Patents by Inventor M. Holloway
M. Holloway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110142806Abstract: A scaffold assembly and related methods of manufacturing and/or using the scaffold for stem cell culture and tissue engineering applications are disclosed which at least partially mimic a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct.Type: ApplicationFiled: December 15, 2010Publication date: June 16, 2011Applicant: USA as represented by the Administrator of the National Aeronautics and Space AdmInventors: Lisa A. Scott-Carnell, Emilie J. Siochi, Nancy M. Holloway, Kam W. Leong, Karina Kulangara
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Patent number: 7935414Abstract: An electroactive material comprises multiple layers of electroactive composite with each layer having unique dielectric, electrical and mechanical properties that define an electromechanical operation thereof when affected by an external stimulus. For example, each layer can be (i) a 2-phase composite made from a polymer with polarizable moieties and an effective amount of carbon nanotubes incorporated in the polymer for a predetermined electomechanical operation, or (ii) a 3-phase composite having the elements of the 2-phase composite and further including a third component of micro-sized to nano-sized particles of an electroactive ceramic incorporated in the polymer matrix.Type: GrantFiled: March 18, 2009Date of Patent: May 3, 2011Assignee: United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Zoubeida Ounaies, Cheol Park, Joycelyn S. Harrison, Nancy M. Holloway, Gregory K. Draughon
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Patent number: 7752683Abstract: A helmet jacket for covering and protecting a helmet and for substantially and releasably enclosing the volume inside the helmet to allow the covered helmet to function as a sealed carrying and storage container. The jacket may include elastic segments that define respective constricted openings through which the chin straps of the helmet extend on opposed sides of a releasable fastening element so that the chin straps may be used to carry the helmet while the fastened jacket material substantially encloses the volume inside the helmet to define a storage volume within the helmet.Type: GrantFiled: September 18, 2007Date of Patent: July 13, 2010Inventor: Scott M. Holloway
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Publication number: 20100068485Abstract: An electroactive material comprises multiple layers of electroactive composite with each layer having unique dielectric, electrical and mechanical properties that define an electromechanical operation thereof when affected by an external stimulus. For example, each layer can be (i) a 2-phase composite made from a polymer with polarizable moieties and an effective amount of carbon nanotubes incorporated in the polymer for a predetermined electomechanical operation, or (ii) a 3-phase composite having the elements of the 2-phase composite and further including a third component of micro-sized to nano-sized particles of an electroactive ceramic incorporated in the polymer matrix.Type: ApplicationFiled: March 18, 2009Publication date: March 18, 2010Applicant: USA as represented by the Administrator of the National Aeronautics Space AdministrationInventors: Zoubeida OUNAIES, Cheol PARK, Joycelyn S. HARRISON, Nancy M. HOLLOWAY, Gregory K. DRAUGHON
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Publication number: 20100010802Abstract: A system comprises a user interface configured to receive natural language input from a user. An input module couples to the user interface and is configured to process the received natural language input for selected words and phrases. A user skill determination module couples to the input module and is configured to determine a skill level of the user based on the selected words and phrases.Type: ApplicationFiled: July 14, 2008Publication date: January 14, 2010Applicant: International Business Machines CorporationInventors: Julio E. Ruano, Seth M. Holloway, Christopher Laffoon, Abraao Lourenco, Carl A. Timm, IV
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Patent number: 7527751Abstract: An electroactive sensing or actuating material comprises a composite made from a polymer with polarizable moieties and an effective amount of carbon nanotubes incorporated in the polymer for a predetermined electromechanical operation of the composite when such composite is affected by an external stimulus. In another embodiment, the composite comprises a third component of micro-sized to nano-sized particles of an electroactive ceramic that is also incorporated in the polymer matrix. The method for making the three-phase composite comprises either incorporating the carbon nanotubes in the polymer matrix before incorporation of the particles of ceramic or mixing the carbon nanotubes and particles of ceramic together in a solution before incorporation in the polymer matrix.Type: GrantFiled: April 25, 2008Date of Patent: May 5, 2009Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Zoubeida Ounaies, Cheol Park, Joycelyn S. Harrison, Nancy M. Holloway, Gregory K. Draughon
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Publication number: 20090108503Abstract: A method and system are provided for aligning fibers in an electrospinning process. A jet of a fiberizable material is directed towards an uncharged collector from a dispensing location that is spaced apart from the collector. While the fiberizable material is directed towards the collector, an elliptical electric field is generated via the electrically charged dispenser and an oppositely-charged control location. The field spans between the dispensing location and the control location that is within line-of-sight of the dispensing location, and impinges upon at least a portion of the collector. Various combinations of numbers and geometries of dispensers, collectors, and electrodes can be used.Type: ApplicationFiled: June 2, 2008Publication date: April 30, 2009Applicant: USA as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Lisa A. Scott-Carnell, Ralph M. Stephens, Nancy M. Holloway, Caroline Rhim, Laura Niklason, Robert L. Clark, Emilie J. Siochi
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Patent number: 7507472Abstract: An electroactive material comprises multiple layers of electroactive composite with each layer having unique dielectric, electrical and mechanical properties that define an electromechanical operation thereof when affected by an external stimulus. For example, each layer can be (i) a 2-phase composite made from a polymer with polarizable moieties and an effective amount of carbon nanotubes incorporated in the polymer for a predetermined electomechanical operation, or (ii) a 3-phase composite having the elements of the 2-phase composite and further including a third component of micro-sized to nano-sized particles of an electroactive ceramic incorporated in the polymer matrix.Type: GrantFiled: March 9, 2005Date of Patent: March 24, 2009Assignee: The United States of America as represented by the Administator of National Aeronatics and Space AdminstrationInventors: Zoubeida Ounaies, Cheol Park, Joycelyn S. Harrison, Nancy M. Holloway, Gregory K. Draughon
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Publication number: 20090070920Abstract: A helmet jacket for covering and protecting a helmet and for substantially and releasably enclosing the volume inside the helmet to allow the covered helmet to function as a sealed carrying and storage container. The jacket may include elastic segments that define respective constricted openings through which the chin straps of the helmet extend on opposed sides of a releasable fastening element so that the chin straps may be used to carry the helmet while the fastened jacket material substantially encloses the volume inside the helmet to define a storage volume within the helmet.Type: ApplicationFiled: September 18, 2007Publication date: March 19, 2009Inventor: Scott M. Holloway
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Sensing/Actuating Materials Made From Carbon Nanotube Polymer Composites and Methods for Making Same
Publication number: 20080287589Abstract: An electroactive sensing or actuating material comprises a composite made from a polymer with polarizable moieties and an effective amount of carbon nanotubes incorporated in the polymer for a predetermined electromechanical operation of the composite when such composite is affected by an external stimulus. In another embodiment, the composite comprises a third component of micro-sized to nano-sized particles of an electroactive ceramic that is also incorporated in the polymer matrix. The method for making the three-phase composite comprises either incorporating the carbon nanotubes in the polymer matrix before incorporation of the particles of ceramic or mixing the carbon nanotubes and particles of ceramic together in a solution before incorporation in the polymer matrix.Type: ApplicationFiled: April 25, 2008Publication date: November 20, 2008Applicants: Space AdministrationInventors: Zoubeida Ounaies, Cheol Park, Joycelyn S. Harrison, Nancy M. Holloway, Gregory K. Draughon -
Publication number: 20080282144Abstract: Using a bounding language to control or restrict the changes that can be made to contents of a structured document (e.g., a document encoded in the Extensible Markup Language, or “XML”), and also the bounding language and documents encoded according to the bounding language. A Document Type Definition (“DTD”) is defined as a “bounding DTD”, and one or more structured documents containing editing restrictions are defined according to this DTD. A processing component uses a structured document containing editing restrictions as input, and programmatically determines which fields of another structured document can be edited, which fields should be hidden, and so forth. By restricting the parts of the file that can be edited, users who need to do the editing are shielded from irrelevant details, and can carry out their task with less risk of making errors (and without needing to understand the details of the structured document markup language).Type: ApplicationFiled: April 14, 2008Publication date: November 13, 2008Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Jason M. Brown, Malcolm H. M. Holloway, Christopher J. Schaubach, Richard S. Szulewski, Lisa M. Wood
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Sensing/actuating materials made from carbon nanotube polymer composites and methods for making same
Patent number: 7402264Abstract: An electroactive sensing or actuating material comprises a composite made from a polymer with polarizable moieties and an effective amount of carbon nanotubes incorporated in the polymer for a predetermined electomechanical operation of the composite when such composite is affected by an external stimulus. In another embodiment, the composite comprises a third component of micro-sized to nano-sized particles of an electroactive ceramic that is also incorporated in the polymer matrix. The method for making the three-phase composite comprises either incorporating the carbon nanotubes in the polymer matrix before incorporation of the particles of ceramic or mixing the carbon nanotubes and particles of ceramic together in a solution before incorporation in the polymer matrix.Type: GrantFiled: March 3, 2005Date of Patent: July 22, 2008Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Zoubeida Ounaies, Cheol Park, Joycelyn S. Harrison, Nancy M. Holloway, Gregory K. Draughon -
Publication number: 20070203147Abstract: The present invention is directed to 2-aminothiazole compounds which are aspartyl protease inhibitors, and are inhibitors of both the beta-secretase enzyme and HIV protease, and that are useful in the treatment of diseases in which the beta-secretase enzyme and HIV are involved, such as Alzheimer's disease, HIV Infection and AIDS. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme and HIV protease are involved.Type: ApplicationFiled: March 25, 2005Publication date: August 30, 2007Inventors: Craig Coburn, Amy Espeseth, Shawn Stachel, David Olsen, Daria Hazuda, M. Holloway
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Patent number: 7213201Abstract: Methods, systems, computer program products, and methods of doing business by using a meta-editor to generate components (e.g., a specification of a rules language that restricts editing operations on structured documents, a specification of rules according to this language, and a graphical user interface editor that operates according to the specified rules) for use in controlling or restricting the changes that can be made to contents of a structured document (e.g., a document encoded in the Extensible Markup Language, or “XML”). A Document Type Definition (“DTD”) is generated as a “bounding DTD”, based on editing choices made using the meta editor, and one or more structured documents containing editing restrictions are generated according to this DTD and these editing choices. An editor (or editing component) is generated that programmatically determines which elements of another structured document can be edited, which elements should be hidden, and so forth.Type: GrantFiled: March 3, 2003Date of Patent: May 1, 2007Assignee: International Business Machines CorporationInventors: Jason M. Brown, Malcolm H. M. Holloway, Christopher J. Schaubach, Lisa M. Wood
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Publication number: 20070027071Abstract: The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.Type: ApplicationFiled: July 12, 2006Publication date: February 1, 2007Inventors: M. Holloway, Nigel Liverton, Steven Ludmerer, John McCauley, David Olsen, Michael Rudd, Joseph Vacca, Charles McIntyre
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Patent number: 6929241Abstract: This invention relates to a hydraulic valve (10) and an interconnected hydraulic valve system, (10, 12). Two coaxially disposed pipes (14, 20) are positioned vertically to form an annular space (11) there between. A flange (22) provided with a external seal (23) cooperates with an end of the outer pipe (20). Openings (18) formed in the inner pipe (14) regulates water flow. The inner pipe is also sealingly interconnected with a main supply pipe (12) for entry of water through opening (16). An electrical motorized hoist (26) provides for activation and operation of the hydraulic valve system.Type: GrantFiled: January 17, 2002Date of Patent: August 16, 2005Inventor: Rufus M. Holloway, Jr.
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Publication number: 20040252756Abstract: A assembly that modifies the frame rate of a 3D video signal and corresponding method are disclosed. The frame rate of the video signal can be increased by clocking a video encoder at a desired clock rate. When viewing a display of the video signal with the increased frame rate through a pair of stereo glasses, the perception of flicker can be reduced or eliminated.Type: ApplicationFiled: June 10, 2003Publication date: December 16, 2004Inventors: David Smith, Marty M. Holloway
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Publication number: 20040252966Abstract: A method of storing video data, a video capture module, and a video storage and playback assembly are disclosed. The method and assembly involve receiving an input video signal, decoding the input video signal and storing a video file corresponding to the input video signal. In addition, an interface for transferring data between a memory component where the video file is stored and a general use computer can be established.Type: ApplicationFiled: June 10, 2003Publication date: December 16, 2004Inventors: Marty M. Holloway, Rafael Moreno, David Smith, Hye Kyung Kim
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Publication number: 20040252965Abstract: A video storage and playback device having a portable design. The device can include a re-writeable memory component, a video signal input, and a video signal output. A video processor assembly can be used to convert input video signals into video files, to read the video files from the memory component and to convert video files to an output video signal. A computer compatible interface can be used to allow access to the memory component by a general purpose computer.Type: ApplicationFiled: June 10, 2003Publication date: December 16, 2004Inventors: Rafael Moreno, David Smith, Marty M. Holloway, Hye Kyung Kim
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Publication number: 20040216375Abstract: A plant container (50) having an inner member (52) containing a volume of earthen material (54) and an outer member (56) of IR reflective material. The inner member and outer member may be combined into a composite sheet of material (18) having an inner layer of material (28) providing strength and an outer layer of material (26) providing heat reflection and UV protection. The outer layer of material may be a white plastic containing titanium dioxide while the inner layer of material may be a less expensive material. In one embodiment, a prior art IR-absorbing black plastic or clay container is wrapped with a sheet of composite plastic material (18) having a white titanium dioxide-containing outer layer 26.Type: ApplicationFiled: April 22, 2004Publication date: November 4, 2004Inventor: Rufus M. Holloway Jr