Patents by Inventor Lixiao Wang

Lixiao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRUG COATED BALLOON CATHETERS FOR NONVASCULAR STRICTURES
    Publication number: 20200254148
    Abstract: Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 13, 2020
    Inventor: Lixiao Wang
  • Drug coated balloon catheters for nonvascular strictures
    Patent number: 10675386
    Abstract: Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.
    Type: Grant
    Filed: February 5, 2019
    Date of Patent: June 9, 2020
    Assignee: Urotronic, Inc.
    Inventor: Lixiao Wang
  • Drug coated balloon catheters for nonvascular strictures
    Patent number: 10668188
    Abstract: Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: June 2, 2020
    Assignee: Urotronic, Inc.
    Inventor: Lixiao Wang
  • DRUG RELEASING COATINGS FOR BALLOON CATHETERS
    Publication number: 20200155810
    Abstract: Balloon catheters, methods for preparing balloon catheters, and uses of balloon catheters are disclosed. The balloon catheter includes an elongate member, an expandable balloon, and a coating layer overlying an exterior surface of the expandable balloon. The coating layer includes a total drug load of a hydrophobic therapeutic agent and a combination of additives including a first additive and a second additive. The hydrophobic therapeutic agent is paclitaxel, rapamycin, or paclitaxel and rapamycin. The first additive is a surfactant. The second additive is a chemical compound having one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide, or ester groups.
    Type: Application
    Filed: October 17, 2019
    Publication date: May 21, 2020
    Inventor: Lixiao Wang
  • DRUG RELEASING COATINGS FOR BALLOON CATHETERS
    Publication number: 20200155811
    Abstract: Balloon catheters, methods for preparing balloon catheters, and uses of balloon catheters are disclosed. The balloon catheter includes an elongate member, an expandable balloon, and a coating layer overlying an exterior surface of the expandable balloon. The coating layer includes a total drug load of a hydrophobic therapeutic agent and a combination of additives including a first additive and a second additive. The hydrophobic therapeutic agent is paclitaxel, rapamycin, or paclitaxel and rapamycin. The first additive is a surfactant. The second additive is a chemical compound having one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide, or ester groups.
    Type: Application
    Filed: October 17, 2019
    Publication date: May 21, 2020
    Inventor: Lixiao Wang
  • CHEMICAL ABLATION AND METHOD OF TREATMENT FOR VARIOUS DISEASES
    Publication number: 20200086093
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, nonalcoholic fatty liver disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Application
    Filed: November 21, 2019
    Publication date: March 19, 2020
    Inventor: Lixiao Wang
  • Chemical ablation and method of treatment for various diseases
    Patent number: 10537375
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, nonalcoholic fatty liver disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: January 21, 2020
    Assignee: Neurotronic, Inc.
    Inventor: Lixiao Wang
  • CHEMICAL ABLATION AND METHOD OF TREATMENT FOR VARIOUS DISEASES
    Publication number: 20200016379
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Application
    Filed: September 6, 2019
    Publication date: January 16, 2020
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang
  • CHEMICAL ABLATION AND METHOD OF TREATMENT FOR VARIOUS DISEASES
    Publication number: 20200009355
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Application
    Filed: September 6, 2019
    Publication date: January 9, 2020
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang
  • CHEMICAL ABLATION FORMULATIONS AND METHODS OF TREATMENTS FOR VARIOUS DISEASES
    Publication number: 20190388147
    Abstract: Embodiments of the present invention are directed to the treatment of hypertension, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pains, asthma, pulmonary arterial hypertension, and chronic obstructive pulmonary disease by delivering of an effective amount of formulations at desired temperature to target tissue. The formulations include gases, vapors, liquids, solutions, emulsions and suspensions of one or more ingredients. The temperature may enhance safety and efficacy of the formulations for the treatments. The amounts of the formulation and/or energy are effective to injury or damage the tissues to have a benefit of symptom relive.
    Type: Application
    Filed: September 6, 2019
    Publication date: December 26, 2019
    Inventor: Lixiao Wang
  • BALLOON CATHETERS FOR BODY LUMENS
    Publication number: 20190374685
    Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
    Type: Application
    Filed: July 23, 2019
    Publication date: December 12, 2019
    Inventors: Lixiao Wang, Peter Barnett
  • Drug releasing coatings for balloon catheters
    Patent number: 10485959
    Abstract: Balloon catheters, methods for preparing balloon catheters, and uses of balloon catheters are disclosed. The balloon catheter includes an elongate member, an expandable balloon, and a coating layer overlying an exterior surface of the expandable balloon. The coating layer includes a total drug load of a hydrophobic therapeutic agent and a combination of additives including a first additive and a second additive. The hydrophobic therapeutic agent is paclitaxel, rapamycin, or paclitaxel and rapamycin. The first additive is a surfactant. The second additive is a chemical compound having one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide, or ester groups.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: November 26, 2019
    Assignee: LUTONIX, INC.
    Inventor: Lixiao Wang
  • Drug releasing coatings for balloon catheters
    Patent number: 10485958
    Abstract: Balloon catheters, methods for preparing balloon catheters, and uses of balloon catheters are disclosed. The balloon catheter includes an elongate member, an expandable balloon, and a coating layer overlying an exterior surface of the expandable balloon. The coating layer includes a total drug load of a hydrophobic therapeutic agent and a combination of additives including a first additive and a second additive. The hydrophobic therapeutic agent is paclitaxel, rapamycin, or paclitaxel and rapamycin. The first additive is a surfactant. The second additive is a chemical compound having one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide, or ester groups.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: November 26, 2019
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • BALLOON CATHETERS FOR BODY LUMENS
    Publication number: 20190344053
    Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
    Type: Application
    Filed: July 23, 2019
    Publication date: November 14, 2019
    Inventors: Lixiao Wang, Peter Barnett
  • CHEMICAL ABLATION FORMULATIONS AND METHODS OF TREATMENTS FOR VARIOUS DISEASES
    Publication number: 20190307507
    Abstract: Embodiments of the present invention are directed to the treatment of hypertension, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pains, asthma, pulmonary arterial hypertension, and chronic obstructive pulmonary disease by delivering of an effective amount of formulations at desired temperature to target tissue. The formulations include gases, vapors, liquids, solutions, emulsions and suspensions of one or more ingredients. The temperature may enhance safety and efficacy of the formulations for the treatments. The amounts of the formulation and/or energy are effective to injury or damage the tissues to have a benefit of symptom relive.
    Type: Application
    Filed: May 22, 2019
    Publication date: October 10, 2019
    Inventor: Lixiao Wang
  • Implant and delivery system with multiple marker interlocks
    Patent number: 10433992
    Abstract: An implant delivery system has one or more interlock assemblies which connect the implant delivery catheter to the implant, an improved inner tubular member and an outer tubular member. The interlock assemblies, improved inner tubular member and outer tubular member cooperate to place the implant in tension during deployment, thereby reducing implant deployment force.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: October 8, 2019
    Assignee: Covidien LP
    Inventors: Lixiao Wang, Jianlu Ma, Joe Tatalovich, Peggy Waltz, Keith Smythe, Richard Kusleika
  • MAGNETIC ANASTOMOSIS DEVICES
    Publication number: 20190274687
    Abstract: Embodiments of the present invention provide a magnetic anastomosis device (MAD), a delivery catheter for the MAD, and a method for treating at least one of diabetes, obesity, digestive disease, and non-alcoholic fatty liver disease. In embodiments of the present invention, a pair of the MADs are delivered in body lumen by endoscopic and/or laparoscopic techniques. An anastomosis between two adjacent body lumens is formed by compression of the pair of MADs followed by necrosis and regeneration of the lumen tissue. The bodily fluids are then redirected through the formed anastomosis to relieve disease symptoms.
    Type: Application
    Filed: September 20, 2017
    Publication date: September 12, 2019
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang, Craig C. Belton, Shannon R. Stroud, Richard Cornelius, Scott Naisbitt
  • Implant delivery system with interlocked RX port orientation
    Patent number: 10315011
    Abstract: A medical implant delivery system maintains an orientation between a guidewire lumen of an inner member of the system and a rapid-exchange port in an outer member. The medical device is disposed intermediate the inner and outer members and in friction or pressure-fit contact with the outer member. Once the guidewire lumen of the inner member and the rapid exchange port of the outer member are oriented, the friction or pressure-fit operates to maintain the orientation until deployment of the medical implant. Orientation is further maintained by a telescoping coupling of the guide wire lumen with the rapid exchange port.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: June 11, 2019
    Assignee: Covidien LP
    Inventors: Khamla Vongphakdy, Huisun Wang, Adel Hashw, Lixiao Wang
  • DRUG COATED BALLOON CATHETERS FOR NONVASCULAR STRICTURES
    Publication number: 20190167854
    Abstract: Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.
    Type: Application
    Filed: February 5, 2019
    Publication date: June 6, 2019
    Inventor: Lixiao Wang
  • Chemical ablation and method of treatment for various diseases
    Patent number: 10286191
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue, In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: May 14, 2019
    Assignee: Neurotronic, Inc.
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang