Abstract: A user interface that displays a number of cards or windows is described where a user can move the cards in a horizontal direction freely. When a card resides in a locked zone, as defined by a user, the card will be able to be manipulated in a vertical direction, while cards that reside in a regular zone will not be able to be moved vertically. In addition, only cards that are in the locked zone can be subjected to a user action such as cutting content from the card, pasting content to the card, enlarging the contents of the card, or shrinking the contents of the card.

Abstract: Provided herein are retroreflective colored article having a predetermined pattern of beaded and unbeaded regions and at least one polymeric color layer (130) covering at least a portion of the beaded and unbeaded regions, a reflector layer (140) covering the colour layer, and a carrier (150). Also disclosed are methods for making the articles.

Abstract: The present disclosure is directed to compositions and methods for coating, particularly protecting and optionally cleaning, metallic surfaces, and articles containing such surfaces.

Abstract: A method to automatically classify video content retrieved over the Internet and, in particular, to determine whether a candidate video is an instance of a source video. The method begins by sampling static image frames from each of the candidate video and the source video. Based on the sampled static image frames, a set of static image frames in the candidate video that match a corresponding set of static image frames in the source video are then identified. Metadata associated with the sets of matching static image frames are then compared to determine how closely a temporal order of the set of static image frames in the candidate video matches the temporal order of the set of static image frames in the source video. Based on a measure of temporal order match, a classification is then applied to the candidate video to complete the method.

Abstract: The disclosure is related to the idea of tracking user navigation, consumption, and/or behavior and applying analytics to help shape future offerings (customized offerings, up-sells, recommendations, etc.) to a user and to provide reporting data to service providers and studios. Methods and systems of providing viewing recommendations for a user are set forth. This involves collecting usage data related to a session of interaction by the user, processing the user data for the session, and providing feedback regarding the session. The sessions involve multiple stages tracking a user's interactions. These include stages such as an inquiry stage, a results stage, a details stage, a selection stage, and a confirmation stage. Usage data is then mined to indicate the content creator of a media asset regardless of the media asset type.

Abstract: The present invention concerns immunotherapy for cancers having cells that comprise the ganglioside GD2 antigen. In specific embodiment, T cells having a chimeric receptor that targets GD2 is employed. In particular cases, the chimeric receptor comprises antibody, cytoplasmic signaling domain from the T cell receptor, and/or costimulatory molecule(s).

Abstract: The subject invention concerns peptide mimetics of SOCS proteins and methods of use. In one embodiment, a peptide mimetic of the invention binds to a SOCS1 and a SOCS3 target protein. In a specific embodiment, a peptide mimetic of the invention comprises the amino acid sequence of SEQ ID NO:1 and/or SEQ ID NO:2 and/or SEQ ID NO:51, or a functional fragment or variant thereof. In a further embodiment, a peptide of the invention can comprise multiple copies of the mimetic sequence. In one embodiment, a peptide of the invention comprises two or more copies of SEQ ID NO:1 and/or SEQ ID NO:2 and/or SEQ ID NO:51. In a specific embodiment, a peptide mimetic of the invention comprises the amino acid sequence of SEQ ID NO:3 and/or SEQ ID NO:4 to and/or SEQ ID NO:52, or a functional fragment or variant thereof. The subject invention also pertains to methods of treating and/or preventing autoimmune conditions and/or disorders.

Abstract: According to one embodiment of the present invention, during database replication from a source database to a target database, operations applied to the source database are transferred as target operations and applied to the target database. A request from a requestor to idle a specified database object is received during the database replication. In response to receiving the request, transference of the target operations for the specified database object from the source database to the target database is terminated and target operations for the specified database object on the target database are monitored. In response to no target operations being applied to the specified database object on the target database, replication of the specified database object is suspended and the requestor is notified when the idling of the specified database object has completed.

Abstract: According to one embodiment of the present invention, during database replication from a source database to a target database, operations applied to the source database are transferred as target operations and applied to the target database. A request from a requestor to idle a specified database object is received during the database replication. In response to receiving the request, transference of the target operations for the specified database object from the source database to the target database is terminated and target operations for the specified database object on the target database are monitored. In response to no target operations being applied to the specified database object on the target database, replication of the specified database object is suspended and the requestor is notified when the idling of the specified database object has completed.

Abstract: Embodiments of the invention include methods and compositions related to improved cells encoding a chimeric antigen receptor that is specific for two or more antigens. In certain aspects the receptor encompasses two or more non-identical antigen recognition domains. The antigens are tumor antigens, in particular embodiments.

Abstract: The subject invention pertains to agonist peptides of type I interferons and methods of using the peptides. These peptides are based on the amino acid sequence of the C-terminus region of the type I IFN molecules and are capable of binding to the cytoplasmic domain of type I IFN receptors. Surprisingly, these peptides were found to possess the same or similar biological activity as that associated with the full-length, mature type I IFN proteins, even though these peptides do not bind to the extracellular domain of the type I IFN receptors. In one embodiment, the peptide is a peptide of IFN?. In another embodiment, the peptide is a peptide of IFN?. Exemplified peptides of the invention include those having SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:38, SEQ ID NO:39, and SEQ ID NO:40. The subject peptides have been shown to effect increased resistance to viral infection.

Abstract: A method for high-dose Grid radiotherapy utilizing a three-dimensional (3D) dose lattice formation is described herein. The 3D dose lattice can be achieved by, but not limited to, three technical approaches: 1) non-coplanar focused beams; 2) multileaf collimator (MLC)-based intensity modulated radiation therapy (IMRT) or aperture-modulated arc; and 3) heavy charged particle beam. The configuration of a 3D dose lattice is comprised of the number, location, and dose of dose vertices. The optimal configuration of a 3D dose lattice can be achieved by manual calculations or by automating the calculations for a generic algorithm. The objective of the optimization algorithm is to satisfy three conditions via iteration until they reach their global minimum. With 3D dose lattice, high doses of radiation are concentrated at each lattice vertex within a tumor with drastically lower doses between vertices (peak-to-valley effect), leaving tissue outside of the tumor volume minimally exposed.

Abstract: A conduit assembly and method of utilizing the assembly generally extends along a centerline for detachable engagement to a component in an axial direction. The assembly may include a body having an internal, cylindrical, surface with a first surface portion located axially adjacent to a second surface portion. The first portion is circumferentially continuous and the second portion extends circumferentially by about 180 degrees or less. A saddle is axially aligned to the second portion and detachably connects to the body. The saddle extends circumferentially by about 180 degrees or more. A conduit is received in the body and rigidly secured to the body via the saddle. A circumferentially continuous sealing interface is carried between the first portion and the conduit, and is constructed and arranged to slide axially with respect to the first portion and the conduit.

Abstract: A method and apparatus is provided for establishing a Global System for Mobile communications (GSM) call through an Unlicensed Mobile Access (UMA) Network by enabling Voice over IP (VoIP) access into a GSM network from various IP-enabled mobile device terminals and a mechanism to authenticate and use such terminals without any change to the UMA or GSM network.

Abstract: An individual uses a communication device to provide information identifying the type of emergency that the individual is experiencing. In response to receiving an emergency alert, an inquiry as to whether the received emergency alert relates to a medical emergency or to a non-medical emergency is generated and provided to the user. Upon receiving a response indicating that the emergency alert relates to a medical emergency, a medical history of the individual is automatically retrieved and a geographical location of the user is determined. A medical emergency service that is suitable for determining a type of medical assistance required by the individual is automatically identified based on the received confirmation and the retrieved medical history. A bi-directional communication with a communication device of the identified medical emergency service is established to upload to a data storage element of the communication device the medical history and geographical location of the individual.

Abstract: An individual uses a communication device to provide information identifying the type of emergency that the individual is experiencing. In response to receiving an emergency alert, an inquiry as to whether the received emergency alert relates to a medical emergency or to a non-medical emergency is generated and provided to the user. Upon receiving a response indicating that the emergency alert relates to a medical emergency, a medical history of the individual is automatically retrieved and a geographical location of the user is determined. A medical emergency service that is suitable for determining a type of medical assistance required by the individual is automatically identified based on the received confirmation and the retrieved medical history. A bi-directional communication with a communication device of the identified medical emergency service is established to upload to a data storage element of the communication device the medical history and geographical location of the individual.

Abstract: Embodiments of the invention provide for cell therapy for cancers having a TEM1 or TEM8 antigen. Certain embodiments provide for cell therapy that targets tumor vasculature, including the tumor vascular bed, for example. In specific embodiments, TEM1- and/or TEM8-specific chimeric antigen receptors are employed.

Abstract: A method of generating a display of media items includes selecting a set of icons and text items representing a set of search elements. The search elements are selected and arranged by a user on a display of the user interface. A query mapper translates the set of search elements into a set of keywords and initially weights the keywords. The keywords are scaled based on information obtained from a user preference database. A weighted query using the set of keywords and the weightings for the keywords is constructed in the query mapper and sent to a search engine. An ordered list of recommendations is provided to the user for selection of an item to playback.

Abstract: Coatings for a surface, coating compositions, articles coated with a coating, and methods of coating are disclosed in which the coating comprises a polymer blend of polyurethane as a major component and at least one other polymer P2 having in comparison to polyurethane a higher peel strength to the surface to be coated, a higher percent elongation at break when cured, and a lower glass transition temperature, the polymer blend having been cured to form a peelable and flexible layer having a textured surface.

Abstract: The present invention provides for a biocompatible drug delivery device for the targeted treatment of cancer that is implantable within the tumorous mass of a patient. In one embodiment, the device comprises two polarizable elements mechanically coupled by a connecting element. The device also comprises one or more cancer treatment agents. When the polarizable elements are depolarized, such as by the application of ionizing radiation, the two polarizable elements are repelled from each other and release the cancer treatment agent. In another embodiment, one or more treatment agents are expelled from a miniaturized syringe when internal pressure of the device is increased by the production of gas bubbles in response to the application of ionizing radiation.