Abstract: A metal chelator compound having the following structure: wherein: L1 is a linker containing 2-8 carbon atoms; R1 and R2 are independently selected from hydrocarbon groups containing 1-12 carbon atoms, and each one of R1 and R2 is substituted with at least one group selected from: carboxy groups —C(O) OR?; phosphoryl groups —P(?O)(OH)R?; oxy groups OR?; amino groups —NR?2; and amido groups —C(O)NHR?2; wherein R? is independently selected from H and hydrocarbon groups containing 1-6 carbon atoms and R? is selected from OH and hydrocarbon groups containing 1-6 carbon atoms; and R3 and R4 are independently selected from hydrocarbon groups (optionally fluorinated) containing 4-30 carbon atoms. Also described herein is a hydrophobic solution containing one or more metal chelators under Formula (I), metal-ligand complexes containing a metal chelator under Formula (I), and a method of separating rare earth elements from an aqueous solution by use of the hydrophobic solution.

Abstract: A method for preparing 2,5-hexanedione using 5-chloromethylfurfural, the method includes the following steps: adding the 5-chloromethylfurfural, a catalyst, polymethylhydrosiloxane, tetrahydrofuran, and water into a reaction vessel to catalyze a synthesis of the 2,5-hexanedione from the 5-chloromethylfurfural.

Abstract: An anti-overload torque sensor based on thin film sputtering includes an output cable, a circuit board, a cushion column, a shell, an elastic body, strain beams and thin film strain gauges. The elastic body is sequentially divided into an inner edge section, a mounting ring section and an outer edge section from inside to outside, and the mounting ring section is provided with integrally formed rectangular protrusions as the strain beams. The shell is coaxially installed on the mounting ring section of the elastic body. Strain resistors of the thin film strain gauges are sputtered on the strain beams of the elastic body by the sputtering coating technology.

Abstract: The present disclosure discloses a method for preparing dual-sensitive cellulose-based aerogel. The DAC (Dialdehyde cellulose), the DAC/PDMAEMA (poly-2-(dimethylamino)ethyl methacrylate) copolymer, the DAC/PDMAEMA/PEI (Polyethylenimine) copolymer are serially prepared, was freeze-dried to obtain a product. The product is the dual-sensitive cellulose-based aerogel, a cumulative adsorption capacity of the dual-sensitive cellulose-based aerogel is 250 mg/g, and a cumulative release amount of the dual-sensitive cellulose-based aerogel in 0.05 mol/L NaH2PO4 (pH=3-8), 0.2% NaCl (pH<3), or NaOH (pH>8) is 63-90%.

Abstract: A method for preparing 2,5-bishydroxymethylfuran using 5-chloromethylfurfural, the 5-chloromethylfurfural is transformed into the 2,5-bishydroxymethylfuran using a catalyst, a base neutralizer, sodium dithionite, and deionized water.

Abstract: A catalyst, an application, and a method for preparing 2,5-furanedicarboxylic acid by catalyzing 5-hydroxymethylfurfural in a base-free condition, which include a catalyst having the formula A/MnaBbOx-yVC, wherein A is Pt, Ru, Pd, or Au, B is Co, Ce, Cu, or Ni, a mole ratio of a and b is 1.5-14, and y=0.0-0.4.

Abstract: A method for preparing anisotropic cellulose-based hydrogel is provided. The method comprises ammoniating the dialdehyde cellulose obtained by oxidizing cellulose using sodium periodate to obtain ammoniated cellulose derivatives; performing Schiff reaction using the ammoniated cellulose derivatives and dopamine to obtain cellulose-based nanosheets; depositing Fe3O4 nanoparticles on a surface of the cellulose-based nanosheets by a deposition method to obtain magnetic cellulose-based nanosheets; and forming the anisotropic cellulose-based hydrogel using the magnetic cellulose-based nanosheets by a polymerization method.

Abstract: A method for preparing anisotropic cellulose-based hydrogel is provided. The method comprises ammoniating the dialdehyde cellulose obtained by oxidizing cellulose using sodium periodate to obtain ammoniated cellulose derivatives; performing Schiff reaction using the ammoniated cellulose derivatives and dopamine to obtain cellulose-based nanosheets; depositing Fe3O4 nanoparticles on a surface of the cellulose-based nanosheets by a deposition method to obtain magnetic cellulose-based nanosheets; and forming the anisotropic cellulose-based hydrogel using the magnetic cellulose-based nanosheets by a polymerization method.

Abstract: Bimetal oxide catalyst and methods, a method comprises: mixing and grinding to obtain a mixture comprising a manganese salt (a), at least one of other metal salt (b), and an additive (c), wherein the other metal salt comprises at least one of a copper salt, a cobalt salt, a cerium salt, an iron salt, or a nickel salt, and the additive comprises at least one of polyol or organic acid, and calcining the mixture to obtain the bimetal oxide catalyst.

Abstract: An autoinducer-2 (AI-2) molecular response-based starting element and an Escherichia coli (E. coli) dynamic regulation system and method constructed thereby are provided. A cell density-dependent starting element PJ23119-LsrR-PlsrA based on an AI-2 molecular response is constructed. The element can be used to self-induce the expression of dCpf1, and crRNAs of different target genes are further assembled, such that the self-inducible element can be used for dCpf1-CRP to achieve the dynamic regulation of genes in a synthesis pathway. In the present disclosure, vectors pACYDuet-PJ23119-LsrR-PlsrA-dCpf1-CRP, pRSFDuet-GFP-mCherry, and pETDuet-crRNA can be constructed to simultaneously achieve the transcriptional activation and inhibition of different genes. The construction method of recombinant E. coli in the present disclosure is simple and has promising application prospects.

Abstract: A preparation method of an anti-PD-1/PD-L1 monoclonal antibody (mAb)-induced autoimmune myocarditis model is provided, including: mediating a model with adeno-associated virus 9 (AAV9) to achieve the high expression of PDL1 in a myocardial tissue, and applying an anti-PD-1/PD-L1 mAb to the model with high PDL1 expression in the myocardial tissue for modeling. The present disclosure also provides use of an animal model prepared by the preparation method. The model prepared by the present disclosure truly simulates the pathogenesis and clinical course of autoimmune myocarditis in a patient administered with an anti-PD1/PD-L1 mAb, is close to a pathophysiological status of a clinical patient, has a high modeling rate, and can be dynamically monitored.

Abstract: A preparation method of an anti-PD-1/PD-L1 monoclonal antibody (mAb)-induced autoimmune myocarditis model is provided, including: mediating a model with adeno-associated virus 9 (AAV9) to achieve the high expression of PDL1 in a myocardial tissue, and applying an anti-PD-1/PD-L1 mAb to the model with high PDL1 expression in the myocardial tissue for modeling. The present disclosure also provides use of an animal model prepared by the preparation method. The model prepared by the present disclosure truly simulates the pathogenesis and clinical course of autoimmune myocarditis in a patient administered with an anti-PD1/PD-L1 mAb, is close to a pathophysiological status of a clinical patient, has a high modeling rate, and can be dynamically monitored.

Abstract: The present disclosure discloses an anti-overload torque sensor based on thin film sputtering, which includes an output cable, a circuit board, a cushion column, a shell, an elastic body, strain beams and thin film strain gauges. The elastic body is an annular plate, which is sequentially divided into an inner edge section, a mounting ring section and an outer edge section from inside to outside, and the mounting ring section is provided with integrally formed rectangular protrusions as the strain beams. The shell is coaxially installed on the mounting ring section of the elastic body. The circuit board is located in an annular cavity of the shell and is installed on the mounting ring section of the elastic body through the cushion column. One end of the output cable is welded on the circuit board, and the other end is connected with an external electrical connector. Strain resistors of the two thin film strain gauges are sputtered on the strain beams of the elastic body by the sputtering coating technology.

Abstract: Disclosed are a layered magnesium manganese composite material for copper ion adsorption, a preparation method therefor and an application thereof. The preparation method comprises: (1) dissolving a soluble magnesium salt and a soluble manganese salt in water to obtain a compound solution of the magnesium salt and the manganese salt; (2) dissolving a soluble carbonate and a soluble hydroxide in water to obtain a compound solution of the carbonate and the hydroxide; (3) dropwise adding the compound solution of the magnesium salt and the manganese salt into the compound solution obtained in step (2), stirring a mixed solution and allowing the mixed solution to age, and subjecting an obtained precipitate to centrifugation, washing, drying, grinding and sieving to obtain the layered magnesium manganese composite material for copper ion adsorption.

Abstract: Bimetal oxide catalyst and methods, a method comprises: mixing and grinding to obtain a mixture comprising a manganese salt (a), at least one of other metal salt (b), and an additive (c), wherein the other metal salt comprises at least one of a copper salt, a cobalt salt, a cerium salt, an iron salt, or a nickel salt, and the additive comprises at least one of polyol or organic acid, and calcining the mixture to obtain the bimetal oxide catalyst.

Abstract: It is an object of the present invention to diagnose image quality of a print image without using an open communication network and output the print image, a diagnosis result of image quality, and information of the print parameters while avoiding disclosure of confidential information to users. A test print control portion causes a print device to execute a test print process to form a test image on a sheet. An image quality diagnosis portion diagnoses image quality of the test image included in the image read by an image reading device. A code image generating portion generates a code image that represents information of print parameters adopted in the test print process. An output control portion causes an output device to output a diagnosis image that includes an image representing a diagnosis result of image quality of the test image, and the code image.

Abstract: It is an object of the present invention to diagnose image quality of a print image without using an open communication network and output the print image, a diagnosis result of image quality, and information of the print parameters while avoiding disclosure of confidential information to users. A test print control portion causes a print device to execute a test print process to form a test image on a sheet. An image quality diagnosis portion diagnoses image quality of the test image included in the image read by an image reading device. A code image generating portion generates a code image that represents information of print parameters adopted in the test print process. An output control portion causes an output device to output a diagnosis image that includes an image representing a diagnosis result of image quality of the test image, and the code image.

Abstract: The present disclosure discloses a method for preparing dual-sensitive cellulose-based aerogel. The DAC (Dialdehyde cellulose), the DAC/PDMAEMA (poly-2-(dimethylamino)ethyl methacrylate) copolymer, the DAC/PDMAEMA/PEI (Polyethylenimine) copolymer are serially prepared, was freeze-dried to obtain a product. The product is the dual-sensitive cellulose-based aerogel, a cumulative adsorption capacity of the dual-sensitive cellulose-based aerogel is 250 mg/g, and a cumulative release amount of the dual-sensitive cellulose-based aerogel in 0.05 mol/L NaH2PO4 (pH=3-8), 0.2% NaCl (pH<3), or NaOH (pH>8) is 63-90%.

Abstract: A hybridoma cell line of secreting meloxicam monoclonal antibodies with a preservation number of hybridoma cell line of CGMCC No. 14700 belongs to the field of food safety immunological detection. The. BALB/c mice are immunized through one time immunization with complete freund's adjuvant, three times of booster immunization with incomplete freund's adjuvant and one time of rush immunization with meroxicam complete antigen without adjuvant; the spleen cells from BALB/C mice immunized with high potency and low value of IC50 are fused with murine myeloma cells; and then the hybridoma cell line is obtained through indirect competitive ELISA screening and three sub-clones. The monoclonal antibody secreted by this cell line has good specificity and detection sensitivity to meloxicam (value of IC50 is 0.1 ng/ml), being suitable for detection of meroxicam in food.

Abstract: A hybridoma cell line of secreting meloxicam monoclonal antibodies with a preservation number of hybridoma cell line of CGMCC No. 14700 belongs to the field of food safety immunological detection. The. BALB/c mice are immunized through one time immunization with complete freund's adjuvant, three times of booster immunization with incomplete freund's adjuvant and one time of rush immunization with meroxicam complete antigen without adjuvant; the spleen cells from BALB/C mice immunized with high potency and low value of IC50 are fused with murine myeloma cells; and then the hybridoma cell line is obtained through indirect competitive ELISA screening and three sub-clones. The monoclonal antibody secreted by this cell line has good specificity and detection sensitivity to meloxicam (value of IC50 is 0.1 ng/ml), being suitable for detection of meroxicam in food.