Patents by Inventor Ling Zhang

Ling Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CROSS DOMAIN REGISTRATION AND AUTHORIZATION
    Publication number: 20190386994
    Abstract: The present invention generally relates to computer security, and more specifically, related to registration and authorization cross multiple domains. In an aspect, a computer-implemented method, computer-implemented system, and computer program product for cross domain registration by a source domain is provided. A request is sent by a source domain to register the source domain as a trusted domain of a target domain. An approval of the request is received by the source domain. The source domain issues a key to an application of the source domain for accessing the target domain.
    Type: Application
    Filed: June 13, 2018
    Publication date: December 19, 2019
    Inventor: Ling Zhang
  • Camera using photosensitive device
    Patent number: 10488265
    Abstract: An camera, the camera including: an photosensitive device and an image processor, wherein the photosensitive device includes a plurality of photosensitive units, a measuring device and a data processor; the plurality of photosensitive units are distributed in an array, wherein each photosensitive unit is configured to receive and convert light signal to form a temperature difference or a potential difference; the measuring device is configured to measure the temperature difference or the potential difference; a data processor is configured to analyze and calculate the potential difference or the temperature difference.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: November 26, 2019
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Ling Zhang, Yang Wu, Kai-Li Jiang, Chang-Hong Liu, Jia-Ping Wang, Shou-Shan Fan
  • DOPAMINE D2 RECEPTOR LIGANDS
    Publication number: 20190345105
    Abstract: The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.
    Type: Application
    Filed: December 18, 2015
    Publication date: November 14, 2019
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Edward Scolnick, Michelle Palmer, Michael C. Lewis, Jennifer Q. Pan, Yan-Ling Zhang, Qihong Xu
  • Anti-sclerostin antibody, antigen binding fragment and medical use thereof
    Patent number: 10449250
    Abstract: Provided is a humanized antibody and chimeric antibody that specifically binds human sclerostin. The antibodies can be used for treating human bone metabolism related diseases such as osteoporosis (OP).
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: October 22, 2019
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Jiajian Liu, Yayuan Fu, Haoying Zhang, Yifang Wang, Zhen Zhang, Ling Zhang, Dongbing Cui, Lianshan Zhang, Weikang Tao
  • THROMBIN ANTIBODY, ANTIGEN-BINDING FRAGMENT AND PHARMACEUTICAL USE THEREOF
    Publication number: 20190315886
    Abstract: Provided are a thrombin antibody, an antigen-binding fragment and a pharmaceutical use thereof. Further provided are a chimeric antibody and a humanized antibody comprising a thrombin antibody CDR region, and a pharmaceutical composition comprising the thrombin antibody and the antigen-binding fragment thereof, as well as the use thereof as an anticoagulant drug. In particular, provided is a use of the humanized thrombin antibody in preparing a drug for treating a thrombin-mediated disease or condition.
    Type: Application
    Filed: February 3, 2017
    Publication date: October 17, 2019
    Inventors: Hua YING, Jiajian LIU, Yayuan FU, Ling ZHANG, Haoying ZHANG, Jiakang SUN, Lianshan ZHANG, Weikang TAO, Piaoyang SUN, Qiyue HU
  • MICROSCOPY SAMPLE STAGE FOR GAS HYDRATE TESTS AND TEMPERATURE AND PRESSURE CONTROLLING SYSTEM OF THE STAGE
    Publication number: 20190317125
    Abstract: A microscopy sample stage includes a microscope carrier platform, a heating conductor mounting on the microscope carrier platform, and a pressure cover covering the sample groove for providing high pressure for the sample groove. The heating conductor includes a sample groove. The microscopy sample stage further includes a temperature sensor for detecting temperature of the sample groove, a heating resistance for heating the sample groove and a pipeline for transmitting refrigeration medium, the temperature sensor and the heating resistance are mounted on a bottom surface of the sample groove, and the pipeline is arranged inside the heat conductor surrounding the sample groove.
    Type: Application
    Filed: April 16, 2019
    Publication date: October 17, 2019
    Inventors: Fulong Ning, Li Peng, Wei Li, Dongdong Wang, Ling Zhang, Wenjia Ou, Zhun Zhang, Zhong Zou
  • Mounting structure for hard disk drives
    Patent number: 10416729
    Abstract: A hard disk drive mounting assembly that includes a disk drive assembly having a base structure that includes a screw hole and a damping insert at least partially surrounding the screw hole. The disk drive assembly further includes a threaded insert positioned in the screw hole of the damping insert.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: September 17, 2019
    Assignee: Seagate Technology LLC
    Inventors: Hao Sun, Aravind Pitty, Xiong Liu, Ling Ling Zhang
  • HIGH GROWTH RATE DEPOSITION FOR GROUP III/V MATERIALS
    Publication number: 20190272994
    Abstract: Aspects of the disclosure relate to processes for epitaxial growth of III-V compound of (Al)GaInP material at high rates, such as about 8 ?m/hr, 10 ?m/hr, 20 ?m/hr, 30 ?m/hr, 40 ?m/hr, and 8-120 ?m/hr deposition rates. The high growth-rate deposited (Al)InGaP materials or films may be utilized in solar, semiconductor, or other electronic device applications. The Group III/V materials may be formed or grown on a sacrificial layer disposed on or over the support substrate during a chemical vapor deposition process. Subsequently, the Group III/V materials may be removed from the support substrate during an epitaxial lift off (ELO) process. The Group III/V materials are thin films of epitaxially grown layers containing gallium aluminum indium phosphide, gallium indium phosphide, derivatives thereof, alloys thereof, or combinations thereof.
    Type: Application
    Filed: May 14, 2019
    Publication date: September 5, 2019
    Inventors: Nikhil JAIN, Jason M. JEWELL, Chaowei WANG, Ji WU, Emmett Edward PERL, Claudio Andrés CAÑIZARES, Ling ZHANG, Brendan M. KAYES
  • 3,4-BIPYRIDYL PYRAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL APPLICATION THEREOF
    Publication number: 20190270724
    Abstract: The present invention relates to a 3,4-bipyridyl pyrazole derivative, and a preparation method therefor and a medical application thereof. Specifically, the present invention relates to a new 3,4-bipyridyl pyrazole derivative as shown in formula (I), a preparation method for the derivative, a pharmaceutical composition containing the derivative, a use of the derivative as a therapeutic agent, in particular as a TGF-? inhibitor, and a use of the derivative in the preparation of a drug which treats, prevents or reduces cancer mediated by TGF-? overexpression. The substituents in formula (I) have the same definitions as in the description.
    Type: Application
    Filed: November 13, 2017
    Publication date: September 5, 2019
    Inventors: Fanglong Yang, Ling Zhang, Guangyuan Shen, Feng He, Weikang Tao
  • Benzopiperidine derivative, preparation method thereof and medical use thereof
    Patent number: 10398689
    Abstract: The present invention relates to a benzopiperidine derivative, a preparation method thereof and a medical use thereof. In particular, the present invention relates to a benzopiperidine derivative as shown by general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative, as well as a use thereof as an estrogen receptor modulator in the prevention and/or treatment of estrogen receptor-mediated or dependent diseases or conditions. Preferably, the disease is breast cancer. The substituents in the general formula (I) are the same as those defined in the description.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 3, 2019
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Fanglong Yang, Ling Zhang, Chunfei Wang, Mingxun He, Qiyue Hu, Feng He, Weikang Tao, Piaoyang Sun
  • Component connector servicer
    Patent number: 10335839
    Abstract: A system includes a body having a front end and a back end, a channel within the body that is configured to hold at least a portion of a service unit, a guiderail extending along a portion of the channel and configured to couple with a pushrod, and an adapter configured to couple with a portion of the service unit and a portion of the body. The channel also includes a front opening positioned proximate to the front end of the body, wherein the front opening is configured to allow at least a portion of the service unit, or at least a portion of a connector, to pass through the front opening, and a back opening positioned proximate to the back end of the body, wherein the back opening is configured to allow at least a portion of the pushrod to pass through the back opening.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: July 2, 2019
    Assignee: Lockheed Martin Corporation
    Inventors: Michael Vincent Wozniak, Ling Zhang Larson, Floyd A. Fazi, Jr., Jeffrey Allen Lucas, Stephen R. Wood
  • ONE TYPE OF PASTA ROLLER WITH A BUILT-IN MOTOR FOR MANUAL AND ELECTRIC PASTA ROLLER MACHINE
    Publication number: 20190183133
    Abstract: A pasta roller with a built-in motor for manual and electric pasta roller machine includes a first shaft and a Direction Current motor received in a main roller. The first shaft is fixed to the main roller. The Direction Current motor drives the first shaft in one direction via a planet reduction gear unit. A second shaft is co-axially located in the main roller and has a first end gear mounted thereto. A secondary roller is located beside the main roller and has a second end gear connected to one end thereof. The first and second end gears are engaged with each other. A crank is removably inserted into a hole in the first shaft. When in manual operation, the crank is rotated to rotate the main roller and the second shaft, and the secondary roller is rotated by the engagement between the first and second end gears.
    Type: Application
    Filed: November 13, 2018
    Publication date: June 20, 2019
    Inventors: LIANG LI, RUI-LING ZHANG
  • Application of naringenin and naringin in tumor radiotherapy
    Patent number: 10307393
    Abstract: The present invention provides applications of a small molecular flavonoid compound in preparing a medication for sensitizing/synergizing tumor radiation therapy as well as reducing radioactive damage. The small molecular flavonoid compound can be naringenin, hesperetin, luteolin and apigenin, etc. The medication contains a small molecular flavonoid compound and a plurality of conventional pharmaceutical additives; wherein the small molecular flavonoid compound is an active ingredient.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: June 4, 2019
    Assignees: INSTITUTE OF BIOPHYSICS CHINESE ACADEMY OF SCIENCES, TOPFOND PHARMACEUTICAL CO., LTD.
    Inventors: Wei Liang, Chun Ling Zhang, Wen Feng Zeng, Chao Zhang, Luo Yang Wang
  • CAMERA USING PHOTOSENSITIVE DEVICE
    Publication number: 20190137345
    Abstract: An camera, the camera including: an photosensitive device and an image processor, wherein the photosensitive device includes a plurality of photosensitive units, a measuring device and a data processor; the plurality of photosensitive units are distributed in an array, wherein each photosensitive unit is configured to receive and convert light signal to form a temperature difference or a potential difference; the measuring device is configured to measure the temperature difference or the potential difference; a data processor is configured to analyze and calculate the potential difference or the temperature difference.
    Type: Application
    Filed: December 27, 2018
    Publication date: May 9, 2019
    Inventors: LING ZHANG, YANG WU, KAI-LI JIANG, CHANG-HONG LIU, JIA-PING WANG, SHOU-SHAN FAN
  • Polyolefin polyols as surface modifying agents
    Patent number: 10266703
    Abstract: A functionalized ethylene-based polymer dissolved in an appropriate solvent and applied to a nonpolar surface can change the surface polarity/characteristics of the nonpolar surface. This change to the surface polarity/characteristics of the nonpolar surface allows adhesion of materials, such as paint, to surfaces such as polypropylene, polyethylene and polyolefin elastomers.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: April 23, 2019
    Assignee: Dow Global Technologies LLC
    Inventors: Kyle Anderson, Ling Zhang-Watson
  • OPTICAL SYSTEM FOR FIBER OPTIC TERMINI
    Publication number: 20190064444
    Abstract: A system includes a first optical fiber having a first fiber face at a first end. The system further includes a second optical fiber having a second fiber face at a second end. The first end and the second end are separated by a distance. The system also includes a first lens coupled to the first fiber face at the first end, and a second lens coupled to the second fiber face at the second end.
    Type: Application
    Filed: August 25, 2017
    Publication date: February 28, 2019
    Inventors: Mike Ivor Jones, Kurt M. Chankaya, Ling Zhang Larson, Darrel John Russell, Effort Toplin, JR., Ryan B. Haygood, Richard Parker McElveen, JR.
  • Photosensitive device and camera using the same
    Patent number: 10209134
    Abstract: An photosensitive device, the sensor comprising: a plurality of photosensitive units distributed in an array, each photosensitive unit configured to receive and convert light signal, wherein the photosensitive unit comprises a detecting element and a polarizer, the detecting element comprises a carbon nanotube structure comprising a plurality of carbon nanotubes oriented along the same direction, and the polarizer is configured to generate polarized light to irradiate a part surface of the carbon nanotube structure; a measuring device configured to measure temperature differences or potential differences generated in the carbon nanotube structure by irradiating; a data processor configured to analyze and calculate the potential differences or the temperature differences to obtain the wavelength of the light signal.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: February 19, 2019
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Ling Zhang, Yang Wu, Kai-Li Jiang, Chang-Hong Liu, Jia-Ping Wang, Shou-Shan Fan
  • Data Caching and Resource Request Response
    Publication number: 20190052693
    Abstract: A data caching method and device, and a resource request response method and device. The data caching method comprise: receiving a resource request for group content belonging to a specific user group, the resource request being sent from a user terminal to an application server by a user; checking if a mapping between the group content and a group caching ID for identifying the user group and a mapping between the user and the group caching ID have been established in the caching server; and returning the group content cached in the caching server to the user terminal in responses to the mapping between the group content and the group caching ID and the mapping between the user and the group caching ID having been established in the caching server.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Inventor: Ling Zhang
  • DOPAMINE D2 RECEPTOR LIGANDS
    Publication number: 20190023656
    Abstract: The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.
    Type: Application
    Filed: December 18, 2015
    Publication date: January 24, 2019
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Edward Scolnick, Michelle Palmer, Michael C. Lewis, Jennifer Q. Pan, Yan-Ling Zhang, Qihong Xu
  • BENZOPIPERIDINE DERIVATIVE, PREPARATION METHOD THEREOF AND MEDICAL USE THEREOF
    Publication number: 20180318284
    Abstract: The present invention relates to a benzopiperidine derivative, a preparation method thereof and a medical use thereof. In particular, the present invention relates to a benzopiperidine derivative as shown by general formula (I), a preparation method thereof and a pharmaceutical composition containing the derivative, as well as a use thereof as an estrogen receptor modulator in the prevention and/or treatment of estrogen receptor-mediated or dependent diseases or conditions. Preferably, the disease is breast cancer. The substituents in the general formula (I) are the same as those defined in the description.
    Type: Application
    Filed: December 2, 2016
    Publication date: November 8, 2018
    Inventors: Fanglong YANG, Ling ZHANG, Chunfei WANG, Mingxun HE, Qiyue HU, Feng HE, Weikang TAO, Piaoyang SUN