Patents by Inventor Lothar W. Kleiner

Lothar W. Kleiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Semi-Crystalline Composition For Coating
    Publication number: 20130230564
    Abstract: The present invention provides a coating comprising a semi-crystalline polymer on an implantable device and methods of making and using the same.
    Type: Application
    Filed: February 19, 2013
    Publication date: September 5, 2013
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang, Syed Faiyaz Ahmed Hossainy, Florencia Lim, Michael Huy Ngo, O. Mikael Trollsas
  • Stent and delivery system with reduced chemical degradation including a Chitooligosaccharide
    Patent number: 8524166
    Abstract: Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: September 3, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Bin Huang, Lothar W. Kleiner, John Stankus
  • Implantable medical device coatings with improved mechanical stability
    Patent number: 8377116
    Abstract: The present invention provides an implantable medical device coating that has improved stability, a medical device coated with such coating, and a method of increasing the stability of an implantable medical device coating, wherein the coating comprises a stereocomplex f poly(D-lactic acid) and poly(L-lactice acid).
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: February 19, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Shaw Ling Hsu, Yiwen Tang, Lothar W. Kleiner, Fuh-Wei Tang, Ni Ding, Syed Faiyaz Ahmed Hossainy
  • Controlling Moisture In And Plasticization Of Bioresorbable Polymer For Melt Processing
    Publication number: 20130041129
    Abstract: Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
    Type: Application
    Filed: August 11, 2011
    Publication date: February 14, 2013
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Bethany Steichen, Stephen D. Pacetti, Manish Gada, Thierry Glauser, Lothar W. Kleiner, Yunbing Wang, James P. Oberhauser, Ni Ding
  • Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat
    Patent number: 8357390
    Abstract: The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: January 22, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang
  • Implantable drug delivery devices having alternating hydrophilic and amphiphillic polymer layers
    Patent number: 8343529
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: January 1, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F. A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Polymer tube expansion apparatus to maximize fracture toughness
    Patent number: 8303296
    Abstract: Methods of and systems for fabricating a polymeric stent with improved fracture toughness including radial expansion of a polymer tube along its entire length at the same time and fabricating a stent from the expanded tube are disclosed herein.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: November 6, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, James P. Oberhauser, Thierry Glauser, David K. Wrolstad, Yunbing Wang
  • SOLUBLE COATING COMPRISING POLYELECTROLYTE WITH HYDROPHOBIC COUNTERIONS
    Publication number: 20120276185
    Abstract: The present invention provides an implantable device having a biosoluble coating comprising a polyelectrolyte and a counterion and the methods of making and using the same.
    Type: Application
    Filed: July 9, 2012
    Publication date: November 1, 2012
    Inventors: Syed F.A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Coating Comprising An Elastin-Based Copolymer
    Publication number: 20120263759
    Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided. The copolymer may be used as a coating on a stent. Methods of using a stent coated with the copolymer are also provided.
    Type: Application
    Filed: September 2, 2011
    Publication date: October 18, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F.A. Hossainy, Yiwen Tang, Lothar W. Kleiner
  • Freeze-Thaw Method For Modifying Stent Coating
    Publication number: 20120231049
    Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 13, 2012
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Gordon Stewart, Benjamyn Serna, Lothar W. Kleiner
  • Implantable Drug Delivery Devices Having Alternating Hydrophilic And Amphiphilic Polymer Layers
    Publication number: 20120225303
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Application
    Filed: May 17, 2012
    Publication date: September 6, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F.A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Freeze-thaw method for modifying stent coating
    Patent number: 8246973
    Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: August 21, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Gordon Stewart, Benjamyn Serna, Lothar W. Kleiner
  • DRUG ELUTING IMPLANTABLE MEDICAL DEVICE WITH HEMOCOMPATIBLE AND/OR PROHEALING TOPCOAT
    Publication number: 20120209371
    Abstract: The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 16, 2012
    Applicant: Abbott Cardiovasular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang
  • DRUG ELUTING IMPLANTABLE MEDICAL DEVICE WITH HEMOCOMPATIBLE AND/OR PROHEALING TOPCOAT
    Publication number: 20120209372
    Abstract: The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 16, 2012
    Applicant: Abbott Cardiovasular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang
  • Stent And Delivery System With Reduced Chemical Degradation
    Publication number: 20120171260
    Abstract: Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed.
    Type: Application
    Filed: March 12, 2012
    Publication date: July 5, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Bin Huang, Lothar W. Kleiner, John Stankus
  • Implantable drug delivery devices having alternating hydrophilic and amphiphilic polymer layers
    Patent number: 8202529
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: June 19, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F. A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • STENT FORMED FROM CROSSLINKED BIOABSORBABLE POLYMER
    Publication number: 20120149850
    Abstract: A stent having a stent body made from a crosslinked bioabsorbable polymer is disclosed. A method of making the stent including exposing a tube formed from a bioabsorbable polymer to radiation to crosslink the bioabsorbable polymer and forming a stent body from the exposed tube is disclosed. The tube can include a crosslinking agent which induces crosslinking upon radiation exposure. Additionally or alternatively, the bioabsorbable polymer can be a copolymer that crosslinks upon exposure to radiation in the absence of a crosslinking agent.
    Type: Application
    Filed: February 17, 2012
    Publication date: June 14, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventor: Lothar W. Kleiner
  • METHOD OF MAKING A STENT FORMED FROM CROSSLINKED BIOABSORBABLE POLYMER
    Publication number: 20120150283
    Abstract: A stent having a stent body made from a crosslinked bioabsorbable polymer is disclosed. A method of making the stent including exposing a tube formed from a bioabsorbable polymer to radiation to crosslink the bioabsorbable polymer and forming a stent body from the exposed tube is disclosed. The tube can include a crosslinking agent which induces crosslinking upon radiation exposure. Additionally or alternatively, the bioabsorbable polymer can be a copolymer that crosslinks upon exposure to radiation in the absence of a crosslinking agent.
    Type: Application
    Filed: February 17, 2012
    Publication date: June 14, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventor: Lothar W. Kleiner
  • Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat
    Patent number: 8182829
    Abstract: The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: May 22, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang
  • Stent and delivery system with reduced chemical degradation
    Patent number: 8147769
    Abstract: Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: April 3, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Bin Huang, Lothar W. Kleiner, John Stankus