Patents by Inventor Ling Chu

Ling Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190161430
    Abstract: A series of novel bis(hydroxymethyl) alkanoate derivatives of curcuminoids were designed, and synthesized, which show anticancer activity, and in particular to breast cancer, colon cancer, and prostate cancer.
    Type: Application
    Filed: June 2, 2017
    Publication date: May 30, 2019
    Inventors: SHENG-CHU KUO, KUO-HSIUNG LEE, CHANG-HAI TSAI, MIN-TSANG HSIEH, LING-CHU CHANG, HSIN-YI HUNG, HUI-YI LIN, JAI-SING YANG
  • Patent number: 9906935
    Abstract: A Bluetooth low energy (BLE) beacon device and a BLE advertising method are provided. The BLE advertising method includes: enabling a broadcast action with different advertising packets simultaneously, wherein the advertising packets include connectable and unconnectable advertising packets; setting advertising time information of the advertising packets; setting advertising data and an advertising packet address code; and executing the broadcast action for the advertising packets in sequence according to the advertising time information and the type of each of the advertising packets.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: February 27, 2018
    Assignee: MICROCHIP TECHNOLOGY INCORPORATED
    Inventors: Chung-I Lee, Hsin-Ling Chu, Li-Wei Chang
  • Patent number: 9718835
    Abstract: The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: August 1, 2017
    Assignees: CHINA MEDICAL UNIVERSITY HOSPITAL, THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Kuo-Hsiung Lee, Keduo Qian, Xiaoming Yang, Masuo Goto, Ying-Qian Liu, Yong-Long Zhao, Liu Yang, Mei-Juan Wang, Zhi-Jun Zhang, Tian-Shung Wu, Che-Ming Teng, Chih-Ya Wang, Shiow-Lin Pan, Sheng-Chu Kuo, Hsin-Yi Hung, Ling-Chu Chang, Yang-Chang Wu, Min-Tsang Hsieh, Chung Y. Hsu, Woei-Cherng Shyu, Chen-Huan Lin
  • Patent number: 9675681
    Abstract: A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular Streptococcus pneumoniae lysate broth is described. Ultrafiltering and diafiltering a clarified S. pneumoniae lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting S. pneumoniae serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: June 13, 2017
    Assignee: Wyeth LLC
    Inventors: Yonghui Yuan, Mark Ruppen, Wei-Qiang Sun, Ling Chu, John Simpson, James Patch, Justin Keith Moran, Pamela S. Fink
  • Publication number: 20160229862
    Abstract: The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
    Type: Application
    Filed: September 26, 2014
    Publication date: August 11, 2016
    Inventors: Kuo-Hsiung LEE, Keduo QIAN, Xiaoming YANG, Masuo GOTO, Ying-Qian LIU, Yong-Long ZHAO, Liu YANG, Mei-Juan WANG, Zhi-Jun ZHANG, Tian-Shung WU, Che-Ming TENG, Chih-Ya WANG, Shiow-Lin PAN, Sheng-Chu KUO, Hsin-Yi HUNG, Ling-Chu CHANG, Yang-Chang WU, Min-Tsang HSIEH, Chung Y. HSU, Woei-Cherng SHYU, Chen-Huan LIN
  • Publication number: 20160095047
    Abstract: A Bluetooth low energy (BLE) beacon device and a BLE advertising method are provided. The BLE advertising method includes: enabling a broadcast action with different advertising packets simultaneously, wherein the advertising packets include connectable and unconnectable advertising packets; setting advertising time information of the advertising packets; setting advertising data and an advertising packet address code; and executing the broadcast action for the advertising packets in sequence according to the advertising time information and the type of each of the advertising packets.
    Type: Application
    Filed: December 9, 2014
    Publication date: March 31, 2016
    Applicant: ISSC TECHNOLOGIES CORP.
    Inventors: Chung-I Lee, Hsin-Ling Chu, Li-Wei Chang
  • Patent number: 9301086
    Abstract: A data transmission system and a data transmission method for a Bluetooth interface are provided. The data transmission system includes a central electronic apparatus and a peripheral electronic apparatus. The central electronic apparatus has a central Bluetooth module, and the peripheral electronic apparatus has a peripheral Bluetooth module. Some Bluetooth characteristic information are transmitted between the central Bluetooth module and the peripheral Bluetooth module, wherein the characteristic information indicates a plurality of pieces of buffer size information in the central and peripheral Bluetooth modules. The central and peripheral Bluetooth modules perform a data transmission operation therebetween based on the characteristic information through a central enable flag and a peripheral Bluetooth module enable flag respectively.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: March 29, 2016
    Assignee: MICROCHIP TECHNOLOGY INCORPORATED
    Inventors: Chung-I Lee, Hsin-Ling Chu
  • Patent number: 9266813
    Abstract: The present invention provides a series of derivatives of stilbenoid which are useful as new inhibitory agents against head and neck squamous cell carcinoma (HNSCC) and hepatoma.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: February 23, 2016
    Assignee: China Medical University
    Inventors: Sheng-Chu Kuo, Jai-Sing Yang, Min-Tsang Hsieh, Tian-Shung Wu, Kuo-Hsiung Lee, Huei-Wen Chen, Li-Jiau Huang, Hsin-Yi Hung, Tzong-Der Way, Ling-Chu Chang, Hui-Yi Lin, Yung-Yi Cheng, Chin-Yu Liu
  • Publication number: 20150296325
    Abstract: A data transmission system and a data transmission method for a Bluetooth interface are provided. The data transmission system includes a central electronic apparatus and a peripheral electronic apparatus. The central electronic apparatus has a central Bluetooth module, and the peripheral electronic apparatus has a peripheral Bluetooth module. Some Bluetooth characteristic information are transmitted between the central Bluetooth module and the peripheral Bluetooth module, wherein the characteristic information indicates a plurality of pieces of buffer size information in the central and peripheral Bluetooth modules. The central and peripheral Bluetooth modules perform a data transmission operation therebetween based on the characteristic information through a central enable flag and a peripheral Bluetooth module enable flag respectively.
    Type: Application
    Filed: July 25, 2014
    Publication date: October 15, 2015
    Inventors: Chung-I Lee, Hsin-Ling Chu
  • Publication number: 20150165017
    Abstract: A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular Streptococcus pneumoniae lysate broth is described. Ultrafiltering and diafiltering a clarified S. pneumoniae lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting S. pneumoniae serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F.
    Type: Application
    Filed: February 27, 2015
    Publication date: June 18, 2015
    Inventors: Yonghui Yuan, Mark Ruppen, Wei-Qiang Sun, Ling Chu, John Simpson, James Patch, Justin Keith Moran, Pamela Fink Charbonneau
  • Publication number: 20150143613
    Abstract: A solar-powered ventilated hat with light-chasing function comprising an inner hat body to be worn on the head and an outer hat body pivotally connected to the inner hat body. The inner hat body is designed as meshed and a plurality of positioning ribs are disposed on its surface. On the top edge of the outer hat body are disposed a fan and a servomotor pivotally connected to the top edge of the inner hat body. A light-detecting part, a solar panel and a control circuit are disposed on the brim of the outer hat body. The solar panel is electrically connected to the fan and the servomotor. When the hat is worn, the light-detecting part detects sunlight and drives the servomotor to rotate the outer hat body so that the solar panel can face sunlight directly to generate adequate electric power supply for the fan. Exterior air is guided by the fan inside the hat and distributed on the head by the inner hat body to form convection and make the head comfortable and dry.
    Type: Application
    Filed: November 28, 2013
    Publication date: May 28, 2015
    Inventor: HUA LING CHU
  • Patent number: 8999697
    Abstract: A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular Streptococcus pneumoniae lysate broth is described. Ultrafiltering and diafiltering a clarified S. pneumoniae lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting S. pneumoniae serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: April 7, 2015
    Assignee: Wyeth LLC
    Inventors: Yonghui Yuan, Mark Ruppen, Wei-Qiang Sun, Ling Chu, John Simpson, James Patch, Justin Keith Moran, Pamela Fink Charbonneau
  • Patent number: 8988740
    Abstract: A scanning method and apparatus. The method comprising the steps of: measuring an ambient video level using an area sensor under the control of a processor means; and calculating a gain and/or a exposure time and/or light source power for an actual flash video level using a stored reference flash video level and the measured ambient video level such that a summation of the actual flash video level and the ambient video level yields a desired video level in a scan image of the document using the calculated gain and/or exposure time and/or light source power.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: March 24, 2015
    Assignee: Piqx Imaging Pte Ltd
    Inventors: Yew Kien Loi, Ling Chuing Goh, Swee Heng Yeo, Boon Chen Lee, Gunawan Sutono
  • Publication number: 20140363463
    Abstract: A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular Streptococcus pneumoniae lysate broth is described. Ultrafiltering and diafiltering a clarified S. pneumoniae lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting S. pneumoniae serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F.
    Type: Application
    Filed: January 24, 2014
    Publication date: December 11, 2014
    Applicant: Wyeth LLC
    Inventors: Yonghui YUAN, Mark RUPPEN, Wei-Qiang SUN, Ling CHU, John SIMPSON, James PATCH, Justin Keith MORAN, Pamela FINK CHARBONNEAU
  • Publication number: 20140357688
    Abstract: The present invention is directed to a method for inhibiting the overexpression of EZH2 in breast cancer cells. The method comprises administering to breast cancer cells an effective amount of YC-1 (3-(5?-hydroxymethyl-2?-furyl)-1-benzyl indazole), YC-1-succinate (succinic acid mono-[5-(1-benzyl-1H-indazol-3-yl)-furan-2-ylmethyl]ester), or a pharmaceutically acceptable salt thereof. The present invention is also directed to treating breast cancer comprising administering to a subject an effective amount of YC-1-succinate.
    Type: Application
    Filed: May 28, 2014
    Publication date: December 4, 2014
    Applicant: Yung Shin Pharm. Ind. Co., Ltd.
    Inventors: Sheng-Chu Kuo, Fang-Yu Lee, Che-Ming Teng, Ling-Chu Chang, Yung-Luen Yu
  • Publication number: 20140303241
    Abstract: The present invention provides a series of derivatives of stilbenoid which are useful as new inhibitory agents against head and neck squamous cell carcinoma (HNSCC) and hepatoma.
    Type: Application
    Filed: March 28, 2014
    Publication date: October 9, 2014
    Applicant: AnnCare Bio-Tech Center Inc.
    Inventors: Sheng-Chu Kuo, Jai-Sing Yang, Min-Tsang Hsieh, Tian-Shung Wu, Kuo-Hsiung Lee, Huei-Wen Chen, Li-Jiau Huang, Hsin-Yi Hung, Tzong-Der Way, Ling-Chu Chang, Hui-Yi Lin, Yung-Yi Cheng, Chin-Yu Liu
  • Publication number: 20140293370
    Abstract: A scanning method and apparatus. The method comprising the steps of: measuring an ambient video level using an area sensor under the control of a processor means; and calculating a gain and/or a exposure time and/or light source power for an actual flash video level using a stored reference flash video level and the measured ambient video level such that a summation of the actual flash video level and the ambient video level yields a desired video level in a scan image of the document using the calculated gain and/or exposure time and/or light source power.
    Type: Application
    Filed: January 4, 2011
    Publication date: October 2, 2014
    Applicant: PIQX IMAGING PTE LTD
    Inventors: Yew Kien Loi, Ling Chuing Goh, Swee Heng Yeo, Boon Chen Lee, Gunawan Sutono
  • Publication number: 20140221879
    Abstract: A breast building and waist shaping device includes a pad body, whereon are disposed a pillow, a breast building unit and a waist shaping unit. The breast building unit includes a base body with two slot parts. A plurality of bulges, malaxating parts, massaging parts and heating parts are disposed in the slot parts. The waist shaping unit includes a slice body whereon are disposed vibrating and heating parts. Binding bands are disposed on two sides of the slice body. A user lies face-down on the pad body with the breast placed in the slot parts of the breast building unit and the binding bands of the waist shaping unit tied around the waist. In this manner, the effects of breast building and waist shaping are achieved through malaxation, vibration, massage and fomentation.
    Type: Application
    Filed: February 4, 2013
    Publication date: August 7, 2014
    Inventor: HUA LING CHU
  • Patent number: 8734950
    Abstract: A resin composition is provided. The resin composition comprises an epoxy resin and a hardener, wherein the amount of the hardener is about 10 parts by weight to about 200 parts by weight per 100 parts by weight of the epoxy resin and the hardener comprises a first styrene-maleic anhydride copolymer (SMA) copolymer and a second SMA copolymer, the first SMA copolymer has a molar ratio of styrene to maleic anhydride m1, the second SMA copolymer has a molar ratio of styrene to maleic anhydride m2, and m1?m2?3.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: May 27, 2014
    Assignee: Taiwan Union Technology Corporation
    Inventors: Hsien-Te Chen, Mei-Ling Chu, Tsung-Hsien Lin, Chih-Wei Liao
  • Patent number: 8658726
    Abstract: Desirable composites of polysiloxane polymers and inorganic nanoparticles can be formed based on the appropriate selection of the surface properties of the particles and the chemical properties of the polymer. High loadings of particles can be achieved with good dispersion through the polymer. The composites can have good optical properties. In some embodiments, the inorganic particles are substantially free of surface modification.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: February 25, 2014
    Assignee: NanoGram Corporation
    Inventors: Hui Du, Shivkumar Chiruvolu, Ang-Ling Chu