Abstract: The present invention provides novel pyrazolo[4,3-c]quinoline derivatives exhibiting specifically inhibition activity to microbiota ?-glucuronidase, whereby providing potent activities to prevent chemotherapy-induced diarrhea (CID) of cancers. Therefore, the compounds of the present invention can be used as (1) chemotherapy-adjuvant to prevent chemotherapy-induced diarrhea (CID) and enhance chemotherapeutic efficiency of cancers; (2) health-food supplement to prevent the carcinogens induced colon carcinoma.

Abstract: A rubber fixing apparatus and a coater are provided. The rubber fixing apparatus includes: a storing device, in which a cavity configured to receive at least one rubber and an outlet communicated with the cavity are provided; and a fixing structure provided on the storing device and outside the cavity. The rubber is moved from the cavity through the outlet in a first direction and is fixed to the fixing structure.

Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.

Abstract: Listings and reviews of listings can be processed to identify descriptive attributes for locations associated with the listings. To do this, a corpus of words is generated for various locations based on listings in the locations and reviews of those listings. An expected frequency, and per-location frequency for each word is determined. These numbers are in turn used to determine a number of high frequency listing locations, and a number of below expected frequency listing locations for each word. Based on a comparison of the number of high frequency listing locations and the number of below expected frequency listing locations of a word with an attribute reference number, the word can be identified either as an attribute that is likely descriptive of the location, or not.

Abstract: A method for processing a plurality of semiconductor wafers includes acquiring a process parameter measurement for each of the semiconductor wafers, associating each of the semiconductor wafers with one of a plurality of groups based on a respective process parameter measurement for each of the semiconductor wafers, where each respective group corresponds to a respective recipe, and for each one of the groups, processing ones of the semiconductor wafers associated with that group together according to a respective recipe.

Abstract: An array substrate, a display panel, and a display are disclosed. At least one metal layer is added to make a contact with a first metal layer of an existing GOA circuit and to partially overlap with a second metal layer and/or poly-silicon layer of the existing GOA circuit in an insulated manner to form a capacitor, which means that at least one capacitor in series connection with existing capacitors is added, so that the capacitance of the GOA circuit is increased while the capacitor area of the GOA circuit is still the area of the existing capacitors, thus, facilitating the narrow-border design of LCDs.

Abstract: Listings and reviews of listings can be processed to identify descriptive attributes for locations associated with the listings. To do this, a corpus of words is generated for various locations based on listings in the locations and reviews of those listings. An expected frequency, and per-location frequency for each word is determined. These numbers are in turn used to determine a number of high frequency listing locations, and a number of below expected frequency listing locations for each word. Based on a comparison of the number of high frequency listing locations and the number of below expected frequency listing locations of a word with an attribute reference number, the word can be identified either as an attribute that is likely descriptive of the location, or not.

Abstract: A fixing device, an inkjet cartridge and an inkjet printing apparatus are disclosed. The fixing device includes a case body. The case body includes a front end and a rear end and provided with at least one groove extending from the rear end to the front end, the at least one groove is provided with at least one clamper therein for fixing a work piece therein.

Abstract: A rubber fixing apparatus and a coater are provided. The rubber fixing apparatus includes: a storing device, in which a cavity configured to receive at least one rubber and an outlet communicated with the cavity are provided; and a fixing structure provided on the storing device and outside the cavity. The rubber is moved from the cavity through the outlet in a first direction and is fixed to the fixing structure.

Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppresses the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.

Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.

Abstract: The present invention is related to a method for detecting a protein comprising: (1) providing a fusion protein, wherein the fusion protein comprises the protein which is fused with a secondary antibody detected protein tag, wherein the secondary antibody detected protein tag comprises at least one epitope selected from the Fc region of at least one primary antibody which is capable of being detected by a corresponding secondary antibody; (2) contacting the fusion protein with a secondary antibody which binds to the secondary antibody detected protein tag to form a protein/antibody complex; and (3) detecting the protein/antibody complex.

Abstract: A fixing device, an inkjet cartridge and an inkjet printing apparatus are disclosed. The fixing device includes a case body. The case body includes a front end and a rear end and provided with at least one groove extending from the rear end to the front end, the at least one groove is provided with at least one clamper therein for fixing a work piece therein.

Abstract: The present invention provides novel pyrazolo[4,3-c]quinoline derivatives exhibiting specifically inhibition activity to microbiota ?-glucuronidase, whereby providing potent activities to prevent chemotherapy-induced diarrhea (CID) of cancers. Therefore, the compounds of the present invention can be used as (1) chemotherapy-adjuvant to prevent chemotherapy-induced diarrhea (CID) and enhance chemotherapeutic efficiency of cancers; (2) health-food supplement to prevent the carcinogens induced colon carcinoma.

Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppresses the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.

Abstract: The present invention is related to a method for detecting a protein comprising: (1) providing a fusion protein, wherein the fusion protein comprises the protein which is fused with a secondary antibody detected protein tag, wherein the secondary antibody detected protein tag comprises at least one epitope selected from the Fc region of at least one primary antibody which is capable of being detected by a corresponding secondary antibody; (2) contacting the fusion protein with a secondary antibody which binds to the secondary antibody detected protein tag to form a protein/antibody complex; and (3) detecting the protein/antibody complex.

Abstract: A method of preparing an epitope for a secondary antibody detected protein tag, comprising: constructing a expressing vector, comprising a nucleotide sequence for encoding the secondary antibody detected protein tag comprising at least one epitope selected from at least one primary antibody which is detected by corresponding secondary antibody; expressing the vector in a host cell; and obtaining the secondary antibody detected protein tag which is expressed in the host cell. Further, a method for constructing a protein molecular weight marker ladder, comprising constructing a plurality of recombinant protein tags with different molecular weights, wherein each the recombinant protein tag comprises at least one epitope of primary antibody. Besides, a secondary antibody detected protein tag comprises at least two peptide sequences of epitopes selected from primary antibodies of at least two different species.