Patents by Inventor Ling Zhang

Ling Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9856509
    Abstract: The invention relates to a compound of Formula I: F1—X1-L1-X2—P1—X3-G1??(Formula I).
    Type: Grant
    Filed: May 1, 2014
    Date of Patent: January 2, 2018
    Assignee: The Broad Institute, Inc.
    Inventors: Yan-Ling Zhang, Edward Holson, Florence F. Wagner
  • Patent number: 9851814
    Abstract: A foldable mouse comprises a substrate, a thin-film battery, a touch module, a signal processing module, and a communication module. The substrate is a foldable structure. The thin-film battery is electrically connected to the touch module, the signal processing module, and the communication module; the signal processing module drives the touch module, receives signals from the touch module, and sends the signals to the communication module. The substrate comprises a main body structure sandwiched between a first support plate and a second support plate. The first support plate and the second support plate are symmetrically located at two opposite sides of the main body and foldable connected to the main body structure. The main body structure comprises a first surface and a second surface, and a minidisc is integrated on the second surface.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: December 26, 2017
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Lei Deng, Ying-Ri Sun, Guang-Hong Han, Ling Zhang, Shou-Shan Fan
  • Patent number: 9790184
    Abstract: The present invention relates to compounds of formula (I) or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein X1, X2, X3, X4, X5, W1, W2, W3, and W4 are as described. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. In one aspect, the invention relates to selective HDAC3 inhibitors useful for protecting ?-cells and improving insulin resistance. The selective HDAC3 inhibitors are also useful for promoting cognitive function and enhancing learning and memory formation.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: October 17, 2017
    Assignees: The Broad Institute, Inc., The General Hospital Corporation
    Inventors: Edward Holson, Florence Fevrier Wagner, Stephen J. Haggarty, Yan-Ling Zhang, Morten Lundh, Bridget Wagner, Michael C. Lewis, Tracey Lynn Petryshen
  • Publication number: 20170275471
    Abstract: A functionalized ethylene-based polymer dissolved in an appropriate solvent and applied to a nonpolar surface can change the surface polarity/characteristics of the nonpolar surface. This change to the surface polarity/characteristics of the nonpolar surface allows adhesion of materials, such as paint, to surfaces such as polypropylene, polyethylene and polyolefin elastomers.
    Type: Application
    Filed: November 13, 2015
    Publication date: September 28, 2017
    Inventors: Kyle Anderson, Ling Zhang-Watson
  • Patent number: 9770479
    Abstract: The present invention relates to a Rehmannia glutinasa Libosch. extract for reducing blood glucose and lipid levels and treating hematologic diseases such as leukemia, and methods for preparing the same. The extract is prepared by subjecting fresh Rehmannia glutinasa Libosch. to flux extraction, concentrating the resultant extract, dissolving the concentrated extract with water, loading the obtained solution on a column packed with macroporous adsorption resins, eluting the column with ethanol, concentrating and drying the eluate. The extract can be made into clinically acceptable forms of dosage by pharmaceutically conventional measures, including capsule, tablet, pill, granule, dropping pill and so on. The extract is stable and has catalpol content up to 90-98%. The preparing method is simple to operate and applicable to industrial-scale production.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: September 26, 2017
    Inventor: Ling Zhang
  • Patent number: 9759607
    Abstract: An optical wavelength identifying system comprises an optical wavelength detecting device, a memory, a modulator, a comparison module, and an instruction module. The optical wavelength detecting device comprises a polarizer, a detecting element, a measuring device and a data processor. The polarizer is configured to transform an incident light into a polarized light. The detecting element is configured to form a temperature difference or a potential difference, wherein the detecting element comprises a carbon nanotube structure comprising a plurality of carbon nanotubes oriented along the same direction. The measuring device is electrically connected to the detecting element and configured to measure the temperature difference or the potential difference. The data processor is electrically connected to the measuring device and configured to obtain the optical wavelength by calculating and analyzing the temperature difference or the potential difference.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: September 12, 2017
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Ling Zhang, Lei Deng, Yang Wu, Kai-Li Jiang, Jia-Ping Wang, Shou-Shan Fan
  • Publication number: 20170253994
    Abstract: A bismuth and magnesium co-doped lithium niobate crystal includes Li2CO3, Nb2O5, Bi2O3 and MgO, wherein the molar ratio of [Li] and [Nb] is 0.90-1.00, the molar percentage of Bi2O3 in the mixture is 0.25-0.80%, and the molar percentage of MgO in the mixture is 3.0-7.0%. The bismuth and magnesium co-doped lithium niobate crystal has enhanced photorefraction, improved photorefractive sensitivity, shortened holographic grating saturation writing time, and the photorefractive diffraction efficiency can reach up to 17%. The response time is only 170 ms, when the holographic storage experiment is carried out using 488 nm continuous laser. Therefore, this crystal can be used in the field of holographic imaging.
    Type: Application
    Filed: December 7, 2016
    Publication date: September 7, 2017
    Inventors: Yongfa KONG, Dahuai ZHENG, Shiguo LIU, Jingjun XU, Peiming XU, Zhiyong BIAN, Shaolin CHEN, Ling ZHANG, Hongde LIU
  • Publication number: 20170224798
    Abstract: The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are producing using electroporation in conjunction with a transposon-based integration system to produce a population of CAR-expressing cells that require minimal ex vivo expansion or that can be directly administered to patients for disease (e.g., cancer) treatment.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 10, 2017
    Inventors: Laurence JN COOPER, Hiroki TORIKAI, Ling ZHANG, Helen HULS, Feng WANG-JOHANNING, Lenka HURTON, Simon OLIVARES, Janani KRISHNAMURTHY
  • Patent number: 9729840
    Abstract: A detachable projection module and an electronic device having the same integrate an optical engine and an image processing unit into an independent detachable module, where the module case is fixedly connected to a device body of the electronic device, so that projection module can receive image signals from the electronic device and convert the received image signals into projection signals to be projected onto a surface near the device body of the electronic device. Through a dedicated or generic connector interface, the detachable projection module may be removed from one electronic device and be mounted to another electronic device, giving an electronic device capability of equipping a projection module to extend the electronic device with a secondary display or empower an electronic device, which has no display at first, with display ability.
    Type: Grant
    Filed: January 17, 2016
    Date of Patent: August 8, 2017
    Inventors: Chun-Yi Lee, Yong-Ling Zhang, Ke-Shiu Chen
  • Publication number: 20170217955
    Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R1a, R2b, R2c, R5 and t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 3, 2017
    Applicants: The Broad Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital, Massachusetts Institute of Technology
    Inventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Li-Huei Tsai, Stephen J. Haggarty, Yan-Ling Zhang
  • Publication number: 20170211978
    Abstract: An optical locking system comprises a light emitter, an optical wavelength identifying system, and a locking unit. The optical wavelength identifying system comprises an optical wavelength detecting device, a memory, a modulator, a comparison module, and an instruction module. The optical wavelength detecting device comprises a polarizer, a detecting element, a measuring device, and a data processor. The detecting element configured to form a temperature difference or a potential difference between two points of the detecting element when exposed to the polarized light, wherein the detecting element comprises a carbon nanotube structure comprising a plurality of carbon nanotubes oriented along the same direction, and angles between a polarizing direction of the polarized light and an oriented direction of the plurality of carbon nanotubes is adjustable.
    Type: Application
    Filed: January 19, 2017
    Publication date: July 27, 2017
    Inventors: LING ZHANG, LEI DENG, YANG WU, CHANG-HONG LIU, KAI-LI JIANG, SHOU-SHAN FAN
  • Publication number: 20170211986
    Abstract: An photosensitive device, the sensor comprising: a plurality of photosensitive units distributed in an array, each photosensitive unit configured to receive and convert light signal, wherein the photosensitive unit comprises a detecting element and a polarizer, the detecting element comprises a carbon nanotube structure comprising a plurality of carbon nanotubes oriented along the same direction, and the polarizer is configured to generate polarized light to irradiate a part surface of the carbon nanotube structure; a measuring device configured to measure temperature differences or potential differences generated in the carbon nanotube structure by irradiating; a data processor configured to analyze and calculate the potential differences or the temperature differences to obtain the wavelength of the light signal.
    Type: Application
    Filed: January 19, 2017
    Publication date: July 27, 2017
    Inventors: LING ZHANG, YANG WU, KAI-LI JIANG, CHANG-HONG LIU, JIA-PING WANG, SHOU-SHAN FAN
  • Publication number: 20170211980
    Abstract: An optical wavelength identifying system comprises an optical wavelength detecting device, a memory, a modulator, a comparison module, and an instruction module. The optical wavelength detecting device comprises a polarizer, a detecting element, a measuring device and a data processor. The polarizer is configured to transform an incident light into a polarized light. The detecting element is configured to form a temperature difference or a potential difference, wherein the detecting element comprises a carbon nanotube structure comprising a plurality of carbon nanotubes oriented along the same direction. The measuring device is electrically connected to the detecting element and configured to measure the temperature difference or the potential difference. The data processor is electrically connected to the measuring device and configured to obtain the optical wavelength by calculating and analyzing the temperature difference or the potential difference.
    Type: Application
    Filed: January 19, 2017
    Publication date: July 27, 2017
    Inventors: LING ZHANG, LEI DENG, YANG WU, KAI-LI JIANG, JIA-PING WANG, SHOU-SHAN FAN
  • Publication number: 20170211981
    Abstract: An optical wavelength detecting device, the device including: a polarizer configured to transform an incident light into a polarized light; a detecting element configured to receive the polarized light and form a temperature difference or a potential difference between two points of the detecting element, wherein the detecting element includes a carbon nanotube structure including a plurality of carbon nanotubes oriented along the same direction, and angles between a polarizing direction of the polarized light and an oriented direction of the plurality of carbon nanotubes is adjustable; a measuring device electrically connected to the detecting element and configured to measure the temperature difference or the potential difference; a data processor electrically connected to the measuring device and configured to obtain the optical wavelength by calculating and analyzing the temperature difference or the potential difference.
    Type: Application
    Filed: January 19, 2017
    Publication date: July 27, 2017
    Inventors: LING ZHANG, YANG WU, KAI-LI JIANG, CHANG-HONG LIU, JIA-PING WANG, SHOU-SHAN FAN
  • Publication number: 20170211985
    Abstract: An optical wavelength detecting device, the device including: a polarizer configured to transform an incident light into a polarized light; a detecting element configured to receive the polarized light and form a temperature difference or a potential difference between two points of the detecting element, wherein the detecting element comprises a carbon nanotube structure including a plurality of carbon nanotubes oriented along the same direction, and angles between a polarizing direction of the polarized light and an oriented direction of the plurality of carbon nanotubes is adjustable; a measuring device electrically connected to the detecting element and configured to measure the temperature difference or the potential difference; a data processor electrically connected to the measuring device and configured to obtain the optical wavelength by calculating and analyzing the temperature difference or the potential difference.
    Type: Application
    Filed: January 19, 2017
    Publication date: July 27, 2017
    Inventors: LING ZHANG, YANG WU, KAI-LI JIANG, CHANG-HONG LIU, JIA-PING WANG, SHOU-SHAN FAN
  • Patent number: 9705988
    Abstract: Embodiments of the present invention may share common data among multiple servers. According to one embodiment of the present invention, a code segment is obtained at a first server from a client in response to the client interacting with a first application hosted on the first server, where the code segment is associated with business logic in the first application. Then, the first application is executed based on the code segment.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: July 11, 2017
    Assignee: International Business Machines Corporation
    Inventors: Hai Bin Dai, Xiao Feng Yu, Ling Zhang
  • Patent number: 9674309
    Abstract: Embodiments of the present invention may share common data among multiple servers. According to one embodiment of the present invention, a code segment is obtained at a first server from a client in response to the client interacting with a first application hosted on the first server, where the code segment is associated with business logic in the first application. Then, the first application is executed based on the code segment.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: June 6, 2017
    Assignee: International Business Machines Corporation
    Inventors: Hai Bin Dai, Xiao Feng Yu, Ling Zhang
  • Publication number: 20170121455
    Abstract: A liquid titanium-based catalyst and method for preparing polyester polymer thereof are disclosed herein. The catalyst is made by tetrabutyl titanate, 1-4 butanediol, phosphate ester, hydroxycarboxylic acid, TEOS, acetates of metal element through heating reactions in an appropriate amount of solvent. While the catalyst maintains a high activity, the synthetic slices have good hue, with high molecular weight, stable property, resistance to hydrolysis, moreover, the catalyst is a stable multicomponent liquid catalyst based on titanium, silicon. It can be directly added or diluted to add to the raw material ester or oligoester to be poly-condensed used for synthesis of polyesters which can be used in the production of fibers, engineering plastics, films, PET bottles, sheets and profiles, etc.
    Type: Application
    Filed: June 10, 2015
    Publication date: May 4, 2017
    Applicant: Anqing Hexing Chemical., Ltd.
    Inventors: Shijin MA, Yuegang BAO, Yun MA, Ling ZHANG, Yuxiu QIAN
  • Patent number: 9629877
    Abstract: The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are producing using electroporation in conjunction with a transposon-based integration system to produce a population of CAR-expressing cells that require minimal ex vivo expansion or that can be directly administered to patients for disease (e.g., cancer) treatment.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: April 25, 2017
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Laurence JN Cooper, Hiroki Torikai, Ling Zhang, Helen Huls, Feng Wang-Johanning, Lenka Hurton, Simon Olivares, Janani Krishnamurthy
  • Publication number: 20170093989
    Abstract: Embodiments of the present invention may share common data among multiple servers. According to one embodiment of the present invention, a code segment is obtained at a first server from a client in response to the client interacting with a first application hosted on the first server, where the code segment is associated with business logic in the first application. Then, the first application is executed based on the code segment.
    Type: Application
    Filed: September 25, 2015
    Publication date: March 30, 2017
    Inventors: Hai Bin Dai, Xiao Feng Yu, Ling Zhang