Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that one or more mutations in segment 4 of the viral genome produces a single cycle infectious CIV (sciCIV). The sciCIV does not allow for the production of infectious progeny, but is able to induce a CIV-specific immune response.

Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.

Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.

Abstract: The invention relates to compositions and methods for preventing or treating arenavirus related diseases and disorders through the administration to a subject in need thereof a live-attenuated virus (LAV), wherein the LAV is a codon deoptimized (CD) arenavirus.

Abstract: An aircraft with a system for rearward mounting and dismounting an engine, the engine being placed inside the rear part of the aircraft when mounted. The system for rearward mounting and dismounting the engine comprises a first removable attachment device arranged to attach the engine to the fuselage in the rear part of the aircraft, internal supports fixed in the rear part of the aircraft, at least two longitudinal detachable rails, to be placed on the internal supports and under the engine, and a slider to attach to the engine via a second removable attachment device, to be placed on the longitudinal detachable rails.

Abstract: The present invention provides compositions and methods related to equine live-attenuated influenza vaccines.

Abstract: Disclosed herein are system, method, and computer program product embodiments for delivering messages using enterprise numbers. In an embodiment, a messaging system may facilitate two-way communication between enterprises and end user devices through the user of shared enterprise numbers. Multiple content providers and/or service providers may use the shared enterprise numbers to reach a wide range of end user devices. The end user devices may be, for example, telephones capable of communicating via short message service (SMS). The messaging system may assign enterprise numbers based on sessions to avoid conflicts when receiving reply messages. In an embodiment, the messaging system may assign enterprise numbers so received replies may be returned to corresponding enterprises without relying on keywords to be present in the reply message.

Abstract: An aircraft with rear mounted engines, comprising a vertical tail plane and a horizontal tail plane, in which the engines are mounted on top of the horizontal tail plane, such that the horizontal tail plane comprises an inner fixed part attached to the fuselage of the aircraft, the inner fixed part comprising an elevator, and two outer movable parts, each one of the outer movable parts being located at each side end of the horizontal tail plane which is furthest away from the fuselage of the aircraft, such that both the inner fixed part and the outer movable parts are at least partially subjected to a flow coming from the engines when the engines are in use.

Abstract: A conduit box assembly including: a housing defining an interior chamber; arms extending outward from the housing, wherein the arms each have a wall defining a passage into the chamber; a compressible seal for each of the arms, wherein each seal has an outer surface configured to seat in and abut the wall of the arm receiving the seal, and a cover configured to attached to the housing and cover an open side of the housing, wherein the cover includes arms extending outward from a center portion the cover and the arms are each configured to cover an open side of a respective one of the arms of the housing and compress the seal in the respective arm.

Abstract: A conduit box assembly including: a housing defining an interior chamber; arms extending outward from the housing, wherein the arms each have a wall defining a passage into the chamber; a compressible seal for each of the arms, wherein each seal has an outer surface configured to seat in and abut the wall of the arm receiving the seal, and a cover configured to attached to the housing and cover an open side of the housing, wherein the cover includes arms extending outward from a center portion the cover and the arms are each configured to cover an open side of a respective one of the arms of the housing and compress the seal in the respective arm.

Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that one or more mutations in segment 4 of the viral genome produces a single cycle infectious CIV (sciCIV). The sciCIV does not allow for the production of infectious progeny, but is able to induce a CIV-specific immune response.

Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.

Abstract: Disclosed are compositions and methods related to recombinant arenaviruses and their use in vaccines for the treatment or prevention of an arenavirus infection.

Abstract: Methods and systems for platform configuration management may use a platform configuration register (PCR) stored on a trusted platform module (TPM) included with an information handling system. A basic input/output system (BIOS) may include instructions to generate a first PCR value based on BIOS settings while a user is operating the BIOS. When the first PCR value indicates a change from a previous PCR value stored in the PCR, an alert may be displayed to the user and sent to a network administrator. The BIOS may display an indication of a mapping of BIOS settings to the first PCR value.

Abstract: The invention provides an aircraft with a trimmable horizontal stabilizer (13) that not requires a cut-out in resistant areas of the rear fuselage and that occupies less space that in conventional horizontal stabilizers. The rear fuselage (5) comprises at least a first section (9) having a resistant fuselage and a second section (11), aft of the first section, having a non-resistant fuselage (i.e. a fairing). The load-bearing structure (30) of the horizontal stabilizer and the trimming actuator (50) are disposed inside said second section (11). The pivot element (41) is mounted on its forward side and coupled to the first section (9) of the rear fuselage. The connection fitting (21) is mounted on its rearward side and the trimming actuator (50) is disposed so that it exerts a force in the direction of the Z-axis of the aircraft on the connection fitting (21) during a trimming operation.

Abstract: The invention relates to compositions and methods for preventing or treating arenavirus related diseases and disorders through the administration to a subject in need thereof a live-attenuated virus (LAV), wherein the LAV is a codon deoptimized (CD) arenavirus.

Abstract: To optimize the structure of an aircraft tail section, an aircraft rear section comprises a fuselage section, a tail section, and a vertical stabilizer comprising a box-section structure which comprises a box-section upper part extending on the outside of the tail section, and a box-section lower part housed inside the tail section, such that the tail section is wholly supported by the box-section structure.

Abstract: This disclosure relates to an optical system and a method for its manufacture. One embodiment of the optical system may include an optical material upon which a multilayer stack may be deposited. The multilayer stack may include a first layer composed on a first surface of the optical material, a second layer composed on the first layer, and a third layer composed on the second layer. Among other possibilities, the first layer may include Al2O3, the second layer may include Al, and the third layer may include SiO2. The multilayer stack may be a reflective coating on a surface of the optical material with optical power. Thus, the reflective coating may serve as a reflective image former within the optical system. The optical system may be configured as a head-mountable device.

Abstract: Disclosed are compositions and methods related to recombinant arenaviruses and their use in vaccines for the treatment or prevention of an arenavirus infection.