Abstract: Using a bounding language to control or restrict the changes that can be made to contents of a structured document (e.g., a document encoded in the Extensible Markup Language, or “XML”), and also includes the bounding language and documents encoded according to the bounding language. A Document Type Definition (“DTD”) is defined as a “bounding DTD”, and one or more structured documents containing editing restrictions are defined according to this DTD. A processing component uses a structured document containing editing restrictions as input, and programmatically determines which fields of another structured document can be edited, which fields should be hidden, and so forth. By restricting the parts of the file that can be edited, users who need to do the editing are shielded from irrelevant details, and can carry out their task with less risk of making errors (and without needing to understand the details of the structured document markup language).

Abstract: A method of manufacturing and/or using a scaffold assembly for stem cell culture and tissue engineering applications is disclosed. The scaffold at least partially mimics a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation that uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct.

Abstract: A method of manufacturing and/or using a scaffold assembly for stem cell culture and tissue engineering applications is disclosed. The scaffold at least partially mimics a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation that uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct.

Abstract: The present invention is directed to 2,5,6-substituted morpholine derivatives and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Abstract: A method of manufacturing and/or using a scaffold assembly for stem cell culture and tissue engineering applications is disclosed. The scaffold at least partially mimics a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation that uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct.

Abstract: The present invention is directed to 5-heteroarylmorpholine derivatives and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Abstract: Using a bounding language to control or restrict the changes that can be made to contents of a structured document (e.g., a document encoded in the Extensible Markup Language, or “XML”), and also the bounding language and documents encoded according to the bounding language. A Document Type Definition (“DTD”) is defined as a “bounding DTD”, and one or more structured documents containing editing restrictions are defined according to this DTD. A processing component uses a structured document containing editing restrictions as input, and programmatically determines which fields of another structured document can be edited, which fields should be hidden, and so forth. By restricting the parts of the file that can be edited, users who need to do the editing are shielded from irrelevant details, and can carry out their task with less risk of making errors (and without needing to understand the details of the structured document markup language).

Abstract: Using a bounding language to control or restrict the changes that can be made to contents of a structured document (e.g., a document encoded in the Extensible Markup Language, or “XML”), and also includes the bounding language and documents encoded according to the bounding language. A Document Type Definition (“DTD”) is defined as a “bounding DTD”, and one or more structured documents containing editing restrictions are defined according to this DTD. A processing component uses a structured document containing editing restrictions as input, and programmatically determines which fields of another structured document can be edited, which fields should be hidden, and so forth. By restricting the parts of the file that can be edited, users who need to do the editing are shielded from irrelevant details, and can carry out their task with less risk of making errors (and without needing to understand the details of the structured document markup language).

Abstract: The present invention is directed to 2,5,6-substituted morpholine derivatives and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Abstract: The present invention is directed to 5-heteroarylmorpholine derivatives and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Abstract: A method for modifying a quality of a fruit includes cutting a live stem attached to a live fruit at a cut distance from the fruit, producing a cut end of the stem, contacting only the cut end of the stem with a solution comprising at least one mobile and quality-modifying food ingredient while protecting the fruit from contact with the solution, and keeping the cut end of the stem in contact with the solution for an incubation time sufficient to allow absorption and transport of the food ingredient into the fruit, the food ingredient conferring a modified quality upon the fruit. A system for practicing the method and an edible raw plant product produced by the method are also disclosed.

Abstract: A method for modifying a quality of a fruit includes cutting a live stem attached to a live fruit at a cut distance from the fruit, producing a cut end of the stem, contacting only the cut end of the stem with a solution comprising at least one mobile and quality-modifying food ingredient while protecting the fruit from contact with the solution, and keeping the cut end of the stem in contact with the solution for an incubation time sufficient to allow absorption and transport of the food ingredient into the fruit, the food ingredient conferring a modified quality upon the fruit. A system for practicing the method and an edible raw plant product produced by the method are also disclosed.

Abstract: A method of manufacturing and/or using a scaffold assembly for stem cell culture and tissue engineering applications is disclosed. The scaffold at least partially mimics a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation that uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct.

Abstract: A scaffold assembly and related methods of manufacturing and/or using the scaffold for stem cell culture and tissue engineering applications are disclosed which at least partially mimic a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct.

Abstract: A method for modifying a quality of a fruit includes cutting a live stem attached to a live fruit at a cut distance from the fruit, producing a cut end of the stem, contacting only the cut end of the stem with a solution comprising at least one mobile and quality-modifying food ingredient while protecting the fruit from contact with the solution, and keeping the cut end of the stem in contact with the solution for an incubation time sufficient to allow absorption and transport of the food ingredient into the fruit, the food ingredient conferring a modified quality upon the fruit. A system for practicing the method and an edible raw plant product produced by the method are also disclosed.

Abstract: A system and method for treating flowing water systems with a plasma discharge to remove or control growth of microbiological species. The system and method protect other components of the water system from being damaged by excess energy from the electrohydraulic treatment. The system and method also recycle ozone gas generated by a high voltage generator that powers the plasma discharge to further treat the water. A gas infusion system upstream of or inside a plasma reaction chamber may be used to create fine bubbles of ozone, air, or other gases in the water being treated to aid in plasma generation.

Abstract: An apparatus is disclosed for downending a vertically disposed cylindrical coil supported on an underlying pallet, with a stem projecting from the pallet through the coil. The apparatus comprises a cradle rotatable about a horizontal axis. A table on the cradle is configured and arranged to receive and retain the pallet with the coil in a vertical first position at which the coil extends across the horizontal axis. An electrically powered drive serves to rotate the cradle about the horizontal axis to translate the coil from its vertical first position to a horizontal second position.

Abstract: A system comprises a user interface configured to receive natural language input from a user. An input module couples to the user interface and is configured to process the received natural language input for selected words and phrases. A user skill determination module couples to the input module and is configured to determine a skill level of the user based on the selected words and phrases.

Abstract: A method and system are provided for aligning fibers in an electrospinning process. A jet of a fiberizable material is directed towards an uncharged collector from a dispensing location that is spaced apart from the collector. While the fiberizable material is directed towards the collector, an elliptical electric field is generated via the electrically charged dispenser and an oppositely-charged control location. The field spans between the dispensing location and the control location that is within line-of-sight of the dispensing location, and impinges upon at least a portion of the collector. Various combinations of numbers and geometries of dispensers, collectors, and electrodes can be used.

Abstract: An apparatus is disclosed for downending a vertically disposed cylindrical coil supported on an underlying pallet, with a stem projecting from the pallet through the coil. The apparatus comprises a cradle rotatable about a horizontal axis. A table on the cradle is configured and arranged to receive and retain the pallet with the coil in a vertical first position at which the coil extends across the horizontal axis. An electrically powered drive serves to rotate the cradle about the horizontal axis to translate the coil from its vertical first position to a horizontal second position.