alternation score. The circuitry also determines a peak-to-peak period for the first channel and calculates a slope-synchrony measurement to modify the alternation score.

Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Abstract: A gimbal for controlling an optical device includes a rocker and a controlling assembly. The rocker is configured to receive an action instruction and generate a control instruction based at least in part on a duration of the action instruction. The controlling assembly is configured to (1) receive the control instruction from the rocker, and (2) generate, based on the control instruction, a performing instruction for controlling the optical device.

Abstract: Benzenesulfonamide derivatives of quinoxaline that are kinase inhibitors, pharmaceutical compositions and methods of using these derivatives, e.g., for treatment of cancer are described.

Abstract: A reaction cuvette moving device and a fully automatic chemiluminescence immunoassay apparatus. The reaction cuvette moving device includes a transmission mechanism and a push mechanism, wherein the transmission mechanism comprises a baseplate and a first horizontal transmission mechanism provided on the baseplate. The push mechanism includes a support assembly, a second horizontal transmission mechanism provided on the support assembly, and a push rod connected to the second horizontal transmission mechanism.

Abstract: A particulate precursor compound for manufacturing a lithium transition metal (M)-oxide powder for use as an active positive electrode material in lithium-ion batteries, wherein (M) is NixMnyCozAv, A being a dopant, wherein 0.33?x?0.60, 0.20?y?0.33, and 0.20?z?0.33, v?0.05, and x+y+z+v=1, the precursor comprising Ni, Mn and Co in a molar ratio x:y:z and having a specific surface area BET in m2/g and a sulfur content S expressed in wt %, wherein formula (I).

Abstract: A gimbal for controlling an optical device includes a rocker for receiving an action instruction and generating a control instruction. The rocker comprises a keypad for switching between two or more operating modes of the gimbal. The operating modes of the gimbal comprise (1) a follow mode in which a shooting direction of the optical device follows a moving direction of the gimbal and (2) a locked mode in which the shooting direction of the optical device is locked in a specified direction regardless of movement of the gimbal. The gimbal further includes a controlling assembly configured to (1) receive the control instruction from the rocker, and (2) generate, based on the control instruction, a performing instruction for controlling the optical device.

Abstract: Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described.

Abstract: Chemical entities that are quinoxaline kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Abstract: Described herein are kinase inhibitors represented by Formula I: pharmaceutical compositions thereof, and uses thereof including but not limited to uses in treatment of cancer.

Abstract: A computer-implemented method includes receiving one or more log files. Each of the one or more log files includes one or more logs. The computer-implemented method further includes extracting one or more event records from said one or more logs. The computer-implemented method further includes, for each event record of the one or more event records, determining one or more attributes and one or more dimensions based on the event record, respectively. The computer-implemented method further includes grouping the one or more event records into one or more attribute groups. The computer-implemented method further includes ordering the one or more event records of each of the one or more attribute groups by the one or more dimensions. The computer-implemented method further includes generating one or more graphical representations of the one or more attribute groups. A corresponding computer system and computer program product are also disclosed.

Abstract: Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described.