Abstract: A shower control system has a controller and a control panel. The control panel includes a knob. The top surface of the knob has an inner ring and an outer ring; the outer ring has outlet buttons corresponding to a first outlet and a second outlet; when the outlet button is touched, the circuit of the controller sends a signal to the electromagnetic valve to open the first outlet or the second outlet; the inner ring is disposed with a display screen with a temperature displaying area, a volume displaying area, a temperature adjusting mode icon, a volume adjusting mode icon and a lock mode icon; when the knob is long pressed, the control panel is open, the inner ring lights up; the temperature displaying area, the volume displaying area of the displayer screen respectively displays the temperature and volume last used, and the lock mode icon is selected.

Abstract: A cool water draining device of a bathtub includes a main body, a waterway switch valve, a flow regulating valve; the waterway switch valve and the flow regulating valve are disposed at the outlet passage of the main body; the flow regulating valve is disposed with a temperature control passage and a normal open passage; the waterway switch valve is disposed with an inlet and an outlet, the inlet keeps connected to the outlet passage; when the waterway switch valve is in the initial position, the outlet is connected to the temperature control passage; when the waterway switch valve is switched to a first gear, the outlet is connected to the normal open passage; when the waterway switch valve is switched to the second gear, the outlet is closed; the temperature control passage has a static element, a moving element and a thermal element.

Abstract: The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, m, R1, R2, R3, R3, R3, R4, R5 and R9 are as defined herein. The present invention also relates to compositions comprising at least one Fused Tricyclic Heterocycle Derivative, and methods of using the Fused Tricyclic Heterocycle Derivatives for treating or preventing HIV infection in a subject.

Abstract: A lever type switch valve has a switch chamber with three sections in the axial direction including, two outlet cavities at two ends and an inlet cavity in the central section. The outer end of each outlet cavity in the axial direction has a slide section; an inner protruding ring is disposed between two ends of the inlet cavity and the outlet cavities; a spindle of dumbbell shape, the spindle is slidably coupled to the inner side of the switch chamber axially; the spindle has three sections in the axial direction that are two pistons at two ends and a flowing section in the central section; the piston has a big outer end and a small inner end. The outer ends of the pistons are slidably coupled to the slide section in sealing way, the axial length of the outlet cavity is larger than the axial direction of the piston.

Abstract: A concealed embedded component for a waterway system includes a lower main body with a cool water inlet passage, a hot water inlet passage, a mixing water passage and at least an outlet passage; an embedded box including a box body and a fixing frame covering the box body; a water testing element with the bottom surface disposed with a first passage and a second passage. The lower main body is disposed in the box body, the water testing element is disposed in the box body, the water testing element covers the lower main body to constitute the outlet passage, and the mixing water passage is connected to the cool water inlet passage or the hot water inlet passage. Since the lower main body is disposed in the box body and is separated from concrete, it is convenient to disassemble the concealed embedded component for maintenance.

Abstract: The present invention relates to Spirocyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, R1, R2 and R4 are as defined herein. The present invention also relates to compositions comprising at least one Spirocyclic Heterocycle Compound, and methods of using the Spirocyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.

Abstract: A cool water draining device of a bathtub includes a main body, a waterway switch valve, a flow regulating valve; the waterway switch valve and the flow regulating valve are disposed at the outlet passage of the main body; the flow regulating valve is disposed with a temperature control passage and a normal open passage; the waterway switch valve is disposed with an inlet and an outlet, the inlet keeps connected to the outlet passage; when the waterway switch valve is in the initial position, the outlet is connected to the temperature control passage; when the waterway switch valve is switched to a first gear, the outlet is connected to the normal open passage; when the waterway switch valve is switched to the second gear, the outlet is closed; the temperature control passage has a static element, a moving element and a thermal element.

Abstract: An outlet device includes an electronic outlet and mechanical outlet two modes. The outlet device has a mechanical outlet control device, an electronic outlet control device and a central control module; the central control module comprises a first outlet passage controlled by the mechanical outlet control device, a second outlet passage controlled by the electronic outlet control device and a central controller; the first outlet passage is disposed with a sensor, the second outlet passage is disposed with an electromagnet valve; when the mechanical outlet control device controls the first outlet passage to open, the sensor detects water flowing in the first outlet passage, whether the electromagnet valve opens or not, the central controller switches the electromagnet valve to normal close state.

Abstract: The present invention relates to Spirocyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, R1, R2 and R11 are as defined herein. The present invention also relates to compositions comprising at least one Spirocyclic Heterocycle Compound, and methods of using the Spirocyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.

Abstract: The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8, A, X and n are as defined herein. The present invention also relates to compositions comprising at least one Fused Tricyclic Heterocycle Derivative, and methods of using the Fused Tricyclic Heterocycle Derivatives for treating or preventing HIV infection in a subject.

Abstract: The present invention is provided with a rationed outlet device, wherein the outlet device comprises an outlet control switch, a volume option switch and a process control module; the volume option switch is connected to an encoder, the encoder is disposed with an unlimited outlet gear and a plurality of rationed outlet gears; the process control module comprises an outlet valve, a flow meter and a control chip; the outlet control switch and the volume option switch are independently disposed, by switching the volume option switch to set the encoder in a proper outlet gear and operating the outlet control switch, water flows out of the tap. The present invention can switch between the rationed outlet and the unlimited outlet. The volume option and the outlet control use two independent switches to control that avoids misoperation.

Abstract: The present invention relates to a pyrrole-substituted indolone derivative, a preparation method therefor, a composition comprising the derivative, and use thereof. The pyrrole-substituted indolone derivative has a structure shown in formula (I) below. The present invention further relates to use of the pyrrole-substituted indolone derivative for treating receptor tyrosine kinase-mediated diseases, and to a pharmaceutical composition comprising compounds having such a structure for treating related diseases such as tumors.

Abstract: The present invention is provided with a concealed embedded component, which comprises a lower main body with a cool water inlet passage, a hot water inlet passage, a mixing water passage and at least an outlet passage,; an embedded box, comprising a box body and a fixing frame covering the box body, a water testing element with the bottom surface disposed with a first passage and a second passage; the lower main body is disposed in the box body, the water testing element is disposed in the box body, the water testing element covers the lower main body to make the outlet passage, the mixing water passage connected to the cool water inlet passage or the hot water inlet passage. The lower main body is disposed in the box body to be separated from the concrete, it is convenient to disassemble for maintenance.

Abstract: The present invention relates to a pyrrole-substituted indolone derivative, a preparation method therefor, a composition comprising the derivative, and use thereof. The pyrrole-substituted indolone derivative has a structure shown in formula (I) below. The present invention further relates to use of the pyrrole-substituted indolone derivative for treating receptor tyrosine kinase-mediated diseases, and to a pharmaceutical composition comprising compounds having such a structure for treating related diseases such as tumors.

Abstract: The present invention relates to Spirocyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, R1, R2 and R11 are as defined herein. The present invention also relates to compositions comprising at least one Spirocyclic Heterocycle Compound, and methods of using the Spirocyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.

Abstract: A lever type switch valve has a switch chamber with three sections in the axial direction including, two outlet cavities at two ends and an inlet cavity in the central section. The outer end of each outlet cavity in the axial direction has a slide section; an inner protruding ring is disposed between two ends of the inlet cavity and the outlet cavities; a spindle of dumbbell shape, the spindle is slidably coupled to the inner side of the switch chamber axially; the spindle has three sections in the axial direction that are two pistons at two ends and a flowing section in the central section; the piston has a big outer end and a small inner end. The outer ends of the pistons are slidably coupled to the slide section in sealing way, the axial length of the outlet cavity is larger than the axial direction of the piston.

Abstract: The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8, A, X and n are as defined herein. The present invention also relates to compositions comprising at least one Fused Tricyclic Heterocycle Derivative, and methods of using the Fused Tricyclic Heterocycle Derivatives for treating or preventing HIV infection in a subject.

Abstract: The present invention provides a class of bufadienolide derivatives representing by the following formula I or pharmaceutically acceptable salts thereof, the preparing process thereof, pharmaceutical composition comprising the same and the use thereof. The bufadienolide derivatives have inhibitory activities against human-derived tumor cell lines, and thus can be used as a drug for treating malignancies.

Abstract: High throughput and virtual screening methods are disclosed that can identify potential anti-viral agents. The virtual screening methods identify agents that interact with a viral nucleoprotein binding site. The high throughput methods identify compounds that inhibit viral infection by binding to viral nucleoprotein. Also disclosed are pharmaceutical formulations useful for treating or preventing viral infections, especially influenza A.

Abstract: The invention provides vinblastine derivatives represented by the following formula 1 or their physiologically acceptable salts, their preparation, use and pharmaceutical compositions comprising the said derivatives. The said vinblastine derivatives show inhibiting activities against tumor cell lines and can be used as medicaments for treating malignant tumors.