Patents by Inventor Lixiao Wang

Lixiao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug releasing coatings for medical devices
    Patent number: 8403910
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. The additive has a hydrophilic part and a hydrophobic part and the therapeutic agent is not enclosed in micelles or encapsulated in particles or controlled release carriers.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: March 26, 2013
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • Drug releasing coatings for medical devices
    Patent number: 8404300
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. The additive has a hydrophilic part and a hydrophobic part and the therapeutic agent is not enclosed in micelles or encapsulated in particles or controlled release carriers.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: March 26, 2013
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • Drug releasing coatings for medical devices
    Patent number: 8366660
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. The additive has a hydrophilic part and a hydrophobic part and the therapeutic agent is not enclosed in micelles or encapsulated in particles or controlled release carriers.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: February 5, 2013
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • Drug releasing coatings for medical devices
    Patent number: 8366662
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: February 5, 2013
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • Radiation sterilized medical devices comprising radiation sensitive polymers
    Patent number: 8337968
    Abstract: A medical device, for instance a device inserted into the body such as catheter or a balloon, at least a portion of which is made of a thermoplastic polymeric material. The thermoplastic polymeric material comprises a blend or laminate of an aromatic protectant polymer and a radiation sensitive polymer, and/or the polymeric material includes a stabilizer against radiation oxidative degradation. The device is sterilized by exposure to high energy radiation.
    Type: Grant
    Filed: September 11, 2002
    Date of Patent: December 25, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Lixiao Wang, John Jianhua Chen
  • Medical Device Balloons with Improved Strength Properties and Processes for Producing the Same
    Publication number: 20120323301
    Abstract: A tubular parison for forming a medical device balloon. The parison is formed of a polymeric material, for instance a thermoplastic elastomer. The parison has an elongation at break which is not more than 80% of the elongation of the bulk polymeric material. The elongation of the parison is controlled by altering extrusion conditions. Balloons prepared from the parisons provide higher wall strength and/or higher inflation durability than balloons prepared from conventional parisons of the same material.
    Type: Application
    Filed: August 24, 2012
    Publication date: December 20, 2012
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Lixiao Wang, John Jianhua Chen, Jeffrey S. Lindquist, Nao Pao Lee, Douglas A. Devens
  • Balloon catheter tip design
    Patent number: 8303537
    Abstract: The present invention is directed to distal tip designs for catheter, wherein distal tip material is positioned about an inner shaft. The distal tip material may also be used as a tie layer for thermally bonding two incompatible materials together, such as a waist portion of a balloon to the inner shaft.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: November 6, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Thomas J. Holman, Daniel Keith Tomaschko, Leo M. Klisch, Richard Olson, Joseph M. Lyver, Richard Dunn, Nie Tang, Lixiao Wang, David Griswold
  • Drug releasing coatings for medical devices
    Patent number: 8241249
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: August 14, 2012
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • Drug releasing coatings for medical devices
    Patent number: 8244344
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: August 14, 2012
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • EMBOLIC PROTECTION SYSTEMS FOR BIFURCATED CONDUITS
    Publication number: 20120172967
    Abstract: An apparatus for removing emboli from a vessel during an interventional procedure comprising a catheter. The catheter includes: an elongate member having a lumen extending from the proximal end to the distal end; a dilation element disposed on a distal portion of the elongate member, the dilation element having a contracted state and an expanded state; an occlusion element disposed on a distal portion of the elongate member, the occlusion element being disposed proximal of the dilation element, and the occlusion element having a contracted state and an expanded state; and one or more aspiration ports disposed on a distal portion of the elongate member, the one or more aspiration ports being in fluid communication with the lumen, and one or more of the aspiration ports being disposed proximal of the dilation element and distal of the occlusion element.
    Type: Application
    Filed: March 7, 2012
    Publication date: July 5, 2012
    Applicant: TYCO HEALTHCARE GROUP LP
    Inventors: Lixiao Wang, Martin Chambers
  • Embolic protection systems for bifurcated conduits
    Patent number: 8172792
    Abstract: An apparatus for removing emboli from a vessel during an interventional procedure comprising a catheter. The catheter includes: an elongate member having a lumen extending from the proximal end to the distal end; a dilation element disposed on a distal portion of the elongate member, the dilation element having a contracted state and an expanded state; an occlusion element disposed on a distal portion of the elongate member, the occlusion element being disposed proximal of the dilation element, and the occlusion element having a contracted state and an expanded state; and one or more aspiration ports disposed on a distal portion of the elongate member, the one or more aspiration ports being in fluid communication with the lumen, and one or more of the aspiration ports being disposed proximal of the dilation element and distal of the occlusion element.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: May 8, 2012
    Assignee: Tyco Healthcare Group LP
    Inventors: Lixiao Wang, Martin Chambers
  • DRUG RELEASING COATINGS FOR MEDICAL DEVICES
    Publication number: 20120035530
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
    Type: Application
    Filed: October 13, 2011
    Publication date: February 9, 2012
    Inventor: Lixiao WANG
  • DRUG RELEASING COATINGS FOR MEDICAL DEVICES
    Publication number: 20120029426
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
    Type: Application
    Filed: October 13, 2011
    Publication date: February 2, 2012
    Inventor: Lixiao WANG
  • Medical device
    Patent number: 7985234
    Abstract: A medical device includes an inflatable balloon formed having portions of different materials, and a cutting element carried by the balloon. The materials can have different distensibility and/or compliancy.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: July 26, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Lixiao Wang, Steve Wu, Ronald A. Sahatjian, Albert Chin, Peter Dayton
  • CATHETER HAVING AN IMPROVED BALLOON-TO-CATHETER BOND
    Publication number: 20110172599
    Abstract: A balloon catheter assembly includes a first tubular member with a proximal portion and a distal portion and a lumen extending between the proximal portion and the distal portion. A balloon has a proximal waist length, a distal waist length and an expandable region therebetween disposed about the distal portion. A tie layer is disposed between the proximal waist length or distal waist length and the first tubular member. The tie layer comprises a polyester polymer and a polyamide polymer.
    Type: Application
    Filed: March 28, 2011
    Publication date: July 14, 2011
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: John Chen, Nie Tang, Ed Parsonage, Paul Miller, Lixiao Wang
  • DRUG RELEASING COATINGS FOR MEDICAL DEVICES
    Publication number: 20110166548
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. The additive has a hydrophilic part and a hydrophobic part and the therapeutic agent is not enclosed in micelles or encapsulated in particles or controlled release carriers.
    Type: Application
    Filed: March 7, 2011
    Publication date: July 7, 2011
    Inventor: Lixiao WANG
  • DRUG RELEASING COATINGS FOR MEDICAL DEVICES
    Publication number: 20110160660
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
    Type: Application
    Filed: March 7, 2011
    Publication date: June 30, 2011
    Inventor: Lixiao WANG
  • DRUG RELEASING COATINGS FOR MEDICAL DEVICES
    Publication number: 20110159169
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. The additive has a hydrophilic part and a hydrophobic part and the therapeutic agent is not enclosed in micelles or encapsulated in particles or controlled release carriers.
    Type: Application
    Filed: March 7, 2011
    Publication date: June 30, 2011
    Inventor: Lixiao WANG
  • DRUG RELEASING COATINGS FOR MEDICAL DEVICES
    Publication number: 20110160658
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. The additive has a hydrophilic part and a hydrophobic part and the therapeutic agent is not enclosed in micelles or encapsulated in particles or controlled release carriers.
    Type: Application
    Filed: March 7, 2011
    Publication date: June 30, 2011
    Inventor: Lixiao WANG
  • Multilayer medical device
    Patent number: 7947059
    Abstract: A medical device such as a tube or a balloon including wall structure with multiple layers. The wall structure can distribute stress, resulting in reduced defect propagation and failure.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: May 24, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Albert C. C. Chin, John Jianhua Chen, Yiqun Wang, David W. Lodin, Lixiao Wang, Ronald A. Sahatjian, Ismail Guler, Robert Burgmeier